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The map label for this gene is baeS [H]

Identifier: 119867506

GI number: 119867506

Start: 1569206

End: 1570390

Strand: Reverse

Name: baeS [H]

Synonym: Mkms_1456

Alternate gene names: 119867506

Gene position: 1570390-1569206 (Counterclockwise)

Preceding gene: 119867507

Following gene: 119867504

Centisome position: 27.37

GC content: 65.15

Gene sequence:

>1185_bases
ATGAGCACCGCCGCGCCAGCATCACCGACCAGGGGTCCACGATGGCGCCGCCCCGGCATCGGGCTGCGCCTGCTAGCCGC
CCAAGCCATCGTGTTGGCTGCCGGAGCAGCCACCACGTCGATCGTCGCCGCCGTCGTCGGGCCGCCCCTGTTTCGGGAAC
ACCTACATATGGCCGGAGTGGCCGTCGACTCCCTGGAAGAAATCCACGCTGAAGAGGCCTATGGCTACGCCACAGTTATC
TCCATCGGCGGAGCGTTGGCCGTGTCAGCCCTAGCAGCGCTGGCCGTCAGCTTTTACGTCAGCCGGCGCCTACAGCGCTC
CGTCACCGAAGTAGCCTCGGCAGCCCGAGCAGTCGCCGAAGGACATTACGACATCCGAGTATCGCCGCCACGCCTCGGGG
ACGACTTCGACTCCCTGGCCGTAGCGTTCAACAAAATGGCGTCGCGCCTACAAGCAGTCGACACCACCCGACAGCAACTG
TTCGGAGACCTCGCGCACGAAATTCGCACGCCCGTCGCAGTTCTCGACGCCTACATCGAGGCACTCGAAGACGGCGTGCG
CACGCTGACACCTCAAACAGCGGCGATGCTGCGCGACCAAACCAGACGACTCGTACGGTTCTCCGGCGACGTCGCGGCGC
TGGCACGGGCCGAAGAAAGCGCTGTCTCCATGGCCTACAACGTCATCGACGCCGAAACTCTAGCGCGAGGCTGCCTCGCC
GCAGCCCAGACACGGTACGACACCAAAGGCGTCGCCCTGGAATTGAGCACCGCGCAGAACCTACCGCCACTATGGGCCGA
CGAGCAGCGACTCTCTCAGGTGATCGGCAACCTGCTCGACAACGCGTTACGGCACACCCCCACCGGCGGCACTGTGCGGC
TTGAATGCTCCTACAACCAGAATCAACTATGGATACGAGTCGCCGACAACGGCGAGGGCATCGGCATCGACCATCTCCCC
CGGGTTTTCGAACGCTTCTACCGCGCAGACTCAGCCCGCGACCGCCAACATGGCGGCGCCGGACTTGGACTGGCCATCGC
CAAAGCGCTCATCGAAGCCCACGGCGGCGACATCTCTGTTTCGAGCGACGGGCCCGGGACCGGTGCGGCATTTACGGTCA
AACTGCCCATCGCGCAACACCACAACAGTGCCGCGGCGGGGCCGGCGAGGCCAGTGCGCGCCTGA

Upstream 100 bases:

>100_bases
TCCATATCGGGCACCTACGACGCAAACTCGGCGACGACGCCGCCAACCCCCGCTACATCACGACGGTCCGAGGTGTCGGA
TACCGAATGGGAACCGGTCA

Downstream 100 bases:

>100_bases
CCTCGCCGCACCTCTTTAGCCGTTTAACATCCCCTGCATCGTGTCGATCTCCTTCTGCTGAGAGGACACGATATTGCGCG
CCATTTCCACAGCCTCCGAG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MSTAAPASPTRGPRWRRPGIGLRLLAAQAIVLAAGAATTSIVAAVVGPPLFREHLHMAGVAVDSLEEIHAEEAYGYATVI
SIGGALAVSALAALAVSFYVSRRLQRSVTEVASAARAVAEGHYDIRVSPPRLGDDFDSLAVAFNKMASRLQAVDTTRQQL
FGDLAHEIRTPVAVLDAYIEALEDGVRTLTPQTAAMLRDQTRRLVRFSGDVAALARAEESAVSMAYNVIDAETLARGCLA
AAQTRYDTKGVALELSTAQNLPPLWADEQRLSQVIGNLLDNALRHTPTGGTVRLECSYNQNQLWIRVADNGEGIGIDHLP
RVFERFYRADSARDRQHGGAGLGLAIAKALIEAHGGDISVSSDGPGTGAAFTVKLPIAQHHNSAAAGPARPVRA

Sequences:

