Click here to switch to the map view.

The map label for this gene is xylB [H]

Identifier: 119868502

GI number: 119868502

Start: 2590331

End: 2591815

Strand: Reverse

Name: xylB [H]

Synonym: Mkms_2467

Alternate gene names: 119868502

Gene position: 2591815-2590331 (Counterclockwise)

Preceding gene: 119868505

Following gene: 119868501

Centisome position: 45.18

GC content: 71.31

Gene sequence:

>1485_bases
ATGTCGCAGTTCACGATCGGTGTCGACATCGGCACCACGGGGACCAAGACGGTGCTCGTCGACCTCGCGGCCGGGCGCAT
CGTCGCCCAGGCGTCCGCCGAGAGCCGGCTCTTCGCCGATGCGCCCGGACATGCGGAGGCCGACCCGGCACAGTGGATCA
ACAACGCGCACAGCACGATTCGGGCCGTCCTCGCGGAGTCCGGGGTGACCCCCGGACAGGTCGGCGCGCTGTCCACCACC
GGTATGGTGCCCGCGGTCGTGCCCGTCGACGCCCACGGCGTCCCGGTGCGCCGGGCGCTGCTGCAGAACGACGCCCGCGC
CACCGCACAGATCGAGCGGTTGCGGGAGGCGCTCGACGCCGCCGACGTCCTGGCCGCCACGGGATCGGCGATCACGCAGC
AGTCGGTGGCACCGACCGCAATGTGGCTGCGCGAGAACGATCCTGACACCTGGCACCGGACCGCCCGTCTGGTCGGGTCG
TACGACTGGGTGCTCATGGCACTGGGCGCGGGCCCCCACGTCGAATTGAACTGGGCCATCGAGTCCGGCCTGGGCACCCT
CGACGGACAGCGGTACGAGCCGATGTTCGCCGCGGCCGACCTCGGCGCGGACACCATGCCCGAGGTGCTGGCCCCCGGCG
CTCAGGCCGGAACCCTCAGTGCCGCAGCGGCGGCGGCCACCGGTCTTCCCGAGGGGCTGCCGCTGATCGTCGGCGGGGCC
GATCACGTCCTGTCCGCGTACGCGGCAGGAGTGAACGCCGCGGGTGACTGGCTGGTGAAGCTCGGCGGCGCGGGCGACGT
CCTTGCCGCCAGCGATTCACCCGTCATCGACGGCCGGCTCTACCTGGACGCCCATCCGGTACCGGGCCGCTGGCTGCCCA
ACGGGTGCATGGCCACCAGCGGCAGCCTGATCCGGTGGTTCCAGACCCTGATCGGCGGCGTGGACCTCCTGCAGCTCGAC
GACGAGGCAGCCGGCCGCGACGCCGCCGAAATCCTCTGCCTGCCTTACTTTCTCGGCGAGAAGAGTCCTCTGCACGATCC
CGATCTGCGCGGCGCCTTCGTCGGACTCGACCTGGCCCACACCCGGGCGGACATGTACCGGTCGGTGCTCGAGGCGATCG
CGTTCGGGTTCAGACACCACACCGACGTGTTCACCTCGATCGGCGTCCCGCTGCAGCGCGCGATGGTCACCAACGGCGGC
AGCAAATCGGTGCTGTGGAAACAGATCCTCGCCGACGTCCTCGACACTCCCCTGTTCCCCGTGATCGGGCATCCGGGCGC
CTCGCTCGGCGCCGCGGTGATCGCCGCGATCGGTGTCGGGGCGCTCGACGACTGGGACGGCGCCGCGCGCTTCCTCACCC
TCGGCGACGCCGTCGAACCCGACCCGCGCCACGTCGACCGGTACGCCGAGGCCTACTCCCTGTGGCGCACCCTCGGCGGC
GTGCTCACCCCCGTCTCCCACCAACTCGCCCGAAAGGCCAAGTGA

Upstream 100 bases:

>100_bases
ACGTGCGGCAGTGCAGCGTTTTACGTGACGGTTACACACAACGTGTGAGAATCTAACAGATACGCAGTACGGTCAGCATC
CGAGCAAACGAGAGGACGGC

Downstream 100 bases:

>100_bases
TGACTGCCGATTCACCCACGCTCCAGACCGCCGTGGTCACCGGCGCCGGATCCGGGATCGGCCGCGCCATAGCGACGACG
CTCGCGGCCCGCGGCTGGCG

Product: carbohydrate kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MSQFTIGVDIGTTGTKTVLVDLAAGRIVAQASAESRLFADAPGHAEADPAQWINNAHSTIRAVLAESGVTPGQVGALSTT
GMVPAVVPVDAHGVPVRRALLQNDARATAQIERLREALDAADVLAATGSAITQQSVAPTAMWLRENDPDTWHRTARLVGS
YDWVLMALGAGPHVELNWAIESGLGTLDGQRYEPMFAAADLGADTMPEVLAPGAQAGTLSAAAAAATGLPEGLPLIVGGA
DHVLSAYAAGVNAAGDWLVKLGGAGDVLAASDSPVIDGRLYLDAHPVPGRWLPNGCMATSGSLIRWFQTLIGGVDLLQLD
DEAAGRDAAEILCLPYFLGEKSPLHDPDLRGAFVGLDLAHTRADMYRSVLEAIAFGFRHHTDVFTSIGVPLQRAMVTNGG
SKSVLWKQILADVLDTPLFPVIGHPGASLGAAVIAAIGVGALDDWDGAARFLTLGDAVEPDPRHVDRYAEAYSLWRTLGG
VLTPVSHQLARKAK

Sequences:

>Translated_494_residues
MSQFTIGVDIGTTGTKTVLVDLAAGRIVAQASAESRLFADAPGHAEADPAQWINNAHSTIRAVLAESGVTPGQVGALSTT
GMVPAVVPVDAHGVPVRRALLQNDARATAQIERLREALDAADVLAATGSAITQQSVAPTAMWLRENDPDTWHRTARLVGS
YDWVLMALGAGPHVELNWAIESGLGTLDGQRYEPMFAAADLGADTMPEVLAPGAQAGTLSAAAAAATGLPEGLPLIVGGA
DHVLSAYAAGVNAAGDWLVKLGGAGDVLAASDSPVIDGRLYLDAHPVPGRWLPNGCMATSGSLIRWFQTLIGGVDLLQLD
DEAAGRDAAEILCLPYFLGEKSPLHDPDLRGAFVGLDLAHTRADMYRSVLEAIAFGFRHHTDVFTSIGVPLQRAMVTNGG
SKSVLWKQILADVLDTPLFPVIGHPGASLGAAVIAAIGVGALDDWDGAARFLTLGDAVEPDPRHVDRYAEAYSLWRTLGG
VLTPVSHQLARKAK
>Mature_493_residues
SQFTIGVDIGTTGTKTVLVDLAAGRIVAQASAESRLFADAPGHAEADPAQWINNAHSTIRAVLAESGVTPGQVGALSTTG
MVPAVVPVDAHGVPVRRALLQNDARATAQIERLREALDAADVLAATGSAITQQSVAPTAMWLRENDPDTWHRTARLVGSY
DWVLMALGAGPHVELNWAIESGLGTLDGQRYEPMFAAADLGADTMPEVLAPGAQAGTLSAAAAAATGLPEGLPLIVGGAD
HVLSAYAAGVNAAGDWLVKLGGAGDVLAASDSPVIDGRLYLDAHPVPGRWLPNGCMATSGSLIRWFQTLIGGVDLLQLDD
EAAGRDAAEILCLPYFLGEKSPLHDPDLRGAFVGLDLAHTRADMYRSVLEAIAFGFRHHTDVFTSIGVPLQRAMVTNGGS
KSVLWKQILADVLDTPLFPVIGHPGASLGAAVIAAIGVGALDDWDGAARFLTLGDAVEPDPRHVDRYAEAYSLWRTLGGV
LTPVSHQLARKAK

