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The map label for this gene is pitA [C]

Identifier: 119943967

GI number: 119943967

Start: 228782

End: 230047

Strand: Reverse

Name: pitA [C]

Synonym: Ping_0180

Alternate gene names: 119943967

Gene position: 230047-228782 (Counterclockwise)

Preceding gene: 119943968

Following gene: 119943966

Centisome position: 5.05

GC content: 43.05

Gene sequence:

>1266_bases
ATGGATATTTTAACTTCATACGGAAGCATTCTTGTACTATTTGCGGGCGCTGTTGGTTTCCTTATGGCTTGGGGTATAGG
TGCAAACGATGTTGCCAATGCAATGGGCACCTCCGTTGGCTCAAAAGCATTAACCATCAAACAGGCAATCATTATTGCCA
TGATCTTTGAATTTGCAGGCGCTTATTTAGCGGGTGGTGAAGTAACATCAACAATACGTAAAGGTATTATCGATGCCAGC
TTCTACGTTGATCAACCCGAATTATTAGTCTTTGGTATGACGTCGGCGTTATTAGCCGCCGGTGTATGGTTAATGATTGC
CTCCTATTTTGGTTGGCCAGTTTCTACAACACACTCTATTGTTGGTGCAATCGTTGGTTTCTCTGCCGTTGGAGTAGGAG
TAGACAGCGTCGTCTGGATCAAGGTAACGGGTATTATTGGCAGTTGGGTGATAACCCCGCTGATCTCGGGTATTATTGCT
TATATGATTTTTATGAGTTCGCAAAAATTAATATTTGATACTCAAGATCCGATTAAGAATGCCAAGCGTTATGTTCCATT
TTATATGTTTCTGGCGGGTTTCCTGCTCTCTTTAGTAACTATTACTAAAGGCCTATCACATGTTGGTTTACATTTTACAA
CCTTTGAAGCGTTTGCCTTAGCCACTATTGTCGGTATCTCTGTTGCGGCGATTGGTAAAATATTTATTAACCGCATTAAA
ATCGATCCTAAAGCCGATAAAAAAATGCATTTTGCCAATGTCGAAAAAATATTTGCCGTATTGATGGTAGTGACAGCTTG
TGCAATGGCTTTTGCACATGGTTCAAACGATGTCGCCAATGCGATCGGGCCACTTGCTGCTGTTGTTAGCATTGTTGAAA
ACAACGGCCAAATAGCGGCTAAAGCGGCACTGGCGTGGTGGATATTGCCATTAGGTGGTTTAGGGATTGTACTTGGTTTA
GCTATTTTTGGTAGGCGTGTTATGGCCACCATTGGCACAGGTATTACCCACCTTACGCCAAGCCGAGGTTTTGCTGCAGA
GCTTGCAGCTGCAGCAACCGTGGTTATCGCATCGGGAACTGGTTTACCCATCTCCACAACACAAACGTTAGTAGGTGCTG
TCTTGGGCGTTGGTATGGCGCGAGGTATTGCGGCACTAAACTTAGGTGTTGTGCGTAATATAGTCATCTCATGGGTAGTA
ACCCTACCCATTGGTGCTGGTTTATCAATTATATTCTTCTATATGATGAAAGCTATTTTTAGCTAA

Upstream 100 bases:

>100_bases
CAAATTTTAGAATGGGTAGGCCGTCTTGCGGATCATTCTGAATCAATCGGTGATCAACTCGAACTTATGATTGCGCGTTC
ATAACGCTTAAAGGATTTTT

Downstream 100 bases:

>100_bases
ATAAATGATTAACACTCATGCTACCTCAGGATGAAAAATCAACATTTTAAAGTAGAATAGGTGTAGTTATTACAAAAAAA
GAGCTCTGGCTCTTTTTTTT

Product: phosphate transporter

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MDILTSYGSILVLFAGAVGFLMAWGIGANDVANAMGTSVGSKALTIKQAIIIAMIFEFAGAYLAGGEVTSTIRKGIIDAS
FYVDQPELLVFGMTSALLAAGVWLMIASYFGWPVSTTHSIVGAIVGFSAVGVGVDSVVWIKVTGIIGSWVITPLISGIIA
YMIFMSSQKLIFDTQDPIKNAKRYVPFYMFLAGFLLSLVTITKGLSHVGLHFTTFEAFALATIVGISVAAIGKIFINRIK
IDPKADKKMHFANVEKIFAVLMVVTACAMAFAHGSNDVANAIGPLAAVVSIVENNGQIAAKAALAWWILPLGGLGIVLGL
AIFGRRVMATIGTGITHLTPSRGFAAELAAAATVVIASGTGLPISTTQTLVGAVLGVGMARGIAALNLGVVRNIVISWVV
TLPIGAGLSIIFFYMMKAIFS

Sequences:

