| Definition | Mycobacterium sp. KMS chromosome, complete genome. |
|---|---|
| Accession | NC_008705 |
| Length | 5,737,227 |
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The map label for this gene is ucpA [C]
Identifier: 119869902
GI number: 119869902
Start: 4085955
End: 4086695
Strand: Direct
Name: ucpA [C]
Synonym: Mkms_3871
Alternate gene names: 119869902
Gene position: 4085955-4086695 (Clockwise)
Preceding gene: 119869901
Following gene: 119869926
Centisome position: 71.22
GC content: 69.64
Gene sequence:
>741_bases GTGAGTCTCGCCGGGAAGGTCGCCTTCGTCGCCGGCGCCAGCCGTGGCATCGGCGCGACGGTGGCGAAAGCCCTCGCCGC AGAAGGCGCTGCCGTGGCAGTCGCCGCCCGGTCCGAGCAGCCGGGCAAGTTACCGGGGACCATCCATACGGTGGCCGAGT CCATCACCGCGTCCGGCGGCCGTGCGCTACCGGTGTCGTGTGACGTCACCGATGAATCGTCAGTGGAAACCGCAGTGGCC GAGACCGTTTCGGAATTCGGCGGAATCGACATCCTGGTCGCGAACGCCGGGGTGCTGTGGCTCGGCCCGATCGAGTCGAC GCCGCTGAAGCGTTGGCAGCTGTGCCTGAACGTCAACCTCACCGGCGTGTTCCTCGTGACGAAGGCAGTCATCCCCCACG TGCGCGCGCGTGGCGGCGGATCCCTGATCGCGGTGACGACCACCGGCGTGACCATGACCGACCAGGGTTCGAACGCGTAC TGGGTGTCCAAGGCCGCCGCCGAACGGCTCTACCTCGGGTTGGCGGCCGACCTGCGGGCCGACAACATCGCGGTGAACTG CCTGAGCCCCTCGCGCGTCGTGCTCACCGAGGGCTGGCAGGCCGGCGGCGCGGGCATGGAGATCCCACCGGAGATGGTCG AGCCCCCGGAGGCCATGGGGCGCGCGGCCGTGCTGCTGGCGGCACAGGACGCCAGCGGGATCACCGGAACGATCCAACGC TCCGAAGAGGTTGTGCGCTAG
Upstream 100 bases:
>100_bases GCTCGACGGAGTACGCGCAACTGGCGCAGAGCATCATCGAGAACGACTACCTCAACGGTGAGATCATCCGCCTCGACGGA GCGCTTCGGTTCCCGCCCAA
Downstream 100 bases:
>100_bases TCGGATTCGTCGTCGCCCTCCGACTTGTCGGTGAGGTAGCGGTGGGGGTGGAAGTGGTTGTTGATGCGGGGTTGGCCGGT GTCGTGGTCTTCGGGTGGGG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: ORFC [H]
Number of amino acids: Translated: 246; Mature: 245
Protein sequence:
>246_residues MSLAGKVAFVAGASRGIGATVAKALAAEGAAVAVAARSEQPGKLPGTIHTVAESITASGGRALPVSCDVTDESSVETAVA ETVSEFGGIDILVANAGVLWLGPIESTPLKRWQLCLNVNLTGVFLVTKAVIPHVRARGGGSLIAVTTTGVTMTDQGSNAY WVSKAAAERLYLGLAADLRADNIAVNCLSPSRVVLTEGWQAGGAGMEIPPEMVEPPEAMGRAAVLLAAQDASGITGTIQR SEEVVR
Sequences:
>Translated_246_residues MSLAGKVAFVAGASRGIGATVAKALAAEGAAVAVAARSEQPGKLPGTIHTVAESITASGGRALPVSCDVTDESSVETAVA ETVSEFGGIDILVANAGVLWLGPIESTPLKRWQLCLNVNLTGVFLVTKAVIPHVRARGGGSLIAVTTTGVTMTDQGSNAY WVSKAAAERLYLGLAADLRADNIAVNCLSPSRVVLTEGWQAGGAGMEIPPEMVEPPEAMGRAAVLLAAQDASGITGTIQR SEEVVR >Mature_245_residues SLAGKVAFVAGASRGIGATVAKALAAEGAAVAVAARSEQPGKLPGTIHTVAESITASGGRALPVSCDVTDESSVETAVAE TVSEFGGIDILVANAGVLWLGPIESTPLKRWQLCLNVNLTGVFLVTKAVIPHVRARGGGSLIAVTTTGVTMTDQGSNAYW VSKAAAERLYLGLAADLRADNIAVNCLSPSRVVLTEGWQAGGAGMEIPPEMVEPPEAMGRAAVLLAAQDASGITGTIQRS EEVVR
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254986, Length=210, Percent_Identity=39.0476190476191, Blast_Score=134, Evalue=8e-32, Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=33.8775510204082, Blast_Score=107, Evalue=8e-24, Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=35.7894736842105, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=30.6772908366534, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=27.8225806451613, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=28.4263959390863, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=31.7708333333333, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI5031737, Length=192, Percent_Identity=31.7708333333333, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI59889578, Length=195, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI7706318, Length=176, Percent_Identity=30.1136363636364, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI109715829, Length=193, Percent_Identity=27.979274611399, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI40254992, Length=189, Percent_Identity=30.6878306878307, Blast_Score=68, Evalue=6e-12, Organism=Homo sapiens, GI4504505, Length=197, Percent_Identity=28.9340101522843, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI209862901, Length=212, Percent_Identity=30.188679245283, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI19923983, Length=212, Percent_Identity=30.188679245283, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI302344755, Length=107, Percent_Identity=40.1869158878505, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI31542939, Length=141, Percent_Identity=31.9148936170213, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI224922801, Length=141, Percent_Identity=31.9148936170213, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI7657478, Length=201, Percent_Identity=29.3532338308458, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=32.03125, Blast_Score=101, Evalue=4e-23, Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=29.7520661157025, Blast_Score=93, Evalue=1e-20, Organism=Escherichia coli, GI1790717, Length=190, Percent_Identity=30, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=30.7086614173228, Blast_Score=83, Evalue=1e-17, Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=29.6747967479675, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1789208, Length=194, Percent_Identity=31.4432989690722, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1787820, Length=193, Percent_Identity=26.9430051813472, Blast_Score=71, Evalue=6e-14, Organism=Escherichia