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The map label for this gene is iap [H]

Identifier: 119867508

GI number: 119867508

Start: 1571507

End: 1572910

Strand: Reverse

Name: iap [H]

Synonym: Mkms_1458

Alternate gene names: 119867508

Gene position: 1572910-1571507 (Counterclockwise)

Preceding gene: 119867515

Following gene: 119867507

Centisome position: 27.42

GC content: 65.53

Gene sequence:

>1404_bases
ATGCGGCGCTTCACTTCACTGCTCGGCATAGCAGCAATCACAGTGACACTGCCCGTCAACGCCACCGGCGTCGCGACAGC
CACCCACGAAACCAGGCCATCGCCCAACACCGACCTGCCCACCCTCGTCGCGTCCGTCGCCGAGGCCAATCAGCGAGTGG
CCGACATCGGCGCTGATATTCAGAGCAAGCAGGAGGGCTTCAACAAAGCCCTGGTCGACACAGCCGCTGCACGCGACATT
CTCGCGACCAGACAGCAAGAACTCACCGCCAGCGAGCAGGCGCTCACCGCCAGTCAGACCGACATCGACAACGCCCAATC
CCGCTTCGACCAGTTCGCCGCATCGATGTACATGAACGGCCCTTCACGCGCGCTACCGCTGGCCCGCAGCCCCGAAGAGA
TCCTCGGCGCCGCCGCCACCGAGCAGACACTTACCCTCAGCTTCCGCCAGGCCGAAGACAACCTTCACCGCACGCAAACC
GAACGCGCCAACAAGGTTGCGGCCGCCCAGGCGGCCCGCCTACGCGCCGATGAGGCCGCCGCGGAAGCGCAACGACGACA
AGATGCAGCGGTCGCCGAGCTCACCGCAGTACAGCAGGCGTTCGCCAGCCAACAGACCCAGCTGAACACCATTGTTGCTC
AACGCGACTCCGCCCGGGCGCGACTGAACGAAGCCCGGCCGACCACGAGGGCCACCGCCCCGCCCTCACCGGGCCGCGCT
CAACCCGACTCCGCTCCGCCTCCCACCCAGTGGGACAGCGCCACACCGCCTAGTGGCCCCGACGCCGGCCTCTGGGACAC
CACGTTGCCGATGGTGCCCAGCGCCAACGTCGCCGGCGACCCGATCGCCATCATCAACGCTGTCCTGAAGATCATGGCCA
CCTCTGGCCAGTTGACCGCCGACATGGGACGCAAATTCCTGACCAAGCTCGGCATCCTCTCCCCCGCATCCGCCGCCGCT
GACCCTGGCATCACCAACGGACGAATCCCCCGCGTCTACGGCCAGCAGGCCTCCGAATTGGTGATCCGCCGCGCCATGTC
GCAGTTAGGCGTGCCGTACTCCTGGGGTGGCGGCAATGCCAATGGTCCCGCTCGGGGCATCGACCAGGGAGCCAACACCG
TGGGCTTCGACTGTTCGGGACTCATGCTGTATGCGTTCGCGGGAGTAGGAATCAAGCTCGATCACTACTCCGGATCGCAG
TACAACGCCGGCCGCAAGATCCCGTCTGCACAGATGCGCCGCGGCGACCTCATCTTCTACGGTCCCAACGCAAGCCAACA
CGAGGCGATGTACCTCGGCAACGGCATGATGATCGAAGCTCCCTACACCGGCTCGGTCGTCAAGATATCCCCCGTGCGCT
CCTCCGGCATGACGCCCTACGTCACCCGCTTAATCGAGTACTGA

Upstream 100 bases:

>100_bases
GCGCTACGTACGTTTGCGGTCGTAGATCGGGCAACCAGTGCCCACACCGAGCGACCTCTGACATGGCGAATGAAGCGCAG
CCCCGGTTCAGGAGATTGCG

Downstream 100 bases:

>100_bases
AAGTCCACAGAACAGAGCCGATGAGCGGATTCAGTCGAGCTTTGAGGGACCGCTGTTGACGCTCTGATTCACATCGTCTG
CACGCCGAGCGGCGCGCGAC

Product: NLP/P60 protein

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MRRFTSLLGIAAITVTLPVNATGVATATHETRPSPNTDLPTLVASVAEANQRVADIGADIQSKQEGFNKALVDTAAARDI
LATRQQELTASEQALTASQTDIDNAQSRFDQFAASMYMNGPSRALPLARSPEEILGAAATEQTLTLSFRQAEDNLHRTQT
ERANKVAAAQAARLRADEAAAEAQRRQDAAVAELTAVQQAFASQQTQLNTIVAQRDSARARLNEARPTTRATAPPSPGRA
QPDSAPPPTQWDSATPPSGPDAGLWDTTLPMVPSANVAGDPIAIINAVLKIMATSGQLTADMGRKFLTKLGILSPASAAA
DPGITNGRIPRVYGQQASELVIRRAMSQLGVPYSWGGGNANGPARGIDQGANTVGFDCSGLMLYAFAGVGIKLDHYSGSQ
YNAGRKIPSAQMRRGDLIFYGPNASQHEAMYLGNGMMIEAPYTGSVVKISPVRSSGMTPYVTRLIEY

Sequences:

>Translated_467_residues
MRRFTSLLGIAAITVTLPVNATGVATATHETRPSPNTDLPTLVASVAEANQRVADIGADIQSKQEGFNKALVDTAAARDI
LATRQQELTASEQALTASQTDIDNAQSRFDQFAASMYMNGPSRALPLARSPEEILGAAATEQTLTLSFRQAEDNLHRTQT
ERANKVAAAQAARLRADEAAAEAQRRQDAAVAELTAVQQAFASQQTQLNTIVAQRDSARARLNEARPTTRATAPPSPGRA
QPDSAPPPTQWDSATPPSGPDAGLWDTTLPMVPSANVAGDPIAIINAVLKIMATSGQLTADMGRKFLTKLGILSPASAAA
DPGITNGRIPRVYGQQASELVIRRAMSQLGVPYSWGGGNANGPARGIDQGANTVGFDCSGLMLYAFAGVGIKLDHYSGSQ
YNAGRKIPSAQMRRGDLIFYGPNASQHEAMYLGNGMMIEAPYTGSVVKISPVRSSGMTPYVTRLIEY
>Mature_467_residues
MRRFTSLLGIAAITVTLPVNATGVATATHETRPSPNTDLPTLVASVAEANQRVADIGADIQSKQEGFNKALVDTAAARDI
LATRQQELTASEQALTASQTDIDNAQSRFDQFAASMYMNGPSRALPLARSPEEILGAAATEQTLTLSFRQAEDNLHRTQT
ERANKVAAAQAARLRADEAAAEAQRRQDAAVAELTAVQQAFASQQTQLNTIVAQRDSARARLNEARPTTRATAPPSPGRA
QPDSAPPPTQWDSATPPSGPDAGLWDTTLPMVPSANVAGDPIAIINAVLKIMATSGQLTADMGRKFLTKLGILSPASAAA
DPGITNGRIPRVYGQQASELVIRRAMSQLGVPYSWGGGNANGPARGIDQGANTVGFDCSGLMLYAFAGVGIKLDHYSGSQ
YNAGRKIPSAQMRRGDLIFYGPNASQHEAMYLGNGMMIEAPYTGSVVKISPVRSSGMTPYVTRLIEY

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1786421, Length=119, Percent_Identity=35.2941176470588, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1787944, Length=124, Percent_Identity=30.6451612903226, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 49374; Mature: 49374

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRFTSLLGIAAITVTLPVNATGVATATHETRPSPNTDLPTLVASVAEANQRVADIGADI
CCHHHHHHHHEEEEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCH
QSKQEGFNKALVDTAAARDILATRQQELTASEQALTASQTDIDNAQSRFDQFAASMYMNG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
PSRALPLARSPEEILGAAATEQTLTLSFRQAEDNLHRTQTERANKVAAAQAARLRADEAA
CCCCCCCCCCHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAQRRQDAAVAELTAVQQAFASQQTQLNTIVAQRDSARARLNEARPTTRATAPPSPGRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCC
QPDSAPPPTQWDSATPPSGPDAGLWDTTLPMVPSANVAGDPIAIINAVLKIMATSGQLTA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
DMGRKFLTKLGILSPASAAADPGITNGRIPRVYGQQASELVIRRAMSQLGVPYSWGGGNA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCC
NGPARGIDQGANTVGFDCSGLMLYAFAGVGIKLDHYSGSQYNAGRKIPSAQMRRGDLIFY
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHCCCCEEEE
GPNASQHEAMYLGNGMMIEAPYTGSVVKISPVRSSGMTPYVTRLIEY
CCCCCCCCEEEECCCEEEECCCCCCEEEEECCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MRRFTSLLGIAAITVTLPVNATGVATATHETRPSPNTDLPTLVASVAEANQRVADIGADI
CCHHHHHHHHEEEEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCH
QSKQEGFNKALVDTAAARDILATRQQELTASEQALTASQTDIDNAQSRFDQFAASMYMNG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
PSRALPLARSPEEILGAAATEQTLTLSFRQAEDNLHRTQTERANKVAAAQAARLRADEAA
CCCCCCCCCCHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAQRRQDAAVAELTAVQQAFASQQTQLNTIVAQRDSARARLNEARPTTRATAPPSPGRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCC
QPDSAPPPTQWDSATPPSGPDAGLWDTTLPMVPSANVAGDPIAIINAVLKIMATSGQLTA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
DMGRKFLTKLGILSPASAAADPGITNGRIPRVYGQQASELVIRRAMSQLGVPYSWGGGNA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCC
NGPARGIDQGANTVGFDCSGLMLYAFAGVGIKLDHYSGSQYNAGRKIPSAQMRRGDLIFY
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHCCCCEEEE
GPNASQHEAMYLGNGMMIEAPYTGSVVKISPVRSSGMTPYVTRLIEY
CCCCCCCCEEEECCCEEEECCCCCCEEEEECCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2111287; 1459966; 11679669 [H]