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The map label for this gene is sapB [H]

Identifier: 119945853

GI number: 119945853

Start: 2668682

End: 2669650

Strand: Direct

Name: sapB [H]

Synonym: Ping_2193

Alternate gene names: 119945853

Gene position: 2668682-2669650 (Clockwise)

Preceding gene: 119945852

Following gene: 119945854

Centisome position: 58.53

GC content: 36.43

Gene sequence:

>969_bases
ATGCTTAACTATTTATTTCGGCGCTTAAATTTATTATTAATTACAGCACTTATTCTTTCCATTATTGCATTTATCATCTC
ACTTTGGTCAAATCAGGAACGCCCCGCCCAACATATTAATCTCTTTATGCTTTATTTGGATTACATGGGTAATATTTTAC
AAGGACAATGGGGAATTTCATTAATCAACCAAAAATCTCATATGATCAATGGACTGATTGCATTTTCCTCAACACTCGAA
CTCTGTTTAGTGGCTTTACTAACCTCTGTTATTATTGGTATACCGCTGGGTATTTTTGCCGGAATTTATCGTGATGGAAT
TTTGGATTATACCATTATGTCAATTGCCCTTATTGGCCTGGCACTGCCCGCATTTTGGCTGGCGATTATGCTGATTATGT
TACCTATCACCTTTGATTTAGGGCTGCCAATCGATGGCAATATCAGCCCCATCTATGAAATCCCCATGATCACCGGTTTT
CAACTGATAGATAGTCTATTAGCATCAGACTTATATGACCTGGCAGCCTTTATTGATCGTTTAACGCATCTGATATTACC
CGCCGTTGTTTTATCTTTTTTTCTAACCAGTGAAATAATTAGACTCACCCGATATTCAATATCACAAGTCATGAAAAGTA
ATTATATAAAAGCTGCAAATACTAAAGGGCTAACGGTAATACAGATTGTTTTCCGGCATGTTTTAAAAAATGCATTACCG
CCCATTATTCCTCAATTAAGACTGCAGTTAAATACGATTATTTCTATTGCAATGACGGTAGAAATTGTATTTGATGCTCA
AGGGTCGGGTGTTTGGTTATTGACCAGCATCAGAGGCGGCGATTATTTAGCGCTATCTGCAGCTGTTATCCTTATTTCAG
GATTTATTTTATTATCGAGCATAGTCATCGATATTTTACAGATGGTTATTTCCCCCACAACACGGAAAATGTTATATGCT
GATAAATAA

Upstream 100 bases:

>100_bases
TACGTATGGATGCATTTAAGACCAACATATCTGGTTTTTTGGTTGATCCTTTTACAGGTATAAACTTCCAAAATATCAAA
AAAACAGAAGCTCACTAACT

Downstream 100 bases:

>100_bases
CGAATTTAACGAGCAAAAAATACAATCCCCATTGCATTATATTTGGTCTATTTTCCTCAAAAACAATTTCGCGGTTTTTG
CCATGTGGGTCGGTATTGTG

Product: peptide ABC transporter, protein inner membrane binding component

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MLNYLFRRLNLLLITALILSIIAFIISLWSNQERPAQHINLFMLYLDYMGNILQGQWGISLINQKSHMINGLIAFSSTLE
LCLVALLTSVIIGIPLGIFAGIYRDGILDYTIMSIALIGLALPAFWLAIMLIMLPITFDLGLPIDGNISPIYEIPMITGF
QLIDSLLASDLYDLAAFIDRLTHLILPAVVLSFFLTSEIIRLTRYSISQVMKSNYIKAANTKGLTVIQIVFRHVLKNALP
PIIPQLRLQLNTIISIAMTVEIVFDAQGSGVWLLTSIRGGDYLALSAAVILISGFILLSSIVIDILQMVISPTTRKMLYA
DK

Sequences:

>Translated_322_residues
MLNYLFRRLNLLLITALILSIIAFIISLWSNQERPAQHINLFMLYLDYMGNILQGQWGISLINQKSHMINGLIAFSSTLE
LCLVALLTSVIIGIPLGIFAGIYRDGILDYTIMSIALIGLALPAFWLAIMLIMLPITFDLGLPIDGNISPIYEIPMITGF
QLIDSLLASDLYDLAAFIDRLTHLILPAVVLSFFLTSEIIRLTRYSISQVMKSNYIKAANTKGLTVIQIVFRHVLKNALP
PIIPQLRLQLNTIISIAMTVEIVFDAQGSGVWLLTSIRGGDYLALSAAVILISGFILLSSIVIDILQMVISPTTRKMLYA
DK
>Mature_322_residues
MLNYLFRRLNLLLITALILSIIAFIISLWSNQERPAQHINLFMLYLDYMGNILQGQWGISLINQKSHMINGLIAFSSTLE
LCLVALLTSVIIGIPLGIFAGIYRDGILDYTIMSIALIGLALPAFWLAIMLIMLPITFDLGLPIDGNISPIYEIPMITGF
QLIDSLLASDLYDLAAFIDRLTHLILPAVVLSFFLTSEIIRLTRYSISQVMKSNYIKAANTKGLTVIQIVFRHVLKNALP
PIIPQLRLQLNTIISIAMTVEIVFDAQGSGVWLLTSIRGGDYLALSAAVILISGFILLSSIVIDILQMVISPTTRKMLYA
DK

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4168

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787550, Length=321, Percent_Identity=37.3831775700935, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1789965, Length=341, Percent_Identity=30.4985337243402, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1787053, Length=336, Percent_Identity=27.6785714285714, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1787761, Length=254, Percent_Identity=33.4645669291339, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1787497, Length=335, Percent_Identity=26.5671641791045, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789888, Length=276, Percent_Identity=26.4492753623188, Blast_Score=104, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35740; Mature: 35740

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNYLFRRLNLLLITALILSIIAFIISLWSNQERPAQHINLFMLYLDYMGNILQGQWGIS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
LINQKSHMINGLIAFSSTLELCLVALLTSVIIGIPLGIFAGIYRDGILDYTIMSIALIGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALPAFWLAIMLIMLPITFDLGLPIDGNISPIYEIPMITGFQLIDSLLASDLYDLAAFIDR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTHLILPAVVLSFFLTSEIIRLTRYSISQVMKSNYIKAANTKGLTVIQIVFRHVLKNALP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC
PIIPQLRLQLNTIISIAMTVEIVFDAQGSGVWLLTSIRGGDYLALSAAVILISGFILLSS
CHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
IVIDILQMVISPTTRKMLYADK
HHHHHHHHHHCCCHHHHHCCCC
>Mature Secondary Structure
MLNYLFRRLNLLLITALILSIIAFIISLWSNQERPAQHINLFMLYLDYMGNILQGQWGIS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
LINQKSHMINGLIAFSSTLELCLVALLTSVIIGIPLGIFAGIYRDGILDYTIMSIALIGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALPAFWLAIMLIMLPITFDLGLPIDGNISPIYEIPMITGFQLIDSLLASDLYDLAAFIDR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTHLILPAVVLSFFLTSEIIRLTRYSISQVMKSNYIKAANTKGLTVIQIVFRHVLKNALP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC
PIIPQLRLQLNTIISIAMTVEIVFDAQGSGVWLLTSIRGGDYLALSAAVILISGFILLSS
CHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
IVIDILQMVISPTTRKMLYADK
HHHHHHHHHHCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]