coli, GI87082160, Length=190, Percent_Identity=27.3684210526316, Blast_Score=65, Evalue=3e-12, Organism=Escherichia coli, GI1786812, Length=190, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=3e-12, Organism=Escherichia coli, GI1788459, Length=186, Percent_Identity=25.8064516129032, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71982365, Length=254, Percent_Identity=35.0393700787402, Blast_Score=140, Evalue=5e-34, Organism=Caenorhabditis elegans, GI17558628, Length=249, Percent_Identity=34.5381526104418, Blast_Score=120, Evalue=6e-28, Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=29.4820717131474, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17538480, Length=252, Percent_Identity=28.1746031746032, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=29.0322580645161, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17560332, Length=256, Percent_Identity=28.90625, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17544670, Length=208, Percent_Identity=28.3653846153846, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17562906, Length=222, Percent_Identity=28.8288288288288, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17562904, Length=196, Percent_Identity=31.1224489795918, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17551412, Length=253, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17559104, Length=217, Percent_Identity=29.9539170506912, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17568967, Length=228, Percent_Identity=31.140350877193, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=25.7028112449799, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17565030, Length=214, Percent_Identity=29.9065420560748, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=24.390243902439, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17562910, Length=196, Percent_Identity=28.0612244897959, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17560150, Length=199, Percent_Identity=29.1457286432161, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17555612, Length=203, Percent_Identity=31.0344827586207, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17562908, Length=230, Percent_Identity=28.2608695652174, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=222, Percent_Identity=27.027027027027, Blast_Score=70, Evalue=3e-13, Organism=Saccharomyces cerevisiae, GI6322227, Length=196, Percent_Identity=26.530612244898, Blast_Score=65, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322226, Length=180, Percent_Identity=30, Blast_Score=64, Evalue=2e-11, Organism=Drosophila melanogaster, GI21357673, Length=251, Percent_Identity=34.6613545816733, Blast_Score=139, Evalue=2e-33, Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=33.0645161290323, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=32.6612903225806, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI23397609, Length=194, Percent_Identity=35.5670103092784, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=29.8387096774194, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=29.7520661157025, Blast_Score=91, Evalue=6e-19, Organism=Drosophila melanogaster, GI24643142, Length=199, Percent_Identity=33.6683417085427, Blast_Score=78, Evalue=4e-15, Organism=Drosophila melanogaster, GI28571387, Length=171, Percent_Identity=35.0877192982456, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI18859837, Length=220, Percent_Identity=28.1818181818182, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=27.2251308900524, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24639444, Length=194, Percent_Identity=29.3814432989691, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI116007234, Length=196, Percent_Identity=32.1428571428571, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 25001; Mature: 24870
Theoretical pI: Translated: 4.87; Mature: 4.87
Prosite motif: PS00599 AA_TRANSFER_CLASS_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSLAGKVAFVAGASRGIGATVAKALAAEGAAVAVAARSEQPGKLPGTIHTVAESITASGG CCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCC RALPVSCDVTDESSVETAVAETVSEFGGIDILVANAGVLWLGPIESTPLKRWQLCLNVNL EEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEECCCEEEECCCCCCCCCEEEEEEECCC TGVFLVTKAVIPHVRARGGGSLIAVTTTGVTMTDQGSNAYWVSKAAAERLYLGLAADLRA HHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEECCCCCEEEEEHHHHHHEEEEEECCCCC DNIAVNCLSPSRVVLTEGWQAGGAGMEIPPEMVEPPEAMGRAAVLLAAQDASGITGTIQR CCEEEEECCCCEEEEECCCCCCCCCCCCCHHHCCCHHHHCCEEEEEEECCCCCCEEEEEC SEEVVR CHHHCC >Mature Secondary Structure SLAGKVAFVAGASRGIGATVAKALAAEGAAVAVAARSEQPGKLPGTIHTVAESITASGG CCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCC RALPVSCDVTDESSVETAVAETVSEFGGIDILVANAGVLWLGPIESTPLKRWQLCLNVNL EEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEECCCEEEECCCCCCCCCEEEEEEECCC TGVFLVTKAVIPHVRARGGGSLIAVTTTGVTMTDQGSNAYWVSKAAAERLYLGLAADLRA HHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEECCCCCEEEEEHHHHHHEEEEEECCCCC DNIAVNCLSPSRVVLTEGWQAGGAGMEIPPEMVEPPEAMGRAAVLLAAQDASGITGTIQR CCEEEEECCCCEEEEECCCCCCCCCCCCCHHHCCCHHHHCCEEEEEEECCCCCCEEEEEC SEEVVR CHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8868443 [H]