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The map label for this gene is vsrD1 [H]

Identifier: 119896860

GI number: 119896860

Start: 599710

End: 600345

Strand: Reverse

Name: vsrD1 [H]

Synonym: azo0569

Alternate gene names: 119896860

Gene position: 600345-599710 (Counterclockwise)

Preceding gene: 119896861

Following gene: 119896858

Centisome position: 13.72

GC content: 67.61

Gene sequence:

>636_bases
ATGCTGCATCTCGCCATCGTCGATGACCACGCGATCGTGCGCGCAGGCTTTCGCGAAATGCTTGCGACCGAAACCGACCT
CCACATCGTGTTCGAGGCCGCCACCGGCGAGGATGCGCTCGCGCGCGTCGCCGACACCGGCTGCGATCTGCTGCTGCTGG
ACCTCTCGCTGCCCGGCCAAAGCGGTGTCGATGTGCTGCGCACCTTGCGCCGCCGCGGCGATTCGACGCGGGTGCTGGTA
CTCACCGGCTTTCCGGAGGACCGCTATGCGGTGGCGATGATCCGGCTCGGCGCCGACGGCTATCTATGCAAGAACTGCGA
GCGCGACGAGCTGGTGCAGGCGATCCGCACGATCGCACAGGGCCGGCGCTATCTCAGCGCGCGCACCGCCGAACTGCTGG
CGGGTGAAATCGCCGGCGATGGCAGCGGCGCCGCGCACGAGCAGTTGTCGGAGCGCGAGCTGCAGGTCTTCCTGCGCCTC
GCGCACGGCGAGTCGGTATCGGCAATCGCGGACGCCCTGCATCTCAGCATCAAGACCGTCAGCACCTACCGCAGCCGGGT
GCTGGAAAAGCTGGACGTCACCAGCAACGCCGAACTCGCCACCTACGCCATCCGCCACGGCCTGATCGTGGCCTGA

Upstream 100 bases:

>100_bases
GGTCCTTTCTGCAACGCCAGCTGCGGACGGCGGCGCGCAGCACGCCCGCCCCACGGACACGGGCACGCCCCGCCGTACTG
GCCCGCCCCCGGAGCTAGCC

Downstream 100 bases:

>100_bases
TCCGCTCACGCCGCCAGCGCCAATTCCGCGCCGCGCGCCGCATCCAGCGGCAACGCCGCGGCGATGCGGGTGCCGGCGCC
GGCCCGGCTATCCACACTGA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: Global activator [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MLHLAIVDDHAIVRAGFREMLATETDLHIVFEAATGEDALARVADTGCDLLLLDLSLPGQSGVDVLRTLRRRGDSTRVLV
LTGFPEDRYAVAMIRLGADGYLCKNCERDELVQAIRTIAQGRRYLSARTAELLAGEIAGDGSGAAHEQLSERELQVFLRL
AHGESVSAIADALHLSIKTVSTYRSRVLEKLDVTSNAELATYAIRHGLIVA

Sequences:

>Translated_211_residues
MLHLAIVDDHAIVRAGFREMLATETDLHIVFEAATGEDALARVADTGCDLLLLDLSLPGQSGVDVLRTLRRRGDSTRVLV
LTGFPEDRYAVAMIRLGADGYLCKNCERDELVQAIRTIAQGRRYLSARTAELLAGEIAGDGSGAAHEQLSERELQVFLRL
AHGESVSAIADALHLSIKTVSTYRSRVLEKLDVTSNAELATYAIRHGLIVA
>Mature_211_residues
MLHLAIVDDHAIVRAGFREMLATETDLHIVFEAATGEDALARVADTGCDLLLLDLSLPGQSGVDVLRTLRRRGDSTRVLV
LTGFPEDRYAVAMIRLGADGYLCKNCERDELVQAIRTIAQGRRYLSARTAELLAGEIAGDGSGAAHEQLSERELQVFLRL
AHGESVSAIADALHLSIKTVSTYRSRVLEKLDVTSNAELATYAIRHGLIVA

Specific function: Positively controls the production of the autoinducer N- butyryl-homoserine lactone and the formation of the virulence factors pyocyanine, cyanide, and lipase [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=36.8421052631579, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1790102, Length=200, Percent_Identity=37.5, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1788521, Length=194, Percent_Identity=35.5670103092784, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1788712, Length=207, Percent_Identity=29.4685990338164, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1786747, Length=204, Percent_Identity=29.4117647058824, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787473, Length=180, Percent_Identity=30, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788546, Length=204, Percent_Identity=26.9607843137255, Blast_Score=77, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22921; Mature: 22921

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHLAIVDDHAIVRAGFREMLATETDLHIVFEAATGEDALARVADTGCDLLLLDLSLPGQ
CEEEEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCCCCEEEEEECCCCC
SGVDVLRTLRRRGDSTRVLVLTGFPEDRYAVAMIRLGADGYLCKNCERDELVQAIRTIAQ
CCHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
GRRYLSARTAELLAGEIAGDGSGAAHEQLSERELQVFLRLAHGESVSAIADALHLSIKTV
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
STYRSRVLEKLDVTSNAELATYAIRHGLIVA
HHHHHHHHHHHCCCCCCHHHHHHHHCCCEEC
>Mature Secondary Structure
MLHLAIVDDHAIVRAGFREMLATETDLHIVFEAATGEDALARVADTGCDLLLLDLSLPGQ
CEEEEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCCCCEEEEEECCCCC
SGVDVLRTLRRRGDSTRVLVLTGFPEDRYAVAMIRLGADGYLCKNCERDELVQAIRTIAQ
CCHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
GRRYLSARTAELLAGEIAGDGSGAAHEQLSERELQVFLRLAHGESVSAIADALHLSIKTV
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
STYRSRVLEKLDVTSNAELATYAIRHGLIVA
HHHHHHHHHHHCCCCCCHHHHHHHHCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9159518; 10984043 [H]