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The map label for this gene is yycF [H]

Identifier: 119867507

GI number: 119867507

Start: 1570387

End: 1571184

Strand: Reverse

Name: yycF [H]

Synonym: Mkms_1457

Alternate gene names: 119867507

Gene position: 1571184-1570387 (Counterclockwise)

Preceding gene: 119867508

Following gene: 119867506

Centisome position: 27.39

GC content: 63.66

Gene sequence:

>798_bases
ATGGCGGCGTCGTCCACCACGACAACCTCTCCCGCGGGCACCATCATTGCTATGGACCATTCCCCCGCTACGCCCTCCGA
GCACGCGAGGGGATATCGCGCGCTGGTCGTCGACGACGAAGCGCCCCTGGCCGAAGTGGTGGCCAGCTACCTGGAGCGTG
AGCACTTCGAGGCCATCGTCACCGGCAACGGCGCCGACGCAATCACCATCGCCCGCGAACTCGACCCCGACGTCGTCATC
CTCGACATCGGACTGCCCGGCATCGACGGGTTAGAGGTGTGCCGGCAATTACGCACCTTCTCCGACGCCTACGTCGTCAT
GCTCACCGCCCGCGACACCGAAATGGACACCATTCTCGGCCTCACCGTCGGTGCCGACGACTACATCACCAAACCGTTCA
GCCCACGAGAACTCGTGGCACGAATCCGCGCGATGCTGCGGCGACCCCGCATCCAGCAATCAGCCGCTGCTGCCACCGAA
CGAGAAGCAGTACCACCGCGGCGGTTCGGAGCGCTCATTATCGACGTCGCCGCACGCGAAGTCCACATCGACGATGAACC
GATCCTGTTGACACGTACCGAATTCGACATCCTCGAAGCACTGTCCGCGCGTCCCGGAATAGTCTTGAGCCGTCGCCAAC
TCCTAGAAATTGTCCGCGACGGGCCGTGGGTCGGCAACGAGCACCTCGTCGACGTCCATATCGGGCACCTACGACGCAAA
CTCGGCGACGACGCCGCCAACCCCCGCTACATCACGACGGTCCGAGGTGTCGGATACCGAATGGGAACCGGTCAATGA

Upstream 100 bases:

>100_bases
CCATCGCACTGAGCGCTCCCTTCGTCGACCACCAGCCTCACCCAGATGCGATGCGCAACCGATATGAGTCCGATAAAGAT
CTGCTGAAGATTTCAGCGTC

Downstream 100 bases:

>100_bases
GCACCGCCGCGCCAGCATCACCGACCAGGGGTCCACGATGGCGCCGCCCCGGCATCGGGCTGCGCCTGCTAGCCGCCCAA
GCCATCGTGTTGGCTGCCGG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MAASSTTTTSPAGTIIAMDHSPATPSEHARGYRALVVDDEAPLAEVVASYLEREHFEAIVTGNGADAITIARELDPDVVI
LDIGLPGIDGLEVCRQLRTFSDAYVVMLTARDTEMDTILGLTVGADDYITKPFSPRELVARIRAMLRRPRIQQSAAAATE
REAVPPRRFGALIIDVAAREVHIDDEPILLTRTEFDILEALSARPGIVLSRRQLLEIVRDGPWVGNEHLVDVHIGHLRRK
LGDDAANPRYITTVRGVGYRMGTGQ

Sequences:

>Translated_265_residues
MAASSTTTTSPAGTIIAMDHSPATPSEHARGYRALVVDDEAPLAEVVASYLEREHFEAIVTGNGADAITIARELDPDVVI
LDIGLPGIDGLEVCRQLRTFSDAYVVMLTARDTEMDTILGLTVGADDYITKPFSPRELVARIRAMLRRPRIQQSAAAATE
REAVPPRRFGALIIDVAAREVHIDDEPILLTRTEFDILEALSARPGIVLSRRQLLEIVRDGPWVGNEHLVDVHIGHLRRK
LGDDAANPRYITTVRGVGYRMGTGQ
>Mature_264_residues
AASSTTTTSPAGTIIAMDHSPATPSEHARGYRALVVDDEAPLAEVVASYLEREHFEAIVTGNGADAITIARELDPDVVIL
DIGLPGIDGLEVCRQLRTFSDAYVVMLTARDTEMDTILGLTVGADDYITKPFSPRELVARIRAMLRRPRIQQSAAAATER
EAVPPRRFGALIIDVAAREVHIDDEPILLTRTEFDILEALSARPGIVLSRRQLLEIVRDGPWVGNEHLVDVHIGHLRRKL
GDDAANPRYITTVRGVGYRMGTGQ

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=41.304347826087, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=40.7894736842105, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=41.0480349344978, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=38.7665198237885, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=40.5982905982906, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=35.9649122807018, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=35.8078602620087, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=35.8078602620087, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=35.6521739130435, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787375, Length=238, Percent_Identity=35.2941176470588, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=34.3478260869565, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=33.7662337662338, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=34.8017621145374, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1790552, Length=237, Percent_Identity=33.7552742616034, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1788521, Length=215, Percent_Identity=29.3023255813954, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=32.7102803738318, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28964; Mature: 28833

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASSTTTTSPAGTIIAMDHSPATPSEHARGYRALVVDDEAPLAEVVASYLEREHFEAIV
CCCCCCCCCCCCCEEEEECCCCCCCHHHCCCEEEEEEECCCCHHHHHHHHHHHHHEEEEE
TGNGADAITIARELDPDVVILDIGLPGIDGLEVCRQLRTFSDAYVVMLTARDTEMDTILG
ECCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCEEEE
LTVGADDYITKPFSPRELVARIRAMLRRPRIQQSAAAATEREAVPPRRFGALIIDVAARE
EEECCCHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHCEEEEEEEHEE
VHIDDEPILLTRTEFDILEALSARPGIVLSRRQLLEIVRDGPWVGNEHLVDVHIGHLRRK
EEECCCCEEEEECHHHHHHHHCCCCCEEECHHHHHHHHHCCCCCCCCEEEEEEHHHHHHH
LGDDAANPRYITTVRGVGYRMGTGQ
HCCCCCCCEEEEEEECCCEECCCCC
>Mature Secondary Structure 
AASSTTTTSPAGTIIAMDHSPATPSEHARGYRALVVDDEAPLAEVVASYLEREHFEAIV
CCCCCCCCCCCCEEEEECCCCCCCHHHCCCEEEEEEECCCCHHHHHHHHHHHHHEEEEE
TGNGADAITIARELDPDVVILDIGLPGIDGLEVCRQLRTFSDAYVVMLTARDTEMDTILG
ECCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCEEEE
LTVGADDYITKPFSPRELVARIRAMLRRPRIQQSAAAATEREAVPPRRFGALIIDVAARE
EEECCCHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHCEEEEEEEHEE
VHIDDEPILLTRTEFDILEALSARPGIVLSRRQLLEIVRDGPWVGNEHLVDVHIGHLRRK
EEECCCCEEEEECHHHHHHHHCCCCCEEECHHHHHHHHHCCCCCCCCEEEEEEHHHHHHH
LGDDAANPRYITTVRGVGYRMGTGQ
HCCCCCCCEEEEEEECCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]