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The map label for this gene is apaH [H]

Identifier: 119775953

GI number: 119775953

Start: 3359811

End: 3360623

Strand: Direct

Name: apaH [H]

Synonym: Sama_2821

Alternate gene names: 119775953

Gene position: 3359811-3360623 (Clockwise)

Preceding gene: 119775952

Following gene: 119775954

Centisome position: 78.02

GC content: 54.74

Gene sequence:

>813_bases
ATGGCGCGATACTTTGTCGGCGACATCCAGGGCTGTTATGAAGAGCTGATGCGGCTGCTCCTGCGGGTAGACTTTCATCC
GTCGCGGGATGAACTCTGGGCCGTGGGCGATCTGGTTGCCAGGGGGCCCGAGTCCCACAAGGTGTTGGGCTTTTTCACCT
CATTGGGTGATGCCGCCAAAGCCGTGCTGGGTAATCATGATTTGCATCTGCTTGCCATACAGGCCGGGCTCAAACGTCCC
AAACCCAGCGACAAGCTTAAAAAGCTTTTGGAATCCAAACACCTGCCTGGGTTTATTCACTGGGTGCGCCATCAACCCCT
GATGCGGGAGCTTCCCGAACATAAGCTCATCATGACCCATGCCGGGGTGCCTCCCCAATGGGATTTGCCCACACTGCGGG
AAGAAGCAAGCGAAGTGAACAAGGTACTGATGAGCGACACTTACCTTGACCTGATAGGCAGCATGTACACCGAAGAGCCG
GAGAGTTGGGATCCCGATGCATCTGGATTTCTGAGGCACAGATACTGTATCGACGCCCTGACGCGGATGCGCTTTCTTTA
CCTCGACGGTCGCCTGGACTTTGCCTGCAAAAAGCCCCCCGCCGACTGCGAAGGCTTGGCCTTGAAGCCCTGGTTTGAAT
TCCCGTCTAAGTTGGATGATTTTACCCTGGTGTTCGGTCATTGGGCCGCCCTGATGGGAAAAACAGATAATCCCAGGCGT
ATAGCCTTGGACACCGGCTGCTGTTGGGGTGAAGACCTCACACTCTGGCACCTTGAAACCGGGGAAAAAATTACCCAAAA
GAAGTTAAAATAG

Upstream 100 bases:

>100_bases
AGGCCGCTACGGTATGGTCTGGGAAGATGGAAAACCGTTTCAGGCCGCCATTCCCACCTTCCGCCTGGCCGTGCCCGGCG
TACTGCATTAATTCTCCGCC

Downstream 100 bases:

>100_bases
GGTTAAACTAAAGCTCGAAGAGGCCGATACAAAAGGGCCGCGCGTCAAAGCTCCATACTGCTTTCTGATTCGGGAAAAAA
ACTAAAACATCGCCGGAGTG

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MARYFVGDIQGCYEELMRLLLRVDFHPSRDELWAVGDLVARGPESHKVLGFFTSLGDAAKAVLGNHDLHLLAIQAGLKRP
KPSDKLKKLLESKHLPGFIHWVRHQPLMRELPEHKLIMTHAGVPPQWDLPTLREEASEVNKVLMSDTYLDLIGSMYTEEP
ESWDPDASGFLRHRYCIDALTRMRFLYLDGRLDFACKKPPADCEGLALKPWFEFPSKLDDFTLVFGHWAALMGKTDNPRR
IALDTGCCWGEDLTLWHLETGEKITQKKLK

Sequences:

>Translated_270_residues
MARYFVGDIQGCYEELMRLLLRVDFHPSRDELWAVGDLVARGPESHKVLGFFTSLGDAAKAVLGNHDLHLLAIQAGLKRP
KPSDKLKKLLESKHLPGFIHWVRHQPLMRELPEHKLIMTHAGVPPQWDLPTLREEASEVNKVLMSDTYLDLIGSMYTEEP
ESWDPDASGFLRHRYCIDALTRMRFLYLDGRLDFACKKPPADCEGLALKPWFEFPSKLDDFTLVFGHWAALMGKTDNPRR
IALDTGCCWGEDLTLWHLETGEKITQKKLK
>Mature_269_residues
ARYFVGDIQGCYEELMRLLLRVDFHPSRDELWAVGDLVARGPESHKVLGFFTSLGDAAKAVLGNHDLHLLAIQAGLKRPK
PSDKLKKLLESKHLPGFIHWVRHQPLMRELPEHKLIMTHAGVPPQWDLPTLREEASEVNKVLMSDTYLDLIGSMYTEEPE
SWDPDASGFLRHRYCIDALTRMRFLYLDGRLDFACKKPPADCEGLALKPWFEFPSKLDDFTLVFGHWAALMGKTDNPRRI
ALDTGCCWGEDLTLWHLETGEKITQKKLK

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=267, Percent_Identity=47.1910112359551, Blast_Score=253, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 30933; Mature: 30802

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARYFVGDIQGCYEELMRLLLRVDFHPSRDELWAVGDLVARGPESHKVLGFFTSLGDAAK
CCCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AVLGNHDLHLLAIQAGLKRPKPSDKLKKLLESKHLPGFIHWVRHQPLMRELPEHKLIMTH
HHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCCEEEEEE
AGVPPQWDLPTLREEASEVNKVLMSDTYLDLIGSMYTEEPESWDPDASGFLRHRYCIDAL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
TRMRFLYLDGRLDFACKKPPADCEGLALKPWFEFPSKLDDFTLVFGHWAALMGKTDNPRR
HHHHEEEECCCCCEEECCCCCCCCCCEECHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCE
IALDTGCCWGEDLTLWHLETGEKITQKKLK
EEEECCCCCCCCCEEEEECCCCHHHHHHCC
>Mature Secondary Structure 
ARYFVGDIQGCYEELMRLLLRVDFHPSRDELWAVGDLVARGPESHKVLGFFTSLGDAAK
CCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AVLGNHDLHLLAIQAGLKRPKPSDKLKKLLESKHLPGFIHWVRHQPLMRELPEHKLIMTH
HHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCCEEEEEE
AGVPPQWDLPTLREEASEVNKVLMSDTYLDLIGSMYTEEPESWDPDASGFLRHRYCIDAL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
TRMRFLYLDGRLDFACKKPPADCEGLALKPWFEFPSKLDDFTLVFGHWAALMGKTDNPRR
HHHHEEEECCCCCEEECCCCCCCCCCEECHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCE
IALDTGCCWGEDLTLWHLETGEKITQKKLK
EEEECCCCCCCCCEEEEECCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]