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The map label for this gene is frc [H]

Identifier: 119867866

GI number: 119867866

Start: 1938805

End: 1940019

Strand: Reverse

Name: frc [H]

Synonym: Mkms_1827

Alternate gene names: 119867866

Gene position: 1940019-1938805 (Counterclockwise)

Preceding gene: 119867868

Following gene: 119867865

Centisome position: 33.81

GC content: 66.5

Gene sequence:

>1215_bases
ATGGAGGGCGTGCGGGTCCTCGAGGTCGCACAGTTCACCTTCGTGCCGGCGGCGGGTGCCATCCTCGCCGACTGGGGTGC
CGACGTCATCAAGGTCGAACACCCCGTGCGCGGTGACACTCAACGCGGTTTCATCAACATGGGCGGATTCCAACTGGATC
CGAACCGGCATCCGCTCATCGAGCACCCCAACCGCGGTAAGCGCAGCGTCGGTATCGACGTGTCGACACCCGACGGCCAG
GAGGTGCTCTACGAGATCGCCAAGACCGCGGACGTGTTCCTGACCAACTACCTGCCCGCACAGCGGCAGAAGAACAAGTT
CGACGTCGAACACATCCGGGCGGCGAACCCGAACATCATCTACGCCCGCGGCAGCGCCTACGGCGACAAGGGTCCCGAAC
GTGACGTGGGCGGTTTCGACGGCACCGCGTTCTGGACGCGCAGCGGGGTGGGTCATGCACTGACCCCCGAGGAGATCGGC
GGCGCGCTGTCGCAGGGCATCCCGGCCTTCGGCGATTCGATCGGCGGGATGAACATCGCCGGCGGGATCTCGGCGGCACT
GTTCCACCGCGAGCGCACCGGCGAAGCGGTCGAACTCGACGTGTCCCTGCTCAGCACCGCCTGGTGGGCGGCCGGCGCCA
GCGTCACGCAGGGCATGGAGACCGGTGAGACGATGCGCTCACTGATGCCCGACTCGGCGAGCCCCTCGGTCAACCCGTTC
CTGGGCAACTACCTGACCTCCGACGGCGGCACGATCAACCTGTGCATCGTCAGTCCGACCGGGTACATCCGCGACGCCTT
CGAACACCTCGGCCTGCCCGAACTGGCCGACGACCCGCGCTTCAACGATGTCATGCCGCTCATCGAGAATGCCCCGGCCG
CAGTGCAATTGATCGCCGACGCGATCCGCAGCAAACCGTTCGACTACTGGCGCCTGCACCTGAAGACGATGAAGGGCCAG
TGGGCGCCGTTCCAGAGCCTGGTCGATCTGGGCACCGACGAGCAGGCCATCGCCAACGACATGATCGTCGAGGTCGAGGC
CAACGACGGCGGCGAACCGTTCAAGGTGGTGCGCGGCCCGGTGCAGTTCAACCACGAACCGCTGGTGACGACCCGCGCCC
CGCAGGCCTCCGAACACACCGAGATCGTGCTCATGGAGTTGGGTCTGGACTGGGACCGCATCGAGGCGCTCAAGGACTCG
GGCGCCATCGCCTGA

Upstream 100 bases:

>100_bases
ATCACAGTTGTTGGTGGCGTAACTGTAACCATTACGGTAACCCAGCACCACGGTGCCTGTCTGCCCCGTCGAGATGTCAG
GAGAGCCAGTGATCAAGGTG

Downstream 100 bases:

>100_bases
TCCCCGCAGCCCGCGAGCCACAGACACTTACCGTAAGCGTTACAGTTGAGATATCATCACCGGCATGAACGATGTCGCGA
TCATCGGTGTGGGGCTGCAT

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MEGVRVLEVAQFTFVPAAGAILADWGADVIKVEHPVRGDTQRGFINMGGFQLDPNRHPLIEHPNRGKRSVGIDVSTPDGQ
EVLYEIAKTADVFLTNYLPAQRQKNKFDVEHIRAANPNIIYARGSAYGDKGPERDVGGFDGTAFWTRSGVGHALTPEEIG
GALSQGIPAFGDSIGGMNIAGGISAALFHRERTGEAVELDVSLLSTAWWAAGASVTQGMETGETMRSLMPDSASPSVNPF
LGNYLTSDGGTINLCIVSPTGYIRDAFEHLGLPELADDPRFNDVMPLIENAPAAVQLIADAIRSKPFDYWRLHLKTMKGQ
WAPFQSLVDLGTDEQAIANDMIVEVEANDGGEPFKVVRGPVQFNHEPLVTTRAPQASEHTEIVLMELGLDWDRIEALKDS
GAIA

Sequences:

>Translated_404_residues
MEGVRVLEVAQFTFVPAAGAILADWGADVIKVEHPVRGDTQRGFINMGGFQLDPNRHPLIEHPNRGKRSVGIDVSTPDGQ
EVLYEIAKTADVFLTNYLPAQRQKNKFDVEHIRAANPNIIYARGSAYGDKGPERDVGGFDGTAFWTRSGVGHALTPEEIG
GALSQGIPAFGDSIGGMNIAGGISAALFHRERTGEAVELDVSLLSTAWWAAGASVTQGMETGETMRSLMPDSASPSVNPF
LGNYLTSDGGTINLCIVSPTGYIRDAFEHLGLPELADDPRFNDVMPLIENAPAAVQLIADAIRSKPFDYWRLHLKTMKGQ
WAPFQSLVDLGTDEQAIANDMIVEVEANDGGEPFKVVRGPVQFNHEPLVTTRAPQASEHTEIVLMELGLDWDRIEALKDS
GAIA
>Mature_404_residues
MEGVRVLEVAQFTFVPAAGAILADWGADVIKVEHPVRGDTQRGFINMGGFQLDPNRHPLIEHPNRGKRSVGIDVSTPDGQ
EVLYEIAKTADVFLTNYLPAQRQKNKFDVEHIRAANPNIIYARGSAYGDKGPERDVGGFDGTAFWTRSGVGHALTPEEIG
GALSQGIPAFGDSIGGMNIAGGISAALFHRERTGEAVELDVSLLSTAWWAAGASVTQGMETGETMRSLMPDSASPSVNPF
LGNYLTSDGGTINLCIVSPTGYIRDAFEHLGLPELADDPRFNDVMPLIENAPAAVQLIADAIRSKPFDYWRLHLKTMKGQ
WAPFQSLVDLGTDEQAIANDMIVEVEANDGGEPFKVVRGPVQFNHEPLVTTRAPQASEHTEIVLMELGLDWDRIEALKDS
GAIA

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=397, Percent_Identity=26.1964735516373, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI300863124, Length=372, Percent_Identity=25.5376344086022, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI42794625, Length=414, Percent_Identity=26.0869565217391, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI266456254, Length=414, Percent_Identity=26.0869565217391, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI300863126, Length=157, Percent_Identity=33.1210191082803, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI266458393, Length=266, Percent_Identity=28.9473684210526, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI266458397, Length=266, Percent_Identity=28.9473684210526, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI87082093, Length=349, Percent_Identity=25.214899713467, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1788717, Length=450, Percent_Identity=25.1111111111111, Blast_Score=92, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24648431, Length=409, Percent_Identity=27.8728606356968, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24585488, Length=417, Percent_Identity=23.9808153477218, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 43657; Mature: 43657

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGVRVLEVAQFTFVPAAGAILADWGADVIKVEHPVRGDTQRGFINMGGFQLDPNRHPLI
CCCCEEEEEEHEEECCCCCCEEECCCCCEEEECCCCCCCCCCCEEECCCEEECCCCCCCC
EHPNRGKRSVGIDVSTPDGQEVLYEIAKTADVFLTNYLPAQRQKNKFDVEHIRAANPNII
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHCCCCCEE
YARGSAYGDKGPERDVGGFDGTAFWTRSGVGHALTPEEIGGALSQGIPAFGDSIGGMNIA
EEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEC
GGISAALFHRERTGEAVELDVSLLSTAWWAAGASVTQGMETGETMRSLMPDSASPSVNPF
CCHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCHHHHCHHHHHHHHHHCCCCCCCCCCCH
LGNYLTSDGGTINLCIVSPTGYIRDAFEHLGLPELADDPRFNDVMPLIENAPAAVQLIAD
HHHHEECCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHH
AIRSKPFDYWRLHLKTMKGQWAPFQSLVDLGTDEQAIANDMIVEVEANDGGEPFKVVRGP
HHHCCCCHHHEEEHHHHCCCCCCHHHHHHCCCCHHHHCCCEEEEEECCCCCCCCEEEECC
VQFNHEPLVTTRAPQASEHTEIVLMELGLDWDRIEALKDSGAIA
HHCCCCCEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MEGVRVLEVAQFTFVPAAGAILADWGADVIKVEHPVRGDTQRGFINMGGFQLDPNRHPLI
CCCCEEEEEEHEEECCCCCCEEECCCCCEEEECCCCCCCCCCCEEECCCEEECCCCCCCC
EHPNRGKRSVGIDVSTPDGQEVLYEIAKTADVFLTNYLPAQRQKNKFDVEHIRAANPNII
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHCCCCCEE
YARGSAYGDKGPERDVGGFDGTAFWTRSGVGHALTPEEIGGALSQGIPAFGDSIGGMNIA
EEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEC
GGISAALFHRERTGEAVELDVSLLSTAWWAAGASVTQGMETGETMRSLMPDSASPSVNPF
CCHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCHHHHCHHHHHHHHHHCCCCCCCCCCCH
LGNYLTSDGGTINLCIVSPTGYIRDAFEHLGLPELADDPRFNDVMPLIENAPAAVQLIAD
HHHHEECCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHH
AIRSKPFDYWRLHLKTMKGQWAPFQSLVDLGTDEQAIANDMIVEVEANDGGEPFKVVRGP
HHHCCCCHHHEEEHHHHCCCCCCHHHHHHCCCCHHHHCCCEEEEEECCCCCCCCEEEECC
VQFNHEPLVTTRAPQASEHTEIVLMELGLDWDRIEALKDSGAIA
HHCCCCCEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]