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The map label for this gene is serC [H]

Identifier: 119897358

GI number: 119897358

Start: 1149150

End: 1150247

Strand: Direct

Name: serC [H]

Synonym: azo1067

Alternate gene names: 119897358

Gene position: 1149150-1150247 (Clockwise)

Preceding gene: 119897357

Following gene: 119897359

Centisome position: 26.26

GC content: 66.48

Gene sequence:

>1098_bases
ATGACACGCGTCTGGAATTTCGCGGCCGGTCCGGCCGCGCTGCCCGCCGAGGTGCTGCAGCAGGCCGCCGAGGAGATGCT
CGACTGGCGCGGTGCCGGCGTCGGCGTCATGGAAATGAGCCACCGCAGCAAGGAGTTCGTGTCGATCGCCGAGCAGGCCG
AGGCCGACCTGCGCGAACTGATGGCGATTCCGGCCAACTACCGCGTGCTGTTCATGCAGGGCGGGGCGATCGCCGAGAAC
GCGATCATCCCGATGAACCTGATGGGCGAGGAGAAGCGTGCGGACTACGTGGTCACCGGCTCGTGGTCGGTGAAGTCGCA
GAAGGAGGCGCGCAAGTACGGCGAGGTCAATATCGCCGCGACCTCGGAGGCGAGCGGCTACACCACGGTGCCGCCGATGA
GCGAGTGGAAGCTGTCGGCGCGCCCGTCCTACCTCTTCACCTGCACCAACGAGACCATCGGCGGCGTCGAGTATCCGTTC
GAGCCCGATCTGGCCCGGATCGGCCGCGCCGAGGTGCCGGTGGTGGCCGACGTGTCCTCGCACATCCTGTCGCGCCCGTT
CGATGTGACCAAGTACGGCCTGCTGTTCGGCGGCGCGCAGAAGAACATCGGTCCTGCCGGGCTCACGATCGTCATCGTCC
GCGACGACCTGCTCGGGCGCGCCGCGCCGTTCTGCCCCACGGCCTTCGACTACCGCACCGTGGCCGACAACGGCTCGATG
TACAACACCCCACCCACCTATGCCATCTACATCGCCGGCCTCGTGTTCCAGTGGCTCAAGCGCAAGGGCGGCGTCGCCGG
CATCGAAGCGCAGAACATCGCCAAGGCGGAACTGTTGTACGGCTTCCTCGACGACTGTCCGTTCTACGAGAACCGCATCG
ATCCGGCCTGCCGCTCGCGCATGAACGTGCCCTTCTTCCTCAAGGACGAATCGCTCAACGACCGCTTCCTGGCGGGCGCC
AAGGATGCCGGCCTGGTGCAGCTGAAGGGCCACAAGTCGGTGGGCGGCATGCGCGCCTCGATCTACAACGCGATGCCGCT
CGAAGGCGTGCAGGCGCTGGTCGATTACATGCGCGACTTCGCGCTTCGCCACGGATAA

Upstream 100 bases:

>100_bases
CCGGCGCCGAGGCGGACGAACTGGTGGAAGGTGGCGAAGAGGGCGCCGCGGACGGCGAGGATGCCGGCGCGCCGGGCGCC
GCGGGTGAAGGAGAACAGGA

Downstream 100 bases:

>100_bases
GCGGAGCCGGTACCATGAGCGACGAACTCCTGAACCTGCGTAACCAGATCGACCGTCTGGACGAGGAAATCCTTGCCCGC
CTTGCCGAGCGCGCGCGTTG

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTRVWNFAAGPAALPAEVLQQAAEEMLDWRGAGVGVMEMSHRSKEFVSIAEQAEADLRELMAIPANYRVLFMQGGAIAEN
AIIPMNLMGEEKRADYVVTGSWSVKSQKEARKYGEVNIAATSEASGYTTVPPMSEWKLSARPSYLFTCTNETIGGVEYPF
EPDLARIGRAEVPVVADVSSHILSRPFDVTKYGLLFGGAQKNIGPAGLTIVIVRDDLLGRAAPFCPTAFDYRTVADNGSM
YNTPPTYAIYIAGLVFQWLKRKGGVAGIEAQNIAKAELLYGFLDDCPFYENRIDPACRSRMNVPFFLKDESLNDRFLAGA
KDAGLVQLKGHKSVGGMRASIYNAMPLEGVQALVDYMRDFALRHG

Sequences:

>Translated_365_residues
MTRVWNFAAGPAALPAEVLQQAAEEMLDWRGAGVGVMEMSHRSKEFVSIAEQAEADLRELMAIPANYRVLFMQGGAIAEN
AIIPMNLMGEEKRADYVVTGSWSVKSQKEARKYGEVNIAATSEASGYTTVPPMSEWKLSARPSYLFTCTNETIGGVEYPF
EPDLARIGRAEVPVVADVSSHILSRPFDVTKYGLLFGGAQKNIGPAGLTIVIVRDDLLGRAAPFCPTAFDYRTVADNGSM
YNTPPTYAIYIAGLVFQWLKRKGGVAGIEAQNIAKAELLYGFLDDCPFYENRIDPACRSRMNVPFFLKDESLNDRFLAGA
KDAGLVQLKGHKSVGGMRASIYNAMPLEGVQALVDYMRDFALRHG
>Mature_364_residues
TRVWNFAAGPAALPAEVLQQAAEEMLDWRGAGVGVMEMSHRSKEFVSIAEQAEADLRELMAIPANYRVLFMQGGAIAENA
IIPMNLMGEEKRADYVVTGSWSVKSQKEARKYGEVNIAATSEASGYTTVPPMSEWKLSARPSYLFTCTNETIGGVEYPFE
PDLARIGRAEVPVVADVSSHILSRPFDVTKYGLLFGGAQKNIGPAGLTIVIVRDDLLGRAAPFCPTAFDYRTVADNGSMY
NTPPTYAIYIAGLVFQWLKRKGGVAGIEAQNIAKAELLYGFLDDCPFYENRIDPACRSRMNVPFFLKDESLNDRFLAGAK
DAGLVQLKGHKSVGGMRASIYNAMPLEGVQALVDYMRDFALRHG

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=369, Percent_Identity=45.7994579945799, Blast_Score=349, Evalue=3e-96,
Organism=Homo sapiens, GI10863955, Length=364, Percent_Identity=41.2087912087912, Blast_Score=297, Evalue=9e-81,
Organism=Escherichia coli, GI1787136, Length=366, Percent_Identity=54.6448087431694, Blast_Score=413, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17506897, Length=369, Percent_Identity=45.7994579945799, Blast_Score=333, Evalue=9e-92,
Organism=Saccharomyces cerevisiae, GI6324758, Length=386, Percent_Identity=41.7098445595855, Blast_Score=291, Evalue=1e-79,
Organism=Drosophila melanogaster, GI21356589, Length=362, Percent_Identity=48.8950276243094, Blast_Score=366, Evalue=1e-101,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39989; Mature: 39858

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVWNFAAGPAALPAEVLQQAAEEMLDWRGAGVGVMEMSHRSKEFVSIAEQAEADLREL
CCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
MAIPANYRVLFMQGGAIAENAIIPMNLMGEEKRADYVVTGSWSVKSQKEARKYGEVNIAA
HHCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHCCEEEEE
TSEASGYTTVPPMSEWKLSARPSYLFTCTNETIGGVEYPFEPDLARIGRAEVPVVADVSS
ECCCCCCCCCCCCHHCEECCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCEEECHHH
HILSRPFDVTKYGLLFGGAQKNIGPAGLTIVIVRDDLLGRAAPFCPTAFDYRTVADNGSM
HHHCCCCCHHHHHEEECCCCCCCCCCCEEEEEEECCHHCCCCCCCCCCCCCEEECCCCCC
YNTPPTYAIYIAGLVFQWLKRKGGVAGIEAQNIAKAELLYGFLDDCPFYENRIDPACRSR
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHC
MNVPFFLKDESLNDRFLAGAKDAGLVQLKGHKSVGGMRASIYNAMPLEGVQALVDYMRDF
CCCCEEEECCCCCCCEECCCCCCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHH
ALRHG
HHCCC
>Mature Secondary Structure 
TRVWNFAAGPAALPAEVLQQAAEEMLDWRGAGVGVMEMSHRSKEFVSIAEQAEADLREL
CEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
MAIPANYRVLFMQGGAIAENAIIPMNLMGEEKRADYVVTGSWSVKSQKEARKYGEVNIAA
HHCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHCCEEEEE
TSEASGYTTVPPMSEWKLSARPSYLFTCTNETIGGVEYPFEPDLARIGRAEVPVVADVSS
ECCCCCCCCCCCCHHCEECCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCEEECHHH
HILSRPFDVTKYGLLFGGAQKNIGPAGLTIVIVRDDLLGRAAPFCPTAFDYRTVADNGSM
HHHCCCCCHHHHHEEECCCCCCCCCCCEEEEEEECCHHCCCCCCCCCCCCCEEECCCCCC
YNTPPTYAIYIAGLVFQWLKRKGGVAGIEAQNIAKAELLYGFLDDCPFYENRIDPACRSR
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHC
MNVPFFLKDESLNDRFLAGAKDAGLVQLKGHKSVGGMRASIYNAMPLEGVQALVDYMRDF
CCCCEEEECCCCCCCEECCCCCCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHH
ALRHG
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA