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The map label for this gene is xerC

Identifier: 119943804

GI number: 119943804

Start: 16153

End: 17052

Strand: Reverse

Name: xerC

Synonym: Ping_0010

Alternate gene names: 119943804

Gene position: 17052-16153 (Counterclockwise)

Preceding gene: 119943831

Following gene: 119943803

Centisome position: 0.37

GC content: 39.44

Gene sequence:

>900_bases
ATGAGTGCTTTACAACCTCTTATCGATACCTACTTAAATCATATTGCCAGCCAGCGTGGTTTGAGCCCTGTTACCATCAC
AAACTACCAAAGTAATTTAGCTGAATTTGTTGCCCTGTTAAATGAAAATAAAGTAGGCTGTTGGACAGAGCTTGATGGAC
AATTGGTGCGCTTAATGGTTAAAACGCTGCATAAAAAGGGCCTTAAAGCCCGTTCTATTGCAACCAAACTTTCCGCTTTA
CGCTCTTTTTTAGACTATTTAGTACAGTTTGATATTTTAAGTAACAATCCGGCAAAGGGTATAGCAGCACCCAAATTAGA
TAAGCCACTGCCTAAAAATGTGTCCGTTGATGATATGTTTCAATTGCTTGATATAGATGAAAAAGATCCGCTTAGTATCC
GTGATCAGTGCATGATGGAACTGATGTACTCCTCTGGATTACGCCTTAGTGAGTTAGTTGGTATTAACTTACAAGATATA
AAGTTATCTGCAAAAGAGATAATGGTAACAGGTAAGGGAAGTAAGCAACGATTATTACCTATTACCGATAGAGCGGTTGC
GACTGTAAAAATCTGGCTTAAAATCCGTCCTGAATTTTGTATAAAGGACGAAAAAGCACTCTTTGTTTCTAAGCAAAAAA
AACGTATATCAGCGCGTAATGTACAGGCTAGAATGGAAAAATGGGGCTTAAAACAAGCCTTACCGGGCCATATAAATCCA
CATAAATTACGGCACTCTTTTGCTACCCATATGCTTGAATCAAGTGGTAACCTGCGTGCGGTGCAAACCTTGCTCGGCCA
CGCAGATTTAGCCACAACGCAGATTTATACCCACCTGGATTTTCAGCATTTATCAAAAATTTATGACCAGGCACACCCGC
GTGCTAAACGTAAAAAATAA

Upstream 100 bases:

>100_bases
TCCGGTTATAAATAAGAAAATTGATATTACCAGCAATAACGCTTTCATTATCCAATAACCAAGATGACTTAAATCTTTTT
ATTTTGGCAGGAATAAAACT

Downstream 100 bases:

>100_bases
TTACAAAATAACTACAGAAATGGATATATCACTATGAAATACTACCGGGCAATTAAACCTTTTAAAGCGATTAGTTTTGA
TCTTGATGATACGCTTTATG

Product: tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSALQPLIDTYLNHIASQRGLSPVTITNYQSNLAEFVALLNENKVGCWTELDGQLVRLMVKTLHKKGLKARSIATKLSAL
RSFLDYLVQFDILSNNPAKGIAAPKLDKPLPKNVSVDDMFQLLDIDEKDPLSIRDQCMMELMYSSGLRLSELVGINLQDI
KLSAKEIMVTGKGSKQRLLPITDRAVATVKIWLKIRPEFCIKDEKALFVSKQKKRISARNVQARMEKWGLKQALPGHINP
HKLRHSFATHMLESSGNLRAVQTLLGHADLATTQIYTHLDFQHLSKIYDQAHPRAKRKK

Sequences:

>Translated_299_residues
MSALQPLIDTYLNHIASQRGLSPVTITNYQSNLAEFVALLNENKVGCWTELDGQLVRLMVKTLHKKGLKARSIATKLSAL
RSFLDYLVQFDILSNNPAKGIAAPKLDKPLPKNVSVDDMFQLLDIDEKDPLSIRDQCMMELMYSSGLRLSELVGINLQDI
KLSAKEIMVTGKGSKQRLLPITDRAVATVKIWLKIRPEFCIKDEKALFVSKQKKRISARNVQARMEKWGLKQALPGHINP
HKLRHSFATHMLESSGNLRAVQTLLGHADLATTQIYTHLDFQHLSKIYDQAHPRAKRKK
>Mature_298_residues
SALQPLIDTYLNHIASQRGLSPVTITNYQSNLAEFVALLNENKVGCWTELDGQLVRLMVKTLHKKGLKARSIATKLSALR
SFLDYLVQFDILSNNPAKGIAAPKLDKPLPKNVSVDDMFQLLDIDEKDPLSIRDQCMMELMYSSGLRLSELVGINLQDIK
LSAKEIMVTGKGSKQRLLPITDRAVATVKIWLKIRPEFCIKDEKALFVSKQKKRISARNVQARMEKWGLKQALPGHINPH
KLRHSFATHMLESSGNLRAVQTLLGHADLATTQIYTHLDFQHLSKIYDQAHPRAKRKK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=299, Percent_Identity=55.5183946488294, Blast_Score=342, Evalue=1e-95,
Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=34.6938775510204, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1790767, Length=193, Percent_Identity=25.9067357512953, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790768, Length=159, Percent_Identity=25.1572327044025, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_PSYIN (A1SQX0)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_941484.1
- ProteinModelPortal:   A1SQX0
- SMR:   A1SQX0
- STRING:   A1SQX0
- GeneID:   4625099
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0010
- eggNOG:   COG4973
- HOGENOM:   HBG727654
- OMA:   MESNLDF
- PhylomeDB:   A1SQX0
- BioCyc:   PING357804:PING_0010-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02224

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 33783; Mature: 33652

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: ACT_SITE 148-148 ACT_SITE 172-172 ACT_SITE 241-241 ACT_SITE 244-244 ACT_SITE 267-267 ACT_SITE 276-276

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALQPLIDTYLNHIASQRGLSPVTITNYQSNLAEFVALLNENKVGCWTELDGQLVRLMV
CCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
KTLHKKGLKARSIATKLSALRSFLDYLVQFDILSNNPAKGIAAPKLDKPLPKNVSVDDMF
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHH
QLLDIDEKDPLSIRDQCMMELMYSSGLRLSELVGINLQDIKLSAKEIMVTGKGSKQRLLP
HHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCHHHHEECHHHEEEECCCCCCCCCE
ITDRAVATVKIWLKIRPEFCIKDEKALFVSKQKKRISARNVQARMEKWGLKQALPGHINP
ECCHHEEEEEEEEEECCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCH
HKLRHSFATHMLESSGNLRAVQTLLGHADLATTQIYTHLDFQHLSKIYDQAHPRAKRKK
HHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SALQPLIDTYLNHIASQRGLSPVTITNYQSNLAEFVALLNENKVGCWTELDGQLVRLMV
CHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
KTLHKKGLKARSIATKLSALRSFLDYLVQFDILSNNPAKGIAAPKLDKPLPKNVSVDDMF
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHH
QLLDIDEKDPLSIRDQCMMELMYSSGLRLSELVGINLQDIKLSAKEIMVTGKGSKQRLLP
HHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCHHHHEECHHHEEEECCCCCCCCCE
ITDRAVATVKIWLKIRPEFCIKDEKALFVSKQKKRISARNVQARMEKWGLKQALPGHINP
ECCHHEEEEEEEEEECCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCH
HKLRHSFATHMLESSGNLRAVQTLLGHADLATTQIYTHLDFQHLSKIYDQAHPRAKRKK
HHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA