The gene/protein map for NC_008705 is currently unavailable.
Definition Mycobacterium sp. KMS chromosome, complete genome.
Accession NC_008705
Length 5,737,227

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The map label for this gene is fabG [H]

Identifier: 119867570

GI number: 119867570

Start: 1633826

End: 1634653

Strand: Direct

Name: fabG [H]

Synonym: Mkms_1522

Alternate gene names: 119867570

Gene position: 1633826-1634653 (Clockwise)

Preceding gene: 119867569

Following gene: 119867571

Centisome position: 28.48

GC content: 67.51

Gene sequence:

>828_bases
GTGGCTGCTGGACATCTCGATGGAAAGGTCGCACTGGTCTCGGGATCGGGGCGTGGGATCGGCCGCGCGGTCGCCGAGAA
GCTTGCCGCGGAGGGTGCCCGGGTCGTCATCAACGACCTCGACGCCGAGCCGGCCAAGGAGGTCGTCGCCGCGATCGAAG
CCGCCGGGGGACAGGCCACCGCGTGCGTCGGCAGCGTGACCGATCCCGAATTCGCCGACCGCTTCGTCTCGACCGCCGTC
GACAACTACGGCGGGCTGGACATCATCGTCAACAACGCCGGGTACACCTGGGACAGCGTGATCCAGAAGATGACCGATCA
GCAGTGGAACGACATCATCGACGTGCACCTGACCGCACCGTTCCGGATCCTGCGCGCCGCCCAGCCGGTCATCTCGGGTC
TGGCCAAGAAGGAGAAGGCCGAGAACGGCGTCGCCTCACGCCGCGCAATCGTCAACACGTCGTCGACCTCGGGGCTGCAG
GGCAACCCCGGGCAGGTCAACTACTCCACCGCCAAGGCCGGCCTGATCGGTATGACCAAGACCCTGGCCAAGGAGTGGGG
CCGCTACAACGTCACCGTCAATGCCATCGCCTATGGCGTGATCAACACCCGGCTCACCACGATCACCACCGAGGCGAAGA
CCATCGACGTCGCCGGCCGCGAGATCAAGGTCGGCGTGAACCCGGAGGTGTACGAGGCCGTGACCACCCAGATCGCACTG
GGCCGTGGCGGCAGCGTCGAGGAGGCCGCGGGCGCCGTGTACCTGCTGTGCGCCCCGGAGTCCAGCTACATCACCGCGCA
GACGCTGGTGTGCAGCGGCGGGGCCTGA

Upstream 100 bases:

>100_bases
TAGATCTAAAACGCCACGTCAATTGGTAGTTGACCCAGCGAAGCGCCGAAGTTAAGGTTCACAACAACACGTTGGAATGC
ACTTTGGAGAGGACGCTGTC

Downstream 100 bases:

>100_bases
GAGCCCATGAGCGCTCAGCAGCCGGCCCAGCCGACGTACGAAGAAGTCGACTATCGCTTCGACGACGGTGTCGCGATCAT
CGCGCTCAACGCCCCGCAAC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MAAGHLDGKVALVSGSGRGIGRAVAEKLAAEGARVVINDLDAEPAKEVVAAIEAAGGQATACVGSVTDPEFADRFVSTAV
DNYGGLDIIVNNAGYTWDSVIQKMTDQQWNDIIDVHLTAPFRILRAAQPVISGLAKKEKAENGVASRRAIVNTSSTSGLQ
GNPGQVNYSTAKAGLIGMTKTLAKEWGRYNVTVNAIAYGVINTRLTTITTEAKTIDVAGREIKVGVNPEVYEAVTTQIAL
GRGGSVEEAAGAVYLLCAPESSYITAQTLVCSGGA

Sequences:

>Translated_275_residues
MAAGHLDGKVALVSGSGRGIGRAVAEKLAAEGARVVINDLDAEPAKEVVAAIEAAGGQATACVGSVTDPEFADRFVSTAV
DNYGGLDIIVNNAGYTWDSVIQKMTDQQWNDIIDVHLTAPFRILRAAQPVISGLAKKEKAENGVASRRAIVNTSSTSGLQ
GNPGQVNYSTAKAGLIGMTKTLAKEWGRYNVTVNAIAYGVINTRLTTITTEAKTIDVAGREIKVGVNPEVYEAVTTQIAL
GRGGSVEEAAGAVYLLCAPESSYITAQTLVCSGGA
>Mature_274_residues
AAGHLDGKVALVSGSGRGIGRAVAEKLAAEGARVVINDLDAEPAKEVVAAIEAAGGQATACVGSVTDPEFADRFVSTAVD
NYGGLDIIVNNAGYTWDSVIQKMTDQQWNDIIDVHLTAPFRILRAAQPVISGLAKKEKAENGVASRRAIVNTSSTSGLQG
NPGQVNYSTAKAGLIGMTKTLAKEWGRYNVTVNAIAYGVINTRLTTITTEAKTIDVAGREIKVGVNPEVYEAVTTQIALG
RGGSVEEAAGAVYLLCAPESSYITAQTLVCSGGA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=270, Percent_Identity=32.5925925925926, Blast_Score=130, Evalue=9e-31,
Organism=Homo sapiens, GI4504505, Length=202, Percent_Identity=40.0990099009901, Blast_Score=124, Evalue=7e-29,
Organism=Homo sapiens, GI15277342, Length=279, Percent_Identity=32.258064516129, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI126723750, Length=274, Percent_Identity=28.1021897810219, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI5031737, Length=273, Percent_Identity=26.7399267399267, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI40254992, Length=266, Percent_Identity=30.8270676691729, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI19923817, Length=279, Percent_Identity=27.2401433691756, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI126723191, Length=192, Percent_Identity=31.7708333333333, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI31542939, Length=203, Percent_Identity=32.0197044334975, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI10190704, Length=273, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI4758504, Length=212, Percent_Identity=28.7735849056604, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI33667109, Length=208, Percent_Identity=28.3653846153846, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI224922801, Length=181, Percent_Identity=31.4917127071823, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7705925, Length=274, Percent_Identity=28.1021897810219, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI32455239, Length=203, Percent_Identity=29.5566502463054, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI5031765, Length=203, Percent_Identity=29.5566502463054, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI4503301, Length=281, Percent_Identity=27.7580071174377, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI83715985, Length=187, Percent_Identity=28.3422459893048, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI66933014, Length=272, Percent_Identity=26.1029411764706, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI40254986, Length=204, Percent_Identity=28.4313725490196, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=270, Percent_Identity=35.9259259259259, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI87082100, Length=276, Percent_Identity=28.9855072463768, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI87082160, Length=272, Percent_Identity=30.1470588235294, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787905, Length=269, Percent_Identity=29.368029739777, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1790717, Length=270, Percent_Identity=28.1481481481481, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1789208, Length=277, Percent_Identity=28.158844765343, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI2367175, Length=270, Percent_Identity=30.7407407407407, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789378, Length=275, Percent_Identity=30.1818181818182, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789057, Length=271, Percent_Identity=25.830258302583, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788459, Length=270, Percent_Identity=27.037037037037, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI2367365, Length=271, Percent_Identity=25.4612546125461, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=220, Percent_Identity=38.6363636363636, Blast_Score=141, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17555706, Length=269, Percent_Identity=33.8289962825279, Blast_Score=138, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI25147288, Length=272, Percent_Identity=37.1323529411765, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17561402, Length=272, Percent_Identity=29.4117647058824, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17560676, Length=279, Percent_Identity=30.4659498207885, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17562910, Length=280, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17544670, Length=294, Percent_Identity=27.891156462585, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=275, Percent_Identity=31.2727272727273, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17538182, Length=210, Percent_Identity=31.9047619047619, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=276, Percent_Identity=29.7101449275362, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=203, Percent_Identity=31.5270935960591, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=270, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=281, Percent_Identity=27.0462633451957, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=203, Percent_Identity=33.4975369458128, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=274, Percent_Identity=29.1970802919708, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=282, Percent_Identity=27.6595744680851, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=278, Percent_Identity=29.4964028776978, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=279, Percent_Identity=29.3906810035842, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=279, Percent_Identity=29.3906810035842, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=271, Percent_Identity=26.5682656826568, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=277, Percent_Identity=28.8808664259928, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=281, Percent_Identity=27.7580071174377, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=283, Percent_Identity=28.6219081272085, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=279, Percent_Identity=27.5985663082437, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=177, Percent_Identity=27.683615819209, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=178, Percent_Identity=28.6516853932584, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=178, Percent_Identity=28.6516853932584, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=263, Percent_Identity=26.9961977186312, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=279, Percent_Identity=27.9569892473118, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=282, Percent_Identity=26.9503546099291, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=273, Percent_Identity=29.3040293040293, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=201, Percent_Identity=38.3084577114428, Blast_Score=130, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6324126, Length=273, Percent_Identity=25.6410256410256, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI18859837, Length=254, Percent_Identity=37.4015748031496, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24639444, Length=276, Percent_Identity=32.6086956521739, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI21355319, Length=272, Percent_Identity=29.4117647058824, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24644339, Length=272, Percent_Identity=30.1470588235294, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28571526, Length=271, Percent_Identity=29.1512915129151, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17737361, Length=225, Percent_Identity=29.3333333333333, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357041, Length=274, Percent_Identity=28.1021897810219, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI23397609, Length=272, Percent_Identity=27.2058823529412, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24643142, Length=278, Percent_Identity=25.8992805755396, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21357673, Length=203, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24644337, Length=270, Percent_Identity=27.4074074074074, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28468; Mature: 28337

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MAAGHLDGKVALVSGSGRGIGRAVAEKLAAEGARVVINDLDAEPAKEVVAAIEAAGGQAT
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCEE
ACVGSVTDPEFADRFVSTAVDNYGGLDIIVNNAGYTWDSVIQKMTDQQWNDIIDVHLTAP
EEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCH
FRILRAAQPVISGLAKKEKAENGVASRRAIVNTSSTSGLQGNPGQVNYSTAKAGLIGMTK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEECCCCCCCCCCCCEEEEHHHHCCHHHHHH
TLAKEWGRYNVTVNAIAYGVINTRLTTITTEAKTIDVAGREIKVGVNPEVYEAVTTQIAL
HHHHHCCCEEEEEHHEEEEEHHCEEEEEEECCEEEEECCCEEEECCCCHHHHHHHHHEEE
GRGGSVEEAAGAVYLLCAPESSYITAQTLVCSGGA
CCCCCCHHCCCEEEEEECCCCCEEEEEEEEECCCC
>Mature Secondary Structure 
AAGHLDGKVALVSGSGRGIGRAVAEKLAAEGARVVINDLDAEPAKEVVAAIEAAGGQAT
CCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCEE
ACVGSVTDPEFADRFVSTAVDNYGGLDIIVNNAGYTWDSVIQKMTDQQWNDIIDVHLTAP
EEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCH
FRILRAAQPVISGLAKKEKAENGVASRRAIVNTSSTSGLQGNPGQVNYSTAKAGLIGMTK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEECCCCCCCCCCCCEEEEHHHHCCHHHHHH
TLAKEWGRYNVTVNAIAYGVINTRLTTITTEAKTIDVAGREIKVGVNPEVYEAVTTQIAL
HHHHHCCCEEEEEHHEEEEEHHCEEEEEEECCEEEEECCCEEEECCCCHHHHHHHHHEEE
GRGGSVEEAAGAVYLLCAPESSYITAQTLVCSGGA
CCCCCCHHCCCEEEEEECCCCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]