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The map label for this gene is apaH

Identifier: 119944804

GI number: 119944804

Start: 1318970

End: 1319800

Strand: Reverse

Name: apaH

Synonym: Ping_1046

Alternate gene names: 119944804

Gene position: 1319800-1318970 (Counterclockwise)

Preceding gene: 119944805

Following gene: 119944802

Centisome position: 28.95

GC content: 41.28

Gene sequence:

>831_bases
GTGGCTACCTATATAGTGGGTGATGTCCACGGCTGCTTCGATGAACTTCAAGCTTTGCTTGAACTCGCGCAATTTAAAAA
AAATAAAGATCAGCTTTGGATAACCGGCGATCTTGTCGGACGGGGTCCAAAATCGCTGGAAACATTACGTTTTGTTAAAA
GCTTAGGTGACAGTGCGAAGATTGTACTGGGTAATCATGATCTGCATCTTTTGGCCATTCATCAAGGTATCCACAGTGAT
AAAGAAAGTGATAAATTAAGCGCATTATTAAATGCGCCAGACTGTGATGAATTACTGACTTGGTTGCGTTTTCAACCGCT
TTTTAGACGCCATCCTGAATTTAACTTTGTGATGGTTCATGCGGGCATATCCCCACAGTGGACTATCCAACAAGCGCAAG
GTTATGCTCAAGAAGTACAAAACATTTTGCAGGGTAATGAATTTAAAAAACTGCTTAAAAACATGTATGGCAACCACCCT
GCCTCATGGAATGATAGTTCACAGGGTATTAAGCGGTTACGTTTTATTATTAACGCATTAACCAGAATGCGTTATTGCCT
GTTAGACGGGTCATTAGAATTTTATAGCAAACTTGCCCCTGAGCAAACCGATAGCACTATCATTAAACCCTGGTTTGAAA
TTAACACGTTGGATCAGAGTAGTGACATCATCTTTGGCCATTGGGCGGCGTTATTAGGCACGGGGACTAAACAGGGAATT
TATGCTTTAGATACCGGATGCGTCTGGGGAAATAGCCTGAGTATGTTACGTTGGCAAGATAAAAAAATGTTTTCTTTTGC
TTGCCAACGCCAGAGAGTTCACAGTAAATAA

Upstream 100 bases:

>100_bases
AAATTGGCATTGATACAACCAAACGGGCAGAAAATATCAGCGTTGAAGAGTACGTTAATATTGCCAATTATGTGTTTGAT
TTAAAAGAAAATAAATAAAG

Downstream 100 bases:

>100_bases
ATCAGCTTACTCGGTCCAATGTTATAAATTGATAATTATAACTGTTTTGCGCATCGCTCTGATGCGCTTCTTTCTGTACT
TCTCGCCAATCGGCAATCAT

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MATYIVGDVHGCFDELQALLELAQFKKNKDQLWITGDLVGRGPKSLETLRFVKSLGDSAKIVLGNHDLHLLAIHQGIHSD
KESDKLSALLNAPDCDELLTWLRFQPLFRRHPEFNFVMVHAGISPQWTIQQAQGYAQEVQNILQGNEFKKLLKNMYGNHP
ASWNDSSQGIKRLRFIINALTRMRYCLLDGSLEFYSKLAPEQTDSTIIKPWFEINTLDQSSDIIFGHWAALLGTGTKQGI
YALDTGCVWGNSLSMLRWQDKKMFSFACQRQRVHSK

Sequences:

