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The map label for this gene is moaC [H]

Identifier: 119776658

GI number: 119776658

Start: 4160879

End: 4161352

Strand: Direct

Name: moaC [H]

Synonym: Sama_3526

Alternate gene names: 119776658

Gene position: 4160879-4161352 (Clockwise)

Preceding gene: 119776657

Following gene: 119776659

Centisome position: 96.63

GC content: 56.12

Gene sequence:

>474_bases
ATGAGTGCGTTTACCCATTTGAGTGACAAGGGCACGGCCCATATGGTGGACGTCACGGACAAAACCGTGACCGAGCGCGA
AGCACGCGCCGAAGCTTACATAGAGATGGCCCCGTCCACCCTGGCGATGATCCTCGAAGGCAAGCATCACAAAGGTGACG
TATTTGCTACCGCCCGCATCGCCGGAATCATGGCCGCCAAGAAAACCTCCGACCTTATTCCCCTCTGCCACCCGCTTGCC
CTGACCAAGGTGGAGGTGGAACTGGAGCCCGAGCCGGAACAGAACCGGGTCAGAATTACCAGTTTGTGCAAGCTGTCAGG
AAAAACCGGAGTGGAAATGGAAGCCCTGACCGCCGCCTCTGTAGCCGCGCTGACCATTTACGATATGTGCAAGGCAGTCC
AGAAGGACATGGTGATCTCTCAGGTACGTCTTTTGGAAAAACGTGGCGGAAAATCCGGCCACTTCAAGGTGTAA

Upstream 100 bases:

>100_bases
GCACCGCCTGGCGTGGCATACTCAGCGAACAACTGGATGCCCGCCATCGCCCCTGTAATTTTGTTGCCCATCTTAAATCC
GCCAAGGAGTTGCCATCATC

Downstream 100 bases:

>100_bases
CTCATATGATTAATGTGCTTTTTTTTGCTCAGGTACGTGAGCTCTTGGGTGAATCCTCTCTGACACTCGATGCCGGTGAA
GGCACGGCAACCGCCGATGC

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MSAFTHLSDKGTAHMVDVTDKTVTEREARAEAYIEMAPSTLAMILEGKHHKGDVFATARIAGIMAAKKTSDLIPLCHPLA
LTKVEVELEPEPEQNRVRITSLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKV

Sequences:

>Translated_157_residues
MSAFTHLSDKGTAHMVDVTDKTVTEREARAEAYIEMAPSTLAMILEGKHHKGDVFATARIAGIMAAKKTSDLIPLCHPLA
LTKVEVELEPEPEQNRVRITSLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKV
>Mature_156_residues
SAFTHLSDKGTAHMVDVTDKTVTEREARAEAYIEMAPSTLAMILEGKHHKGDVFATARIAGIMAAKKTSDLIPLCHPLAL
TKVEVELEPEPEQNRVRITSLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKV

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=157, Percent_Identity=75.1592356687898, Blast_Score=242, Evalue=8e-66,
Organism=Caenorhabditis elegans, GI32566331, Length=151, Percent_Identity=41.0596026490066, Blast_Score=124, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28574490, Length=150, Percent_Identity=51.3333333333333, Blast_Score=148, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=52.5547445255474, Blast_Score=140, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17064; Mature: 16933

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFTHLSDKGTAHMVDVTDKTVTEREARAEAYIEMAPSTLAMILEGKHHKGDVFATARI
CCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHEEHHHCCCCCCCCEEHHHHH
AGIMAAKKTSDLIPLCHPLALTKVEVELEPEPEQNRVRITSLCKLSGKTGVEMEALTAAS
HHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEHEEEECCCCCCCHHHHHHHH
VAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SAFTHLSDKGTAHMVDVTDKTVTEREARAEAYIEMAPSTLAMILEGKHHKGDVFATARI
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHEEHHHCCCCCCCCEEHHHHH
AGIMAAKKTSDLIPLCHPLALTKVEVELEPEPEQNRVRITSLCKLSGKTGVEMEALTAAS
HHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEHEEEECCCCCCCHHHHHHHH
VAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]