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The map label for this gene is ugd [H]

Identifier: 119897367

GI number: 119897367

Start: 1159107

End: 1160429

Strand: Direct

Name: ugd [H]

Synonym: azo1076

Alternate gene names: 119897367

Gene position: 1159107-1160429 (Clockwise)

Preceding gene: 119897366

Following gene: 119897368

Centisome position: 26.49

GC content: 64.63

Gene sequence:

>1323_bases
ATGAAAGTTACGGTAGTCGGAACCGGTTATGTCGGTCTGGTGAGCGGCGCTTGTCTTGCCGATGTGGGCAATGACGTACT
GTGCCTGGATGTCGACCCGGACAAGATCCGCATCCTCGAGGAGGGCGGCATCCCGATTCACGAGCCGGGCTTGCTCGACG
TCGTCCGGCGCAACGTTGCGGCGGGGCGCCTGTCCTTTACGACGGATGTCGAGCGCGCCGCGCGGCACGGCGTCATACAG
TTCATCGCGGTCGGGACGCCGCCGGACGAGGATGGCTCGGCCGACCTGCAGTACGTGCTCGCGGCCGCCCGCAACATCGG
TCGCCATATGGACGGCTACCGCGTGATTGTGGACAAGTCGACCGTTCCGGTGGGCACGGGTGACAAGGTGCGGGCGGCGG
TGGCCGAGGAACTTGTCGTGCGTGGCAGCACGCTCGCGTACAGCGTGGTGTCCAACCCGGAGTTCCTGAAAGAAGGCGCC
GCAGTAGAGGACTTCATGCGTCCGGACCGGATCATCGTCGGCGCCGATGACGAGCGCGCGGTCGAGCTGATGCGGCAACT
CTACGGCCCGTTCCAGCGCAACCACGAAAAGCTGCTGGTGATGGACGTGCGTAGCGCGGAACTCACCAAGTACGCGGCCA
ACGCGATGCTGGCCACCCGCATCAGCTTCATGAACGAACTTGCCAATCTTGCCGAAACCCTGGGGGCTGACATTGAACTG
GTTCGTCAGGGCATCGGCTCGGACCCCCGTATCGGGTGGCACTTCCTGTATGCCGGCTGCGGCTACGGCGGTTCCTGCTT
CCCCAAGGACGTGAAGGCGCTGGTGCGTACCGGCGCGGAGCATGGGCACGACCTTTTGCTGTTGAATGCGGTCGAAGCGG
TAAACGATGCCCAGAAGTTGCGTCTGGTCGACAAAGTCGTTTCGCGTTTTGGTGAAAATCTGGCCGGGCGCCGGTTTGCG
GTGTGGGGCCTGGCGTTCAAGCCCAATACCGATGACATGCGCGAAGCCCCCAGCCGCGTGGTGCTGGGTGAGTTGCTGGG
GCGCGGCGCTTCGGTCTGCGTCTACGATCCGGTCGCCATGGACGAGGCGCGGCGCATCTTCGGTGTCGATGCGCGCCTGA
GCTACGCAGAGCGCCCGATGGATGCGCTCGAAGCGGCGGACGCGCTGGTCATCGTGACGGAGTGGAAGGAGTTCCGCAGC
CCCGACTTCGAGCGTATCCGAGCGCTGCTCAAGCAGCCGGTGATCTTCGACGGCCGCAACATGTACGACCCCGCGGTCCT
GCGCAGCGAGGGGATCGAGTATTTCGGGATGGGGCGCCGCTGA

Upstream 100 bases:

>100_bases
GGGCAGGGGCACGGGTGAGTCTGTCATCGTCTCGCTTCAATATCGCAGGGCGGGCGCGGACGGACCGGGCCGGCGGAATC
CAATCTGAATCGGGGGTTGC

Downstream 100 bases:

>100_bases
CGGCGTCTTGTTCCGGATGCGACATTGGTTGGGGATTGCAGCGGCTGCGACAGTCGGCAGCCCTGGCCTTCCGTAGCAGT
GCGGGAACGAGTGCCTGGCG

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MKVTVVGTGYVGLVSGACLADVGNDVLCLDVDPDKIRILEEGGIPIHEPGLLDVVRRNVAAGRLSFTTDVERAARHGVIQ
FIAVGTPPDEDGSADLQYVLAAARNIGRHMDGYRVIVDKSTVPVGTGDKVRAAVAEELVVRGSTLAYSVVSNPEFLKEGA
AVEDFMRPDRIIVGADDERAVELMRQLYGPFQRNHEKLLVMDVRSAELTKYAANAMLATRISFMNELANLAETLGADIEL
VRQGIGSDPRIGWHFLYAGCGYGGSCFPKDVKALVRTGAEHGHDLLLLNAVEAVNDAQKLRLVDKVVSRFGENLAGRRFA
VWGLAFKPNTDDMREAPSRVVLGELLGRGASVCVYDPVAMDEARRIFGVDARLSYAERPMDALEAADALVIVTEWKEFRS
PDFERIRALLKQPVIFDGRNMYDPAVLRSEGIEYFGMGRR

Sequences:

>Translated_440_residues
MKVTVVGTGYVGLVSGACLADVGNDVLCLDVDPDKIRILEEGGIPIHEPGLLDVVRRNVAAGRLSFTTDVERAARHGVIQ
FIAVGTPPDEDGSADLQYVLAAARNIGRHMDGYRVIVDKSTVPVGTGDKVRAAVAEELVVRGSTLAYSVVSNPEFLKEGA
AVEDFMRPDRIIVGADDERAVELMRQLYGPFQRNHEKLLVMDVRSAELTKYAANAMLATRISFMNELANLAETLGADIEL
VRQGIGSDPRIGWHFLYAGCGYGGSCFPKDVKALVRTGAEHGHDLLLLNAVEAVNDAQKLRLVDKVVSRFGENLAGRRFA
VWGLAFKPNTDDMREAPSRVVLGELLGRGASVCVYDPVAMDEARRIFGVDARLSYAERPMDALEAADALVIVTEWKEFRS
PDFERIRALLKQPVIFDGRNMYDPAVLRSEGIEYFGMGRR
>Mature_440_residues
MKVTVVGTGYVGLVSGACLADVGNDVLCLDVDPDKIRILEEGGIPIHEPGLLDVVRRNVAAGRLSFTTDVERAARHGVIQ
FIAVGTPPDEDGSADLQYVLAAARNIGRHMDGYRVIVDKSTVPVGTGDKVRAAVAEELVVRGSTLAYSVVSNPEFLKEGA
AVEDFMRPDRIIVGADDERAVELMRQLYGPFQRNHEKLLVMDVRSAELTKYAANAMLATRISFMNELANLAETLGADIEL
VRQGIGSDPRIGWHFLYAGCGYGGSCFPKDVKALVRTGAEHGHDLLLLNAVEAVNDAQKLRLVDKVVSRFGENLAGRRFA
VWGLAFKPNTDDMREAPSRVVLGELLGRGASVCVYDPVAMDEARRIFGVDARLSYAERPMDALEAADALVIVTEWKEFRS
PDFERIRALLKQPVIFDGRNMYDPAVLRSEGIEYFGMGRR

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=446, Percent_Identity=35.2017937219731, Blast_Score=249, Evalue=5e-66,
Organism=Homo sapiens, GI296040438, Length=348, Percent_Identity=36.7816091954023, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI296040443, Length=293, Percent_Identity=37.8839590443686, Blast_Score=182, Evalue=6e-46,
Organism=Escherichia coli, GI1788340, Length=366, Percent_Identity=27.5956284153005, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI48994968, Length=450, Percent_Identity=28.2222222222222, Blast_Score=135, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17560350, Length=461, Percent_Identity=34.4902386117137, Blast_Score=238, Evalue=4e-63,
Organism=Drosophila melanogaster, GI17136908, Length=477, Percent_Identity=35.8490566037736, Blast_Score=251, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48148; Mature: 48148

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTVVGTGYVGLVSGACLADVGNDVLCLDVDPDKIRILEEGGIPIHEPGLLDVVRRNVA
CEEEEEECCHHHHHCCHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHH
AGRLSFTTDVERAARHGVIQFIAVGTPPDEDGSADLQYVLAAARNIGRHMDGYRVIVDKS
CCCEEEHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTGDKVRAAVAEELVVRGSTLAYSVVSNPEFLKEGAAVEDFMRPDRIIVGADDERA
CCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCHHHHCCCCEEEEECCCHHH
VELMRQLYGPFQRNHEKLLVMDVRSAELTKYAANAMLATRISFMNELANLAETLGADIEL
HHHHHHHHCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VRQGIGSDPRIGWHFLYAGCGYGGSCFPKDVKALVRTGAEHGHDLLLLNAVEAVNDAQKL
HHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHH
RLVDKVVSRFGENLAGRRFAVWGLAFKPNTDDMREAPSRVVLGELLGRGASVCVYDPVAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHCCCCCEEEECCCCH
DEARRIFGVDARLSYAERPMDALEAADALVIVTEWKEFRSPDFERIRALLKQPVIFDGRN
HHHHHHHCCCCHHHHHHCCHHHHHHCCEEEEEECHHHHCCCCHHHHHHHHHCCCEECCCC
MYDPAVLRSEGIEYFGMGRR
CCCCHHHHHCCCCEECCCCC
>Mature Secondary Structure
MKVTVVGTGYVGLVSGACLADVGNDVLCLDVDPDKIRILEEGGIPIHEPGLLDVVRRNVA
CEEEEEECCHHHHHCCHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHH
AGRLSFTTDVERAARHGVIQFIAVGTPPDEDGSADLQYVLAAARNIGRHMDGYRVIVDKS
CCCEEEHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTGDKVRAAVAEELVVRGSTLAYSVVSNPEFLKEGAAVEDFMRPDRIIVGADDERA
CCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCHHHHCCCCEEEEECCCHHH
VELMRQLYGPFQRNHEKLLVMDVRSAELTKYAANAMLATRISFMNELANLAETLGADIEL
HHHHHHHHCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VRQGIGSDPRIGWHFLYAGCGYGGSCFPKDVKALVRTGAEHGHDLLLLNAVEAVNDAQKL
HHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHH
RLVDKVVSRFGENLAGRRFAVWGLAFKPNTDDMREAPSRVVLGELLGRGASVCVYDPVAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHCCCCCEEEECCCCH
DEARRIFGVDARLSYAERPMDALEAADALVIVTEWKEFRSPDFERIRALLKQPVIFDGRN
HHHHHHHCCCCHHHHHHCCHHHHHHCCEEEEEECHHHHCCCCHHHHHHHHHCCCEECCCC
MYDPAVLRSEGIEYFGMGRR
CCCCHHHHHCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]