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The map label for this gene is hypA [H]

Identifier: 119868228

GI number: 119868228

Start: 2309073

End: 2309492

Strand: Reverse

Name: hypA [H]

Synonym: Mkms_2192

Alternate gene names: 119868228

Gene position: 2309492-2309073 (Counterclockwise)

Preceding gene: 119868231

Following gene: 119868227

Centisome position: 40.25

GC content: 71.19

Gene sequence:

>420_bases
ATGGCCACCACGGCGATCGGTGATTCCACCCGCCGGGCCCGCACACCGGCCTATCGTGAGGGCACCGCCCCCGTCGAGGA
CGGCACACCGATGCACGAGATGGCGATCACCCAGAGCGTTGTCGACGCGGTCTGTGACCACGCCGCCGGCCGACGCGTGC
ACAGCGTCCGGCTCGAGGTGGGCGCACTGTGCGCCGTGGTGCCCGATGCGATGCGGTTCTGCTTCGAGCTGGCCACCGAG
GGCACCGCCGCCGACGGCGCCCGCCTCGACCTCGATGTGCGGCCGGGACTCGCGCGCTGCCGCACCTGTGACACCGACTT
CGAACTGACCGACCTGATCCTGCTGTGCCCGTGCGGCAGCGCCGACGTGGAAGTGCGCGCCGGCCGCGACCTGCGGATCC
TCTCGATGGAAGTGAGCTGA

Upstream 100 bases:

>100_bases
CGCTAGAGGGACCCACCGACAAGTCGGCGTGAGCAGGCATCTAGCCGTCGAACACCACCCACCATAGACGAACACCTGTT
CGACTCAAGTGGACACGCCG

Downstream 100 bases:

>100_bases
CCATGTGCGCAACCTGTGGCTGCGGCGGCGACGACGCGGTGATCACCCTGGGCCACGCCCACCCGCACCAGCACGCCCAC
CCGCACCAGCACGCCCATGA

Product: hydrogenase nickel insertion protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MATTAIGDSTRRARTPAYREGTAPVEDGTPMHEMAITQSVVDAVCDHAAGRRVHSVRLEVGALCAVVPDAMRFCFELATE
GTAADGARLDLDVRPGLARCRTCDTDFELTDLILLCPCGSADVEVRAGRDLRILSMEVS

Sequences:

>Translated_139_residues
MATTAIGDSTRRARTPAYREGTAPVEDGTPMHEMAITQSVVDAVCDHAAGRRVHSVRLEVGALCAVVPDAMRFCFELATE
GTAADGARLDLDVRPGLARCRTCDTDFELTDLILLCPCGSADVEVRAGRDLRILSMEVS
>Mature_138_residues
ATTAIGDSTRRARTPAYREGTAPVEDGTPMHEMAITQSVVDAVCDHAAGRRVHSVRLEVGALCAVVPDAMRFCFELATEG
TAADGARLDLDVRPGLARCRTCDTDFELTDLILLCPCGSADVEVRAGRDLRILSMEVS

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789365, Length=112, Percent_Identity=35.7142857142857, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 14880; Mature: 14749

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
8.6 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTAIGDSTRRARTPAYREGTAPVEDGTPMHEMAITQSVVDAVCDHAAGRRVHSVRLEV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHH
GALCAVVPDAMRFCFELATEGTAADGARLDLDVRPGLARCRTCDTDFELTDLILLCPCGS
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHCCCCCCCCCCCEEEECCCCC
ADVEVRAGRDLRILSMEVS
CCEEEECCCCEEEEEEECC
>Mature Secondary Structure 
ATTAIGDSTRRARTPAYREGTAPVEDGTPMHEMAITQSVVDAVCDHAAGRRVHSVRLEV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHH
GALCAVVPDAMRFCFELATEGTAADGARLDLDVRPGLARCRTCDTDFELTDLILLCPCGS
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHCCCCCCCCCCCEEEECCCCC
ADVEVRAGRDLRILSMEVS
CCEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA