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The map label for this gene is pheA [H]

Identifier: 119897359

GI number: 119897359

Start: 1150262

End: 1151326

Strand: Direct

Name: pheA [H]

Synonym: azo1068

Alternate gene names: 119897359

Gene position: 1150262-1151326 (Clockwise)

Preceding gene: 119897358

Following gene: 119897360

Centisome position: 26.29

GC content: 67.89

Gene sequence:

>1065_bases
ATGAGCGACGAACTCCTGAACCTGCGTAACCAGATCGACCGTCTGGACGAGGAAATCCTTGCCCGCCTTGCCGAGCGCGC
GCGTTGTGCGCAGCGCGTGGGCGAGATCAAGCACGGCAACATCTACCGGCCGGAACGCGAGGCCCAGGTGCTGCGCCGGC
TGGCGGACCTCAACGGCGGACCGCTGCCCGACGTCGCGGTGCAGAAGATCTTCCGCGAAATCATGTCGGCCTGCCTGGGT
CTTGAGCAGCCGCTGAAGGTGGCTTATCTCGGCCCCGCCGGCACCTTCTCGGAAAGTGCCAGCCGCAAGCATTTCGGCGC
GGCCCCCAACGTCCTGCCGACGCCGTCGATCGACGAGGTGTTCCGCGCGGTCGAGTCGGGCAATGCGGACTATGGCGTGG
TGCCGGTGGAGAACTCCACCGAGGGCGCGGTCGGCGGCACGCTGGATTTGCTGCTGGCCAATCCGCTGAAGGTGTGCGGC
GAGGTCAAGCTGCGCATCCACCAGAACCTGCTGTCGCGCGCCGAGGGCATCGGCGGCGCGAAGCGCCTGTATTCGCACGC
GCAGTCGCTGGCGCAGTGCCACGAGTGGCTCAACCGCAACCTGGCCCATCTGCCGCGCATCCCGGTGGCGAGCAACGCCG
AGGCGGCGCGGCTGGCGGCGGAAGATCCCGAATCGTGCGCAATCGCCGGCGAGGCCGCGGCCGAGCTGTACGGCCTCAAC
AAGCTCGCCACCAACATCGAGGACGACCCCAACAACACGACGCGTTTCCTCGTCATTGCCAGCCATGATGCAGGGCCGTC
CGGCAACGACAAGACGTCGCTGGTGTGTTCTGCGCAGAACCGCCCCGGGGCGATGCATGCGCTGCTCGAACCGCTGGCGC
GCCACGGCGTCGACATGAGCAAGCTCGAGTCGCGCCCGGCGCGCAGTGGCTTGTGGGAATACGTGTTCTACGTCGACATC
CAGGGGCATCAGACCGATGCCGCGGTGGCCGCCGCGCTGCGCGAGCTGAACGAGCGCGCCGCCTTCGTCAAGGTGCTGGG
CTCCTACCCGGTCGCCGCGATCTGA

Upstream 100 bases:

>100_bases
GCGCCTCGATCTACAACGCGATGCCGCTCGAAGGCGTGCAGGCGCTGGTCGATTACATGCGCGACTTCGCGCTTCGCCAC
GGATAAGCGGAGCCGGTACC

Downstream 100 bases:

>100_bases
ACTTTCAGGAGTCTGCCATGAGCGTAGCCAGCCGCGCGCCTGCCTACATCCGGTCCATCCAGCCCTACCAGCCGGGCAAG
CCGATCTCCGAACTCGCCCG

Product: chorismate mutase/prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSDELLNLRNQIDRLDEEILARLAERARCAQRVGEIKHGNIYRPEREAQVLRRLADLNGGPLPDVAVQKIFREIMSACLG
LEQPLKVAYLGPAGTFSESASRKHFGAAPNVLPTPSIDEVFRAVESGNADYGVVPVENSTEGAVGGTLDLLLANPLKVCG
EVKLRIHQNLLSRAEGIGGAKRLYSHAQSLAQCHEWLNRNLAHLPRIPVASNAEAARLAAEDPESCAIAGEAAAELYGLN
KLATNIEDDPNNTTRFLVIASHDAGPSGNDKTSLVCSAQNRPGAMHALLEPLARHGVDMSKLESRPARSGLWEYVFYVDI
QGHQTDAAVAAALRELNERAAFVKVLGSYPVAAI

Sequences:

>Translated_354_residues
MSDELLNLRNQIDRLDEEILARLAERARCAQRVGEIKHGNIYRPEREAQVLRRLADLNGGPLPDVAVQKIFREIMSACLG
LEQPLKVAYLGPAGTFSESASRKHFGAAPNVLPTPSIDEVFRAVESGNADYGVVPVENSTEGAVGGTLDLLLANPLKVCG
EVKLRIHQNLLSRAEGIGGAKRLYSHAQSLAQCHEWLNRNLAHLPRIPVASNAEAARLAAEDPESCAIAGEAAAELYGLN
KLATNIEDDPNNTTRFLVIASHDAGPSGNDKTSLVCSAQNRPGAMHALLEPLARHGVDMSKLESRPARSGLWEYVFYVDI
QGHQTDAAVAAALRELNERAAFVKVLGSYPVAAI
>Mature_353_residues
SDELLNLRNQIDRLDEEILARLAERARCAQRVGEIKHGNIYRPEREAQVLRRLADLNGGPLPDVAVQKIFREIMSACLGL
EQPLKVAYLGPAGTFSESASRKHFGAAPNVLPTPSIDEVFRAVESGNADYGVVPVENSTEGAVGGTLDLLLANPLKVCGE
VKLRIHQNLLSRAEGIGGAKRLYSHAQSLAQCHEWLNRNLAHLPRIPVASNAEAARLAAEDPESCAIAGEAAAELYGLNK
LATNIEDDPNNTTRFLVIASHDAGPSGNDKTSLVCSAQNRPGAMHALLEPLARHGVDMSKLESRPARSGLWEYVFYVDIQ
GHQTDAAVAAALRELNERAAFVKVLGSYPVAAI

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=377, Percent_Identity=33.9522546419098, Blast_Score=176, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6324013, Length=323, Percent_Identity=26.9349845201238, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 38197; Mature: 38066

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDELLNLRNQIDRLDEEILARLAERARCAQRVGEIKHGNIYRPEREAQVLRRLADLNGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCC
PLPDVAVQKIFREIMSACLGLEQPLKVAYLGPAGTFSESASRKHFGAAPNVLPTPSIDEV
CCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHCCCCCCCCCCCCCCCCHHHH
FRAVESGNADYGVVPVENSTEGAVGGTLDLLLANPLKVCGEVKLRIHQNLLSRAEGIGGA
HHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHH
KRLYSHAQSLAQCHEWLNRNLAHLPRIPVASNAEAARLAAEDPESCAIAGEAAAELYGLN
HHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHCCCCCCHHEEHHHHHHHHHHHH
KLATNIEDDPNNTTRFLVIASHDAGPSGNDKTSLVCSAQNRPGAMHALLEPLARHGVDMS
HHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHH
KLESRPARSGLWEYVFYVDIQGHQTDAAVAAALRELNERAAFVKVLGSYPVAAI
HHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SDELLNLRNQIDRLDEEILARLAERARCAQRVGEIKHGNIYRPEREAQVLRRLADLNGG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCC
PLPDVAVQKIFREIMSACLGLEQPLKVAYLGPAGTFSESASRKHFGAAPNVLPTPSIDEV
CCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHCCCCCCCCCCCCCCCCHHHH
FRAVESGNADYGVVPVENSTEGAVGGTLDLLLANPLKVCGEVKLRIHQNLLSRAEGIGGA
HHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHH
KRLYSHAQSLAQCHEWLNRNLAHLPRIPVASNAEAARLAAEDPESCAIAGEAAAELYGLN
HHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHCCCCCCHHEEHHHHHHHHHHHH
KLATNIEDDPNNTTRFLVIASHDAGPSGNDKTSLVCSAQNRPGAMHALLEPLARHGVDMS
HHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHH
KLESRPARSGLWEYVFYVDIQGHQTDAAVAAALRELNERAAFVKVLGSYPVAAI
HHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10094619 [H]