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The map label for this gene is ydhC [C]

Identifier: 119776439

GI number: 119776439

Start: 3935845

End: 3936990

Strand: Reverse

Name: ydhC [C]

Synonym: Sama_3307

Alternate gene names: 119776439

Gene position: 3936990-3935845 (Counterclockwise)

Preceding gene: 119776442

Following gene: 119776438

Centisome position: 91.43

GC content: 57.33

Gene sequence:

>1146_bases
ATGAAAACTAAACCTTCTTTGTGGCTGATGCTGCTGTTATTGATGTTTCCACAAATAGTAGAAACCCTTTACAGCCCGGC
ATTGGTGTCGATTTCGCAGGCGTTTGCTGTCTCTGATACCGAGGCATCACAGACTCTGTCGATTTACTTTATTGCCTTTG
CCCTCGGGGTCGCGGTATGGGGCATAGTGGCCGATGCCTGGGGCCGACGGCCGACCATGTTGTTGGGGCTGAGTGTCTAT
GGCATCTCGGCGTTGGTTGCATTGCAAACCGACAGTTTCGCCGTGCTCATGCTGGCCAGAGCCTGCAGCGCCTTTGGGAT
TGCCGTTGGCTCCATTGTGACCCAAACCATGCTGCGGGACAGCTTTGATGGGGATGCGCTGGGCAAGGTATTCAGCCTGA
TGGGGCTCGGCATCGCCCTGAGTCCCGTCATAGGTATGTTTACCGGCGGCCAATTGGTGCTGCTCGGTGGCCATGGCGCG
GTGTTTACGTTGCTGTTATTCATGGCACTGGTACTGCTTGGCTGCTGTGTGCGTTTTTTACCGGAGACGTTTCCCGAAAC
TGTTACCCGGACTCAGGGCACGAATCAGTCGTTTCCGTTATCGGCGCTGGCAAAGCGAATGTTGGCAGATTGGCACATCT
GGCGCTCGGCGCTGCTGGTCGCCATCTATAACATCGGCTTGTTCAGCTATTACCAATTGGGCGGATTTGCCTTTGCCCGG
TTGGGGTTGACCCCGGAGGTGTTCGGTTACAGCGGCCTGCTGCTGGGGCTGGGTTCCTGCGTCGGCAGTTATCTCAATAG
CAGGCTGATTGCCAATGAGGTCAGTCTACAGCGACGGCTTCTCGGGGCGGCAACCCTGCTGCTGTTGGGCGCTGTTTCCC
TGTGCCTGCTGCAGGGCAGTGTCTGGTTTGTGCTGCCTATGTGCCTGGTGGTGATGGCATTCGGGGTGGCTATCCCCAAT
GTGCTGAGTATGGCCCTGAGTGACTATAAGATGTATGCAGGCAGTGCCGGTGCCCTGCTTGGCCTGATGTACTACCTGCT
TATCGGCGCTGGCCTGGCACTGGCCGGGTTAATAGAGCACCTTGGCTGGGTGCTGCTTGGCTGCGCCGTCGCGGCCTGGG
CCGTTACGCTTATCCACCGCCGCTAA

Upstream 100 bases:

>100_bases
TTGTGTCCTTATTTAAATGTTTTTGGTCTGAATGTTGATAATTGGCTGTGGTGAATTAAGTCTACACTGCCCGCAAACGT
AAGTCAGGGTGGCAGATTGG

Downstream 100 bases:

>100_bases
CTGGCCCACGCCAATAATCAACGGGAGCCAACTGGCGTTGAGTGTGCCGCGCCCAAAGCAGCTACAGCGCCTTGCTCCCC
ATCAACCTTTGTTGTACCTT

Product: multidrug resistance protein D

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKTKPSLWLMLLLLMFPQIVETLYSPALVSISQAFAVSDTEASQTLSIYFIAFALGVAVWGIVADAWGRRPTMLLGLSVY
GISALVALQTDSFAVLMLARACSAFGIAVGSIVTQTMLRDSFDGDALGKVFSLMGLGIALSPVIGMFTGGQLVLLGGHGA
VFTLLLFMALVLLGCCVRFLPETFPETVTRTQGTNQSFPLSALAKRMLADWHIWRSALLVAIYNIGLFSYYQLGGFAFAR
LGLTPEVFGYSGLLLGLGSCVGSYLNSRLIANEVSLQRRLLGAATLLLLGAVSLCLLQGSVWFVLPMCLVVMAFGVAIPN
VLSMALSDYKMYAGSAGALLGLMYYLLIGAGLALAGLIEHLGWVLLGCAVAAWAVTLIHRR

Sequences:

>Translated_381_residues
MKTKPSLWLMLLLLMFPQIVETLYSPALVSISQAFAVSDTEASQTLSIYFIAFALGVAVWGIVADAWGRRPTMLLGLSVY
GISALVALQTDSFAVLMLARACSAFGIAVGSIVTQTMLRDSFDGDALGKVFSLMGLGIALSPVIGMFTGGQLVLLGGHGA
VFTLLLFMALVLLGCCVRFLPETFPETVTRTQGTNQSFPLSALAKRMLADWHIWRSALLVAIYNIGLFSYYQLGGFAFAR
LGLTPEVFGYSGLLLGLGSCVGSYLNSRLIANEVSLQRRLLGAATLLLLGAVSLCLLQGSVWFVLPMCLVVMAFGVAIPN
VLSMALSDYKMYAGSAGALLGLMYYLLIGAGLALAGLIEHLGWVLLGCAVAAWAVTLIHRR
>Mature_381_residues
MKTKPSLWLMLLLLMFPQIVETLYSPALVSISQAFAVSDTEASQTLSIYFIAFALGVAVWGIVADAWGRRPTMLLGLSVY
GISALVALQTDSFAVLMLARACSAFGIAVGSIVTQTMLRDSFDGDALGKVFSLMGLGIALSPVIGMFTGGQLVLLGGHGA
VFTLLLFMALVLLGCCVRFLPETFPETVTRTQGTNQSFPLSALAKRMLADWHIWRSALLVAIYNIGLFSYYQLGGFAFAR
LGLTPEVFGYSGLLLGLGSCVGSYLNSRLIANEVSLQRRLLGAATLLLLGAVSLCLLQGSVWFVLPMCLVVMAFGVAIPN
VLSMALSDYKMYAGSAGALLGLMYYLLIGAGLALAGLIEHLGWVLLGCAVAAWAVTLIHRR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=330, Percent_Identity=23.9393939393939, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI87082312, Length=175, Percent_Identity=29.1428571428571, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788509, Length=375, Percent_Identity=24.8, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 40573; Mature: 40573

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKPSLWLMLLLLMFPQIVETLYSPALVSISQAFAVSDTEASQTLSIYFIAFALGVAVW
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
GIVADAWGRRPTMLLGLSVYGISALVALQTDSFAVLMLARACSAFGIAVGSIVTQTMLRD
HHHHHHCCCCCHHEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SFDGDALGKVFSLMGLGIALSPVIGMFTGGQLVLLGGHGAVFTLLLFMALVLLGCCVRFL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
PETFPETVTRTQGTNQSFPLSALAKRMLADWHIWRSALLVAIYNIGLFSYYQLGGFAFAR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLTPEVFGYSGLLLGLGSCVGSYLNSRLIANEVSLQRRLLGAATLLLLGAVSLCLLQGS
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VWFVLPMCLVVMAFGVAIPNVLSMALSDYKMYAGSAGALLGLMYYLLIGAGLALAGLIEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGWVLLGCAVAAWAVTLIHRR
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA