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The map label for this gene is cheW [H]

Identifier: 119776628

GI number: 119776628

Start: 4126748

End: 4127287

Strand: Direct

Name: cheW [H]

Synonym: Sama_3496

Alternate gene names: 119776628

Gene position: 4126748-4127287 (Clockwise)

Preceding gene: 119776627

Following gene: 119776629

Centisome position: 95.83

GC content: 52.59

Gene sequence:

>540_bases
ATGGCTGACATTTCCATCGAACAGGTCAAGCAGGGTAATCAACAGTATCTGAGCTTCATCATGGCCAACGAGGAGTACGG
CGTGGACATCCTCTCCGTACAGGAAATCCGCGGCTGGGAACCCACCACTGTGCTGCCAAACGCCCCCGACTATGTCAAAG
GCGTCATCAACTTGCGGGGCACCATAGTCCCCATCATAGATCTGCGGCAAAAGTTTGGGATAAAGACCCTGGAATATGGC
GCAACCACTGTGGTGATAGTGGTCAAGGTGACCATGGATGAAACCCAAAAGGTGATAGGCATAGTGGTAGATGCCGTATC
AGACGTGTTCAGCATCGAAGAAGAAGAAATCCGCCAGGCCCCTGACTTTGGTCACGGCACCGACCTGCGGTTCATCAAGG
GGCTGGCAAATGTGCAGGACAAGATGGTCATTCTGCTTGAGATCAACCGGTTACTTGGCTCCGCCATCTTACCGGATCCC
GAGACACTGAATCGGATCATCGGCAATCTCGAACAACAAGCTCAGGTAATGACTGCCTGA

Upstream 100 bases:

>100_bases
CGACGGCACAGTCGCACTCATCATAGACGTTGCCGGACTGGTCAAGTTGGCCGGTATAGGCAGCAGCAATGAACACGCCG
CGTAAAAAGGAAGACTCGAT

Downstream 100 bases:

>100_bases
AATGGACACTAAAGCAAGAGGAATCAACATGGACGCAGGCAATAAAAAGCTGATGGGGCCAGCCCCATTTACCTTGGCCG
GCATGGTGATAGTTGCCGTT

Product: biotin synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MADISIEQVKQGNQQYLSFIMANEEYGVDILSVQEIRGWEPTTVLPNAPDYVKGVINLRGTIVPIIDLRQKFGIKTLEYG
ATTVVIVVKVTMDETQKVIGIVVDAVSDVFSIEEEEIRQAPDFGHGTDLRFIKGLANVQDKMVILLEINRLLGSAILPDP
ETLNRIIGNLEQQAQVMTA

Sequences:

>Translated_179_residues
MADISIEQVKQGNQQYLSFIMANEEYGVDILSVQEIRGWEPTTVLPNAPDYVKGVINLRGTIVPIIDLRQKFGIKTLEYG
ATTVVIVVKVTMDETQKVIGIVVDAVSDVFSIEEEEIRQAPDFGHGTDLRFIKGLANVQDKMVILLEINRLLGSAILPDP
ETLNRIIGNLEQQAQVMTA
>Mature_178_residues
ADISIEQVKQGNQQYLSFIMANEEYGVDILSVQEIRGWEPTTVLPNAPDYVKGVINLRGTIVPIIDLRQKFGIKTLEYGA
TTVVIVVKVTMDETQKVIGIVVDAVSDVFSIEEEEIRQAPDFGHGTDLRFIKGLANVQDKMVILLEINRLLGSAILPDPE
TLNRIIGNLEQQAQVMTA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=154, Percent_Identity=45.4545454545455, Blast_Score=137, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 19852; Mature: 19721

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADISIEQVKQGNQQYLSFIMANEEYGVDILSVQEIRGWEPTTVLPNAPDYVKGVINLRG
CCCCCHHHHHCCCHHHHHHHHCCCCCCCEEEEHHHHCCCCCCCCCCCCHHHHHHHHHCCC
TIVPIIDLRQKFGIKTLEYGATTVVIVVKVTMDETQKVIGIVVDAVSDVFSIEEEEIRQA
CEEHHHHHHHHHCCCEEECCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHCC
PDFGHGTDLRFIKGLANVQDKMVILLEINRLLGSAILPDPETLNRIIGNLEQQAQVMTA
CCCCCCCCHHHHHHHHCHHHHEEHEEEHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHCC
>Mature Secondary Structure 
ADISIEQVKQGNQQYLSFIMANEEYGVDILSVQEIRGWEPTTVLPNAPDYVKGVINLRG
CCCCHHHHHCCCHHHHHHHHCCCCCCCEEEEHHHHCCCCCCCCCCCCHHHHHHHHHCCC
TIVPIIDLRQKFGIKTLEYGATTVVIVVKVTMDETQKVIGIVVDAVSDVFSIEEEEIRQA
CEEHHHHHHHHHCCCEEECCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHCC
PDFGHGTDLRFIKGLANVQDKMVILLEINRLLGSAILPDPETLNRIIGNLEQQAQVMTA
CCCCCCCCHHHHHHHHCHHHHEEHEEEHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]