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The map label for this gene is actR [H]

Identifier: 119776318

GI number: 119776318

Start: 3778333

End: 3778869

Strand: Reverse

Name: actR [H]

Synonym: Sama_3186

Alternate gene names: 119776318

Gene position: 3778869-3778333 (Counterclockwise)

Preceding gene: 119776319

Following gene: 119776317

Centisome position: 87.76

GC content: 58.47

Gene sequence:

>537_bases
ATGAGCATGATGCCTAAATTGTTGATTATTGAAGATGATATGGCCTATGGTGCCGTACTCAGTCGCCGCATGAGTCGGCA
GGGATTTGAATGTCGCCATGTCAGTGAGCCCACGGATGCACTCCTGTGCGCCCGTCAGTGGCATCCAAGCCATGTGTTAC
TGGACATGAAGCTTGAAGACAGCAATGGTCTCAAACTCCTGCCACCGCTGCGGGGCAGCTTACCCCGGGCCACCATAGTG
CTGCTGACCGGTTTCGCCAGCATTGCCACCGCGGTGGAGGCGGTTAAGGCCGGTGCCGATAATTATCTCGCCAAGCCTGC
CGACACCCGCACCCTGATGGCGGCCCTGATGCCCGGCGCAACTGCGCCAAATGATGAGGTTGTGGCCGAAGATGTGCCGA
TGAACCCGAGGCGGCTCGAATGGGAGCATTTACAGCAGGTGCTGTCTGCCAACGAGGGTAATGTGTCGGCCACGGCGCGT
CAGCTCGGTATGCACAGGCGCACCCTGCAGCGAAAACTCGCCAAAAAGCCAGCATGA

Upstream 100 bases:

>100_bases
GCCACGCCAGTCTTGAGCGTCTCGGCGGCGAGCTGCATTTGGGGAACCTGCCTGAGGGAGGTTGTCTTGCCAGCGTGCGC
TTGCCTCTGGAGCAGAGCTC

Downstream 100 bases:

>100_bases
GGCAAAGGCGGTTTTGTTCCTGAGTTGCTGAGTAGAAACGAACTCCACGGGCGTTGAACGAACATAAAAAAAGCCCCGGG
TGGCATTCCCCGGGGTGGTT

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MSMMPKLLIIEDDMAYGAVLSRRMSRQGFECRHVSEPTDALLCARQWHPSHVLLDMKLEDSNGLKLLPPLRGSLPRATIV
LLTGFASIATAVEAVKAGADNYLAKPADTRTLMAALMPGATAPNDEVVAEDVPMNPRRLEWEHLQQVLSANEGNVSATAR
QLGMHRRTLQRKLAKKPA

Sequences:

>Translated_178_residues
MSMMPKLLIIEDDMAYGAVLSRRMSRQGFECRHVSEPTDALLCARQWHPSHVLLDMKLEDSNGLKLLPPLRGSLPRATIV
LLTGFASIATAVEAVKAGADNYLAKPADTRTLMAALMPGATAPNDEVVAEDVPMNPRRLEWEHLQQVLSANEGNVSATAR
QLGMHRRTLQRKLAKKPA
>Mature_177_residues
SMMPKLLIIEDDMAYGAVLSRRMSRQGFECRHVSEPTDALLCARQWHPSHVLLDMKLEDSNGLKLLPPLRGSLPRATIVL
LTGFASIATAVEAVKAGADNYLAKPADTRTLMAALMPGATAPNDEVVAEDVPMNPRRLEWEHLQQVLSANEGNVSATARQ
LGMHRRTLQRKLAKKPA

Specific function: Member of the two-component regulatory system ActS/ActR acting in acid tolerance. These data implicate that a two- component sensor may be involved in pH sensing and/or response [H]

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=151, Percent_Identity=29.1390728476821, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1789809, Length=136, Percent_Identity=30.1470588235294, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790437, Length=110, Percent_Identity=29.0909090909091, Blast_Score=60, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 19561; Mature: 19430

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMMPKLLIIEDDMAYGAVLSRRMSRQGFECRHVSEPTDALLCARQWHPSHVLLDMKLED
CCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEECC
SNGLKLLPPLRGSLPRATIVLLTGFASIATAVEAVKAGADNYLAKPADTRTLMAALMPGA
CCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCC
TAPNDEVVAEDVPMNPRRLEWEHLQQVLSANEGNVSATARQLGMHRRTLQRKLAKKPA
CCCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SMMPKLLIIEDDMAYGAVLSRRMSRQGFECRHVSEPTDALLCARQWHPSHVLLDMKLED
CCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEECC
SNGLKLLPPLRGSLPRATIVLLTGFASIATAVEAVKAGADNYLAKPADTRTLMAALMPGA
CCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCC
TAPNDEVVAEDVPMNPRRLEWEHLQQVLSANEGNVSATARQLGMHRRTLQRKLAKKPA
CCCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]