| Definition | Mycobacterium sp. KMS chromosome, complete genome. |
|---|---|
| Accession | NC_008705 |
| Length | 5,737,227 |
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The map label for this gene is fabG [H]
Identifier: 119868501
GI number: 119868501
Start: 2589540
End: 2590331
Strand: Reverse
Name: fabG [H]
Synonym: Mkms_2466
Alternate gene names: 119868501
Gene position: 2590331-2589540 (Counterclockwise)
Preceding gene: 119868502
Following gene: 119868500
Centisome position: 45.15
GC content: 70.33
Gene sequence:
>792_bases ATGACTGCCGATTCACCCACGCTCCAGACCGCCGTGGTCACCGGCGCCGGATCCGGGATCGGCCGCGCCATAGCGACGAC GCTCGCGGCCCGCGGCTGGCGCATCATCGTCACCGACGTGAACCTCACCGGGGCCCAGGAGACGGTGGCCGGACTCGAGG ATGCCGCCGGCCGCGGCCACGAGGCCCTGCAGTTGGACGTCACCGACGCCGCCGCGGCCGCCCGGCTCGCCGACGACGTC GCCGACCGGCTGGGCCTGGACGCGTGGGTCAACAACGCCGGCGTATCGGCGATGGAGCGGTTCGTCGACGTCACACCCGG CCAGTACGACCGCACCCTGGACATCAACACCAAGGCGGTGTTCTTCTGCGGGCAGGCCGCGGCGCGGGCGATGATCCGCA CCGGGCGCCAGGGCACCATCGTCAACACCGCGTCCATGGCCGCCAAACAGGGCCGCGTACCGTTCCTCACCGACTATGTG GCGTCGAAGTTCGCGGTGCTCGGCCTGACGCAGGCGATGGCCTACGAGCTGGCCGACCACCAGATCACGGTGAACTGCGT GTGCCCCGGCTTCGTCGCCACCCCCATGCAGTCGCGGGAACTGGAGTGGGAGGCGCGGCTGACCGGCTCCACCCCGGACG CGGTGCGTCAAAGCTGGATCGACGCAACGCCGTTGGCCCGGTTGCAGACTCCGGACGACGTCGCCCGCGCGGTGGCGTTC CTGGTCTCCGACGACGCCCGGTTCATCACCGGGGAAGCTCTTTCGGTCAACGGCGGTGCCTACATGGATTGA
Upstream 100 bases:
>100_bases CGCGCCACGTCGACCGGTACGCCGAGGCCTACTCCCTGTGGCGCACCCTCGGCGGCGTGCTCACCCCCGTCTCCCACCAA CTCGCCCGAAAGGCCAAGTG
Downstream 100 bases:
>100_bases GCCGGGGCCGCCGACCCGGTGAACTCGATCCAGCCAACCCAGTAGGAAGTGAGTACCCATGAAGATCCCGAAGCTCGGCC GGCGCCCAGCGCGGCGGAAA
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 263; Mature: 262
Protein sequence:
>263_residues MTADSPTLQTAVVTGAGSGIGRAIATTLAARGWRIIVTDVNLTGAQETVAGLEDAAGRGHEALQLDVTDAAAAARLADDV ADRLGLDAWVNNAGVSAMERFVDVTPGQYDRTLDINTKAVFFCGQAAARAMIRTGRQGTIVNTASMAAKQGRVPFLTDYV ASKFAVLGLTQAMAYELADHQITVNCVCPGFVATPMQSRELEWEARLTGSTPDAVRQSWIDATPLARLQTPDDVARAVAF LVSDDARFITGEALSVNGGAYMD
Sequences:
>Translated_263_residues MTADSPTLQTAVVTGAGSGIGRAIATTLAARGWRIIVTDVNLTGAQETVAGLEDAAGRGHEALQLDVTDAAAAARLADDV ADRLGLDAWVNNAGVSAMERFVDVTPGQYDRTLDINTKAVFFCGQAAARAMIRTGRQGTIVNTASMAAKQGRVPFLTDYV ASKFAVLGLTQAMAYELADHQITVNCVCPGFVATPMQSRELEWEARLTGSTPDAVRQSWIDATPLARLQTPDDVARAVAF LVSDDARFITGEALSVNGGAYMD >Mature_262_residues TADSPTLQTAVVTGAGSGIGRAIATTLAARGWRIIVTDVNLTGAQETVAGLEDAAGRGHEALQLDVTDAAAAARLADDVA DRLGLDAWVNNAGVSAMERFVDVTPGQYDRTLDINTKAVFFCGQAAARAMIRTGRQGTIVNTASMAAKQGRVPFLTDYVA SKFAVLGLTQAMAYELADHQITVNCVCPGFVATPMQSRELEWEARLTGSTPDAVRQSWIDATPLARLQTPDDVARAVAFL VSDDARFITGEALSVNGGAYMD
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=38.8461538461538, Blast_Score=157, Evalue=6e-39, Organism=Homo sapiens, GI32483357, Length=261, Percent_Identity=35.632183908046, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=32.4110671936759, Blast_Score=109, Evalue=3e-24, Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=31.3492063492063, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI66933014, Length=233, Percent_Identity=28.755364806867, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI142976729, Length=195, Percent_Identity=33.8461538461538, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI40807363, Length=192, Percent_Identity=31.7708333333333, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI126723750, Length=265, Percent_Identity=31.6981132075472, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI5031737, Length=261, Percent_Identity=30.2681992337165, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=25.390625, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI31542939, Length=247, Percent_Identity=30.3643724696356, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI210032110, Length=190, Percent_Identity=28.9473684210526, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI59889578, Length=239, Percent_Identity=30.1255230125523, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI310128830, Length=199, Percent_Identity=28.643216080402, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI310115468, Length=199, Percent_Identity=28.643216080402, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI4758504, Length=268, Percent_Identity=28.3582089552239, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=27.34375, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI109715829, Length=255, Percent_Identity=25.4901960784314, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI20149619, Length=233, Percent_Identity=27.4678111587983, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI126723191, Length=198, Percent_Identity=34.8484848484849, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI7657478, Length=251, Percent_Identity=27.8884462151394, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=32.48730964467, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI25282469, Length=220, Percent_Identity=29.5454545454545, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI83715985, Length=267, Percent_Identity=27.3408239700375, Blast_Score=65, Evalue=8e-11, Organism=Homo sapiens, GI50726952, Length=199, Percent_Identity=29.6482412060301, Blast_Score=65, Evalue=9e-11, Organism=Escherichia coli, GI1787335, Length=255, Percent_Identity=36.4705882352941, Blast_Score=143, Evalue=9e-36, Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=33.5907335907336, Blast_Score=128, Evalue=3e-31, Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=35, Blast_Score=127, Evalue=6e-31, Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=33.596837944664, Blast_Score=127, Evalue=8e-31, Organism=Escherichia coli, GI1789208, Length=262, Percent_Identity=33.206106870229, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=32.8125, Blast_Score=114, Evalue=9e-27, Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=34.9019607843137, Blast_Score=112, Evalue=3e-26, Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=31.6205533596838, Blast_Score=111, Evalue=4e-26, Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=30.5555555555556, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=31.0077519379845, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=31.1284046692607, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787526, Length=252, Percent_Identity=27.3809523809524, Blast_Score=75, Evalue=6e-15, Organism=Escherichia coli, GI2367365, Length=257, Percent_Identity=27.2373540856031, Blast_Score=65, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=35.2941176470588, Blast_Score=145, Evalue=3e-35, Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=31.6205533596838, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=32.5670498084291, Blast_Score=108, Evalue=4e-24, Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=30.3501945525292, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI193203115, Length=218, Percent_Identity=32.5688073394495, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI193203117, Length=218, Percent_Identity=32.5688073394495, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=30.7291666666667, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=29.4573643410853, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=31.1538461538462, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=32.8125, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=29.4776119402985, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=31.496062992126, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=29.1044776119403, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=27.34375, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17561272, Length=244, Percent_Identity=28.6885245901639, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=25.296442687747, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=26.865671641791, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=28.8973384030418, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=26.3940520446097, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=27.3076923076923, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17551412, Length=271, Percent_Identity=28.7822878228782, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=28.3018867924528, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17560332, Length=274, Percent_Identity=29.5620437956204, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17567345, Length=192, Percent_Identity=30.7291666666667, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17544670, Length=273, Percent_Identity=26.7399267399267, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=26.7657992565056, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=26.8199233716475, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17538