BacMap

Definition	Mycobacterium sp. KMS chromosome, complete genome.
Accession	NC_008705
Length	5,737,227

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The map label for this gene is yusZ [H]

Identifier: 119868696

GI number: 119868696

Start: 2797132

End: 2798004

Strand: Direct

Name: yusZ [H]

Synonym: Mkms_2663

Alternate gene names: 119868696

Gene position: 2797132-2798004 (Clockwise)

Preceding gene: 119868695

Following gene: 119868697

Centisome position: 48.75

GC content: 68.04

Gene sequence:

>873_bases
ATGACAACAGCTACGGCATCGCAGACCTGGATCATCACCGGAGCCTCGAAGGGACTCGGACGTGCACTGGCCGAGGCCGC
CCTTGCCGCGGGCGATCAGGTCGTGGCCGCAGTCCGCAATCCTGACGCTATGGCCGACCTGATCACCAACTTCGGTGACC
GCGTCACAAGTGTCCAGTTCGATGCCCGAGACACCACCAAAGCCGCCGGCCTCGTCCAGGCTGCGGTCGAGCGTTACGGC
CGGCTCGACGTCCTGGTGAACAACGCCGGACGCGCCATCGTCGGCGCCGCTGAGGAAGTCACCGACGCGCAGCTGCGCGA
CCTGATGGACCTGCACTTCTTCGGTCCCGCCGCCCTCGTCCGTGCGGCACTACCGATCATGCGGGCTCAGGGCGGCGGGA
CGATCGTGCAGATGAGCAGCCAGGGCGGCCGGACGTCCTTCCCCGGCGTCTCCGCTTACTCGGCGTCGAAGTTCGCGTTG
GAGGGATGGTCAGAGGCCTTGGCCGGCGAAGTCGCCCGGTTCGGGATCGGTGTGATGCTGGTCGAGCCCAGCCGGTTCCG
CACCGCGTTCAACACCGCCGACGTGCTCGACTTCACCGCCGTCTCGCCGACCTACCGGGAGATCCTGGCCGATGTGCGCG
CCGACATGGCCGGCGCGGACGGGAACCAGGAAGGTGACCCCGTCAAGGCCGCTCAGATCATCGTCTCCTTGGCCCATTCC
GAGGAAGTGCCGCTGCGGCTGCCGCTGGGCGCCGAGGCCGTCGAGCGGCTCACCGCAGCCTATCGACGCAGTCTGGAGGA
GGTCAGCCAGTGGGCTGAGCTTGCGCGCAGCGCCGACTTCGCCGACGTCCCCGCCTCAATGCGTCCGATCTAG

Upstream 100 bases:

>100_bases
GTGCGGACCCCCGCCCCGCTGCGGATCGACGGGCCGCCTTCGCGACCCTGCTGGGGTCGAGCTTGCGTTCGAGCGCGCTC
GAACTCCTAACGTCACGGCC

Downstream 100 bases:

>100_bases
GATCGGGTATGTCCACCGACGACCTGATGACCAAGGCCCTCGCCTCACTCGGCGAGATCGACGGTCCGATGTCGATCGAG
GTGATCCATCGCCTCGCCGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: ORFA [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MTTATASQTWIITGASKGLGRALAEAALAAGDQVVAAVRNPDAMADLITNFGDRVTSVQFDARDTTKAAGLVQAAVERYG
RLDVLVNNAGRAIVGAAEEVTDAQLRDLMDLHFFGPAALVRAALPIMRAQGGGTIVQMSSQGGRTSFPGVSAYSASKFAL
EGWSEALAGEVARFGIGVMLVEPSRFRTAFNTADVLDFTAVSPTYREILADVRADMAGADGNQEGDPVKAAQIIVSLAHS
EEVPLRLPLGAEAVERLTAAYRRSLEEVSQWAELARSADFADVPASMRPI

Sequences:

