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The map label for this gene is cheA [H]

Identifier: 119776627

GI number: 119776627

Start: 4124645

End: 4126732

Strand: Direct

Name: cheA [H]

Synonym: Sama_3495

Alternate gene names: 119776627

Gene position: 4124645-4126732 (Clockwise)

Preceding gene: 119776626

Following gene: 119776628

Centisome position: 95.79

GC content: 53.83

Gene sequence:

>2088_bases
ATGGACATAGATCTTAGCCAATTCAGTCAGGTGTTCTTCGAGGAAAGTATCGAGGGCCTGGCGATTATGGAGTCTGAGCT
GCTGAAGCTGGACGTGGCGGCGCCGGACCCAGAAACCATTAACACCATTTTCAGAGCAGCACACTCCATCAAAGGCGGCA
GTGCCACATTCGGTTTTATGCAGGTGGCCAACTACACCCATCTGCTTGAAACTCTGCTTGACGAAATCCGCGATGGTCGT
CGGCAGATGCAGCCTGACCATGTTGACATGCTGCTGCTTTCGGTGGATTTACTCAGGGGCATGTTCGAAGCCCTGATGAG
CCAAGCCGAATTCAACGACCCCAAGTTACCCGAGCTTGAGTTGCGGCTGAATAACACCCTGGCCAATCAACCAAGCCAAA
CGCAATCGATTTCTCCCCCTCAGGCAACAATGGCCTCAGACTCAAAAACGCTGTGCTGGCAGATTGATTTCAAGGCTGGC
GCAGACATTATGCGCTGCGGCAACGATCCCATGTTGATGTTTGCTGAGCTGGCCTCCAAGGGCACACTGACGGCCGAGCT
CCTGCCGGTTTCCTTTCCCGCATGGGACGACTTTGACCCCGAAGCCTGCTACCTGCACTGGCGCTTAAGATTGATCACAG
ACGAGCCACTGGAAAAACTCAAAGAGGTGTTCGAGTGGGTCGAAGATGAATGCGAAATCAGTTACCAACAAACAGCAGCA
GCCCCTTCTGCTGATACCTCCACAGAGATGCTGTCGCCATCACCACAATCCGAAGTCGACCCGCCTGTAGCAGCCCCTGA
TGTCATTGCGCTGACGCCCCAGGTTCAGGCTCTTGCCACAGACAAAGCCGTAGCCAGCCAAAAACAAAGCGCTGCAGCCG
CCAAGAGTGGAGAAAGCAGCTCCATCAGGGTCAGCACAGAAAAAATCGATATGCTCATCAATATGGTGGGTGAGCTGGTG
ATAACCCAAGCCATGCTGGGCCAAATAGGTCAACAGGATGAAATCAATCAGGAGTCGCTGTTACTGCTGCAACAGGGACT
AGAGCAGCTGGCTTCCCATACCCGGGATTTGCAGGAAAGTGTCATGCAGATTCGCATGCTGCCCATCAGCTTTGCGTTTA
ACCGCTTCCCCCGCTTGGTCAGAGACATTGGCCAGCAGCTGGGTAAGAAAGTAGAACTCATCCTCAAGGGTGAAGACACT
GAGCTGGATAAAACCGTCCTTGAAAAAATTGTCGACCCCATGGTGCATCTGGTGCGCAATTCGCTCGACCATGGGCTGGA
ATCACCCGAAGCCAGATTGGCACAGGGTAAGTCTGAAACCGGCACCATCATGCTCAATGCCTATCATCAGGGCGGCTGCA
TCATCATAGAAATAGCGGACGATGGCGCCGGGCTGAACACCCACAAGATCCTTGAAAAAGCCCGTCAAAAAGGGCTGGTC
GGCGCCGAGGAAGAGTTATCGGAAGAAGCCATCCACCAGCTGATATTCAGACCTGGCTTTTCCACCGCCGATGCAGTGTC
AGACCTCTCAGGGCGTGGCGTGGGCATGGATGTGGTCAAGCGCAATATTCACGAGCTCAATGGCTCCATTGAATTGAAAT
CCGAGGCGGGTAAAGGCAGCCGTTTCACCATTCGACTTCCCCTGACGCTGGCCATACTCGACGGCCAGCTTATCCGCATC
GGCAAGCACATATACGTGGTGCCACTGGTGTCCATCTACGAATCGTTGCAGGTGCCCACCAACCGTATCAATCGGCTGTC
CGATGGCCATGAGCTGATCCGTCTGCGGGATGAATATTTACCGGTAATCAAGATGTATCGAGAGTTCAACCACGATGCTG
ACGCGCGGGAAATCAAAGATGGCCTGGTGATGGTAGTGGATCATAACAATGAAAAGGCCGGCCTGCTGGTGGACGAACTT
CTCGCGCAACAACAGGTTGTAATCAAAAGCCTGGAGGAGAACTACACCCGTATTCCGGGCATTTCGGGCGCCACCATACT
GGGCGACGGCACAGTCGCACTCATCATAGACGTTGCCGGACTGGTCAAGTTGGCCGGTATAGGCAGCAGCAATGAACACG
CCGCGTAA

Upstream 100 bases:

>100_bases
GCAGCAGGAGCTACAGGTTGGATTGTGAAACCCTTTAATCCGGAACAGTTGCTGGCCACAGTGCGCAAAGTGTTGGGATA
ACCCGCAGAGAGACTAGGGA

Downstream 100 bases:

>100_bases
AAAGGAAGACTCGATATGGCTGACATTTCCATCGAACAGGTCAAGCAGGGTAATCAACAGTATCTGAGCTTCATCATGGC
CAACGAGGAGTACGGCGTGG

Product: putative CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 695; Mature: 695

Protein sequence:

>695_residues
MDIDLSQFSQVFFEESIEGLAIMESELLKLDVAAPDPETINTIFRAAHSIKGGSATFGFMQVANYTHLLETLLDEIRDGR
RQMQPDHVDMLLLSVDLLRGMFEALMSQAEFNDPKLPELELRLNNTLANQPSQTQSISPPQATMASDSKTLCWQIDFKAG
ADIMRCGNDPMLMFAELASKGTLTAELLPVSFPAWDDFDPEACYLHWRLRLITDEPLEKLKEVFEWVEDECEISYQQTAA
APSADTSTEMLSPSPQSEVDPPVAAPDVIALTPQVQALATDKAVASQKQSAAAAKSGESSSIRVSTEKIDMLINMVGELV
ITQAMLGQIGQQDEINQESLLLLQQGLEQLASHTRDLQESVMQIRMLPISFAFNRFPRLVRDIGQQLGKKVELILKGEDT
ELDKTVLEKIVDPMVHLVRNSLDHGLESPEARLAQGKSETGTIMLNAYHQGGCIIIEIADDGAGLNTHKILEKARQKGLV
GAEEELSEEAIHQLIFRPGFSTADAVSDLSGRGVGMDVVKRNIHELNGSIELKSEAGKGSRFTIRLPLTLAILDGQLIRI
GKHIYVVPLVSIYESLQVPTNRINRLSDGHELIRLRDEYLPVIKMYREFNHDADAREIKDGLVMVVDHNNEKAGLLVDEL
LAQQQVVIKSLEENYTRIPGISGATILGDGTVALIIDVAGLVKLAGIGSSNEHAA

Sequences:

>Translated_695_residues
MDIDLSQFSQVFFEESIEGLAIMESELLKLDVAAPDPETINTIFRAAHSIKGGSATFGFMQVANYTHLLETLLDEIRDGR
RQMQPDHVDMLLLSVDLLRGMFEALMSQAEFNDPKLPELELRLNNTLANQPSQTQSISPPQATMASDSKTLCWQIDFKAG
ADIMRCGNDPMLMFAELASKGTLTAELLPVSFPAWDDFDPEACYLHWRLRLITDEPLEKLKEVFEWVEDECEISYQQTAA
APSADTSTEMLSPSPQSEVDPPVAAPDVIALTPQVQALATDKAVASQKQSAAAAKSGESSSIRVSTEKIDMLINMVGELV
ITQAMLGQIGQQDEINQESLLLLQQGLEQLASHTRDLQESVMQIRMLPISFAFNRFPRLVRDIGQQLGKKVELILKGEDT
ELDKTVLEKIVDPMVHLVRNSLDHGLESPEARLAQGKSETGTIMLNAYHQGGCIIIEIADDGAGLNTHKILEKARQKGLV
GAEEELSEEAIHQLIFRPGFSTADAVSDLSGRGVGMDVVKRNIHELNGSIELKSEAGKGSRFTIRLPLTLAILDGQLIRI
GKHIYVVPLVSIYESLQVPTNRINRLSDGHELIRLRDEYLPVIKMYREFNHDADAREIKDGLVMVVDHNNEKAGLLVDEL
LAQQQVVIKSLEENYTRIPGISGATILGDGTVALIIDVAGLVKLAGIGSSNEHAA
>Mature_695_residues
MDIDLSQFSQVFFEESIEGLAIMESELLKLDVAAPDPETINTIFRAAHSIKGGSATFGFMQVANYTHLLETLLDEIRDGR
RQMQPDHVDMLLLSVDLLRGMFEALMSQAEFNDPKLPELELRLNNTLANQPSQTQSISPPQATMASDSKTLCWQIDFKAG
ADIMRCGNDPMLMFAELASKGTLTAELLPVSFPAWDDFDPEACYLHWRLRLITDEPLEKLKEVFEWVEDECEISYQQTAA
APSADTSTEMLSPSPQSEVDPPVAAPDVIALTPQVQALATDKAVASQKQSAAAAKSGESSSIRVSTEKIDMLINMVGELV
ITQAMLGQIGQQDEINQESLLLLQQGLEQLASHTRDLQESVMQIRMLPISFAFNRFPRLVRDIGQQLGKKVELILKGEDT
ELDKTVLEKIVDPMVHLVRNSLDHGLESPEARLAQGKSETGTIMLNAYHQGGCIIIEIADDGAGLNTHKILEKARQKGLV
GAEEELSEEAIHQLIFRPGFSTADAVSDLSGRGVGMDVVKRNIHELNGSIELKSEAGKGSRFTIRLPLTLAILDGQLIRI
GKHIYVVPLVSIYESLQVPTNRINRLSDGHELIRLRDEYLPVIKMYREFNHDADAREIKDGLVMVVDHNNEKAGLLVDEL
LAQQQVVIKSLEENYTRIPGISGATILGDGTVALIIDVAGLVKLAGIGSSNEHAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=710, Percent_Identity=40.7042253521127, Blast_Score=494, Evalue=1e-141,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76479; Mature: 76479

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIDLSQFSQVFFEESIEGLAIMESELLKLDVAAPDPETINTIFRAAHSIKGGSATFGFM
CCCCHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHH
QVANYTHLLETLLDEIRDGRRQMQPDHVDMLLLSVDLLRGMFEALMSQAEFNDPKLPELE
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
LRLNNTLANQPSQTQSISPPQATMASDSKTLCWQIDFKAGADIMRCGNDPMLMFAELASK
EEECCHHCCCCCCCCCCCCCCHHHCCCCCEEEEEEECCCCCHHHHCCCCCHHHHHHHHCC
GTLTAELLPVSFPAWDDFDPEACYLHWRLRLITDEPLEKLKEVFEWVEDECEISYQQTAA
CCEEEEEEEEECCCCCCCCCCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHCC
APSADTSTEMLSPSPQSEVDPPVAAPDVIALTPQVQALATDKAVASQKQSAAAAKSGESS
CCCCCCCHHHCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCC
SIRVSTEKIDMLINMVGELVITQAMLGQIGQQDEINQESLLLLQQGLEQLASHTRDLQES
EEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VMQIRMLPISFAFNRFPRLVRDIGQQLGKKVELILKGEDTELDKTVLEKIVDPMVHLVRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
SLDHGLESPEARLAQGKSETGTIMLNAYHQGGCIIIEIADDGAGLNTHKILEKARQKGLV
HHHCCCCCCHHHHHCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCCC
GAEEELSEEAIHQLIFRPGFSTADAVSDLSGRGVGMDVVKRNIHELNGSIELKSEAGKGS
CCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCC
RFTIRLPLTLAILDGQLIRIGKHIYVVPLVSIYESLQVPTNRINRLSDGHELIRLRDEYL
EEEEEEEEEEEEECCCEEEECCEEEEEEHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHH
PVIKMYREFNHDADAREIKDGLVMVVDHNNEKAGLLVDELLAQQQVVIKSLEENYTRIPG
HHHHHHHHHCCCCCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
ISGATILGDGTVALIIDVAGLVKLAGIGSSNEHAA
CCCCEEECCCCEEEHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDIDLSQFSQVFFEESIEGLAIMESELLKLDVAAPDPETINTIFRAAHSIKGGSATFGFM
CCCCHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHH
QVANYTHLLETLLDEIRDGRRQMQPDHVDMLLLSVDLLRGMFEALMSQAEFNDPKLPELE
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
LRLNNTLANQPSQTQSISPPQATMASDSKTLCWQIDFKAGADIMRCGNDPMLMFAELASK
EEECCHHCCCCCCCCCCCCCCHHHCCCCCEEEEEEECCCCCHHHHCCCCCHHHHHHHHCC
GTLTAELLPVSFPAWDDFDPEACYLHWRLRLITDEPLEKLKEVFEWVEDECEISYQQTAA
CCEEEEEEEEECCCCCCCCCCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHCC
APSADTSTEMLSPSPQSEVDPPVAAPDVIALTPQVQALATDKAVASQKQSAAAAKSGESS
CCCCCCCHHHCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCC
SIRVSTEKIDMLINMVGELVITQAMLGQIGQQDEINQESLLLLQQGLEQLASHTRDLQES
EEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VMQIRMLPISFAFNRFPRLVRDIGQQLGKKVELILKGEDTELDKTVLEKIVDPMVHLVRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
SLDHGLESPEARLAQGKSETGTIMLNAYHQGGCIIIEIADDGAGLNTHKILEKARQKGLV
HHHCCCCCCHHHHHCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCCC
GAEEELSEEAIHQLIFRPGFSTADAVSDLSGRGVGMDVVKRNIHELNGSIELKSEAGKGS
CCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCC
RFTIRLPLTLAILDGQLIRIGKHIYVVPLVSIYESLQVPTNRINRLSDGHELIRLRDEYL
EEEEEEEEEEEEECCCEEEECCEEEEEEHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHH
PVIKMYREFNHDADAREIKDGLVMVVDHNNEKAGLLVDELLAQQQVVIKSLEENYTRIPG
HHHHHHHHHCCCCCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
ISGATILGDGTVALIIDVAGLVKLAGIGSSNEHAA
CCCCEEECCCCEEEHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2002011; 9097040; 9278503; 3510184; 2832069; 2068106; 8555213; 8639521; 9020767; 9437425; 9636149 [H]