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The map label for this gene is caiA [C]

Identifier: 119870810

GI number: 119870810

Start: 5013489

End: 5014442

Strand: Direct

Name: caiA [C]

Synonym: Mkms_4782

Alternate gene names: 119870810

Gene position: 5013489-5014442 (Clockwise)

Preceding gene: 119870809

Following gene: 119870811

Centisome position: 87.39

GC content: 71.17

Gene sequence:

>954_bases
GTGAACTTCGAACTCGACGATCAGCAACGCGATTTCGCCGCGAGCATCGATGCCGCGCTGGGCGCCGCCGACGTCCCCGC
CGCGGTCCGGGCGTGGTCCGAAGGTGACACCGCCCACGGCCGCAAGGTGTGGGCCACGCTCGCCGACCTCGGGGTGACCG
CGCTGATGGTCGCCGAGGAATACGACGGCATCGACGCCACGCCGGTCGACCTGGTGGTCGCCGCCGAACGGCTGGGCCGC
TGGTGTGTTCCCGGTCCGGTGGTGGAATCCGTTGCGGTGGCCCCTGTTCTGTTGCGCGGTGACGAGCGCAGCGCGGCGCT
GGCCGCAGGCGAACTGGTCGTCGCCGTCGCACTGCCCCCGCACGTGCCGCGCGCACTCGATGCCGACAGTGCCGGACTGG
TGCTGCTCGCACAGGACGGCTCGGTCAGCGAGGCCACCGCCGCCACGCAGCACGAGTCCGTGGACCCCGCGCGAAAGCTG
TTCGAGGTCACCGCATCAGGTGCCGTGCGGGAGGCGGACGTGGACCGCGCGTTCGAGTTCGGTGTGCTCGCGACCGCGGC
CCAACTCGTCGGCGCGGCGCAGGCCATGCTCGACCAGTCGGTGGACTACGCCAAACAGCGCCACCAGTTCGGCCGGGCGA
TCGGTTCGTACCAGGCGATCAAGCACAAACTGGCCGACGTGCACATCGCCGTCGAGCTGGCCCGGCCACTGGTGTACGGC
GCCGCGTTGTCGCTCGGTGACGGCTCCCCCGACACCGCCCGCGATGTCAGCGCCGCGAAGGTGGCCGCATCCGACGCCGC
GATGCTGGCGGCCCGATCGGCACTGCAGACGCACGGCGCGATCGGCTTCACCCACGAACACGACCTGTCCCTGTGGCTGC
TGCGCGTGCAGGCCCTGCGCTCTGCGTGGGGATCCCCGACGTGGCACCGCACACGGGTTCTGGAGGCCTTCTGA

Upstream 100 bases:

>100_bases
CGCTCGGCGGGCCGATCTACGCCGGCACCAACGAGATTCAGCGCAACATCATCGCCGAGCGGTTGCTGGGTCTGCCCCGT
GAGCCGAAAGGGCAAGCCAA

Downstream 100 bases:

>100_bases
TGAGCGAAGAACGCGAACTGCTGCGGGAGACCGTCGCCGCCCTGGTGGACAAGCACGCATCGCCCGCGGCCGTGCGCGAG
GCGATGACCTCCGAGCGCGG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; BCAD; SCAD [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNFELDDQQRDFAASIDAALGAADVPAAVRAWSEGDTAHGRKVWATLADLGVTALMVAEEYDGIDATPVDLVVAAERLGR
WCVPGPVVESVAVAPVLLRGDERSAALAAGELVVAVALPPHVPRALDADSAGLVLLAQDGSVSEATAATQHESVDPARKL
FEVTASGAVREADVDRAFEFGVLATAAQLVGAAQAMLDQSVDYAKQRHQFGRAIGSYQAIKHKLADVHIAVELARPLVYG
AALSLGDGSPDTARDVSAAKVAASDAAMLAARSALQTHGAIGFTHEHDLSLWLLRVQALRSAWGSPTWHRTRVLEAF

