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The map label for this gene is mlaC [H]

Identifier: 119896858

GI number: 119896858

Start: 597475

End: 598143

Strand: Reverse

Name: mlaC [H]

Synonym: azo0567

Alternate gene names: 119896858

Gene position: 598143-597475 (Counterclockwise)

Preceding gene: 119896860

Following gene: 119896855

Centisome position: 13.67

GC content: 70.55

Gene sequence:

>669_bases
ATGACCATCCGCCACCCGCCCGTGCATGCGGGCGCTCCGCCTGCGTCGGTGCCGCGCTGGCTGCGGCAGCTGGCGTGGCT
GCTGGTATTCGCCACCGCCGCGGCGCACGGGCAAGGCGCCGCGCCGGACGAGTTGGTGCGCGGGGTTACCGACGAAGTGC
TGACCGTGCTGCGGCAGGACAAGGACCTCAAGGCCGGCGACCGGGCGCGTGCGATCCGCCTGATCGATGAAAAGATTGCA
CCGCATTTCGACTTTGCCCGCATGACCGCCTTGGCGGTCGGCCCGCCTTGGCGCCAGGCCTCGCCACCCGAACGCGAAGC
GCTGACGCGGGAGTTCCGTACGCTGCTGGTGCGCACCTACGCCAACGCGCTGACGGCCTACCGCGACCAGACAGTGCACT
TTCCACCCTCGCCCCAAGCACAGGGCGACGACGTGGTGATCCGCAGCCAGATCCGCCAGTCCGGCGCGGCGCCGATCGGG
CTCGATTACCGGCTGCGCCGCGGCGCGGATGGCTGGAAGGTTTTCGACGTGGCGGTCGATAGCGTCAGCCTGGTGACGAG
CTACCGCGGCAGCTTTGCGGCCGAGCTGGCGAAGGGCGGGCCGCAGGCGCTGATCGACACGCTGCGCGAACAGAACCGTC
GCTACGAGCCCGAGCGGCCGCCGAGCTGA

Upstream 100 bases:

>100_bases
GCGCCGCCTAAGATGGAACGGAAACGCCGGGCAGGCCCCGCGGCTCTGCGAGCAAGCGGGAGGCCCGGGCTGCGGTCGTC
CCATCCACCGGAGGCTCACC

Downstream 100 bases:

>100_bases
CGCCGAACGCGGGCAGCCCCCGCCTTCACGACAACGACCCACCGAGGAGAACCGCGATGATGAAAGCCCGTATCCTGCTG
TTGAGCACGCTGGCGGCGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTIRHPPVHAGAPPASVPRWLRQLAWLLVFATAAAHGQGAAPDELVRGVTDEVLTVLRQDKDLKAGDRARAIRLIDEKIA
PHFDFARMTALAVGPPWRQASPPEREALTREFRTLLVRTYANALTAYRDQTVHFPPSPQAQGDDVVIRSQIRQSGAAPIG
LDYRLRRGADGWKVFDVAVDSVSLVTSYRGSFAAELAKGGPQALIDTLREQNRRYEPERPPS

Sequences:

>Translated_222_residues
MTIRHPPVHAGAPPASVPRWLRQLAWLLVFATAAAHGQGAAPDELVRGVTDEVLTVLRQDKDLKAGDRARAIRLIDEKIA
PHFDFARMTALAVGPPWRQASPPEREALTREFRTLLVRTYANALTAYRDQTVHFPPSPQAQGDDVVIRSQIRQSGAAPIG
LDYRLRRGADGWKVFDVAVDSVSLVTSYRGSFAAELAKGGPQALIDTLREQNRRYEPERPPS
>Mature_221_residues
TIRHPPVHAGAPPASVPRWLRQLAWLLVFATAAAHGQGAAPDELVRGVTDEVLTVLRQDKDLKAGDRARAIRLIDEKIAP
HFDFARMTALAVGPPWRQASPPEREALTREFRTLLVRTYANALTAYRDQTVHFPPSPQAQGDDVVIRSQIRQSGAAPIGL
DYRLRRGADGWKVFDVAVDSVSLVTSYRGSFAAELAKGGPQALIDTLREQNRRYEPERPPS

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=192, Percent_Identity=26.5625, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 24543; Mature: 24412

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRHPPVHAGAPPASVPRWLRQLAWLLVFATAAAHGQGAAPDELVRGVTDEVLTVLRQD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
KDLKAGDRARAIRLIDEKIAPHFDFARMTALAVGPPWRQASPPEREALTREFRTLLVRTY
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ANALTAYRDQTVHFPPSPQAQGDDVVIRSQIRQSGAAPIGLDYRLRRGADGWKVFDVAVD
HHHHHHHHCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCCEEHHHHHH
SVSLVTSYRGSFAAELAKGGPQALIDTLREQNRRYEPERPPS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TIRHPPVHAGAPPASVPRWLRQLAWLLVFATAAAHGQGAAPDELVRGVTDEVLTVLRQD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
KDLKAGDRARAIRLIDEKIAPHFDFARMTALAVGPPWRQASPPEREALTREFRTLLVRTY
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ANALTAYRDQTVHFPPSPQAQGDDVVIRSQIRQSGAAPIGLDYRLRRGADGWKVFDVAVD
HHHHHHHHCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCCEEHHHHHH
SVSLVTSYRGSFAAELAKGGPQALIDTLREQNRRYEPERPPS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]