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The map label for this gene is engD [H]

Identifier: 119775703

GI number: 119775703

Start: 3078197

End: 3079288

Strand: Reverse

Name: engD [H]

Synonym: Sama_2571

Alternate gene names: 119775703

Gene position: 3079288-3078197 (Counterclockwise)

Preceding gene: 119775704

Following gene: 119775699

Centisome position: 71.51

GC content: 53.66

Gene sequence:

>1092_bases
ATGGGTTTTAAATGTGGCATCGTTGGTCTGCCCAACGTTGGTAAATCAACGCTCTTCAACGCGCTGACCAAGGCCGGTAT
TGAAGCGGCAAACTTTCCGTTTTGTACCATCGAGCCAAACACCGGCGTAGTGCCAATGCCAGACCCACGTTTGGACGAAT
TGGCCGCCATTGTTAAGCCTGAGCGTGTTATCCCGACGTCCATGGAATTTGTGGACATCGCCGGTCTGGTTGCCGGTGCT
TCCAAGGGCGAGGGTCTGGGCAATAAGTTTTTGGCCAACATCCGCGAAACCGAAGCTATCGGCCATGTGGTGCGTTGCTT
CGAGAACGAAAACATTGTGCACGTGGCTAACCGCGTTGACCCGGCCGGTGACATAGAAGTGATCAACACCGAGTTGGCGC
TGGCAGATCTCGACAGCGTTGAGCGTGCTATTGTGCGTCAGCAAAAGCGTGCCAAAGGCGGCGACAAAGAAGCCAAGTTC
GAAGTCGATGTACTTGAAAAGCTGCGCCCTGTGCTGGATGAAGGCAAGATGCTGCGCTCGCTGGAACTGTCCAAGGAAGA
GCTGGCTGCGGTGGCTTATCTGAACCTGCTGACCCTGAAGCCAACCATGTATATCGCCAACGTGTCTGAAGACGGCTTTG
AGAACAATCCGCATCTGGACGCCGTACGCGCCATTGCCGCCAAAGAAAATGCCGTGGTAGTGCCTGTATGTGCCGCCATT
GAATCTGAACTGGCGGAGATGGATATCGAAGAGCGCGATGAGTTCATGGCAGATCTCGGTCTAACCGAACCAGGCCTTGA
TCGCGTGATCCGCGCCGGTTATGAGCTGTTGAACCTGCAAACCTATTTCACCGCCGGTGTGAAAGAAGTGCGTGCCTGGA
CCGTGTCTGTTGGCGCCAGCGCGCCTCAGGCTGCCGGTAAAATTCATACCGACTTTGAGCGCGGATTTATCCGTGCCCAG
GTAATCTCCTACGAAGATTTTATTAACTTCAAGGGTGAGCAGGGCGCCAAAGAAGCTGGCAAGATGCGTGTGGAAGGTAA
AACTTACATCGTTAAAGATGGCGATGTGATGCACTTCCTGTTCAACGTCTAA

Upstream 100 bases:

>100_bases
ATCCTGTTCAAGCAAGACATGACCAAGGCAATGCACAGATTGCATTCCTTCAAGGCCGAATAATCAGTTAAGCAAGTAAG
TCAAATAAAGGGTTATAGCT

Downstream 100 bases:

>100_bases
GCCATTGGTCGGGCGGGAAACAGGCTTTTTTGCTTATCTGTTACCCGCTTTGATGAAGGATTAGGCGAACGGTATCTTTG
GGGCGAAATGTGCTAAAAAA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPMPDPRLDELAAIVKPERVIPTSMEFVDIAGLVAGA
SKGEGLGNKFLANIRETEAIGHVVRCFENENIVHVANRVDPAGDIEVINTELALADLDSVERAIVRQQKRAKGGDKEAKF
EVDVLEKLRPVLDEGKMLRSLELSKEELAAVAYLNLLTLKPTMYIANVSEDGFENNPHLDAVRAIAAKENAVVVPVCAAI
ESELAEMDIEERDEFMADLGLTEPGLDRVIRAGYELLNLQTYFTAGVKEVRAWTVSVGASAPQAAGKIHTDFERGFIRAQ
VISYEDFINFKGEQGAKEAGKMRVEGKTYIVKDGDVMHFLFNV

Sequences:

>Translated_363_residues
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPMPDPRLDELAAIVKPERVIPTSMEFVDIAGLVAGA
SKGEGLGNKFLANIRETEAIGHVVRCFENENIVHVANRVDPAGDIEVINTELALADLDSVERAIVRQQKRAKGGDKEAKF
EVDVLEKLRPVLDEGKMLRSLELSKEELAAVAYLNLLTLKPTMYIANVSEDGFENNPHLDAVRAIAAKENAVVVPVCAAI
ESELAEMDIEERDEFMADLGLTEPGLDRVIRAGYELLNLQTYFTAGVKEVRAWTVSVGASAPQAAGKIHTDFERGFIRAQ
VISYEDFINFKGEQGAKEAGKMRVEGKTYIVKDGDVMHFLFNV
>Mature_362_residues
GFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPMPDPRLDELAAIVKPERVIPTSMEFVDIAGLVAGAS
KGEGLGNKFLANIRETEAIGHVVRCFENENIVHVANRVDPAGDIEVINTELALADLDSVERAIVRQQKRAKGGDKEAKFE
VDVLEKLRPVLDEGKMLRSLELSKEELAAVAYLNLLTLKPTMYIANVSEDGFENNPHLDAVRAIAAKENAVVVPVCAAIE
SELAEMDIEERDEFMADLGLTEPGLDRVIRAGYELLNLQTYFTAGVKEVRAWTVSVGASAPQAAGKIHTDFERGFIRAQV
ISYEDFINFKGEQGAKEAGKMRVEGKTYIVKDGDVMHFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=45.3804347826087, Blast_Score=310, Evalue=1e-84,
Organism=Homo sapiens, GI58761502, Length=233, Percent_Identity=40.343347639485, Blast_Score=168, Evalue=8e-42,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=81.267217630854, Blast_Score=615, Evalue=1e-177,
Organism=Escherichia coli, GI1789574, Length=127, Percent_Identity=29.9212598425197, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17509631, Length=365, Percent_Identity=41.9178082191781, Blast_Score=298, Evalue=4e-81,
Organism=Saccharomyces cerevisiae, GI6319499, Length=368, Percent_Identity=39.4021739130435, Blast_Score=261, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=35.8839050131926, Blast_Score=201, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6321649, Length=162, Percent_Identity=38.2716049382716, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640873, Length=366, Percent_Identity=42.896174863388, Blast_Score=300, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24640877, Length=366, Percent_Identity=42.896174863388, Blast_Score=300, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24640875, Length=366, Percent_Identity=42.896174863388, Blast_Score=300, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24640879, Length=328, Percent_Identity=40.5487804878049, Blast_Score=245, Evalue=4e-65,
Organism=Drosophila melanogaster, GI24585318, Length=196, Percent_Identity=30.1020408163265, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39564; Mature: 39433

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPMPDPRLDELAAIVKP
CCEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHCC
ERVIPTSMEFVDIAGLVAGASKGEGLGNKFLANIRETEAIGHVVRCFENENIVHVANRVD
CCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PAGDIEVINTELALADLDSVERAIVRQQKRAKGGDKEAKFEVDVLEKLRPVLDEGKMLRS
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
LELSKEELAAVAYLNLLTLKPTMYIANVSEDGFENNPHLDAVRAIAAKENAVVVPVCAAI
HHCCHHHHHHHHHHHHHEECCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEHHHHH
ESELAEMDIEERDEFMADLGLTEPGLDRVIRAGYELLNLQTYFTAGVKEVRAWTVSVGAS
HHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCC
APQAAGKIHTDFERGFIRAQVISYEDFINFKGEQGAKEAGKMRVEGKTYIVKDGDVMHFL
CCHHCCCCCCHHHHCEEEEEEECHHHHHCCCCCCCCHHHCCEEECCCEEEEECCCEEEEE
FNV
ECC
>Mature Secondary Structure 
GFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPMPDPRLDELAAIVKP
CEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHCC
ERVIPTSMEFVDIAGLVAGASKGEGLGNKFLANIRETEAIGHVVRCFENENIVHVANRVD
CCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PAGDIEVINTELALADLDSVERAIVRQQKRAKGGDKEAKFEVDVLEKLRPVLDEGKMLRS
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
LELSKEELAAVAYLNLLTLKPTMYIANVSEDGFENNPHLDAVRAIAAKENAVVVPVCAAI
HHCCHHHHHHHHHHHHHEECCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEHHHHH
ESELAEMDIEERDEFMADLGLTEPGLDRVIRAGYELLNLQTYFTAGVKEVRAWTVSVGAS
HHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCC
APQAAGKIHTDFERGFIRAQVISYEDFINFKGEQGAKEAGKMRVEGKTYIVKDGDVMHFL
CCHHCCCCCCHHHHCEEEEEEECHHHHHCCCCCCCCHHHCCEEECCCEEEEECCCEEEEE
FNV
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]