Click here to switch to the map view.

The map label for this gene is moaA [H]

Identifier: 119776656

GI number: 119776656

Start: 4159269

End: 4160291

Strand: Direct

Name: moaA [H]

Synonym: Sama_3524

Alternate gene names: 119776656

Gene position: 4159269-4160291 (Clockwise)

Preceding gene: 119776652

Following gene: 119776657

Centisome position: 96.59

GC content: 54.06

Gene sequence:

>1023_bases
GTGCAGAAATGGCTTCACCTCCCGATACTTGGAAAGGTGATCATGTCTCAACTTCAAGACAGCTTTGGTCGTAAGTTTCA
CTATTTGCGGATGTCGGTTACCGACGTTTGCAACTTCAAATGCAGCTATTGTCTGCCCGACGGCTACCACCCGGATGGTA
GGCCGAGTTTTCTGACCCTCAGTGAAATCGAAAATCTGATTGCCGCCTTTGCCAAGGCCGGTACCCGCAAGGTGCGCATC
ACTGGCGGTGAGCCAACCCTGCGCAAAGATTTTACCGATATCATCCGGGTCATCGCAGACAACCAGGCCATCAGTACCCT
GGCCACCACCACCAACGGTTATCGCCTGGAGCAACACGCAAAAGAGTGGTTTGATGCGGGATTACGCCGTATCAATGTGT
CGGTGGACAGTCTCGACCCCAGAATGTTTTACCAGATAACGGGTGAAAACAAATTTGATACCGTGATGCGGGGTATTGAT
GCCGCGCTGAATGCTGGCTTCGAGCGGGTCAAGATTAACGCTGTGCTGCTCAAGGGGCTCAACGATAAAGATTTGCCACG
CTTCCTGCACTGGATCAAAAACACTCCCATCGATCTGCGTTTTATCGAGCTGATGGAAACCGGTCTTGGCCGCGATTATT
TCCAGGCCCACCATTTGCCCGGTAGCCAAATCAAGCAACAGCTGCTTGCCGATGGCTGGCAGTTGGATGAGCGCGGCGCC
GAAGATGGTCCGGCACAAAACTTCAGCCACAGCGATTATCAGGGCCGCATCGGGCTAATCATGCCCTATGAAAAGAACTT
CTGCGCCAGCTGTAACCGCCTGCGGGTGTCCGCCAAAGGCAAGCTGCATCTGTGCCTCTTCACTGAGCAGGGGCTGGATC
TCAGAGACCTGCTGCAAAGCCCAGAGCAACAACCCGCGCTGCTGGCAAGGCTGGAAGACCAGCTCAGGCTAAAAAAAGAA
ACCCATTTCCTGCATCAGGGCATTACCGGAGTGACCCAGCATCTGGCGTCCATTGGCGGCTGA

Upstream 100 bases:

>100_bases
TGCTTTAGGCCTATAATCCCTCAATGACGGTTCTCCGAGCTCCTGCACCTAAGTCAATGGATATGGTGTTTGAGCCGTGG
CGCGGTGCCACCGGGGTGGG

Downstream 100 bases:

>100_bases
ATTCAGCCGCTACCCCTGATCTGTTTCAGTTCACCCAGTGCCGAAGGAGACACCATGGGACACTGCCGCGAAACCGAATT
CAAACCCCTGAATATTGCTG

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MQKWLHLPILGKVIMSQLQDSFGRKFHYLRMSVTDVCNFKCSYCLPDGYHPDGRPSFLTLSEIENLIAAFAKAGTRKVRI
TGGEPTLRKDFTDIIRVIADNQAISTLATTTNGYRLEQHAKEWFDAGLRRINVSVDSLDPRMFYQITGENKFDTVMRGID
AALNAGFERVKINAVLLKGLNDKDLPRFLHWIKNTPIDLRFIELMETGLGRDYFQAHHLPGSQIKQQLLADGWQLDERGA
EDGPAQNFSHSDYQGRIGLIMPYEKNFCASCNRLRVSAKGKLHLCLFTEQGLDLRDLLQSPEQQPALLARLEDQLRLKKE
THFLHQGITGVTQHLASIGG

Sequences:

