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The map label for this gene is hmp [H]

Identifier: 119869926

GI number: 119869926

Start: 4102891

End: 4103208

Strand: Direct

Name: hmp [H]

Synonym: Mkms_3896

Alternate gene names: 119869926

Gene position: 4102891-4103208 (Clockwise)

Preceding gene: 119869902

Following gene: 119869931

Centisome position: 71.51

GC content: 69.81

Gene sequence:

>318_bases
ATGACGGCCGATCCGATGCCCGCGGTGCCCGACGGCGGGGCCGGCACCGAGGTCACCATCGTGCTCGACCGCAAGACGCT
GTCGGTGGCCCAGGTGCCCGGCGAAACACTGCTCGAGAGCGCACGCAGGGCCGGTATGTCGCCGCCGTTCTCCTGCGAGG
CCGGCAACTGCGGGACCTGCATCGCCAAGCTCACCGAGGGCACCGCCACCATGCGGGTCAACGACGCGCTCGACGACGAC
GAGGTGGCGGACGGATACGTGCTGACCTGCCAGGCGGTTCCGGACACCGCCAGAGTGTCGGTCACCTACGACGACTGA

Upstream 100 bases:

>100_bases
GGACCCTCCTGGACGCCGTACATTGCACTTGAGAACAGCCTATCATTTCGGGAGAATAGAGTTCTCCATATATCAGAACC
ACCATGCTCGAAGGAGTCAC

Downstream 100 bases:

>100_bases
CCGGTGGCCGCCTCCGGAAGTTGTGGCGGCGGGCGGTAATCGGGTCGGTAACCGGCGATGCGGATGGGGCTGCCGACCAA
CCGGAAGTCACCGGCGGTCA

Product: ferredoxin

Products: NA

Alternate protein names: Rieske-type oxygenase; RO [H]

Number of amino acids: Translated: 105; Mature: 104

Protein sequence:

>105_residues
MTADPMPAVPDGGAGTEVTIVLDRKTLSVAQVPGETLLESARRAGMSPPFSCEAGNCGTCIAKLTEGTATMRVNDALDDD
EVADGYVLTCQAVPDTARVSVTYDD

Sequences:

>Translated_105_residues
MTADPMPAVPDGGAGTEVTIVLDRKTLSVAQVPGETLLESARRAGMSPPFSCEAGNCGTCIAKLTEGTATMRVNDALDDD
EVADGYVLTCQAVPDTARVSVTYDD
>Mature_104_residues
TADPMPAVPDGGAGTEVTIVLDRKTLSVAQVPGETLLESARRAGMSPPFSCEAGNCGTCIAKLTEGTATMRVNDALDDDE
VADGYVLTCQAVPDTARVSVTYDD

Specific function: Catalyzes the opening of ring B of 1,4-androstadiene- 3,17,-dione (ADD) and 4-androstene-3,17-dione (ADD) with concomitant aromatization of ring A. The ring B is subsequently hydroxylated to yield a catechol and then subject to meta- cleavage [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787658, Length=91, Percent_Identity=40.6593406593407, Blast_Score=69, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 10866; Mature: 10735

Theoretical pI: Translated: 3.85; Mature: 3.85

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADPMPAVPDGGAGTEVTIVLDRKTLSVAQVPGETLLESARRAGMSPPFSCEAGNCGTC
CCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCE
IAKLTEGTATMRVNDALDDDEVADGYVLTCQAVPDTARVSVTYDD
EEEECCCCEEEEECCCCCCCCCCCCEEEEEEECCCCEEEEEEECC
>Mature Secondary Structure 
TADPMPAVPDGGAGTEVTIVLDRKTLSVAQVPGETLLESARRAGMSPPFSCEAGNCGTC
CCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCE
IAKLTEGTATMRVNDALDDDEVADGYVLTCQAVPDTARVSVTYDD
EEEECCCCEEEEECCCCCCCCCCCCEEEEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FAD [C]

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]