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The map label for this gene is hisC1 [H]

Identifier: 119897360

GI number: 119897360

Start: 1151344

End: 1152441

Strand: Direct

Name: hisC1 [H]

Synonym: azo1069

Alternate gene names: 119897360

Gene position: 1151344-1152441 (Clockwise)

Preceding gene: 119897359

Following gene: 119897361

Centisome position: 26.31

GC content: 69.03

Gene sequence:

>1098_bases
ATGAGCGTAGCCAGCCGCGCGCCTGCCTACATCCGGTCCATCCAGCCCTACCAGCCGGGCAAGCCGATCTCCGAACTCGC
CCGCGAGATGGGCCTTCCCGAAGCCGACATCGTCAAGCTCGCCTCCAACGAGAATCCGCTCGGTATGGGCGCGAAGGCGC
GTGCCGCGGCCGAAGCGGCAATCCGCGAGGCCTTTCGCTATCCGGACGGCGGCGCCTTTGCGCTGAAGGCGGCGCTGGCA
CGCAAGTTCGGCGTGGATGCGGCGCAGCTCGTCATCGGCAACGGTTCCAACGACGTGCTCGAGATCGCCGCGCAGACCTT
CCTTGCGCCCGGTACTTCGGCCGTGTTCTCGCAGTACTCCTTCGCGGTCTATCCGCTCGCCACCAATGCCCGCGGCGCGC
GCTGCATCCAGGTGCCGGCACAGGCCTACGGGCACGACCTCGACGCGATGGCCGCGGCGATCGCGCCCGACACGCGCATC
GTGTTCATCGCCAATCCGAACAATCCCACCGGCACCTTCGTTGGCGGTGCCGCACTCGAGGCCTTCCTCGCCAAGGTGCC
CGAAGACGTGCTGGTGGTGCTGGACGAGGCCTACACCGAGTTCCTCGAACCCGAGCAGCGCTACGACTCGCTGGCCTGGC
TTGCCCGGTTCCCCAACCTCCTCGTGTCGCGCACGCTGTGCAAGGCCTACGGCTTGGCCGGGCTGCGGGTGGGGTATGCC
ATCGCCCACCCCGACGTGGCCGATCTGATGAACCGCGTGCGCCAGCCGTTCAACGTGTCCGCGGTGGCGCTGGCGGCGGC
CGAGGCCGCGCTGGGCGACGACGATTTCGTCGCCCGTACCGCCGACATCAACCGCCGTGGCAAGCAGCAGCTCACTGACG
CGTTCGCCAGCCTGGGGCTGGAGTGGATTCCGTCCGCCGGCAACTTCGTCACCGTGCGCGTGGGCGACGCCGCGGCGGTC
AACCTCGCGCTGCTGCGCCAGGGTGTGATCGTGCGTCCGATCGCCGGCTATGGCATGCCGGAATGGCTGCGGGTCTCGAT
CGGGCTGCCCGAGGAGAACGCCCGCTTCATCACCGCGCTGCGCAACGCGCTGGGCTGA

Upstream 100 bases:

>100_bases
CGGTGGCCGCCGCGCTGCGCGAGCTGAACGAGCGCGCCGCCTTCGTCAAGGTGCTGGGCTCCTACCCGGTCGCCGCGATC
TGAACTTTCAGGAGTCTGCC

Downstream 100 bases:

>100_bases
GCGGCGGAGCGGTCCATGGCCTTGATCGGCAAGCTCGTCGTCTGCGGCGTCGGCCTCATCGGCGGATCTTTCGCGCTCGC
GCTGAAGCAGGCCGGCGCGG

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 2 [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSVASRAPAYIRSIQPYQPGKPISELAREMGLPEADIVKLASNENPLGMGAKARAAAEAAIREAFRYPDGGAFALKAALA
RKFGVDAAQLVIGNGSNDVLEIAAQTFLAPGTSAVFSQYSFAVYPLATNARGARCIQVPAQAYGHDLDAMAAAIAPDTRI
VFIANPNNPTGTFVGGAALEAFLAKVPEDVLVVLDEAYTEFLEPEQRYDSLAWLARFPNLLVSRTLCKAYGLAGLRVGYA
IAHPDVADLMNRVRQPFNVSAVALAAAEAALGDDDFVARTADINRRGKQQLTDAFASLGLEWIPSAGNFVTVRVGDAAAV
NLALLRQGVIVRPIAGYGMPEWLRVSIGLPEENARFITALRNALG

Sequences:

>Translated_365_residues
MSVASRAPAYIRSIQPYQPGKPISELAREMGLPEADIVKLASNENPLGMGAKARAAAEAAIREAFRYPDGGAFALKAALA
RKFGVDAAQLVIGNGSNDVLEIAAQTFLAPGTSAVFSQYSFAVYPLATNARGARCIQVPAQAYGHDLDAMAAAIAPDTRI
VFIANPNNPTGTFVGGAALEAFLAKVPEDVLVVLDEAYTEFLEPEQRYDSLAWLARFPNLLVSRTLCKAYGLAGLRVGYA
IAHPDVADLMNRVRQPFNVSAVALAAAEAALGDDDFVARTADINRRGKQQLTDAFASLGLEWIPSAGNFVTVRVGDAAAV
NLALLRQGVIVRPIAGYGMPEWLRVSIGLPEENARFITALRNALG
>Mature_364_residues
SVASRAPAYIRSIQPYQPGKPISELAREMGLPEADIVKLASNENPLGMGAKARAAAEAAIREAFRYPDGGAFALKAALAR
KFGVDAAQLVIGNGSNDVLEIAAQTFLAPGTSAVFSQYSFAVYPLATNARGARCIQVPAQAYGHDLDAMAAAIAPDTRIV
FIANPNNPTGTFVGGAALEAFLAKVPEDVLVVLDEAYTEFLEPEQRYDSLAWLARFPNLLVSRTLCKAYGLAGLRVGYAI
AHPDVADLMNRVRQPFNVSAVALAAAEAALGDDDFVARTADINRRGKQQLTDAFASLGLEWIPSAGNFVTVRVGDAAAVN
LALLRQGVIVRPIAGYGMPEWLRVSIGLPEENARFITALRNALG

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=375, Percent_Identity=29.0666666666667, Blast_Score=125, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6322075, Length=360, Percent_Identity=25.5555555555556, Blast_Score=105, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 38728; Mature: 38596

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVASRAPAYIRSIQPYQPGKPISELAREMGLPEADIVKLASNENPLGMGAKARAAAEAA
CCCCCCCCHHHHCCCCCCCCCCHHHHHHHHCCCHHHHEEECCCCCCCCCCCHHHHHHHHH
IREAFRYPDGGAFALKAALARKFGVDAAQLVIGNGSNDVLEIAAQTFLAPGTSAVFSQYS
HHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHCCC
FAVYPLATNARGARCIQVPAQAYGHDLDAMAAAIAPDTRIVFIANPNNPTGTFVGGAALE
EEEEEEECCCCCCEEEECCHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCCCEECHHHHH
AFLAKVPEDVLVVLDEAYTEFLEPEQRYDSLAWLARFPNLLVSRTLCKAYGLAGLRVGYA
HHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEE
IAHPDVADLMNRVRQPFNVSAVALAAAEAALGDDDFVARTADINRRGKQQLTDAFASLGL
ECCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHEEEHHCCCHHHHHHHHHHHHHCCC
EWIPSAGNFVTVRVGDAAAVNLALLRQGVIVRPIAGYGMPEWLRVSIGLPEENARFITAL
EECCCCCCEEEEEECCHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCCCCHHHHHHH
RNALG
HHHCC
>Mature Secondary Structure 
SVASRAPAYIRSIQPYQPGKPISELAREMGLPEADIVKLASNENPLGMGAKARAAAEAA
CCCCCCCHHHHCCCCCCCCCCHHHHHHHHCCCHHHHEEECCCCCCCCCCCHHHHHHHHH
IREAFRYPDGGAFALKAALARKFGVDAAQLVIGNGSNDVLEIAAQTFLAPGTSAVFSQYS
HHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHCCC
FAVYPLATNARGARCIQVPAQAYGHDLDAMAAAIAPDTRIVFIANPNNPTGTFVGGAALE
EEEEEEECCCCCCEEEECCHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCCCEECHHHHH
AFLAKVPEDVLVVLDEAYTEFLEPEQRYDSLAWLARFPNLLVSRTLCKAYGLAGLRVGYA
HHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEE
IAHPDVADLMNRVRQPFNVSAVALAAAEAALGDDDFVARTADINRRGKQQLTDAFASLGL
ECCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHEEEHHCCCHHHHHHHHHHHHHCCC
EWIPSAGNFVTVRVGDAAAVNLALLRQGVIVRPIAGYGMPEWLRVSIGLPEENARFITAL
EECCCCCCEEEEEECCHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCCCCHHHHHHH
RNALG
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]