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The map label for this gene is ifcA [H]

Identifier: 119775535

GI number: 119775535

Start: 2884839

End: 2886356

Strand: Direct

Name: ifcA [H]

Synonym: Sama_2401

Alternate gene names: 119775535

Gene position: 2884839-2886356 (Clockwise)

Preceding gene: 119775531

Following gene: 119775536

Centisome position: 66.99

GC content: 56.46

Gene sequence:

>1518_bases
ATGAACGAGAAAATCAAACAAAGCCGCCGCGCCTTCCTCAAGGGAGGTCTGGCACTGTCAGCCGTTGGGCTGGCCCCCGC
CGTGCTGGCCAAGTCCAGCGAAGATAACGCCATTCAGTGGGATGAAACCTTTGACGTTGTCGTGGTAGGCAGCGGTTTGG
CGGGCACCTGCGCCGCCATCCGGGCAAAGGAAAATGGCGCCAAAAACACCATTATTATTGAAAAAATGCCGGTACTGGGC
GGAACGTCTGCCATCTCAGGTCTGAACTTCTCCGTGGTCAACAGTCACCTGCAACAGGCACAGGGGATTGAAGATTCTGC
CGCACTTTTCGCCGAGGACATCTCCAGGGCGGGCGGCTATCAGAACCACAGAGCGCTGACCCTGAAAATGGCCGATACCA
CCACCCGGGTATTGCCCTGGGCAATCGAGCGGGGTTGCCGTTTCCATGACAAGTTAAAGAGCCTCGGCGGTCATTCGGTG
CCACGGACACTTTATCCTGTCAATGGCGGTGGCAAAGGCATACTGCGCCCGCTGCGTCGCTTCTATACCCAGGACTTACA
GGGCGACATCCGCCGCAGAGTCAAGTTTGACAAGCTGCATCTGAATGCCCGGGGCGAGGTCATGGGGATTCAGGTACGCG
AACAGTACTTTTTTGACCCAAATCTGGGGAATGACGACCGGGAAAACACCACTGGCACCATCAAACATTATCGGGTGACC
AAGGGTGTGGTCATGGCCGTGGGCGGCTACAGCCGCGATGTGGAGTTCCGTGCCATGGAGTTTCCCAATATTCGCGATTA
CATCCCAACCACCACTCACAGGGGCGCAACCGCCGGTGCACTCAAGTCTCTGGTTGCAGCCGGTGCACAGACAGTCCATC
TGTCTTTGATGCGCTTTGCCTTTGATATCCCTACCGAAGATTTGCAGTGGGGTGCCTTGGTCGACCCCAAAACGGGTCAG
CGCTTTATCAGCGAAAAGAACAACCGCCAGGTCGTGGCAGAAGCCATCTGCAACATCATGGACCGCAACGAGGGTCGCTT
CCCGCTGAATATTTACGATCAGGATGGCATCGACAACTTCCACGACAAACAGCGCCTGCACCTCGCTTTGGAGGAAGGCA
TGATGGTGAAGTACGACTCCATCGAGGCCCTGGCCAACGGGGAAGGCATCGATCTTACCGGGCTTGCGGCCACACTCAAG
CGCTATAACGAGGATGCCCTGTCAGGCAAAGACAGCCAGTTCGGTAAAGACATGGCCGCGTTGAAACAAGTGAGTGTCAA
ACGAGCGCCTTTCTATGCCATCAAGGCCCGTCCGAAATTCAACTACACCCAGGGCGGCGTATTAATCAATGAAAATGCCC
AGGTCATCAACAGGGACACAGCCCAACCCATCAAAGGCCTTTATGCCTGCGGCGAAGCCACGGGCGGGCTGTTCGGCCGA
ATTCGATTAACTGCCTGCTCCTGCCCCGATGCGTTCGCATTTGGGGTGATTGCCGGTGAACAGGTGGCCAAGGCCTGA

Upstream 100 bases:

>100_bases
TTGATCCGCTTCACAGCCTGATATGCGCTTCGGAAAACCACTATATAGCCGCTGCCCGCTTTTTGATTCCATGGCCCTGT
CATCATGAAGTGAGGCCACT

Downstream 100 bases:

>100_bases
GGAGACACACATGAAAACCCTGATTTTATCCCTGCTGGCACTGAGTTTTGTCGCATCCCCCTTACACGCAGGGGAGCTCT
ACAAGGTAATGGGCAAGCGT

Product: flavocytochrome c flavin subunit

Products: NA

Alternate protein names: Fe(3+)-induced flavocytochrome C3; Ifc3; Iron(III)-induced flavocytochrome C3 [H]

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MNEKIKQSRRAFLKGGLALSAVGLAPAVLAKSSEDNAIQWDETFDVVVVGSGLAGTCAAIRAKENGAKNTIIIEKMPVLG
GTSAISGLNFSVVNSHLQQAQGIEDSAALFAEDISRAGGYQNHRALTLKMADTTTRVLPWAIERGCRFHDKLKSLGGHSV
PRTLYPVNGGGKGILRPLRRFYTQDLQGDIRRRVKFDKLHLNARGEVMGIQVREQYFFDPNLGNDDRENTTGTIKHYRVT
KGVVMAVGGYSRDVEFRAMEFPNIRDYIPTTTHRGATAGALKSLVAAGAQTVHLSLMRFAFDIPTEDLQWGALVDPKTGQ
RFISEKNNRQVVAEAICNIMDRNEGRFPLNIYDQDGIDNFHDKQRLHLALEEGMMVKYDSIEALANGEGIDLTGLAATLK
RYNEDALSGKDSQFGKDMAALKQVSVKRAPFYAIKARPKFNYTQGGVLINENAQVINRDTAQPIKGLYACGEATGGLFGR
IRLTACSCPDAFAFGVIAGEQVAKA

Sequences:

>Translated_505_residues
MNEKIKQSRRAFLKGGLALSAVGLAPAVLAKSSEDNAIQWDETFDVVVVGSGLAGTCAAIRAKENGAKNTIIIEKMPVLG
GTSAISGLNFSVVNSHLQQAQGIEDSAALFAEDISRAGGYQNHRALTLKMADTTTRVLPWAIERGCRFHDKLKSLGGHSV
PRTLYPVNGGGKGILRPLRRFYTQDLQGDIRRRVKFDKLHLNARGEVMGIQVREQYFFDPNLGNDDRENTTGTIKHYRVT
KGVVMAVGGYSRDVEFRAMEFPNIRDYIPTTTHRGATAGALKSLVAAGAQTVHLSLMRFAFDIPTEDLQWGALVDPKTGQ
RFISEKNNRQVVAEAICNIMDRNEGRFPLNIYDQDGIDNFHDKQRLHLALEEGMMVKYDSIEALANGEGIDLTGLAATLK
RYNEDALSGKDSQFGKDMAALKQVSVKRAPFYAIKARPKFNYTQGGVLINENAQVINRDTAQPIKGLYACGEATGGLFGR
IRLTACSCPDAFAFGVIAGEQVAKA
>Mature_505_residues
MNEKIKQSRRAFLKGGLALSAVGLAPAVLAKSSEDNAIQWDETFDVVVVGSGLAGTCAAIRAKENGAKNTIIIEKMPVLG
GTSAISGLNFSVVNSHLQQAQGIEDSAALFAEDISRAGGYQNHRALTLKMADTTTRVLPWAIERGCRFHDKLKSLGGHSV
PRTLYPVNGGGKGILRPLRRFYTQDLQGDIRRRVKFDKLHLNARGEVMGIQVREQYFFDPNLGNDDRENTTGTIKHYRVT
KGVVMAVGGYSRDVEFRAMEFPNIRDYIPTTTHRGATAGALKSLVAAGAQTVHLSLMRFAFDIPTEDLQWGALVDPKTGQ
RFISEKNNRQVVAEAICNIMDRNEGRFPLNIYDQDGIDNFHDKQRLHLALEEGMMVKYDSIEALANGEGIDLTGLAATLK
RYNEDALSGKDSQFGKDMAALKQVSVKRAPFYAIKARPKFNYTQGGVLINENAQVINRDTAQPIKGLYACGEATGGLFGR
IRLTACSCPDAFAFGVIAGEQVAKA

Specific function: Catalyzes unidirectional fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71986328, Length=477, Percent_Identity=25.7861635220126, Blast_Score=109, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6322511, Length=491, Percent_Identity=25.6619144602851, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6320788, Length=486, Percent_Identity=26.1316872427983, Blast_Score=106, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR010960
- InterPro:   IPR011031 [H]

Pfam domain/function: PF00890 FAD_binding_2 [H]

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 55187; Mature: 55187

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEKIKQSRRAFLKGGLALSAVGLAPAVLAKSSEDNAIQWDETFDVVVVGSGLAGTCAAI
CCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCCEEECCCEEEEEECCCCCCHHHHE
RAKENGAKNTIIIEKMPVLGGTSAISGLNFSVVNSHLQQAQGIEDSAALFAEDISRAGGY
EECCCCCCCEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
QNHRALTLKMADTTTRVLPWAIERGCRFHDKLKSLGGHSVPRTLYPVNGGGKGILRPLRR
CCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHH
FYTQDLQGDIRRRVKFDKLHLNARGEVMGIQVREQYFFDPNLGNDDRENTTGTIKHYRVT
HHHHHHHHHHHHHEEEEEEEECCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEE
KGVVMAVGGYSRDVEFRAMEFPNIRDYIPTTTHRGATAGALKSLVAAGAQTVHLSLMRFA
CCEEEEECCCCCCCEEEEECCCCCHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
FDIPTEDLQWGALVDPKTGQRFISEKNNRQVVAEAICNIMDRNEGRFPLNIYDQDGIDNF
HCCCCCCCCCCEEECCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
HDKQRLHLALEEGMMVKYDSIEALANGEGIDLTGLAATLKRYNEDALSGKDSQFGKDMAA
CCHHHHEEEECCCEEEEECCHHHHCCCCCCCHHHHHHHHHHHCHHHCCCCCHHHHHHHHH
LKQVSVKRAPFYAIKARPKFNYTQGGVLINENAQVINRDTAQPIKGLYACGEATGGLFGR
HHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCCEECCCCHHHHHHHHHHCCCCCCEEEE
IRLTACSCPDAFAFGVIAGEQVAKA
EEEEEECCCCHHHHHHCCCHHHHCC
>Mature Secondary Structure
MNEKIKQSRRAFLKGGLALSAVGLAPAVLAKSSEDNAIQWDETFDVVVVGSGLAGTCAAI
CCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCCEEECCCEEEEEECCCCCCHHHHE
RAKENGAKNTIIIEKMPVLGGTSAISGLNFSVVNSHLQQAQGIEDSAALFAEDISRAGGY
EECCCCCCCEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
QNHRALTLKMADTTTRVLPWAIERGCRFHDKLKSLGGHSVPRTLYPVNGGGKGILRPLRR
CCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHH
FYTQDLQGDIRRRVKFDKLHLNARGEVMGIQVREQYFFDPNLGNDDRENTTGTIKHYRVT
HHHHHHHHHHHHHEEEEEEEECCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEE
KGVVMAVGGYSRDVEFRAMEFPNIRDYIPTTTHRGATAGALKSLVAAGAQTVHLSLMRFA
CCEEEEECCCCCCCEEEEECCCCCHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
FDIPTEDLQWGALVDPKTGQRFISEKNNRQVVAEAICNIMDRNEGRFPLNIYDQDGIDNF
HCCCCCCCCCCEEECCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
HDKQRLHLALEEGMMVKYDSIEALANGEGIDLTGLAATLKRYNEDALSGKDSQFGKDMAA
CCHHHHEEEECCCEEEEECCHHHHCCCCCCCHHHHHHHHHHHCHHHCCCCCHHHHHHHHH
LKQVSVKRAPFYAIKARPKFNYTQGGVLINENAQVINRDTAQPIKGLYACGEATGGLFGR
HHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCCEECCCCHHHHHHHHHHCCCCCCEEEE
IRLTACSCPDAFAFGVIAGEQVAKA
EEEEEECCCCHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10455032; 10581549 [H]