>Translated_290_residues
MTTATASQTWIITGASKGLGRALAEAALAAGDQVVAAVRNPDAMADLITNFGDRVTSVQFDARDTTKAAGLVQAAVERYG
RLDVLVNNAGRAIVGAAEEVTDAQLRDLMDLHFFGPAALVRAALPIMRAQGGGTIVQMSSQGGRTSFPGVSAYSASKFAL
EGWSEALAGEVARFGIGVMLVEPSRFRTAFNTADVLDFTAVSPTYREILADVRADMAGADGNQEGDPVKAAQIIVSLAHS
EEVPLRLPLGAEAVERLTAAYRRSLEEVSQWAELARSADFADVPASMRPI
>Mature_289_residues
TTATASQTWIITGASKGLGRALAEAALAAGDQVVAAVRNPDAMADLITNFGDRVTSVQFDARDTTKAAGLVQAAVERYGR
LDVLVNNAGRAIVGAAEEVTDAQLRDLMDLHFFGPAALVRAALPIMRAQGGGTIVQMSSQGGRTSFPGVSAYSASKFALE
GWSEALAGEVARFGIGVMLVEPSRFRTAFNTADVLDFTAVSPTYREILADVRADMAGADGNQEGDPVKAAQIIVSLAHSE
EVPLRLPLGAEAVERLTAAYRRSLEEVSQWAELARSADFADVPASMRPI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=249, Percent_Identity=34.136546184739, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI7657478, Length=260, Percent_Identity=32.6923076923077, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI4503817, Length=181, Percent_Identity=30.3867403314917, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI223718074, Length=297, Percent_Identity=29.2929292929293, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI157739938, Length=194, Percent_Identity=26.8041237113402, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI150247226, Length=187, Percent_Identity=32.0855614973262, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI32455239, Length=180, Percent_Identity=32.2222222222222, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI5031765, Length=180, Percent_Identity=32.2222222222222, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI32483357, Length=190, Percent_Identity=30.5263157894737, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI22507405, Length=182, Percent_Identity=29.6703296703297, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI50726952, Length=193, Percent_Identity=34.1968911917098, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI19743808, Length=181, Percent_Identity=31.4917127071823, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI7706318, Length=180, Percent_Identity=29.4444444444444, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI40548397, Length=187, Percent_Identity=28.3422459893048, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI214010158, Length=187, Percent_Identity=28.3422459893048, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI214010156, Length=187, Percent_Identity=28.3422459893048, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI22758144, Length=187, Percent_Identity=28.3422459893048, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI119392083, Length=184, Percent_Identity=30.4347826086957, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI44680136, Length=192, Percent_Identity=26.5625, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI44680133, Length=192, Percent_Identity=26.5625, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI17738292, Length=192, Percent_Identity=26.5625, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI126723191, Length=172, Percent_Identity=30.8139534883721, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1786701, Length=193, Percent_Identity=35.2331606217617, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87082100, Length=184, Percent_Identity=34.7826086956522, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI87082160, Length=187, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789208, Length=183, Percent_Identity=31.1475409836066, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787335, Length=178, Percent_Identity=28.0898876404494, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788459, Length=193, Percent_Identity=30.0518134715026, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787820, Length=176, Percent_Identity=26.1363636363636, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786812, Length=186, Percent_Identity=29.5698924731183, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=189, Percent_Identity=31.7460317460317, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=186, Percent_Identity=34.4086021505376, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71997402, Length=176, Percent_Identity=30.1136363636364, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=197, Percent_Identity=32.994923857868, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17570069, Length=176, Percent_Identity=31.8181818181818, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=183, Percent_Identity=30.0546448087432, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=185, Percent_Identity=27.027027027027, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=198, Percent_Identity=26.2626262626263, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17568967, Length=214, Percent_Identity=29.9065420560748, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=198, Percent_Identity=26.2626262626263, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=194, Percent_Identity=29.3814432989691, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=210, Percent_Identity=29.0476190476191, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=243, Percent_Identity=28.8065843621399, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=29.9492385786802, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322861, Length=193, Percent_Identity=32.6424870466321, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322067, Length=173, Percent_Identity=31.7919075144509, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322226, Length=163, Percent_Identity=32.5153374233129, Blast_Score=72, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6322227, Length=169, Percent_Identity=29.585798816568, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21358495, Length=189, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI21356301, Length=189, Percent_Identity=31.2169312169312, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24643142, Length=188, Percent_Identity=31.9148936170213, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571526, Length=210, Percent_Identity=30, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357041, Length=194, Percent_Identity=30.4123711340206, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355319, Length=192, Percent_Identity=28.6458333333333, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=30.5263157894737, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24644339, Length=217, Percent_Identity=29.4930875576037, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI23397609, Length=181, Percent_Identity=31.4917127071823, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30511; Mature: 30380

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTATASQTWIITGASKGLGRALAEAALAAGDQVVAAVRNPDAMADLITNFGDRVTSVQF
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCHHEEEEE
DARDTTKAAGLVQAAVERYGRLDVLVNNAGRAIVGAAEEVTDAQLRDLMDLHFFGPAALV
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHCCHHHHH
RAALPIMRAQGGGTIVQMSSQGGRTSFPGVSAYSASKFALEGWSEALAGEVARFGIGVML
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEE
VEPSRFRTAFNTADVLDFTAVSPTYREILADVRADMAGADGNQEGDPVKAAQIIVSLAHS
ECCHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCC
EEVPLRLPLGAEAVERLTAAYRRSLEEVSQWAELARSADFADVPASMRPI
CCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTATASQTWIITGASKGLGRALAEAALAAGDQVVAAVRNPDAMADLITNFGDRVTSVQF
CCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCHHEEEEE
DARDTTKAAGLVQAAVERYGRLDVLVNNAGRAIVGAAEEVTDAQLRDLMDLHFFGPAALV
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHCCHHHHH
RAALPIMRAQGGGTIVQMSSQGGRTSFPGVSAYSASKFALEGWSEALAGEVARFGIGVML
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEE
VEPSRFRTAFNTADVLDFTAVSPTYREILADVRADMAGADGNQEGDPVKAAQIIVSLAHS
ECCHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCC
EEVPLRLPLGAEAVERLTAAYRRSLEEVSQWAELARSADFADVPASMRPI
CCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 8396117 [H]