>Translated_340_residues
MQKWLHLPILGKVIMSQLQDSFGRKFHYLRMSVTDVCNFKCSYCLPDGYHPDGRPSFLTLSEIENLIAAFAKAGTRKVRI
TGGEPTLRKDFTDIIRVIADNQAISTLATTTNGYRLEQHAKEWFDAGLRRINVSVDSLDPRMFYQITGENKFDTVMRGID
AALNAGFERVKINAVLLKGLNDKDLPRFLHWIKNTPIDLRFIELMETGLGRDYFQAHHLPGSQIKQQLLADGWQLDERGA
EDGPAQNFSHSDYQGRIGLIMPYEKNFCASCNRLRVSAKGKLHLCLFTEQGLDLRDLLQSPEQQPALLARLEDQLRLKKE
THFLHQGITGVTQHLASIGG
>Mature_340_residues
MQKWLHLPILGKVIMSQLQDSFGRKFHYLRMSVTDVCNFKCSYCLPDGYHPDGRPSFLTLSEIENLIAAFAKAGTRKVRI
TGGEPTLRKDFTDIIRVIADNQAISTLATTTNGYRLEQHAKEWFDAGLRRINVSVDSLDPRMFYQITGENKFDTVMRGID
AALNAGFERVKINAVLLKGLNDKDLPRFLHWIKNTPIDLRFIELMETGLGRDYFQAHHLPGSQIKQQLLADGWQLDERGA
EDGPAQNFSHSDYQGRIGLIMPYEKNFCASCNRLRVSAKGKLHLCLFTEQGLDLRDLLQSPEQQPALLARLEDQLRLKKE
THFLHQGITGVTQHLASIGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI22027536, Length=311, Percent_Identity=35.6913183279743, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI116734668, Length=311, Percent_Identity=35.6913183279743, Blast_Score=192, Evalue=3e-49,
Organism=Escherichia coli, GI1786999, Length=329, Percent_Identity=60.4863221884498, Blast_Score=416, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI32566331, Length=307, Percent_Identity=34.5276872964169, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI32566329, Length=307, Percent_Identity=34.5276872964169, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17561210, Length=307, Percent_Identity=34.2019543973941, Blast_Score=179, Evalue=1e-45,
Organism=Drosophila melanogaster, GI28574490, Length=288, Percent_Identity=34.0277777777778, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI28574488, Length=288, Percent_Identity=34.0277777777778, Blast_Score=182, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 38552; Mature: 38552

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKWLHLPILGKVIMSQLQDSFGRKFHYLRMSVTDVCNFKCSYCLPDGYHPDGRPSFLTL
CCCEEECHHHHHHHHHHHHHHHCCEEEEEEEEHHHHHCCCEEEECCCCCCCCCCCCEEEH
SEIENLIAAFAKAGTRKVRITGGEPTLRKDFTDIIRVIADNQAISTLATTTNGYRLEQHA
HHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCEEHHHHH
KEWFDAGLRRINVSVDSLDPRMFYQITGENKFDTVMRGIDAALNAGFERVKINAVLLKGL
HHHHHHHHHEEEEEHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCHHHEEEEEEEEECC
NDKDLPRFLHWIKNTPIDLRFIELMETGLGRDYFQAHHLPGSQIKQQLLADGWQLDERGA
CCCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCC
EDGPAQNFSHSDYQGRIGLIMPYEKNFCASCNRLRVSAKGKLHLCLFTEQGLDLRDLLQS
CCCCCCCCCCCCCCCCEEEEECCCCCHHCCCCEEEEECCCCEEEEEEECCCCCHHHHHCC
PEQQPALLARLEDQLRLKKETHFLHQGITGVTQHLASIGG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQKWLHLPILGKVIMSQLQDSFGRKFHYLRMSVTDVCNFKCSYCLPDGYHPDGRPSFLTL
CCCEEECHHHHHHHHHHHHHHHCCEEEEEEEEHHHHHCCCEEEECCCCCCCCCCCCEEEH
SEIENLIAAFAKAGTRKVRITGGEPTLRKDFTDIIRVIADNQAISTLATTTNGYRLEQHA
HHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCEEHHHHH
KEWFDAGLRRINVSVDSLDPRMFYQITGENKFDTVMRGIDAALNAGFERVKINAVLLKGL
HHHHHHHHHEEEEEHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCHHHEEEEEEEEECC
NDKDLPRFLHWIKNTPIDLRFIELMETGLGRDYFQAHHLPGSQIKQQLLADGWQLDERGA
CCCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCC
EDGPAQNFSHSDYQGRIGLIMPYEKNFCASCNRLRVSAKGKLHLCLFTEQGLDLRDLLQS
CCCCCCCCCCCCCCCCEEEEECCCCCHHCCCCEEEEECCCCEEEEEEECCCCCHHHHHCC
PEQQPALLARLEDQLRLKKETHFLHQGITGVTQHLASIGG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA