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The map label for this gene is hlyB [H]

Identifier: 119775954

GI number: 119775954

Start: 3360728

End: 3362749

Strand: Direct

Name: hlyB [H]

Synonym: Sama_2822

Alternate gene names: 119775954

Gene position: 3360728-3362749 (Clockwise)

Preceding gene: 119775953

Following gene: 119775962

Centisome position: 78.04

GC content: 53.56

Gene sequence:

>2022_bases
ATGAAAATCAAAGTCGCCACCAGAGTCATTGGCGGGTTCAGTTTTGTTACCCTTCTGTTGGTCATACTCGGTGGCGCCTC
GCTGGTCACCAACAACAATCTCAAAGACAGCACCGCCATCATGCAGGAGTTGAGTATGCCTGCACTGGAGGCCACAGGGC
ATCTTTCCGAAACCCTCAGCGAACAGCAGCGGCTTATCCTCAAAGCTTTCCACAGTAAAAATTCTTCGACCGTGCCTGGG
CTGGAAAGAACATTCGATCAGCTCAGCAGTGGCTTCAACAACCAATTTACCCTGCTTTCCGGCCTGCTCAATAACCGTGA
TAATTTTCAGGGACAGCTTAGCGGCCTGAGCAGCAGTTATCAGGTGCTGGAAAGTAATAGCAAGGCCATGCTTAAAGCCC
GCTTTGACTCGCTCTCGCAGCAGGAAGAACTGCTCAAGCTGCGCGAGAAGCTGGAAAACAGTGCCGACGACGCCTCTTCC
AATCTGTTTGATCTTATCGATTTGGAAAGCAGCCAAAACCAAACTGAGCGTGAGATTGCCGCTGCCGCTGGCGCCATAGA
TACCACCATGACGGGTATCATCACGACAGTTTACGACCTGGTCGCCGCCGAAGAGCGCAGCAAGTATGAACTCATCTCCA
AAGAGCTCGACTATATGCTCGGCGAAGTGAAGACCAAGATGGAGTACATTTCCCGCCACGGTGAAGGCATTATTGATGCC
GACCTGGTCAGCACCCTCAATGATGACAGCACCAAGGTGCTGAAAATGTTGGAAGGCAAGGACACTCTGGTCACCCTCAA
GTCCCGCCAGATAGACAGTACTCAGCTGACCTCTGAGAAACTGACCCTGGTGGAAAAGAATGCGCTGACAGTTACAGAGC
AGATGAAGCGTCTAGCCAAAGATATCGAAACTGTCACCAACGACATCAGCAATCAGGCCCTGAACGACATCAACAGTGCC
TCTCTCAGAACACTGATCCTGGTGGTGATTGCCATCGTTGTGGCCGTGGTCATCAGTTTTGCCGTGGTGAGACCACTGAA
ACGCTCGCTGGATGAGGTGAACGGTGCCCTCAATGTGTTGGCATCCGGCGACCTCACTCACAAGCTGGACGACACCGGCC
ACGATGAATTTGCCGAGCTGTCCCGCAACTGTAACCGTTTGGTCGACAGCCTGCGCAGCCTGATTGCCAGTATCCTCGAC
CGTTCAAACCAACTGGCTGCAGCCGCCGAAGAAACCTCTGCCATTACCTCTCAAACTACCATAGGTATTCAGGAACAGAA
GAGCCAGGTTGACCAGGTTGCAACGGCTACCACTGAGCTAAGCTCCAGTGCCCATCAGGTGAACATGAGCGCCGATGACG
CCTTGAGCCAGATTAAGCAAGCCGACGAAGAAACCCAGCACATGCGCACCATTGCCGATGAAAACAAGCGCACCATTTTG
TCGCTGGCAGATGAAGTGGCCAAGGCCAGCAAGGTGATCAACAAGGTGCATTCTGACAGTGCCTCTATCGGCTCAATTCT
GGATGTTATCCGGGGCATTGCCGAGCAGACCAATTTGTTGGCACTCAACGCCGCCATTGAAGCCGCCCGTGCCGGTGAGC
AGGGACGTGGCTTTGCCGTCGTGGCCGACGAAGTTCGTAGCCTGGCGTCCCGTACCCAGGACTCTACCCGAGAAATTCAG
CAAATGATTGAAGTGCTGCAGCAAGGCACTCAACAGGCTGTGGCCGTGATGCAGTTGGGGCAAAATCAGGCACAAAGCTG
TGTGGAGAAAACCGAGCAAGCCAACCAGGCGCTGCAAACCATCAGCCACTCTGTGCATAAAGCCTATGATGCCGGCACTC
ACATTGCTCAGGCGGCACAGGAGCAGAATCTGGTCAGCCAGCAAGTTTCTGAGAAACTGGAACACATTGCCGCTATTTCC
GAAGAGACTGCGCTAGGTGCAGAGCAAACAGCCAAGTCCAGCCACGAGGTGGCACGCCTTGCCGAAGAGCTGCAAAGCTC
GGTGAAAGAGTTTAGGGTGTAA

Upstream 100 bases:

>100_bases
AAACTAAAGCTCGAAGAGGCCGATACAAAAGGGCCGCGCGTCAAAGCTCCATACTGCTTTCTGATTCGGGAAAAAAACTA
AAACATCGCCGGAGTGTCCT

Downstream 100 bases:

>100_bases
GACACTCGTCTACAGCCCCCTTTGAAAGCCCCTGTGTGGGGCTTTTTTATTGCCAGTTCTGCCACCGCAGAAAGCCTTCA
GCCCCTGTGGAAGTGGCTTT

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 673; Mature: 673

Protein sequence:

>673_residues
MKIKVATRVIGGFSFVTLLLVILGGASLVTNNNLKDSTAIMQELSMPALEATGHLSETLSEQQRLILKAFHSKNSSTVPG
LERTFDQLSSGFNNQFTLLSGLLNNRDNFQGQLSGLSSSYQVLESNSKAMLKARFDSLSQQEELLKLREKLENSADDASS
NLFDLIDLESSQNQTEREIAAAAGAIDTTMTGIITTVYDLVAAEERSKYELISKELDYMLGEVKTKMEYISRHGEGIIDA
DLVSTLNDDSTKVLKMLEGKDTLVTLKSRQIDSTQLTSEKLTLVEKNALTVTEQMKRLAKDIETVTNDISNQALNDINSA
SLRTLILVVIAIVVAVVISFAVVRPLKRSLDEVNGALNVLASGDLTHKLDDTGHDEFAELSRNCNRLVDSLRSLIASILD
RSNQLAAAAEETSAITSQTTIGIQEQKSQVDQVATATTELSSSAHQVNMSADDALSQIKQADEETQHMRTIADENKRTIL
SLADEVAKASKVINKVHSDSASIGSILDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQDSTREIQ
QMIEVLQQGTQQAVAVMQLGQNQAQSCVEKTEQANQALQTISHSVHKAYDAGTHIAQAAQEQNLVSQQVSEKLEHIAAIS
EETALGAEQTAKSSHEVARLAEELQSSVKEFRV

Sequences:

>Translated_673_residues
MKIKVATRVIGGFSFVTLLLVILGGASLVTNNNLKDSTAIMQELSMPALEATGHLSETLSEQQRLILKAFHSKNSSTVPG
LERTFDQLSSGFNNQFTLLSGLLNNRDNFQGQLSGLSSSYQVLESNSKAMLKARFDSLSQQEELLKLREKLENSADDASS
NLFDLIDLESSQNQTEREIAAAAGAIDTTMTGIITTVYDLVAAEERSKYELISKELDYMLGEVKTKMEYISRHGEGIIDA
DLVSTLNDDSTKVLKMLEGKDTLVTLKSRQIDSTQLTSEKLTLVEKNALTVTEQMKRLAKDIETVTNDISNQALNDINSA
SLRTLILVVIAIVVAVVISFAVVRPLKRSLDEVNGALNVLASGDLTHKLDDTGHDEFAELSRNCNRLVDSLRSLIASILD
RSNQLAAAAEETSAITSQTTIGIQEQKSQVDQVATATTELSSSAHQVNMSADDALSQIKQADEETQHMRTIADENKRTIL
SLADEVAKASKVINKVHSDSASIGSILDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQDSTREIQ
QMIEVLQQGTQQAVAVMQLGQNQAQSCVEKTEQANQALQTISHSVHKAYDAGTHIAQAAQEQNLVSQQVSEKLEHIAAIS
EETALGAEQTAKSSHEVARLAEELQSSVKEFRV
>Mature_673_residues
MKIKVATRVIGGFSFVTLLLVILGGASLVTNNNLKDSTAIMQELSMPALEATGHLSETLSEQQRLILKAFHSKNSSTVPG
LERTFDQLSSGFNNQFTLLSGLLNNRDNFQGQLSGLSSSYQVLESNSKAMLKARFDSLSQQEELLKLREKLENSADDASS
NLFDLIDLESSQNQTEREIAAAAGAIDTTMTGIITTVYDLVAAEERSKYELISKELDYMLGEVKTKMEYISRHGEGIIDA
DLVSTLNDDSTKVLKMLEGKDTLVTLKSRQIDSTQLTSEKLTLVEKNALTVTEQMKRLAKDIETVTNDISNQALNDINSA
SLRTLILVVIAIVVAVVISFAVVRPLKRSLDEVNGALNVLASGDLTHKLDDTGHDEFAELSRNCNRLVDSLRSLIASILD
RSNQLAAAAEETSAITSQTTIGIQEQKSQVDQVATATTELSSSAHQVNMSADDALSQIKQADEETQHMRTIADENKRTIL
SLADEVAKASKVINKVHSDSASIGSILDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQDSTREIQ
QMIEVLQQGTQQAVAVMQLGQNQAQSCVEKTEQANQALQTISHSVHKAYDAGTHIAQAAQEQNLVSQQVSEKLEHIAAIS
EETALGAEQTAKSSHEVARLAEELQSSVKEFRV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=349, Percent_Identity=27.5071633237822, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1788194, Length=357, Percent_Identity=29.1316526610644, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1789453, Length=335, Percent_Identity=31.3432835820896, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI2367378, Length=283, Percent_Identity=32.1554770318021, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1788195, Length=228, Percent_Identity=34.2105263157895, Blast_Score=110, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 73051; Mature: 73051

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKVATRVIGGFSFVTLLLVILGGASLVTNNNLKDSTAIMQELSMPALEATGHLSETLS
CCEEHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
EQQRLILKAFHSKNSSTVPGLERTFDQLSSGFNNQFTLLSGLLNNRDNFQGQLSGLSSSY
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHCCHHHH
QVLESNSKAMLKARFDSLSQQEELLKLREKLENSADDASSNLFDLIDLESSQNQTEREIA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHCCCCCCCHHHHHHH
AAAGAIDTTMTGIITTVYDLVAAEERSKYELISKELDYMLGEVKTKMEYISRHGEGIIDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DLVSTLNDDSTKVLKMLEGKDTLVTLKSRQIDSTQLTSEKLTLVEKNALTVTEQMKRLAK
HHHHHCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHH
DIETVTNDISNQALNDINSASLRTLILVVIAIVVAVVISFAVVRPLKRSLDEVNGALNVL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGDLTHKLDDTGHDEFAELSRNCNRLVDSLRSLIASILDRSNQLAAAAEETSAITSQTT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
IGIQEQKSQVDQVATATTELSSSAHQVNMSADDALSQIKQADEETQHMRTIADENKRTIL
CCHHHHHHHHHHHHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SLADEVAKASKVINKVHSDSASIGSILDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEH
VADEVRSLASRTQDSTREIQQMIEVLQQGTQQAVAVMQLGQNQAQSCVEKTEQANQALQT
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ISHSVHKAYDAGTHIAQAAQEQNLVSQQVSEKLEHIAAISEETALGAEQTAKSSHEVARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AEELQSSVKEFRV
HHHHHHHHHHHCC
>Mature Secondary Structure
MKIKVATRVIGGFSFVTLLLVILGGASLVTNNNLKDSTAIMQELSMPALEATGHLSETLS
CCEEHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
EQQRLILKAFHSKNSSTVPGLERTFDQLSSGFNNQFTLLSGLLNNRDNFQGQLSGLSSSY
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHCCHHHH
QVLESNSKAMLKARFDSLSQQEELLKLREKLENSADDASSNLFDLIDLESSQNQTEREIA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHCCCCCCCHHHHHHH
AAAGAIDTTMTGIITTVYDLVAAEERSKYELISKELDYMLGEVKTKMEYISRHGEGIIDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DLVSTLNDDSTKVLKMLEGKDTLVTLKSRQIDSTQLTSEKLTLVEKNALTVTEQMKRLAK
HHHHHCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHH
DIETVTNDISNQALNDINSASLRTLILVVIAIVVAVVISFAVVRPLKRSLDEVNGALNVL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGDLTHKLDDTGHDEFAELSRNCNRLVDSLRSLIASILDRSNQLAAAAEETSAITSQTT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
IGIQEQKSQVDQVATATTELSSSAHQVNMSADDALSQIKQADEETQHMRTIADENKRTIL
CCHHHHHHHHHHHHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SLADEVAKASKVINKVHSDSASIGSILDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEH
VADEVRSLASRTQDSTREIQQMIEVLQQGTQQAVAVMQLGQNQAQSCVEKTEQANQALQT
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ISHSVHKAYDAGTHIAQAAQEQNLVSQQVSEKLEHIAAISEETALGAEQTAKSSHEVARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AEELQSSVKEFRV
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]