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=440, Percent_Identity=20, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI189409120, Length=440, Percent_Identity=20.2272727272727, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4504007, Length=440, Percent_Identity=20.2272727272727, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789987, Length=488, Percent_Identity=25.8196721311475, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1790005, Length=471, Percent_Identity=24.6284501061571, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1787789, Length=504, Percent_Identity=25.5952380952381, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1789168, Length=479, Percent_Identity=24.0083507306889, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789138, Length=487, Percent_Identity=23.8193018480493, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 51490; Mature: 51359

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFTIGVDIGTTGTKTVLVDLAAGRIVAQASAESRLFADAPGHAEADPAQWINNAHSTI
CCCEEEEEEECCCCCCEEEEEECCCCEEEECCCCCCEEECCCCCCCCCHHHHHHHHHHHH
RAVLAESGVTPGQVGALSTTGMVPAVVPVDAHGVPVRRALLQNDARATAQIERLREALDA
HHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
ADVLAATGSAITQQSVAPTAMWLRENDPDTWHRTARLVGSYDWVLMALGAGPHVELNWAI
HHHHHHCCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEE
ESGLGTLDGQRYEPMFAAADLGADTMPEVLAPGAQAGTLSAAAAAATGLPEGLPLIVGGA
ECCCCCCCCCCCCCHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHCCCCCCCEEEECCH
DHVLSAYAAGVNAAGDWLVKLGGAGDVLAASDSPVIDGRLYLDAHPVPGRWLPNGCMATS
HHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCEECCEEEEECCCCCCCCCCCCCCCCC
GSLIRWFQTLIGGVDLLQLDDEAAGRDAAEILCLPYFLGEKSPLHDPDLRGAFVGLDLAH
CHHHHHHHHHHCCCEEEEECCCCCCCCHHHHEEEHHHHCCCCCCCCCCCCCEEEECHHHH
TRADMYRSVLEAIAFGFRHHTDVFTSIGVPLQRAMVTNGGSKSVLWKQILADVLDTPLFP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCE
VIGHPGASLGAAVIAAIGVGALDDWDGAARFLTLGDAVEPDPRHVDRYAEAYSLWRTLGG
ECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
VLTPVSHQLARKAK
HHHHHHHHHHHCCC
>Mature Secondary Structure 
SQFTIGVDIGTTGTKTVLVDLAAGRIVAQASAESRLFADAPGHAEADPAQWINNAHSTI
CCEEEEEEECCCCCCEEEEEECCCCEEEECCCCCCEEECCCCCCCCCHHHHHHHHHHHH
RAVLAESGVTPGQVGALSTTGMVPAVVPVDAHGVPVRRALLQNDARATAQIERLREALDA
HHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
ADVLAATGSAITQQSVAPTAMWLRENDPDTWHRTARLVGSYDWVLMALGAGPHVELNWAI
HHHHHHCCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEE
ESGLGTLDGQRYEPMFAAADLGADTMPEVLAPGAQAGTLSAAAAAATGLPEGLPLIVGGA
ECCCCCCCCCCCCCHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHCCCCCCCEEEECCH
DHVLSAYAAGVNAAGDWLVKLGGAGDVLAASDSPVIDGRLYLDAHPVPGRWLPNGCMATS
HHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCEECCEEEEECCCCCCCCCCCCCCCCC
GSLIRWFQTLIGGVDLLQLDDEAAGRDAAEILCLPYFLGEKSPLHDPDLRGAFVGLDLAH
CHHHHHHHHHHCCCEEEEECCCCCCCCHHHHEEEHHHHCCCCCCCCCCCCCEEEECHHHH
TRADMYRSVLEAIAFGFRHHTDVFTSIGVPLQRAMVTNGGSKSVLWKQILADVLDTPLFP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCE
VIGHPGASLGAAVIAAIGVGALDDWDGAARFLTLGDAVEPDPRHVDRYAEAYSLWRTLGG
ECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
VLTPVSHQLARKAK
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1660563 [H]