>Translated_421_residues
MDILTSYGSILVLFAGAVGFLMAWGIGANDVANAMGTSVGSKALTIKQAIIIAMIFEFAGAYLAGGEVTSTIRKGIIDAS
FYVDQPELLVFGMTSALLAAGVWLMIASYFGWPVSTTHSIVGAIVGFSAVGVGVDSVVWIKVTGIIGSWVITPLISGIIA
YMIFMSSQKLIFDTQDPIKNAKRYVPFYMFLAGFLLSLVTITKGLSHVGLHFTTFEAFALATIVGISVAAIGKIFINRIK
IDPKADKKMHFANVEKIFAVLMVVTACAMAFAHGSNDVANAIGPLAAVVSIVENNGQIAAKAALAWWILPLGGLGIVLGL
AIFGRRVMATIGTGITHLTPSRGFAAELAAAATVVIASGTGLPISTTQTLVGAVLGVGMARGIAALNLGVVRNIVISWVV
TLPIGAGLSIIFFYMMKAIFS
>Mature_421_residues
MDILTSYGSILVLFAGAVGFLMAWGIGANDVANAMGTSVGSKALTIKQAIIIAMIFEFAGAYLAGGEVTSTIRKGIIDAS
FYVDQPELLVFGMTSALLAAGVWLMIASYFGWPVSTTHSIVGAIVGFSAVGVGVDSVVWIKVTGIIGSWVITPLISGIIA
YMIFMSSQKLIFDTQDPIKNAKRYVPFYMFLAGFLLSLVTITKGLSHVGLHFTTFEAFALATIVGISVAAIGKIFINRIK
IDPKADKKMHFANVEKIFAVLMVVTACAMAFAHGSNDVANAIGPLAAVVSIVENNGQIAAKAALAWWILPLGGLGIVLGL
AIFGRRVMATIGTGITHLTPSRGFAAELAAAATVVIASGTGLPISTTQTLVGAVLGVGMARGIAALNLGVVRNIVISWVV
TLPIGAGLSIIFFYMMKAIFS

Specific function: Potential transporter for phosphate [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family [H]

Homologues:

Organism=Homo sapiens, GI5803173, Length=172, Percent_Identity=44.1860465116279, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI31543630, Length=289, Percent_Identity=35.6401384083045, Blast_Score=152, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI25146401, Length=446, Percent_Identity=35.6502242152466, Blast_Score=255, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI71981576, Length=446, Percent_Identity=36.322869955157, Blast_Score=242, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI32566716, Length=470, Percent_Identity=32.3404255319149, Blast_Score=227, Evalue=7e-60,
Organism=Caenorhabditis elegans, GI17536725, Length=474, Percent_Identity=28.0590717299578, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17539280, Length=291, Percent_Identity=33.6769759450172, Blast_Score=154, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17557328, Length=498, Percent_Identity=26.1044176706827, Blast_Score=149, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6319773, Length=162, Percent_Identity=42.5925925925926, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21356511, Length=171, Percent_Identity=44.4444444444444, Blast_Score=161, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 43901; Mature: 43901

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILTSYGSILVLFAGAVGFLMAWGIGANDVANAMGTSVGSKALTIKQAIIIAMIFEFAG
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
AYLAGGEVTSTIRKGIIDASFYVDQPELLVFGMTSALLAAGVWLMIASYFGWPVSTTHSI
CHHCCCHHHHHHHHHCCCCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VGAIVGFSAVGVGVDSVVWIKVTGIIGSWVITPLISGIIAYMIFMSSQKLIFDTQDPIKN
HHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHH
AKRYVPFYMFLAGFLLSLVTITKGLSHVGLHFTTFEAFALATIVGISVAAIGKIFINRIK
HHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IDPKADKKMHFANVEKIFAVLMVVTACAMAFAHGSNDVANAIGPLAAVVSIVENNGQIAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHH
KAALAWWILPLGGLGIVLGLAIFGRRVMATIGTGITHLTPSRGFAAELAAAATVVIASGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHEEEEECCC
GLPISTTQTLVGAVLGVGMARGIAALNLGVVRNIVISWVVTLPIGAGLSIIFFYMMKAIF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
S
C
>Mature Secondary Structure
MDILTSYGSILVLFAGAVGFLMAWGIGANDVANAMGTSVGSKALTIKQAIIIAMIFEFAG
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
AYLAGGEVTSTIRKGIIDASFYVDQPELLVFGMTSALLAAGVWLMIASYFGWPVSTTHSI
CHHCCCHHHHHHHHHCCCCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VGAIVGFSAVGVGVDSVVWIKVTGIIGSWVITPLISGIIAYMIFMSSQKLIFDTQDPIKN
HHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHH
AKRYVPFYMFLAGFLLSLVTITKGLSHVGLHFTTFEAFALATIVGISVAAIGKIFINRIK
HHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IDPKADKKMHFANVEKIFAVLMVVTACAMAFAHGSNDVANAIGPLAAVVSIVENNGQIAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHH
KAALAWWILPLGGLGIVLGLAIFGRRVMATIGTGITHLTPSRGFAAELAAAATVVIASGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHEEEEECCC
GLPISTTQTLVGAVLGVGMARGIAALNLGVVRNIVISWVVTLPIGAGLSIIFFYMMKAIF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]