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The map label for this gene is 119867865

Identifier: 119867865

GI number: 119867865

Start: 1937595

End: 1938740

Strand: Reverse

Name: 119867865

Synonym: Mkms_1826

Alternate gene names: NA

Gene position: 1938740-1937595 (Counterclockwise)

Preceding gene: 119867866

Following gene: 119867856

Centisome position: 33.79

GC content: 67.28

Gene sequence:

>1146_bases
ATGAACGATGTCGCGATCATCGGTGTGGGGCTGCATCCGTTCGGCCGGTTCGAGGGTAAGTCGGCGATGCAGATGGGCGT
CGACGCGATCTTCGCCGCGGTCGACGACGCCGGCGTCGCGTGGTCGGATGTGCAGTTCGCCACCGGCGGCAGTTGGACGG
TGGCCAACCCCGACGCCATCGTCGGCATGGTCGGGCTCTCGGGTATTCCGTTCACCAATGTCTTCAACGCCTGCGCCACC
GCAGCGAGTGCGCTGAAGGCCTGCGCCGACGGAATCCGATTGGGCGACTACGACATCGGCATCGCGATCGGCCTGGACAA
GCATCCGCGCGGCGCCTTCACCGAGGATCCCGCACTGGTGGGCATGCCGTCCTGGTACGCGGAGAACGGCCAGTACCTGA
CCACGCAGTTCTTCGGTATGAAGGCCAATCGCTATCTGCACGATCACCAGATCTCCCACGCCACGCTCGCCAAGGTGGCC
GCCAAGAACTTCCGCAACGGGGCGCTCAACCCGAATGCGTTCCGGCGCAAGCCGATGACCGAGGAGCAGATCCTCGACTC
GACGATGCTGAACTATCCGCTCACGCAGTACATGTTCTGCGCGCCCGACGAAGGGGCCGCCGCGGTGGTGATGTGCCGCG
CCGACCTGGCCCACCGCTACACCTCGAAACCGGTGTACCTGCGCGCGGTGGAGGTCCGCACCCGGCAGTACGGCGCGTAC
GAGGTCAATACCACGTTCGCGCCCGTCGACGAGGACGTCGCGCCGACGGTGTACGCGGCCAGGTCGGCGTTCGAGAAGGC
CGGCATCGCGCCGACCGACGTCGACGTCGTCCAGTTGCAGGACACCGACGCCGGCGCGGAGATCATCCACATGGCCGAAT
GCGGATTCTGCGCCGACGGCGATCAGGAGAAGCTGCTGGCCGACGGCGCCACCGAGATCGGCGGCCCACTGCCGATCAAC
ACCGACGGTGGCCTGATCGCCAACGGCGAGCCGATCGGCGCATCGGGCCTGCGCCAGATCCACGAGCTGGTCCGGCAATT
GCGGGGCGAGGCCGGAGACCGACAGGTACCCGGTGAGCCACGGGTCGGGTTCGGGCAGCTCTACGGTGCGCCCGGTACCG
CCGCGGCCATGATCGTGTCCACCTGA

Upstream 100 bases:

>100_bases
ATCGAGGCGCTCAAGGACTCGGGCGCCATCGCCTGATCCCCGCAGCCCGCGAGCCACAGACACTTACCGTAAGCGTTACA
GTTGAGATATCATCACCGGC

Downstream 100 bases:

>100_bases
CCACCGCGAGCAGACAGAGAATCGCCCCGAAACACCTGCGTTTAGGCGATTCTGCGTCTGCTCGCCGAATTTTCCCGGCG
CTCACCGACTTCATCCCCAA

Product: thiolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MNDVAIIGVGLHPFGRFEGKSAMQMGVDAIFAAVDDAGVAWSDVQFATGGSWTVANPDAIVGMVGLSGIPFTNVFNACAT
AASALKACADGIRLGDYDIGIAIGLDKHPRGAFTEDPALVGMPSWYAENGQYLTTQFFGMKANRYLHDHQISHATLAKVA
AKNFRNGALNPNAFRRKPMTEEQILDSTMLNYPLTQYMFCAPDEGAAAVVMCRADLAHRYTSKPVYLRAVEVRTRQYGAY
EVNTTFAPVDEDVAPTVYAARSAFEKAGIAPTDVDVVQLQDTDAGAEIIHMAECGFCADGDQEKLLADGATEIGGPLPIN
TDGGLIANGEPIGASGLRQIHELVRQLRGEAGDRQVPGEPRVGFGQLYGAPGTAAAMIVST

Sequences:

>Translated_381_residues
MNDVAIIGVGLHPFGRFEGKSAMQMGVDAIFAAVDDAGVAWSDVQFATGGSWTVANPDAIVGMVGLSGIPFTNVFNACAT
AASALKACADGIRLGDYDIGIAIGLDKHPRGAFTEDPALVGMPSWYAENGQYLTTQFFGMKANRYLHDHQISHATLAKVA
AKNFRNGALNPNAFRRKPMTEEQILDSTMLNYPLTQYMFCAPDEGAAAVVMCRADLAHRYTSKPVYLRAVEVRTRQYGAY
EVNTTFAPVDEDVAPTVYAARSAFEKAGIAPTDVDVVQLQDTDAGAEIIHMAECGFCADGDQEKLLADGATEIGGPLPIN
TDGGLIANGEPIGASGLRQIHELVRQLRGEAGDRQVPGEPRVGFGQLYGAPGTAAAMIVST
>Mature_381_residues
MNDVAIIGVGLHPFGRFEGKSAMQMGVDAIFAAVDDAGVAWSDVQFATGGSWTVANPDAIVGMVGLSGIPFTNVFNACAT
AASALKACADGIRLGDYDIGIAIGLDKHPRGAFTEDPALVGMPSWYAENGQYLTTQFFGMKANRYLHDHQISHATLAKVA
AKNFRNGALNPNAFRRKPMTEEQILDSTMLNYPLTQYMFCAPDEGAAAVVMCRADLAHRYTSKPVYLRAVEVRTRQYGAY
EVNTTFAPVDEDVAPTVYAARSAFEKAGIAPTDVDVVQLQDTDAGAEIIHMAECGFCADGDQEKLLADGATEIGGPLPIN
TDGGLIANGEPIGASGLRQIHELVRQLRGEAGDRQVPGEPRVGFGQLYGAPGTAAAMIVST

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=375, Percent_Identity=29.6, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI302344760, Length=311, Percent_Identity=31.1897106109325, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI302344767, Length=304, Percent_Identity=30.9210526315789, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI302344762, Length=301, Percent_Identity=28.9036544850498, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI55956775, Length=279, Percent_Identity=25.4480286738351, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17537653, Length=376, Percent_Identity=29.2553191489362, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24585051, Length=378, Percent_Identity=29.1005291005291, Blast_Score=144, Evalue=9e-35,
Organism=Drosophila melanogaster, GI19921506, Length=374, Percent_Identity=28.6096256684492, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 40395; Mature: 40395

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDVAIIGVGLHPFGRFEGKSAMQMGVDAIFAAVDDAGVAWSDVQFATGGSWTVANPDAI
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEECCEEEECCCCEEECCCCCE
VGMVGLSGIPFTNVFNACATAASALKACADGIRLGDYDIGIAIGLDKHPRGAFTEDPALV
EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCEEEEEEEECCCCCCCCCCCCCCEE
GMPSWYAENGQYLTTQFFGMKANRYLHDHQISHATLAKVAAKNFRNGALNPNAFRRKPMT
CCCCHHCCCCCEEEEEEECCCCCCEEHHHCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCC
EEQILDSTMLNYPLTQYMFCAPDEGAAAVVMCRADLAHRYTSKPVYLRAVEVRTRQYGAY
HHHHHHHHHHCCCHHHEEEECCCCCCEEEEEEEHHHHHHHCCCCEEEEEEEEHHHCCCCE
EVNTTFAPVDEDVAPTVYAARSAFEKAGIAPTDVDVVQLQDTDAGAEIIHMAECGFCADG
EECCEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCC
DQEKLLADGATEIGGPLPINTDGGLIANGEPIGASGLRQIHELVRQLRGEAGDRQVPGEP
CHHHHHHCCCHHCCCCCEECCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
RVGFGQLYGAPGTAAAMIVST
CCCHHHEECCCCCEEEEEEEC
>Mature Secondary Structure
MNDVAIIGVGLHPFGRFEGKSAMQMGVDAIFAAVDDAGVAWSDVQFATGGSWTVANPDAI
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEECCEEEECCCCEEECCCCCE
VGMVGLSGIPFTNVFNACATAASALKACADGIRLGDYDIGIAIGLDKHPRGAFTEDPALV
EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCEEEEEEEECCCCCCCCCCCCCCEE
GMPSWYAENGQYLTTQFFGMKANRYLHDHQISHATLAKVAAKNFRNGALNPNAFRRKPMT
CCCCHHCCCCCEEEEEEECCCCCCEEHHHCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCC
EEQILDSTMLNYPLTQYMFCAPDEGAAAVVMCRADLAHRYTSKPVYLRAVEVRTRQYGAY
HHHHHHHHHHCCCHHHEEEECCCCCCEEEEEEEHHHHHHHCCCCEEEEEEEEHHHCCCCE
EVNTTFAPVDEDVAPTVYAARSAFEKAGIAPTDVDVVQLQDTDAGAEIIHMAECGFCADG
EECCEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCC
DQEKLLADGATEIGGPLPINTDGGLIANGEPIGASGLRQIHELVRQLRGEAGDRQVPGEP
CHHHHHHCCCHHCCCCCEECCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
RVGFGQLYGAPGTAAAMIVST
CCCHHHEECCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]