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The map label for this gene is argE [H]

Identifier: 119944013

GI number: 119944013

Start: 287814

End: 288962

Strand: Reverse

Name: argE [H]

Synonym: Ping_0227

Alternate gene names: 119944013

Gene position: 288962-287814 (Counterclockwise)

Preceding gene: 119944019

Following gene: 119944012

Centisome position: 6.34

GC content: 44.39

Gene sequence:

>1149_bases
ATGGCTTTACCTACTTTTTTAAACCTCTACAAAGATCTTATTAAGATACCGTCCATTAGTTCAACGGATCCATCCTGGGA
TCAAAGTAACTTAAACGTCATTAATCAGCTTGCCAGCTGGTTAGAAGAGTTGGGCTTTAAAAGTGAGATACAAGCTGTCC
GCAGTGCGCCCGGTAAATACAATTTAATCGCCACACTCGGTGAGGGTGATGGGGGTTTATTACTCGCAGGTCATACGGAT
ACCGTCCCCTACGACGCGGGTAAGTGGACAACCGACCCTTTTACCTTGACGGAGAAAGACAATCGCTTATATGGTCTGGG
CAGCATTGATATGAAAGGTTTTTTTGCCTTTGTTATTGAAGTGTTAAAAGAGATCGATATCAATAAGCTGAATAAACCCC
TGCGCATTTTAGCAACCGCAGATGAAGAAACCACTATGGCCGGTGCGCAGGAAATAGCCGAACAAAAAACTTTTCGCCCG
GATTATGCCGTGATTGGCGAGCCAACGGGAATGGCGCCTGTTACCATGCATAAAGGCCATATGTCCGAGGGTATACGCAT
TACCGGCCGAAGTGGACACAGCTCAGATCCGGATAAAGGCCTAAACGCCATTGAAATAATGCATCTGGTGATTGGGGAAT
TAAAAAAAGTACAGCAACAGTTTAAAGAAAAATACCACAATCCCCACTTTGATGTGCCCTATCCAACTCTTAATTTTGGG
GCAATCAGTGGAGGCGATAGCCCCAACCGAATTTGTGGCTGCTGTGAGCTGCACATTGATATGCGTCCTATTCCGGGTAT
TACCACCAGTGAGCTATTTATTACCGTCAAACAGGCCTTGTCTGAAATTGAAAAGCGCTACCCGAAGAGTGTAGAGATTT
ACCATTTGCATGAGCCCATTCCTTCATATCAATGCCCGGCGCATTCAGACTTGATTAATAACGCTGAAATTTTCACCGGC
AACCCGGCACAGAGCGCTAATTACTGTACCGAGGCCCCTTTTATTCAACAGCTCGGCTGCGATACCATTATTTTAGGACC
GGGACACATAAGCCAGGCCCACCAGCCAAATGAGTATTTAGATCTTTCCTTTGTCAAACCAACCAAAGAAGTGATTAAAA
AATTAATTAATCACTATTGTGTAATTTAA

Upstream 100 bases:

>100_bases
CATTACATTAATACTTTCTTAACATTCATGATTCTTTGGGTGTAATATATTTTTCTGTTAGCTTACTCTCTCTTTTCTTT
ATTTTTTAAAAGGTGCTCTT

Downstream 100 bases:

>100_bases
TTACTTAATGAGGTTTTTAGATCCAATAAAGACCTTTATTTTGTGATGGATCGTTGACTGCTGACCTTAATCTGATAGTT
TATTGTTGTTACTTTATTTT

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MALPTFLNLYKDLIKIPSISSTDPSWDQSNLNVINQLASWLEELGFKSEIQAVRSAPGKYNLIATLGEGDGGLLLAGHTD
TVPYDAGKWTTDPFTLTEKDNRLYGLGSIDMKGFFAFVIEVLKEIDINKLNKPLRILATADEETTMAGAQEIAEQKTFRP
DYAVIGEPTGMAPVTMHKGHMSEGIRITGRSGHSSDPDKGLNAIEIMHLVIGELKKVQQQFKEKYHNPHFDVPYPTLNFG
AISGGDSPNRICGCCELHIDMRPIPGITTSELFITVKQALSEIEKRYPKSVEIYHLHEPIPSYQCPAHSDLINNAEIFTG
NPAQSANYCTEAPFIQQLGCDTIILGPGHISQAHQPNEYLDLSFVKPTKEVIKKLINHYCVI

Sequences:

>Translated_382_residues
MALPTFLNLYKDLIKIPSISSTDPSWDQSNLNVINQLASWLEELGFKSEIQAVRSAPGKYNLIATLGEGDGGLLLAGHTD
TVPYDAGKWTTDPFTLTEKDNRLYGLGSIDMKGFFAFVIEVLKEIDINKLNKPLRILATADEETTMAGAQEIAEQKTFRP
DYAVIGEPTGMAPVTMHKGHMSEGIRITGRSGHSSDPDKGLNAIEIMHLVIGELKKVQQQFKEKYHNPHFDVPYPTLNFG
AISGGDSPNRICGCCELHIDMRPIPGITTSELFITVKQALSEIEKRYPKSVEIYHLHEPIPSYQCPAHSDLINNAEIFTG
NPAQSANYCTEAPFIQQLGCDTIILGPGHISQAHQPNEYLDLSFVKPTKEVIKKLINHYCVI
>Mature_381_residues
ALPTFLNLYKDLIKIPSISSTDPSWDQSNLNVINQLASWLEELGFKSEIQAVRSAPGKYNLIATLGEGDGGLLLAGHTDT
VPYDAGKWTTDPFTLTEKDNRLYGLGSIDMKGFFAFVIEVLKEIDINKLNKPLRILATADEETTMAGAQEIAEQKTFRPD
YAVIGEPTGMAPVTMHKGHMSEGIRITGRSGHSSDPDKGLNAIEIMHLVIGELKKVQQQFKEKYHNPHFDVPYPTLNFGA
ISGGDSPNRICGCCELHIDMRPIPGITTSELFITVKQALSEIEKRYPKSVEIYHLHEPIPSYQCPAHSDLINNAEIFTGN
PAQSANYCTEAPFIQQLGCDTIILGPGHISQAHQPNEYLDLSFVKPTKEVIKKLINHYCVI

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=378, Percent_Identity=55.5555555555556, Blast_Score=465, Evalue=1e-132,
Organism=Escherichia coli, GI1789236, Length=377, Percent_Identity=25.4641909814324, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788816, Length=391, Percent_Identity=22.5063938618926, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17551016, Length=361, Percent_Identity=26.3157894736842, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42290; Mature: 42159

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALPTFLNLYKDLIKIPSISSTDPSWDQSNLNVINQLASWLEELGFKSEIQAVRSAPGKY
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCE
NLIATLGEGDGGLLLAGHTDTVPYDAGKWTTDPFTLTEKDNRLYGLGSIDMKGFFAFVIE
EEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCHHHHHHHHHH
VLKEIDINKLNKPLRILATADEETTMAGAQEIAEQKTFRPDYAVIGEPTGMAPVTMHKGH
HHHHCCHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCC
MSEGIRITGRSGHSSDPDKGLNAIEIMHLVIGELKKVQQQFKEKYHNPHFDVPYPTLNFG
CCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
AISGGDSPNRICGCCELHIDMRPIPGITTSELFITVKQALSEIEKRYPKSVEIYHLHEPI
CCCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
PSYQCPAHSDLINNAEIFTGNPAQSANYCTEAPFIQQLGCDTIILGPGHISQAHQPNEYL
CCCCCCCHHHHCCCCEEEECCCCCCCCCCCCCCHHHHCCCCEEEECCCCCCCCCCCCCCE
DLSFVKPTKEVIKKLINHYCVI
EEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALPTFLNLYKDLIKIPSISSTDPSWDQSNLNVINQLASWLEELGFKSEIQAVRSAPGKY
CCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCE
NLIATLGEGDGGLLLAGHTDTVPYDAGKWTTDPFTLTEKDNRLYGLGSIDMKGFFAFVIE
EEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCHHHHHHHHHH
VLKEIDINKLNKPLRILATADEETTMAGAQEIAEQKTFRPDYAVIGEPTGMAPVTMHKGH
HHHHCCHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCC
MSEGIRITGRSGHSSDPDKGLNAIEIMHLVIGELKKVQQQFKEKYHNPHFDVPYPTLNFG
CCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
AISGGDSPNRICGCCELHIDMRPIPGITTSELFITVKQALSEIEKRYPKSVEIYHLHEPI
CCCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
PSYQCPAHSDLINNAEIFTGNPAQSANYCTEAPFIQQLGCDTIILGPGHISQAHQPNEYL
CCCCCCCHHHHCCCCEEEECCCCCCCCCCCCCCHHHHCCCCEEEECCCCCCCCCCCCCCE
DLSFVKPTKEVIKKLINHYCVI
EEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10692366 [H]