>Translated_394_residues
MSTAAPASPTRGPRWRRPGIGLRLLAAQAIVLAAGAATTSIVAAVVGPPLFREHLHMAGVAVDSLEEIHAEEAYGYATVI
SIGGALAVSALAALAVSFYVSRRLQRSVTEVASAARAVAEGHYDIRVSPPRLGDDFDSLAVAFNKMASRLQAVDTTRQQL
FGDLAHEIRTPVAVLDAYIEALEDGVRTLTPQTAAMLRDQTRRLVRFSGDVAALARAEESAVSMAYNVIDAETLARGCLA
AAQTRYDTKGVALELSTAQNLPPLWADEQRLSQVIGNLLDNALRHTPTGGTVRLECSYNQNQLWIRVADNGEGIGIDHLP
RVFERFYRADSARDRQHGGAGLGLAIAKALIEAHGGDISVSSDGPGTGAAFTVKLPIAQHHNSAAAGPARPVRA
>Mature_393_residues
STAAPASPTRGPRWRRPGIGLRLLAAQAIVLAAGAATTSIVAAVVGPPLFREHLHMAGVAVDSLEEIHAEEAYGYATVIS
IGGALAVSALAALAVSFYVSRRLQRSVTEVASAARAVAEGHYDIRVSPPRLGDDFDSLAVAFNKMASRLQAVDTTRQQLF
GDLAHEIRTPVAVLDAYIEALEDGVRTLTPQTAAMLRDQTRRLVRFSGDVAALARAEESAVSMAYNVIDAETLARGCLAA
AQTRYDTKGVALELSTAQNLPPLWADEQRLSQVIGNLLDNALRHTPTGGTVRLECSYNQNQLWIRVADNGEGIGIDHLPR
VFERFYRADSARDRQHGGAGLGLAIAKALIEAHGGDISVSSDGPGTGAAFTVKLPIAQHHNSAAAGPARPVRA

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=270, Percent_Identity=34.0740740740741, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1786783, Length=271, Percent_Identity=29.1512915129151, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786600, Length=284, Percent_Identity=30.2816901408451, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1790346, Length=274, Percent_Identity=27.7372262773723, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787894, Length=300, Percent_Identity=29.3333333333333, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=28.5123966942149, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788549, Length=233, Percent_Identity=30.0429184549356, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788713, Length=271, Percent_Identity=28.0442804428044, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789149, Length=358, Percent_Identity=26.536312849162, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=28.6363636363636, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788279, Length=244, Percent_Identity=25.4098360655738, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790861, Length=296, Percent_Identity=26.6891891891892, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87081816, Length=226, Percent_Identity=29.646017699115, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=25.9574468085106, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI48994928, Length=223, Percent_Identity=26.457399103139, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87082128, Length=243, Percent_Identity=26.7489711934156, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=292, Percent_Identity=23.6301369863014, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790551, Length=302, Percent_Identity=24.8344370860927, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787374, Length=255, Percent_Identity=25.4901960784314, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41699; Mature: 41567

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAAPASPTRGPRWRRPGIGLRLLAAQAIVLAAGAATTSIVAAVVGPPLFREHLHMAGV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHH
AVDSLEEIHAEEAYGYATVISIGGALAVSALAALAVSFYVSRRLQRSVTEVASAARAVAE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GHYDIRVSPPRLGDDFDSLAVAFNKMASRLQAVDTTRQQLFGDLAHEIRTPVAVLDAYIE
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
ALEDGVRTLTPQTAAMLRDQTRRLVRFSGDVAALARAEESAVSMAYNVIDAETLARGCLA
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAQTRYDTKGVALELSTAQNLPPLWADEQRLSQVIGNLLDNALRHTPTGGTVRLECSYNQ
HHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
NQLWIRVADNGEGIGIDHLPRVFERFYRADSARDRQHGGAGLGLAIAKALIEAHGGDISV
CEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHCCCCEEE
SSDGPGTGAAFTVKLPIAQHHNSAAAGPARPVRA
CCCCCCCCCEEEEEECHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STAAPASPTRGPRWRRPGIGLRLLAAQAIVLAAGAATTSIVAAVVGPPLFREHLHMAGV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHH
AVDSLEEIHAEEAYGYATVISIGGALAVSALAALAVSFYVSRRLQRSVTEVASAARAVAE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GHYDIRVSPPRLGDDFDSLAVAFNKMASRLQAVDTTRQQLFGDLAHEIRTPVAVLDAYIE
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
ALEDGVRTLTPQTAAMLRDQTRRLVRFSGDVAALARAEESAVSMAYNVIDAETLARGCLA
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAQTRYDTKGVALELSTAQNLPPLWADEQRLSQVIGNLLDNALRHTPTGGTVRLECSYNQ
HHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
NQLWIRVADNGEGIGIDHLPRVFERFYRADSARDRQHGGAGLGLAIAKALIEAHGGDISV
CEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHCCCCEEE
SSDGPGTGAAFTVKLPIAQHHNSAAAGPARPVRA
CCCCCCCCCEEEEEECHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]