>Translated_276_residues
MATYIVGDVHGCFDELQALLELAQFKKNKDQLWITGDLVGRGPKSLETLRFVKSLGDSAKIVLGNHDLHLLAIHQGIHSD
KESDKLSALLNAPDCDELLTWLRFQPLFRRHPEFNFVMVHAGISPQWTIQQAQGYAQEVQNILQGNEFKKLLKNMYGNHP
ASWNDSSQGIKRLRFIINALTRMRYCLLDGSLEFYSKLAPEQTDSTIIKPWFEINTLDQSSDIIFGHWAALLGTGTKQGI
YALDTGCVWGNSLSMLRWQDKKMFSFACQRQRVHSK
>Mature_275_residues
ATYIVGDVHGCFDELQALLELAQFKKNKDQLWITGDLVGRGPKSLETLRFVKSLGDSAKIVLGNHDLHLLAIHQGIHSDK
ESDKLSALLNAPDCDELLTWLRFQPLFRRHPEFNFVMVHAGISPQWTIQQAQGYAQEVQNILQGNEFKKLLKNMYGNHPA
SWNDSSQGIKRLRFIINALTRMRYCLLDGSLEFYSKLAPEQTDSTIIKPWFEINTLDQSSDIIFGHWAALLGTGTKQGIY
ALDTGCVWGNSLSMLRWQDKKMFSFACQRQRVHSK

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family

Homologues:

Organism=Escherichia coli, GI1786234, Length=273, Percent_Identity=53.4798534798535, Blast_Score=313, Evalue=1e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): APAH_PSYIN (A1STS0)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942484.1
- ProteinModelPortal:   A1STS0
- SMR:   A1STS0
- STRING:   A1STS0
- GeneID:   4623906
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1046
- eggNOG:   COG0639
- HOGENOM:   HBG724457
- OMA:   LVFGHWA
- PhylomeDB:   A1STS0
- ProtClustDB:   PRK00166
- BioCyc:   PING357804:PING_1046-MONOMER
- HAMAP:   MF_00199
- InterPro:   IPR004617
- InterPro:   IPR004843
- InterPro:   IPR006186
- PANTHER:   PTHR11668
- PIRSF:   PIRSF000903
- TIGRFAMs:   TIGR00668

Pfam domain/function: PF00149 Metallophos

EC number: =3.6.1.41

Molecular weight: Translated: 31453; Mature: 31322

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYIVGDVHGCFDELQALLELAQFKKNKDQLWITGDLVGRGPKSLETLRFVKSLGDSAK
CCEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCE
IVLGNHDLHLLAIHQGIHSDKESDKLSALLNAPDCDELLTWLRFQPLFRRHPEFNFVMVH
EEECCCCEEEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCHHHHHCCCCCEEEEE
AGISPQWTIQQAQGYAQEVQNILQGNEFKKLLKNMYGNHPASWNDSSQGIKRLRFIINAL
ECCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
TRMRYCLLDGSLEFYSKLAPEQTDSTIIKPWFEINTLDQSSDIIFGHWAALLGTGTKQGI
HHHHHHHHCCCHHHHHHHCCCCCCCCEECCCEEEECCCCCCCCHHHHHHHHHCCCCCCCE
YALDTGCVWGNSLSMLRWQDKKMFSFACQRQRVHSK
EEEECCCEECCCCCCEEECHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATYIVGDVHGCFDELQALLELAQFKKNKDQLWITGDLVGRGPKSLETLRFVKSLGDSAK
CEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCE
IVLGNHDLHLLAIHQGIHSDKESDKLSALLNAPDCDELLTWLRFQPLFRRHPEFNFVMVH
EEECCCCEEEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCHHHHHCCCCCEEEEE
AGISPQWTIQQAQGYAQEVQNILQGNEFKKLLKNMYGNHPASWNDSSQGIKRLRFIINAL
ECCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
TRMRYCLLDGSLEFYSKLAPEQTDSTIIKPWFEINTLDQSSDIIFGHWAALLGTGTKQGI
HHHHHHHHCCCHHHHHHHCCCCCCCCEECCCEEEECCCCCCCCHHHHHHHHHCCCCCCCE
YALDTGCVWGNSLSMLRWQDKKMFSFACQRQRVHSK
EEEECCCEECCCCCCEEECHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA