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The map label for this gene is moaB [H]

Identifier: 119776657

GI number: 119776657

Start: 4160346

End: 4160882

Strand: Direct

Name: moaB [H]

Synonym: Sama_3525

Alternate gene names: 119776657

Gene position: 4160346-4160882 (Clockwise)

Preceding gene: 119776656

Following gene: 119776658

Centisome position: 96.61

GC content: 58.1

Gene sequence:

>537_bases
ATGGGACACTGCCGCGAAACCGAATTCAAACCCCTGAATATTGCTGTGCTGACACTGTCAGACACCCGGGATGAGTCCAA
CGATACTTCGGGCGCCTTCCTTGCCGATGCCGTTACCGAAGTGGGACACAAGCTCGTTGCCCGGCGCATTATCAAGGATG
ACAAATATCTCATCCGCGCCCAAATCTCCGCCTGGATAGCCGACCCTGAGGTGCAGGTCATTATCAGCACCGGCGGTACT
GGCTTTTCGGGTCGCGACAACACACCGGATGCCGTGATGCCACTCTTTGACAAGGCCATTGAAGGGTTCGGCGAGCTGTT
CCGTTACCTGAGTTTCCAGGAGCTCGGCACCTCCACGGTGCAATCCCGCGCCTTGGGCGGCGTCGCCAACGGTACCGCCA
TTTTTTGCCTGCCCGGCTCCACCGGTGCCTGTCGCACCGCCTGGCGTGGCATACTCAGCGAACAACTGGATGCCCGCCAT
CGCCCCTGTAATTTTGTTGCCCATCTTAAATCCGCCAAGGAGTTGCCATCATCATGA

Upstream 100 bases:

>100_bases
GGGCATTACCGGAGTGACCCAGCATCTGGCGTCCATTGGCGGCTGAATTCAGCCGCTACCCCTGATCTGTTTCAGTTCAC
CCAGTGCCGAAGGAGACACC

Downstream 100 bases:

>100_bases
GTGCGTTTACCCATTTGAGTGACAAGGGCACGGCCCATATGGTGGACGTCACGGACAAAACCGTGACCGAGCGCGAAGCA
CGCGCCGAAGCTTACATAGA

Product: molybdenum cofactor biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MGHCRETEFKPLNIAVLTLSDTRDESNDTSGAFLADAVTEVGHKLVARRIIKDDKYLIRAQISAWIADPEVQVIISTGGT
GFSGRDNTPDAVMPLFDKAIEGFGELFRYLSFQELGTSTVQSRALGGVANGTAIFCLPGSTGACRTAWRGILSEQLDARH
RPCNFVAHLKSAKELPSS

Sequences:

>Translated_178_residues
MGHCRETEFKPLNIAVLTLSDTRDESNDTSGAFLADAVTEVGHKLVARRIIKDDKYLIRAQISAWIADPEVQVIISTGGT
GFSGRDNTPDAVMPLFDKAIEGFGELFRYLSFQELGTSTVQSRALGGVANGTAIFCLPGSTGACRTAWRGILSEQLDARH
RPCNFVAHLKSAKELPSS
>Mature_177_residues
GHCRETEFKPLNIAVLTLSDTRDESNDTSGAFLADAVTEVGHKLVARRIIKDDKYLIRAQISAWIADPEVQVIISTGGTG
FSGRDNTPDAVMPLFDKAIEGFGELFRYLSFQELGTSTVQSRALGGVANGTAIFCLPGSTGACRTAWRGILSEQLDARHR
PCNFVAHLKSAKELPSS

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=148, Percent_Identity=31.7567567567568, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI66932975, Length=148, Percent_Identity=31.7567567567568, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1787000, Length=164, Percent_Identity=59.7560975609756, Blast_Score=217, Evalue=3e-58,
Organism=Drosophila melanogaster, GI17136978, Length=145, Percent_Identity=34.4827586206897, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24638841, Length=145, Percent_Identity=34.4827586206897, Blast_Score=80, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 19257; Mature: 19126

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHCRETEFKPLNIAVLTLSDTRDESNDTSGAFLADAVTEVGHKLVARRIIKDDKYLIRA
CCCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
QISAWIADPEVQVIISTGGTGFSGRDNTPDAVMPLFDKAIEGFGELFRYLSFQELGTSTV
HHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSRALGGVANGTAIFCLPGSTGACRTAWRGILSEQLDARHRPCNFVAHLKSAKELPSS
HHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GHCRETEFKPLNIAVLTLSDTRDESNDTSGAFLADAVTEVGHKLVARRIIKDDKYLIRA
CCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
QISAWIADPEVQVIISTGGTGFSGRDNTPDAVMPLFDKAIEGFGELFRYLSFQELGTSTV
HHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSRALGGVANGTAIFCLPGSTGACRTAWRGILSEQLDARHRPCNFVAHLKSAKELPSS
HHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]