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The map label for this gene is nahR [H]

Identifier: 119775652

GI number: 119775652

Start: 3028542

End: 3029450

Strand: Reverse

Name: nahR [H]

Synonym: Sama_2520

Alternate gene names: 119775652

Gene position: 3029450-3028542 (Counterclockwise)

Preceding gene: 119775658

Following gene: 119775650

Centisome position: 70.35

GC content: 59.3

Gene sequence:

>909_bases
ATGAAACTGCATCAACTCGACCTGAATCTGCTGCTTGCCTTTGACGCCCTGATGACCCAGGGCAGCGTGACCCGCGCGGC
CGAGTCGCTGTTTATCAGCCAGCCGGCAATGAGTCATGCTCTGGGCAGACTGCGCACCGCCTTTGGCGATCAGCTGTTGG
TGCGCACTCCGCAGGGGATGGTGCCCACGCCCCGGGCCCAGCATCTGCACAGTGGTGTGCGTCAGGCGCTGCGGCTTTTG
GAGCAGCAGCTCAGCGAAGAAGAAGCCTTCGAGCCCGAAAACTCGCGGCGCCGCTTTGTGCTGTGTACCACCGACTATGT
GGAGTGCGTGCTGATGCCGCCTTTGGTGCAGCGCCTCAATGAACTCGCCCCCGGGGTCAGCATTGAGATCCGTATTCTCA
GAGATAGGCTGCCGGAGGCGGAGCTGGCCTCCGGCGAAATCGATTTGGTGCTGGGCTTTGATGAGTACATGCAGGTACCG
GCCTATCTTGGCAAAGAAACCTGGCTTACCGAGCCGCTGGCAGGTTTGGTGCGAAAGGACTTACCCGGGGTTGGTGAGCG
GATGGCGCTTAGCGAACTTATCGGCATGGCCCATGTGTTTCATTCACCCCTTGGCACTTCAGAGGCGCGGCTCGATAACT
GGCTTGAAAGCCAGGGCTTGTCGCGGCGTATTTCGGTGAACAGCCAAAGCTATATGTCGGCGGCGGCCATTGTGTGTCGA
AGCGACTATGTATTGGTGCTGCCCAAAAAGGTGGCAGATTTGCTGGCCGAACACTGGCCGCTGAAGCGGCTTCAACTACC
TGAGGATGTGCCCGGTTATCACCTGAACTGCGTCTGGCACCCGGCGCTTGGTGGGCATCCGGCGCTGATTTGGCTTCGCA
GTTTGATGAAAGAGTTGGTGAGTGGCTAG

Upstream 100 bases:

>100_bases
CCTTTTTGGCGATGATTGAGTAGAGACAGTGTAAGAAGTTGCGCATCCATACAACAAATGAATAAGATGTATGTGCCCAT
AAATATCGCGAATAGTGGTC

Downstream 100 bases:

>100_bases
GCCATATAGCCCCAACGCTTTGCAGATAGATAAAGAAAAGGGCGACTGAAGTGTCGCCCTTTTAACTGGATTTATTTACG
GCTCAGGCCTTTTCAGGAAT

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MKLHQLDLNLLLAFDALMTQGSVTRAAESLFISQPAMSHALGRLRTAFGDQLLVRTPQGMVPTPRAQHLHSGVRQALRLL
EQQLSEEEAFEPENSRRRFVLCTTDYVECVLMPPLVQRLNELAPGVSIEIRILRDRLPEAELASGEIDLVLGFDEYMQVP
AYLGKETWLTEPLAGLVRKDLPGVGERMALSELIGMAHVFHSPLGTSEARLDNWLESQGLSRRISVNSQSYMSAAAIVCR
SDYVLVLPKKVADLLAEHWPLKRLQLPEDVPGYHLNCVWHPALGGHPALIWLRSLMKELVSG

Sequences:

>Translated_302_residues
MKLHQLDLNLLLAFDALMTQGSVTRAAESLFISQPAMSHALGRLRTAFGDQLLVRTPQGMVPTPRAQHLHSGVRQALRLL
EQQLSEEEAFEPENSRRRFVLCTTDYVECVLMPPLVQRLNELAPGVSIEIRILRDRLPEAELASGEIDLVLGFDEYMQVP
AYLGKETWLTEPLAGLVRKDLPGVGERMALSELIGMAHVFHSPLGTSEARLDNWLESQGLSRRISVNSQSYMSAAAIVCR
SDYVLVLPKKVADLLAEHWPLKRLQLPEDVPGYHLNCVWHPALGGHPALIWLRSLMKELVSG
>Mature_302_residues
MKLHQLDLNLLLAFDALMTQGSVTRAAESLFISQPAMSHALGRLRTAFGDQLLVRTPQGMVPTPRAQHLHSGVRQALRLL
EQQLSEEEAFEPENSRRRFVLCTTDYVECVLMPPLVQRLNELAPGVSIEIRILRDRLPEAELASGEIDLVLGFDEYMQVP
AYLGKETWLTEPLAGLVRKDLPGVGERMALSELIGMAHVFHSPLGTSEARLDNWLESQGLSRRISVNSQSYMSAAAIVCR
SDYVLVLPKKVADLLAEHWPLKRLQLPEDVPGYHLNCVWHPALGGHPALIWLRSLMKELVSG

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=300, Percent_Identity=28.3333333333333, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI87081766, Length=265, Percent_Identity=24.9056603773585, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1786820, Length=294, Percent_Identity=25.1700680272109, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=254, Percent_Identity=22.8346456692913, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790147, Length=307, Percent_Identity=21.8241042345277, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33734; Mature: 33734

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHQLDLNLLLAFDALMTQGSVTRAAESLFISQPAMSHALGRLRTAFGDQLLVRTPQGM
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCC
VPTPRAQHLHSGVRQALRLLEQQLSEEEAFEPENSRRRFVLCTTDYVECVLMPPLVQRLN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHCCHHHHHHH
ELAPGVSIEIRILRDRLPEAELASGEIDLVLGFDEYMQVPAYLGKETWLTEPLAGLVRKD
HHCCCCEEEEEEEHHHCCCCHHCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHC
LPGVGERMALSELIGMAHVFHSPLGTSEARLDNWLESQGLSRRISVNSQSYMSAAAIVCR
CCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHC
SDYVLVLPKKVADLLAEHWPLKRLQLPEDVPGYHLNCVWHPALGGHPALIWLRSLMKELV
CCCEEEECHHHHHHHHHHCCCHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
SG
CC
>Mature Secondary Structure
MKLHQLDLNLLLAFDALMTQGSVTRAAESLFISQPAMSHALGRLRTAFGDQLLVRTPQGM
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCC
VPTPRAQHLHSGVRQALRLLEQQLSEEEAFEPENSRRRFVLCTTDYVECVLMPPLVQRLN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHCCHHHHHHH
ELAPGVSIEIRILRDRLPEAELASGEIDLVLGFDEYMQVPAYLGKETWLTEPLAGLVRKD
HHCCCCEEEEEEEHHHCCCCHHCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHC
LPGVGERMALSELIGMAHVFHSPLGTSEARLDNWLESQGLSRRISVNSQSYMSAAAIVCR
CCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHC
SDYVLVLPKKVADLLAEHWPLKRLQLPEDVPGYHLNCVWHPALGGHPALIWLRSLMKELV
CCCEEEECHHHHHHHHHHCCCHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
SG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]