480, Length=272, Percent_Identity=27.2058823529412, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17565030, Length=271, Percent_Identity=28.4132841328413, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17562990, Length=272, Percent_Identity=25, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=26.0223048327138, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=24.4444444444444, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17507613, Length=223, Percent_Identity=28.2511210762332, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17538182, Length=267, Percent_Identity=25.8426966292135, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI32563809, Length=223, Percent_Identity=28.2511210762332, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17568967, Length=194, Percent_Identity=27.319587628866, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=25.5639097744361, Blast_Score=65, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=188, Percent_Identity=27.6595744680851, Blast_Score=68, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6323882, Length=242, Percent_Identity=28.5123966942149, Blast_Score=62, Evalue=8e-11, Organism=Drosophila melanogaster, GI24639444, Length=254, Percent_Identity=34.251968503937, Blast_Score=138, Evalue=3e-33, Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=29.2490118577075, Blast_Score=100, Evalue=2e-21, Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=31.25, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=30.2325581395349, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=31.1284046692607, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=29.1338582677165, Blast_Score=94, Evalue=6e-20, Organism=Drosophila melanogaster, GI24643142, Length=255, Percent_Identity=32.156862745098, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI24649181, Length=190, Percent_Identity=30.5263157894737, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI17737361, Length=267, Percent_Identity=29.5880149812734, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI221510726, Length=186, Percent_Identity=32.7956989247312, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI24641232, Length=248, Percent_Identity=29.4354838709677, Blast_Score=73, Evalue=1e-13, Organism=Drosophila melanogaster, GI24581726, Length=194, Percent_Identity=28.3505154639175, Blast_Score=71, Evalue=9e-13, Organism=Drosophila melanogaster, GI24584748, Length=193, Percent_Identity=31.0880829015544, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI161076933, Length=193, Percent_Identity=31.0880829015544, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI18859837, Length=188, Percent_Identity=29.7872340425532, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI21355631, Length=172, Percent_Identity=30.8139534883721, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI281364494, Length=213, Percent_Identity=27.6995305164319, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 27680; Mature: 27549
Theoretical pI: Translated: 4.49; Mature: 4.49
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTADSPTLQTAVVTGAGSGIGRAIATTLAARGWRIIVTDVNLTGAQETVAGLEDAAGRGH CCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCC EALQLDVTDAAAAARLADDVADRLGLDAWVNNAGVSAMERFVDVTPGQYDRTLDINTKAV CEEEEECHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHCCCCCCCCCEEECCCEEE FFCGQAAARAMIRTGRQGTIVNTASMAAKQGRVPFLTDYVASKFAVLGLTQAMAYELADH EEECHHHHHHHHHCCCCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC QITVNCVCPGFVATPMQSRELEWEARLTGSTPDAVRQSWIDATPLARLQTPDDVARAVAF EEEEEEECCCHHCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCHHCCCHHHHHHHHHH LVSDDARFITGEALSVNGGAYMD HHCCCCEEEECCEEEECCCCCCC >Mature Secondary Structure TADSPTLQTAVVTGAGSGIGRAIATTLAARGWRIIVTDVNLTGAQETVAGLEDAAGRGH CCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCC EALQLDVTDAAAAARLADDVADRLGLDAWVNNAGVSAMERFVDVTPGQYDRTLDINTKAV CEEEEECHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHCCCCCCCCCEEECCCEEE FFCGQAAARAMIRTGRQGTIVNTASMAAKQGRVPFLTDYVASKFAVLGLTQAMAYELADH EEECHHHHHHHHHCCCCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC QITVNCVCPGFVATPMQSRELEWEARLTGSTPDAVRQSWIDATPLARLQTPDDVARAVAF EEEEEEECCCHHCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCHHCCCHHHHHHHHHH LVSDDARFITGEALSVNGGAYMD HHCCCCEEEECCEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA