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The map label for this gene is purP [H]

Identifier: 119775649

GI number: 119775649

Start: 3023065

End: 3024354

Strand: Reverse

Name: purP [H]

Synonym: Sama_2517

Alternate gene names: 119775649

Gene position: 3024354-3023065 (Counterclockwise)

Preceding gene: 119775650

Following gene: 119775648

Centisome position: 70.23

GC content: 55.66

Gene sequence:

>1290_bases
ATGTTAGAAAAACTCTTTAAACTCAAAGAAAACCAAACGACCTTAAAGCAGGAAGTGGTTGCGGGGTTAACAACCTTCCT
GACCATGGCGTACATTATTTTCGTCAATCCCATGATGCTGGCCGACGCCGGTATGGATCATGGCGCCGTGTTTGTGGCGA
CCTGTCTTGCGGCGGCCGTAGGTTGTTTGATCATGGGCCTGATGGCCAACTATCCCATCGCTCTGGCACCCGGTATGGGG
CTTAACGCCTTCTTCACCTACACAGTGGTGGGTGAAATGGGTTACAGCTGGGAAACTGCGCTCGGCGCCGTATTTATGTC
CGGTGTCTGCTTCCTGATATTGTCGCTGGTGCGTATTCGCGAGTGGATTGTGAACTCCATTCCCATGTCGCTGCGTCTTG
GCATTGCTGCCGGTATTGGTCTGTTCCTGGCGCTGATTGGTCTTAAGAGCGCGGGTATCGTGGTGGCAAGCCCTGCGACC
CTCGTAACCATGGGCGATATCAAGGCCTTCCCTGCTGTGATGGCGGTTCTGGGCTTTTTCCTGATTATTGCCATGGTAAA
TCGCGGCATGAAGTCAGCGGTAATCTTAAGCATTCTGGCCATCACAGGCCTGGGGCTGCTCTTTGGTGATGTGCAGTACC
ACGGTCTGGTGTCGGCGCCCCCCTCCATTGCCCCTACCTTTATGAAGATGGACCTCTCGGCCGTACTGGAAGTGAGCATG
CTGTCTGTGGTATTCGCCTTCCTGTTTGTGGATCTCTTCGACACATCAGGCACCCTGGTCGCCGTAGCCCAGCGCGGTGG
ATTCCTCGATGACAAAGGCCGTCTGCCACGCCTGAACCGTGCTCTGACCGCCGACAGTGTGGCCACCATTGCCGGTGCCA
GCCTGGGTACCTCAACCACAACCAGTTATATCGAGAGTACAGCCGGTGTGAGTGCCGGTGGCCGTACCGGTCTGACTGCC
GTGGTGGTAGGGCTGCTGTTTTTGGCGTCACTCTTTATTTCACCGCTGGCGGGCATGGTGCCGGCCTACGCTACCGCAGG
CACCCTGTTCTATGTGGCGATTCTGATGATGTCAGGTCTGGTGCACGTAGAGTGGGAAGACATCACTGAAGCTGCCCCTG
TGGTGGTAGTGTGTCTCTTGATGCCGCTGACCTTCTCCATTGCTTCGGGTATCGCCTTTGGTTTTATTTCTTACGCCGCC
ATCAAGGCACTGAGTGGCCGTTTCCGCGACCTCAACGTGGGTATTGTGGTGCTGGCACTGCTGTTTGTCGCGAAGTTTGC
CTTTGCCTGA

Upstream 100 bases:

>100_bases
GGAAAGCCCCTATAATCTGCGCCGAATCGAGAATGTTAACGCATTTTTACATTCACCCTCTCGTACCCAATACTAAAACA
AGATCAAGGAACCCAGTTCC

Downstream 100 bases:

>100_bases
TAGCCCCCGGGCTGCTTAACAGATTAAGGGTCATACAATGTATGGCCCTTTTTTTGTGCATTTTTTCAACATGAGTGCTT
TTTGTGGCAAATATCCATCG

Product: xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MLEKLFKLKENQTTLKQEVVAGLTTFLTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAVGCLIMGLMANYPIALAPGMG
LNAFFTYTVVGEMGYSWETALGAVFMSGVCFLILSLVRIREWIVNSIPMSLRLGIAAGIGLFLALIGLKSAGIVVASPAT
LVTMGDIKAFPAVMAVLGFFLIIAMVNRGMKSAVILSILAITGLGLLFGDVQYHGLVSAPPSIAPTFMKMDLSAVLEVSM
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDDKGRLPRLNRALTADSVATIAGASLGTSTTTSYIESTAGVSAGGRTGLTA
VVVGLLFLASLFISPLAGMVPAYATAGTLFYVAILMMSGLVHVEWEDITEAAPVVVVCLLMPLTFSIASGIAFGFISYAA
IKALSGRFRDLNVGIVVLALLFVAKFAFA

Sequences:

>Translated_429_residues
MLEKLFKLKENQTTLKQEVVAGLTTFLTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAVGCLIMGLMANYPIALAPGMG
LNAFFTYTVVGEMGYSWETALGAVFMSGVCFLILSLVRIREWIVNSIPMSLRLGIAAGIGLFLALIGLKSAGIVVASPAT
LVTMGDIKAFPAVMAVLGFFLIIAMVNRGMKSAVILSILAITGLGLLFGDVQYHGLVSAPPSIAPTFMKMDLSAVLEVSM
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDDKGRLPRLNRALTADSVATIAGASLGTSTTTSYIESTAGVSAGGRTGLTA
VVVGLLFLASLFISPLAGMVPAYATAGTLFYVAILMMSGLVHVEWEDITEAAPVVVVCLLMPLTFSIASGIAFGFISYAA
IKALSGRFRDLNVGIVVLALLFVAKFAFA
>Mature_429_residues
MLEKLFKLKENQTTLKQEVVAGLTTFLTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAVGCLIMGLMANYPIALAPGMG
LNAFFTYTVVGEMGYSWETALGAVFMSGVCFLILSLVRIREWIVNSIPMSLRLGIAAGIGLFLALIGLKSAGIVVASPAT
LVTMGDIKAFPAVMAVLGFFLIIAMVNRGMKSAVILSILAITGLGLLFGDVQYHGLVSAPPSIAPTFMKMDLSAVLEVSM
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDDKGRLPRLNRALTADSVATIAGASLGTSTTTSYIESTAGVSAGGRTGLTA
VVVGLLFLASLFISPLAGMVPAYATAGTLFYVAILMMSGLVHVEWEDITEAAPVVVVCLLMPLTFSIASGIAFGFISYAA
IKALSGRFRDLNVGIVVLALLFVAKFAFA

Specific function: High-affinity uptake of adenine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=428, Percent_Identity=51.6355140186916, Blast_Score=456, Evalue=1e-130,
Organism=Escherichia coli, GI87082309, Length=424, Percent_Identity=50.7075471698113, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI1790499, Length=434, Percent_Identity=39.4009216589862, Blast_Score=282, Evalue=3e-77,
Organism=Escherichia coli, GI48994909, Length=433, Percent_Identity=39.0300230946882, Blast_Score=267, Evalue=8e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 44888; Mature: 44888

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKLFKLKENQTTLKQEVVAGLTTFLTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAV
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GCLIMGLMANYPIALAPGMGLNAFFTYTVVGEMGYSWETALGAVFMSGVCFLILSLVRIR
HHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EWIVNSIPMSLRLGIAAGIGLFLALIGLKSAGIVVASPATLVTMGDIKAFPAVMAVLGFF
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECHHHHHHHHHHHHHHH
LIIAMVNRGMKSAVILSILAITGLGLLFGDVQYHGLVSAPPSIAPTFMKMDLSAVLEVSM
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDDKGRLPRLNRALTADSVATIAGASLGTSTT
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHH
TSYIESTAGVSAGGRTGLTAVVVGLLFLASLFISPLAGMVPAYATAGTLFYVAILMMSGL
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VHVEWEDITEAAPVVVVCLLMPLTFSIASGIAFGFISYAAIKALSGRFRDLNVGIVVLAL
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LFVAKFAFA
HHHHHHHCC
>Mature Secondary Structure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HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]