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The map label for this gene is bcd [H]

Identifier: 119868695

GI number: 119868695

Start: 2794692

End: 2796527

Strand: Direct

Name: bcd [H]

Synonym: Mkms_2662

Alternate gene names: 119868695

Gene position: 2794692-2796527 (Clockwise)

Preceding gene: 119868694

Following gene: 119868696

Centisome position: 48.71

GC content: 63.67

Gene sequence:

>1836_bases
ATGACACACTTCCGCCCCAACGTCCGAGATATCGAGTTCAACCTTTTCGAGGTCCTCGGTGTTGACCGACTGCTCGACGA
CGGCTGTTACGGCGATCTCGACACCGAGACGGTGCGCCACATCTTCGAAGAGGTTGTCCGCCTTGCCGAAGGCCCACTGG
CCGAATCCTACGTGCAGGCCGACCGACACCCGATCCGGTTCGACGCCGCCTCCCACGAGGTCGTCGTCACCGATCCGCTG
CGCAAATCGGTTCTCGCACTCAAAGAGGCAGGCTGGTGGCGGCTGGGTATTCCCGAGGACATCGGGGGCACGCTCGCGCC
GATGCCGATGGTGTGGGCGGTCCGGGAGATCCTGCACTCAGCCAACCTGTCCGCGGCCTTCTTCAACCTCGGGCCGGAGA
TGGCGGCCGCCCTGTGGGAGGTCGGCACGCCCGAACAACGGCGTTGGGCCGCCGTCGCCATGGAGCGGGGTTGGGCGGGA
ACCATGGTGCTCACGGAACCGGACGCCGGCTCCGACGTCGGCGCCGGGGTCACCAAAGCAGTCGAACAGTCGGACGGGAC
CTGGCACATCACCGGCGTCAAACGCTTCATCTCCGGCGGCGACGTAGGTGACACCGCGGAGAACATCTTCCACCTCGTCC
TGGCCCGGCCCCAAGGAGCCGGCCCAGGGACCAAGGGACTGAGCATGTTCTTCGTCCCGAAGCATCTGTTCGACCCCGCG
ACGATGCAGATCACCTCCCGCAACGGTGTTTACGTCACCGGGGTCGAGCACAAAATGGGCATCAAGTCTTCCCCAACCTG
CGAGATCACCTTCGGCAGAGACCAACCCGCGATCGGCTGGTTGGTGGGCGATGTCCACAACGGTATCGCCCAGATGTTCA
AGGTGATGGAGAACGCACGGATGGGCACCGGCGTGATGTCGACGGGGATGCTGTCGACCGGCTACCTCAGCGCACTCGAC
TACGCCAAGACGCGCATTCAGGGACCTGATCTGACCCGCACCTCCGACAAGACCGCGCCCCGGGTACCGATCATCCGCCA
TCCGGAAGTACGGCGCTCGCTGTTAACGCAGAAGTCCTATGCCGAAGGGCTGCGGGCGCTGTACCTGTTCACCGCCGTCC
ACCAGGACGCCGTTCCTCAGCTGGCCCGCAGCGTGTCGCACGCCGAACCGGAGCTCGCCGCCAAGATCAACGACCTGCTG
CTACCCGTCGTCAAAGCGGTCAGTTCAGAACGGGCTTACGACACACTCAAACTCAGCCTGCAGATGTTCGGCGGATCTGG
TTACCTCCAGGACTATCCGATGGAGCAGTATGTCAGGGACTGCCTGATCAACACCCTGTACGAGGGGACCACCGCCATTC
AGGCACAGGACTTGTTGTTTCGCAAAATCATCCGGGACGACGGGCAGACCCTCGACCATGTACTGGGGCTCATCGTCAAG
TTCACCGAATCCGCGGGCGGCTCAACGTTCCAGCAGGAGCGAGCGCTGCTGGCGACTGCGATAGAGGACATCCGATCGAT
GGTCCACACGCTGCGCGGGCACTTCGACGCGGCGCGTGAGGAGCCCACCGAGGTGTACAGAACGGGTTTGGGATCGGTGC
CCTTGCTCTTCGCGCTCGGCGATCTCGTGATCGGCTGGCTGCTGCTATGGCAGGCGAAGGTGGCCAACGACGCGCTGTTG
CAAGCGCACTCAGACCAGGGCCGACAGTTCTACAACGGCAAGATCACCTCGGCACGGTTCTTCGCTCGCACAGCACTGCC
CGGCATATCGGCGATCCGCGCTGCGGTCGAGGCGGAGGACTACGGCGTGATGGAGTTGGCCGAAGAAGCCTTCTGA

Upstream 100 bases:

>100_bases
GGTCGAGCGAATCTGCCCCACGACACGTGCAGCGAGCGCGTCGCCACACTGGCCCTCTGATGCGGCCAGCCCCTTTGATT
GGTCAACAGAAAGCGCGCAG

Downstream 100 bases:

>100_bases
TCGATCAACGAGGCGATGACGCCGTCGGCTTCTCTGACCTGAGACCTGCAAGCGATAGTCCCAGAAGGCCTCCCCCAGCC
ACATTTCAGTGATGCACTGC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 611; Mature: 610

Protein sequence:

>611_residues
MTHFRPNVRDIEFNLFEVLGVDRLLDDGCYGDLDTETVRHIFEEVVRLAEGPLAESYVQADRHPIRFDAASHEVVVTDPL
RKSVLALKEAGWWRLGIPEDIGGTLAPMPMVWAVREILHSANLSAAFFNLGPEMAAALWEVGTPEQRRWAAVAMERGWAG
TMVLTEPDAGSDVGAGVTKAVEQSDGTWHITGVKRFISGGDVGDTAENIFHLVLARPQGAGPGTKGLSMFFVPKHLFDPA
TMQITSRNGVYVTGVEHKMGIKSSPTCEITFGRDQPAIGWLVGDVHNGIAQMFKVMENARMGTGVMSTGMLSTGYLSALD
YAKTRIQGPDLTRTSDKTAPRVPIIRHPEVRRSLLTQKSYAEGLRALYLFTAVHQDAVPQLARSVSHAEPELAAKINDLL
LPVVKAVSSERAYDTLKLSLQMFGGSGYLQDYPMEQYVRDCLINTLYEGTTAIQAQDLLFRKIIRDDGQTLDHVLGLIVK
FTESAGGSTFQQERALLATAIEDIRSMVHTLRGHFDAAREEPTEVYRTGLGSVPLLFALGDLVIGWLLLWQAKVANDALL
QAHSDQGRQFYNGKITSARFFARTALPGISAIRAAVEAEDYGVMELAEEAF

Sequences:

>Translated_611_residues
MTHFRPNVRDIEFNLFEVLGVDRLLDDGCYGDLDTETVRHIFEEVVRLAEGPLAESYVQADRHPIRFDAASHEVVVTDPL
RKSVLALKEAGWWRLGIPEDIGGTLAPMPMVWAVREILHSANLSAAFFNLGPEMAAALWEVGTPEQRRWAAVAMERGWAG
TMVLTEPDAGSDVGAGVTKAVEQSDGTWHITGVKRFISGGDVGDTAENIFHLVLARPQGAGPGTKGLSMFFVPKHLFDPA
TMQITSRNGVYVTGVEHKMGIKSSPTCEITFGRDQPAIGWLVGDVHNGIAQMFKVMENARMGTGVMSTGMLSTGYLSALD
YAKTRIQGPDLTRTSDKTAPRVPIIRHPEVRRSLLTQKSYAEGLRALYLFTAVHQDAVPQLARSVSHAEPELAAKINDLL
LPVVKAVSSERAYDTLKLSLQMFGGSGYLQDYPMEQYVRDCLINTLYEGTTAIQAQDLLFRKIIRDDGQTLDHVLGLIVK
FTESAGGSTFQQERALLATAIEDIRSMVHTLRGHFDAAREEPTEVYRTGLGSVPLLFALGDLVIGWLLLWQAKVANDALL
QAHSDQGRQFYNGKITSARFFARTALPGISAIRAAVEAEDYGVMELAEEAF
>Mature_610_residues
THFRPNVRDIEFNLFEVLGVDRLLDDGCYGDLDTETVRHIFEEVVRLAEGPLAESYVQADRHPIRFDAASHEVVVTDPLR
KSVLALKEAGWWRLGIPEDIGGTLAPMPMVWAVREILHSANLSAAFFNLGPEMAAALWEVGTPEQRRWAAVAMERGWAGT
MVLTEPDAGSDVGAGVTKAVEQSDGTWHITGVKRFISGGDVGDTAENIFHLVLARPQGAGPGTKGLSMFFVPKHLFDPAT
MQITSRNGVYVTGVEHKMGIKSSPTCEITFGRDQPAIGWLVGDVHNGIAQMFKVMENARMGTGVMSTGMLSTGYLSALDY
AKTRIQGPDLTRTSDKTAPRVPIIRHPEVRRSLLTQKSYAEGLRALYLFTAVHQDAVPQLARSVSHAEPELAAKINDLLL
PVVKAVSSERAYDTLKLSLQMFGGSGYLQDYPMEQYVRDCLINTLYEGTTAIQAQDLLFRKIIRDDGQTLDHVLGLIVKF
TESAGGSTFQQERALLATAIEDIRSMVHTLRGHFDAAREEPTEVYRTGLGSVPLLFALGDLVIGWLLLWQAKVANDALLQ
AHSDQGRQFYNGKITSARFFARTALPGISAIRAAVEAEDYGVMELAEEAF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=377, Percent_Identity=26.2599469496021, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI87082384, Length=305, Percent_Identity=27.8688524590164, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87081958, Length=390, Percent_Identity=24.8717948717949, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17533517, Length=418, Percent_Identity=24.6411483253589, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI86563383, Length=357, Percent_Identity=24.9299719887955, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI86563381, Length=357, Percent_Identity=24.9299719887955, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71985184, Length=313, Percent_Identity=23.961661341853, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17569725, Length=361, Percent_Identity=26.5927977839335, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24666513, Length=394, Percent_Identity=25.8883248730964, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21356377, Length=381, Percent_Identity=25.1968503937008, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 67083; Mature: 66952

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHFRPNVRDIEFNLFEVLGVDRLLDDGCYGDLDTETVRHIFEEVVRLAEGPLAESYVQA
CCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHC
DRHPIRFDAASHEVVVTDPLRKSVLALKEAGWWRLGIPEDIGGTLAPMPMVWAVREILHS
CCCCEEEECCCCCEEEECHHHHHHHHHHHCCCEECCCCHHCCCCCCCHHHHHHHHHHHHH
ANLSAAFFNLGPEMAAALWEVGTPEQRRWAAVAMERGWAGTMVLTEPDAGSDVGAGVTKA
CCCCHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHH
VEQSDGTWHITGVKRFISGGDVGDTAENIFHLVLARPQGAGPGTKGLSMFFVPKHLFDPA
HHCCCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHCCCC
TMQITSRNGVYVTGVEHKMGIKSSPTCEITFGRDQPAIGWLVGDVHNGIAQMFKVMENAR
EEEEECCCCEEEEECHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCC
MGTGVMSTGMLSTGYLSALDYAKTRIQGPDLTRTSDKTAPRVPIIRHPEVRRSLLTQKSY
CCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AEGLRALYLFTAVHQDAVPQLARSVSHAEPELAAKINDLLLPVVKAVSSERAYDTLKLSL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
QMFGGSGYLQDYPMEQYVRDCLINTLYEGTTAIQAQDLLFRKIIRDDGQTLDHVLGLIVK
EEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FTESAGGSTFQQERALLATAIEDIRSMVHTLRGHFDAAREEPTEVYRTGLGSVPLLFALG
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHH
DLVIGWLLLWQAKVANDALLQAHSDQGRQFYNGKITSARFFARTALPGISAIRAAVEAED
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHCC
YGVMELAEEAF
CCHHHHHHHCC
>Mature Secondary Structure 
THFRPNVRDIEFNLFEVLGVDRLLDDGCYGDLDTETVRHIFEEVVRLAEGPLAESYVQA
CCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHC
DRHPIRFDAASHEVVVTDPLRKSVLALKEAGWWRLGIPEDIGGTLAPMPMVWAVREILHS
CCCCEEEECCCCCEEEECHHHHHHHHHHHCCCEECCCCHHCCCCCCCHHHHHHHHHHHHH
ANLSAAFFNLGPEMAAALWEVGTPEQRRWAAVAMERGWAGTMVLTEPDAGSDVGAGVTKA
CCCCHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHH
VEQSDGTWHITGVKRFISGGDVGDTAENIFHLVLARPQGAGPGTKGLSMFFVPKHLFDPA
HHCCCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHCCCC
TMQITSRNGVYVTGVEHKMGIKSSPTCEITFGRDQPAIGWLVGDVHNGIAQMFKVMENAR
EEEEECCCCEEEEECHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCC
MGTGVMSTGMLSTGYLSALDYAKTRIQGPDLTRTSDKTAPRVPIIRHPEVRRSLLTQKSY
CCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AEGLRALYLFTAVHQDAVPQLARSVSHAEPELAAKINDLLLPVVKAVSSERAYDTLKLSL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
QMFGGSGYLQDYPMEQYVRDCLINTLYEGTTAIQAQDLLFRKIIRDDGQTLDHVLGLIVK
EEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FTESAGGSTFQQERALLATAIEDIRSMVHTLRGHFDAAREEPTEVYRTGLGSVPLLFALG
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHH
DLVIGWLLLWQAKVANDALLQAHSDQGRQFYNGKITSARFFARTALPGISAIRAAVEAED
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHCC
YGVMELAEEAF
CCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]