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The map label for this gene is hypB [H]

Identifier: 119868227

GI number: 119868227

Start: 2308285

End: 2309070

Strand: Reverse

Name: hypB [H]

Synonym: Mkms_2191

Alternate gene names: 119868227

Gene position: 2309070-2308285 (Counterclockwise)

Preceding gene: 119868228

Following gene: 119868226

Centisome position: 40.25

GC content: 67.43

Gene sequence:

>786_bases
ATGTGCGCAACCTGTGGCTGCGGCGGCGACGACGCGGTGATCACCCTGGGCCACGCCCACCCGCACCAGCACGCCCACCC
GCACCAGCACGCCCATGATCATGATCACCCCCACACCGAGACGGTGACCCTGGAACAGAAGGTGCTCGCGCGCAACGACG
ACATCGCCGCGCACAATCGCCGCTGGCTCGCCGAACGCGACATCCTCGCGCTCAACGTCACCAGTTCCCCGGGGGCCGGC
AAGACCACCCTGCTGGAACGGACCATCCGCGAACTTGGTGCGCACCGCCCCATCGCCGTGATCGAGGGTGACCAGGAGAC
GGCGCTCGACGCCGATCGCATCCGTGCGGCAGGCGCCCGGGCCGTGCAGGTCAACACCGGCGCCGGGTGCCACCTCGACG
CACTGATGGTGCGCCGCGCCCTCGAGGCGCTCGACCCCGACCCCGGCACGCTGCTGTTCATCGAGAACGTCGGCAACCTC
GTCTGCCCCGCGCTGTTCGACCTCGGTGAGCACGGCAAGGTGGTCGTCATCTCGGTCACCGAGGGCACCGACAAACCGTT
GAAGTACCCGCACATGTTTGCCGCCGCCGGCTTGATCATCGTCAACAAGACCGATCTGTTGCCGTACGTGGACTTCGACG
TCGACGCGTGCACCCGCTACGCACAATCGCTGAACCCCGGCGTCGGCGTGCTGCCGGTGTCGGCCACCACGGGCCGAGGT
CTCGAGCAGTGGTACGGGTGGATCGAATTTCTGGCAAACCCGTCCAAGAACCCGGTCATGTCGTGA

Upstream 100 bases:

>100_bases
AACTGACCGACCTGATCCTGCTGTGCCCGTGCGGCAGCGCCGACGTGGAAGTGCGCGCCGGCCGCGACCTGCGGATCCTC
TCGATGGAAGTGAGCTGACC

Downstream 100 bases:

>100_bases
GACCCGTTGACAGAACAATCGCGTCGGAGTAGACCCAGAACTAGCGCCGCGCAAGTGGGCCGAGGGTCGACTCCGGCGGC
GCAGGGGTCGTCAGCCCCGA

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MCATCGCGGDDAVITLGHAHPHQHAHPHQHAHDHDHPHTETVTLEQKVLARNDDIAAHNRRWLAERDILALNVTSSPGAG
KTTLLERTIRELGAHRPIAVIEGDQETALDADRIRAAGARAVQVNTGAGCHLDALMVRRALEALDPDPGTLLFIENVGNL
VCPALFDLGEHGKVVVISVTEGTDKPLKYPHMFAAAGLIIVNKTDLLPYVDFDVDACTRYAQSLNPGVGVLPVSATTGRG
LEQWYGWIEFLANPSKNPVMS

Sequences:

>Translated_261_residues
MCATCGCGGDDAVITLGHAHPHQHAHPHQHAHDHDHPHTETVTLEQKVLARNDDIAAHNRRWLAERDILALNVTSSPGAG
KTTLLERTIRELGAHRPIAVIEGDQETALDADRIRAAGARAVQVNTGAGCHLDALMVRRALEALDPDPGTLLFIENVGNL
VCPALFDLGEHGKVVVISVTEGTDKPLKYPHMFAAAGLIIVNKTDLLPYVDFDVDACTRYAQSLNPGVGVLPVSATTGRG
LEQWYGWIEFLANPSKNPVMS
>Mature_261_residues
MCATCGCGGDDAVITLGHAHPHQHAHPHQHAHDHDHPHTETVTLEQKVLARNDDIAAHNRRWLAERDILALNVTSSPGAG
KTTLLERTIRELGAHRPIAVIEGDQETALDADRIRAAGARAVQVNTGAGCHLDALMVRRALEALDPDPGTLLFIENVGNL
VCPALFDLGEHGKVVVISVTEGTDKPLKYPHMFAAAGLIIVNKTDLLPYVDFDVDACTRYAQSLNPGVGVLPVSATTGRG
LEQWYGWIEFLANPSKNPVMS

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=285, Percent_Identity=45.9649122807018, Blast_Score=246, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 28130; Mature: 28130

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCATCGCGGDDAVITLGHAHPHQHAHPHQHAHDHDHPHTETVTLEQKVLARNDDIAAHNR
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCCCCCC
RWLAERDILALNVTSSPGAGKTTLLERTIRELGAHRPIAVIEGDQETALDADRIRAAGAR
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHCCHHHHHHCCCE
AVQVNTGAGCHLDALMVRRALEALDPDPGTLLFIENVGNLVCPALFDLGEHGKVVVISVT
EEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCCCCCEEEEEEE
EGTDKPLKYPHMFAAAGLIIVNKTDLLPYVDFDVDACTRYAQSLNPGVGVLPVSATTGRG
CCCCCCCCCCHHHHHCCEEEEECCCCCEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCC
LEQWYGWIEFLANPSKNPVMS
HHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MCATCGCGGDDAVITLGHAHPHQHAHPHQHAHDHDHPHTETVTLEQKVLARNDDIAAHNR
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCCCCCC
RWLAERDILALNVTSSPGAGKTTLLERTIRELGAHRPIAVIEGDQETALDADRIRAAGAR
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHCCHHHHHHCCCE
AVQVNTGAGCHLDALMVRRALEALDPDPGTLLFIENVGNLVCPALFDLGEHGKVVVISVT
EEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCCCCCEEEEEEE
EGTDKPLKYPHMFAAAGLIIVNKTDLLPYVDFDVDACTRYAQSLNPGVGVLPVSATTGRG
CCCCCCCCCCHHHHHCCEEEEECCCCCEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCC
LEQWYGWIEFLANPSKNPVMS
HHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]