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The map label for this gene is tyrA [H]

Identifier: 119897361

GI number: 119897361

Start: 1152457

End: 1153347

Strand: Direct

Name: tyrA [H]

Synonym: azo1070

Alternate gene names: 119897361

Gene position: 1152457-1153347 (Clockwise)

Preceding gene: 119897360

Following gene: 119897362

Centisome position: 26.34

GC content: 70.03

Gene sequence:

>891_bases
ATGGCCTTGATCGGCAAGCTCGTCGTCTGCGGCGTCGGCCTCATCGGCGGATCTTTCGCGCTCGCGCTGAAGCAGGCCGG
CGCGGTGGAACGCGTCGTCGGTGTGGGCCGTAATCCGGCCACTCTCGCGCGCGCCGTGGAACTGGGCGTGATCGACGAAA
TCGCCGCGGGTTGGCGCGACGCGCTCGACGGCGCGGACTTCGTGTTGCTCGCCACGCCGGTCGGCCAGCTCGACGCAATC
ATGGAAGCCATGGCGCCCCACCTGCAGCCCGGCACCATCGTGACCGATGCAGGCAGCACCAAGCGCGACGTGATCGAAGC
GGTCTATCGCCGCCTCGACCCCCATCTCGCCACCGTCGTGCCCGCCCACCCGATCGCGGGCGCGGAAAAGAGCGGCGTGG
AAGCCGGCTTTCCGACGCTGTACCGGGGCAAGAAGGTGGTGGTGACGCCGCTGCCCGAGAACAGACCGGACGCGGTCGAG
CGCGTGCGCGCCGCCTGGACAGCCTGCGGCGCCACCGTGGTCGAGATGTCGCCGCAGGATCACGACCGCGTCTTCGCCGC
CGTCAGTCATCTGCCGCACCTTCTCGCGTTCGGTCTGGTGCACGACCTGGCGGGGCGCGCCAACGCCGAGTTGCTGTTCT
CCCACGCTGCCAGCGGCTTTCGCGACTTCACCCGCATCGCCGGCAGCCATCCGGAGATGTGGCGCGACATCTGCCTCGCC
AACCGGCAGGCCTTGCTGGCCGAACTCGACCAGTACCTGGCCGAACTTGCCTACCTGCGCGCGCTCTTGCTGGCGGGCGA
CGGCACCCGGCTGGAACAGCTGTTCGGCGAGGCGCGACGCGCGCGCGACGCATGGGCCGCGCAGTTCCCGCCCCCTTCTA
CCGCGGAATGA

Upstream 100 bases:

>100_bases
CATGCCGGAATGGCTGCGGGTCTCGATCGGGCTGCCCGAGGAGAACGCCCGCTTCATCACCGCGCTGCGCAACGCGCTGG
GCTGAGCGGCGGAGCGGTCC

Downstream 100 bases:

>100_bases
CCATGGAATTTCTCGATCTGCCGCCCATGCTCGCCGCGCGCGGGCAGGTGCGTTTGCCCGGCTCGAAGAGCATCTCGAAC
CGCAGCCTGCTGCTCGCCGC

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: Arogenate dehydrogenase; ADH; Cyclohexadienyl dehydrogenase; Prephenate dehydrogenase; PDH [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MALIGKLVVCGVGLIGGSFALALKQAGAVERVVGVGRNPATLARAVELGVIDEIAAGWRDALDGADFVLLATPVGQLDAI
MEAMAPHLQPGTIVTDAGSTKRDVIEAVYRRLDPHLATVVPAHPIAGAEKSGVEAGFPTLYRGKKVVVTPLPENRPDAVE
RVRAAWTACGATVVEMSPQDHDRVFAAVSHLPHLLAFGLVHDLAGRANAELLFSHAASGFRDFTRIAGSHPEMWRDICLA
NRQALLAELDQYLAELAYLRALLLAGDGTRLEQLFGEARRARDAWAAQFPPPSTAE

Sequences:

>Translated_296_residues
MALIGKLVVCGVGLIGGSFALALKQAGAVERVVGVGRNPATLARAVELGVIDEIAAGWRDALDGADFVLLATPVGQLDAI
MEAMAPHLQPGTIVTDAGSTKRDVIEAVYRRLDPHLATVVPAHPIAGAEKSGVEAGFPTLYRGKKVVVTPLPENRPDAVE
RVRAAWTACGATVVEMSPQDHDRVFAAVSHLPHLLAFGLVHDLAGRANAELLFSHAASGFRDFTRIAGSHPEMWRDICLA
NRQALLAELDQYLAELAYLRALLLAGDGTRLEQLFGEARRARDAWAAQFPPPSTAE
>Mature_295_residues
ALIGKLVVCGVGLIGGSFALALKQAGAVERVVGVGRNPATLARAVELGVIDEIAAGWRDALDGADFVLLATPVGQLDAIM
EAMAPHLQPGTIVTDAGSTKRDVIEAVYRRLDPHLATVVPAHPIAGAEKSGVEAGFPTLYRGKKVVVTPLPENRPDAVER
VRAAWTACGATVVEMSPQDHDRVFAAVSHLPHLLAFGLVHDLAGRANAELLFSHAASGFRDFTRIAGSHPEMWRDICLAN
RQALLAELDQYLAELAYLRALLLAGDGTRLEQLFGEARRARDAWAAQFPPPSTAE

Specific function: Is competent to function as either prephenate dehydrogenase or as arogenate dehydrogenase [H]

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF02153 PDH [H]

EC number: =1.3.1.43; =1.3.1.12 [H]

Molecular weight: Translated: 31481; Mature: 31349

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALIGKLVVCGVGLIGGSFALALKQAGAVERVVGVGRNPATLARAVELGVIDEIAAGWRD
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ALDGADFVLLATPVGQLDAIMEAMAPHLQPGTIVTDAGSTKRDVIEAVYRRLDPHLATVV
HCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHC
PAHPIAGAEKSGVEAGFPTLYRGKKVVVTPLPENRPDAVERVRAAWTACGATVVEMSPQD
CCCCCCCCCCCCCCCCCCHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCH
HDRVFAAVSHLPHLLAFGLVHDLAGRANAELLFSHAASGFRDFTRIAGSHPEMWRDICLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
NRQALLAELDQYLAELAYLRALLLAGDGTRLEQLFGEARRARDAWAAQFPPPSTAE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ALIGKLVVCGVGLIGGSFALALKQAGAVERVVGVGRNPATLARAVELGVIDEIAAGWRD
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ALDGADFVLLATPVGQLDAIMEAMAPHLQPGTIVTDAGSTKRDVIEAVYRRLDPHLATVV
HCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHC
PAHPIAGAEKSGVEAGFPTLYRGKKVVVTPLPENRPDAVERVRAAWTACGATVVEMSPQD
CCCCCCCCCCCCCCCCCCHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCH
HDRVFAAVSHLPHLLAFGLVHDLAGRANAELLFSHAASGFRDFTRIAGSHPEMWRDICLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
NRQALLAELDQYLAELAYLRALLLAGDGTRLEQLFGEARRARDAWAAQFPPPSTAE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7916685 [H]