Sequences:

>Translated_317_residues
MNFELDDQQRDFAASIDAALGAADVPAAVRAWSEGDTAHGRKVWATLADLGVTALMVAEEYDGIDATPVDLVVAAERLGR
WCVPGPVVESVAVAPVLLRGDERSAALAAGELVVAVALPPHVPRALDADSAGLVLLAQDGSVSEATAATQHESVDPARKL
FEVTASGAVREADVDRAFEFGVLATAAQLVGAAQAMLDQSVDYAKQRHQFGRAIGSYQAIKHKLADVHIAVELARPLVYG
AALSLGDGSPDTARDVSAAKVAASDAAMLAARSALQTHGAIGFTHEHDLSLWLLRVQALRSAWGSPTWHRTRVLEAF
>Mature_317_residues
MNFELDDQQRDFAASIDAALGAADVPAAVRAWSEGDTAHGRKVWATLADLGVTALMVAEEYDGIDATPVDLVVAAERLGR
WCVPGPVVESVAVAPVLLRGDERSAALAAGELVVAVALPPHVPRALDADSAGLVLLAQDGSVSEATAATQHESVDPARKL
FEVTASGAVREADVDRAFEFGVLATAAQLVGAAQAMLDQSVDYAKQRHQFGRAIGSYQAIKHKLADVHIAVELARPLVYG
AALSLGDGSPDTARDVSAAKVAASDAAMLAARSALQTHGAIGFTHEHDLSLWLLRVQALRSAWGSPTWHRTRVLEAF

Specific function: Has an optimum specificity for 4-carbon length fatty acyl-CoAs [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=111, Percent_Identity=36.9369369369369, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4501859, Length=113, Percent_Identity=32.7433628318584, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17508101, Length=106, Percent_Identity=35.8490566037736, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17506239, Length=106, Percent_Identity=36.7924528301887, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17534899, Length=164, Percent_Identity=31.0975609756098, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17569725, Length=111, Percent_Identity=36.036036036036, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21356377, Length=103, Percent_Identity=38.8349514563107, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24646207, Length=109, Percent_Identity=36.697247706422, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24666513, Length=106, Percent_Identity=36.7924528301887, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 33246; Mature: 33246

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00464 RIBOSOMAL_L22

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFELDDQQRDFAASIDAALGAADVPAAVRAWSEGDTAHGRKVWATLADLGVTALMVAEE
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEHH
YDGIDATPVDLVVAAERLGRWCVPGPVVESVAVAPVLLRGDERSAALAAGELVVAVALPP
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEECCCCHHHEECCCEEEEEECCC
HVPRALDADSAGLVLLAQDGSVSEATAATQHESVDPARKLFEVTASGAVREADVDRAFEF
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
GVLATAAQLVGAAQAMLDQSVDYAKQRHQFGRAIGSYQAIKHKLADVHIAVELARPLVYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALSLGDGSPDTARDVSAAKVAASDAAMLAARSALQTHGAIGFTHEHDLSLWLLRVQALR
HHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
SAWGSPTWHRTRVLEAF
HHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNFELDDQQRDFAASIDAALGAADVPAAVRAWSEGDTAHGRKVWATLADLGVTALMVAEE
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEHH
YDGIDATPVDLVVAAERLGRWCVPGPVVESVAVAPVLLRGDERSAALAAGELVVAVALPP
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEECCCCHHHEECCCEEEEEECCC
HVPRALDADSAGLVLLAQDGSVSEATAATQHESVDPARKLFEVTASGAVREADVDRAFEF
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
GVLATAAQLVGAAQAMLDQSVDYAKQRHQFGRAIGSYQAIKHKLADVHIAVELARPLVYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALSLGDGSPDTARDVSAAKVAASDAAMLAARSALQTHGAIGFTHEHDLSLWLLRVQALR
HHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
SAWGSPTWHRTRVLEAF
HHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8399220; 7857927 [H]