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The map label for this gene is yngJ [H]

Identifier: 119870811

GI number: 119870811

Start: 5014442

End: 5015383

Strand: Direct

Name: yngJ [H]

Synonym: Mkms_4783

Alternate gene names: 119870811

Gene position: 5014442-5015383 (Clockwise)

Preceding gene: 119870810

Following gene: 119870812

Centisome position: 87.4

GC content: 71.76

Gene sequence:

>942_bases
ATGAGCGAAGAACGCGAACTGCTGCGGGAGACCGTCGCCGCCCTGGTGGACAAGCACGCATCGCCCGCGGCCGTGCGCGA
GGCGATGACCTCCGAGCGCGGCTACGACGAGTCGCTGTGGACGCTGCTGTGCGAGCAGGTCGGAGCGGCCGCGTTGGTGG
TACCTGAGGAGCTCGGCGGCGCCGGCGGCGAACTCGGGGACGCGGCAGTGGTGCTGGAGGAGCTGGGGCGCAACCTCGTC
CCGACACCGTTGCTCGGCACGACGCTGGCCGAACTGGCGCTGCTGTCGTCCGACGAACCGGACGCCGATGCGCTCGCGGG
GCTCGCCGCGGGCGAGCAGGTCGGTGCGGTCGTGTTCGACCCCGGGTACGTGGTGAACGGGGACATCGCCGACGTCGTGA
TCGGCGTCTCGGACGGGCAGCTCAGCCGCTGGACGTCGTTCGAGGCGCACCCCCTGGACGCGATGGATCTGACCCGCCGG
CTCGCCCGGGTGGAGCCGGGCGACACGGTCGCGATCGGCGCCGATCCGGGGCTGGCGGACACCGCGGCGCTGCTGACGGC
CGCCGAGCAGATCGGCGCGGCCACCCGGTGCCTGGAGCTGACCGTCGCGTACACCAAGGACCGGGTGCAGTTCGGCAGGC
CGATCGGCAGCTTCCAGGCGCTCAAGCACCGCATGGCCGACCTGTACGTCAAGGTGCAGTCCGCCAAGGCCGTCGTCGAC
GAGGCGCTGGCCGAGCCCTCCCCGGTGTCAGCGGCACTCGCCCGGTTCTCGGCGAGCGAGGCGTTCACCGCGGTGGCGGC
CGAGGCGGTGCAGATGCACGGCGGCATCGCGATCACCTGGGAAAGCGACATCCAGCTGTACTTCAAGCGGGCCCACGCCA
GTGCCCAACTGCTCGGCCCGCCCCGCGAGCAGCTTCGCCGCCTCGAGACACAAGTGTTCTAG

Upstream 100 bases:

>100_bases
ACGAACACGACCTGTCCCTGTGGCTGCTGCGCGTGCAGGCCCTGCGCTCTGCGTGGGGATCCCCGACGTGGCACCGCACA
CGGGTTCTGGAGGCCTTCTG

Downstream 100 bases:

>100_bases
CCTCGATCTGATGAGCGGAGCCCACGCACAACGCACCGAGCCGCGGGACGTGGCCCTACGCGCCGGCATCCCGCCGTTCT
ACGTGATGGACGTCTGGCTG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSEERELLRETVAALVDKHASPAAVREAMTSERGYDESLWTLLCEQVGAAALVVPEELGGAGGELGDAAVVLEELGRNLV
PTPLLGTTLAELALLSSDEPDADALAGLAAGEQVGAVVFDPGYVVNGDIADVVIGVSDGQLSRWTSFEAHPLDAMDLTRR
LARVEPGDTVAIGADPGLADTAALLTAAEQIGAATRCLELTVAYTKDRVQFGRPIGSFQALKHRMADLYVKVQSAKAVVD
EALAEPSPVSAALARFSASEAFTAVAAEAVQMHGGIAITWESDIQLYFKRAHASAQLLGPPREQLRRLETQVF

Sequences:

>Translated_313_residues
MSEERELLRETVAALVDKHASPAAVREAMTSERGYDESLWTLLCEQVGAAALVVPEELGGAGGELGDAAVVLEELGRNLV
PTPLLGTTLAELALLSSDEPDADALAGLAAGEQVGAVVFDPGYVVNGDIADVVIGVSDGQLSRWTSFEAHPLDAMDLTRR
LARVEPGDTVAIGADPGLADTAALLTAAEQIGAATRCLELTVAYTKDRVQFGRPIGSFQALKHRMADLYVKVQSAKAVVD
EALAEPSPVSAALARFSASEAFTAVAAEAVQMHGGIAITWESDIQLYFKRAHASAQLLGPPREQLRRLETQVF
>Mature_312_residues
SEERELLRETVAALVDKHASPAAVREAMTSERGYDESLWTLLCEQVGAAALVVPEELGGAGGELGDAAVVLEELGRNLVP
TPLLGTTLAELALLSSDEPDADALAGLAAGEQVGAVVFDPGYVVNGDIADVVIGVSDGQLSRWTSFEAHPLDAMDLTRRL
ARVEPGDTVAIGADPGLADTAALLTAAEQIGAATRCLELTVAYTKDRVQFGRPIGSFQALKHRMADLYVKVQSAKAVVDE
ALAEPSPVSAALARFSASEAFTAVAAEAVQMHGGIAITWESDIQLYFKRAHASAQLLGPPREQLRRLETQVF

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=157, Percent_Identity=24.8407643312102, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 32970; Mature: 32838

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEERELLRETVAALVDKHASPAAVREAMTSERGYDESLWTLLCEQVGAAALVVPEELGG
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEECHHHCC
AGGELGDAAVVLEELGRNLVPTPLLGTTLAELALLSSDEPDADALAGLAAGEQVGAVVFD
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEC
PGYVVNGDIADVVIGVSDGQLSRWTSFEAHPLDAMDLTRRLARVEPGDTVAIGADPGLAD
CCEEECCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHH
TAALLTAAEQIGAATRCLELTVAYTKDRVQFGRPIGSFQALKHRMADLYVKVQSAKAVVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EALAEPSPVSAALARFSASEAFTAVAAEAVQMHGGIAITWESDIQLYFKRAHASAQLLGP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCHHHCCC
PREQLRRLETQVF
CHHHHHHHHHHCC
>Mature Secondary Structure 
SEERELLRETVAALVDKHASPAAVREAMTSERGYDESLWTLLCEQVGAAALVVPEELGG
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEECHHHCC
AGGELGDAAVVLEELGRNLVPTPLLGTTLAELALLSSDEPDADALAGLAAGEQVGAVVFD
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEC
PGYVVNGDIADVVIGVSDGQLSRWTSFEAHPLDAMDLTRRLARVEPGDTVAIGADPGLAD
CCEEECCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHH
TAALLTAAEQIGAATRCLELTVAYTKDRVQFGRPIGSFQALKHRMADLYVKVQSAKAVVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EALAEPSPVSAALARFSASEAFTAVAAEAVQMHGGIAITWESDIQLYFKRAHASAQLLGP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCHHHCCC
PREQLRRLETQVF
CHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]