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The map label for this gene is hlyB [H]

Identifier: 119775531

GI number: 119775531

Start: 2880177

End: 2881769

Strand: Direct

Name: hlyB [H]

Synonym: Sama_2397

Alternate gene names: 119775531

Gene position: 2880177-2881769 (Clockwise)

Preceding gene: 119775530

Following gene: 119775535

Centisome position: 66.89

GC content: 53.17

Gene sequence:

>1593_bases
ATGGCGCACCTGAATTCTGCCTCAATGGCAGCGCCTGTTTTCACAGCACGACTTACTTGCCCACTCAAATGGAGAGTCTC
AACAAAAATGAATAACCTAAGCTCTGAGATGATGCGGGATCATTACATTAAATCAGACACTATCATGTTTTCGGTGCTGG
TAATGATGTTCCTCTACGCCCTCGGTTTGGCGGGGGTTTTCGGTAACTGGACGGTGGCCATCATAGTCGGCTTACTGACC
ACAATAGCGGCGGGCGCAATCCGGGCCCTGAGCCCGGGAGAGCGTATTACCCGGGTGACCATGGGGCTGGCATTTATGGT
GATGGTCACCCTGCATGTGCACCTGTCCCGCGGCATGATAGAGATGCATTTTGGGTATTTTGCCTGTCTCGCGATGCTGC
TCTACTGCCGGGACTGGCTGCCCATCCTCGCTTCTGCGTTGCTTGCGGCGGTACTGCACGTGGGACTCTTCTGGTGGCAA
ACCACAGGTGGCAGTGTCTTTATGCTCGACAGTGCAGAACGCTCCTGGGGGATCATCTTCATCCACGCCGGTTATGTGGT
CGTTGAAACACTGGTGTTGGTGGTTATGGCCAAAAATTTGCACCGTCAGGCAGAGGTTTCTTTTGACATCCAGGCGGTTG
CGCATCATCTCACCGGTGAGCAAATCGACCTCACCCACAGAACCAACGCCAGCAATAACCCCCAAAGCCTTGCATTCAAC
GGTTTTCTGGATCATCTACAGGGCATGGTCGGCAGAATGGCATCTACGGGAGATAAGCTGACTCAGCTCAGTAACAGGTT
GCACGATTCCATGTCTGGGGTGAATAACCGCATGAAACTGCAGCACAACCAAATCGATGTCATCGCCCACGCTGTGGGCA
ATGTCAGCGATGCAGTGAGACTGATTTCAGACAACGCCAACGATGCTTCGGCAGCCGTCAGCGATGCAGACGCAAAATCC
CGGGATGGCTCTGCGTTAAGCCGCAAAACCCTTGATGAAGTCCTTACGCTGGCAAATGCCATTGAACGCGCCGCCGACGC
CAGCGGTCGCCTGGCCGAAGACAGCAAAAGCATTGGCAAAGTGCTGGATGTGATAAAAAGTATTGCGGAACAAACCAATC
TGTTGGCGCTTAACGCCGCCATCGAGGCCGCCCGGGCCGGAGAGCAGGGACGTGGCTTTGCGGTAGTGGCCGACGAAGTG
CGAAGCCTCGCATCCAAAACACAGCAGTCAACCGAAGAAATTCACAACATGATCCAACGTCTGCAAGCCCGCAGCGATGA
TGCCGTTAACGCCATGTCAACCAGTCAAACGAGCGTGACCCAGTGCGTTGCCTTTACCCAACAAACCGATGAAAGACTTG
GCCAGGTACGTCAATCCCTGCAGCAGATTGTAGAAATCAGCAGTCAAATCGCGAGCTCAACTACAGAACAAATGCAAGCA
ATCGGGGAAATAAGTCAGAACGCATTGAGCATCAGGCAGCTCAGTGATGACAACAATCATGAGCTTGATAGGGTTGTGGA
TGAAGTTGCAGAAGCAACCGGGCTCGCGGGCCTTATTCACTCCGATATGAAGCGTTTTCATACCGGCTTATAA

Upstream 100 bases:

>100_bases
GCGGTTCGGGTGCCGATTTACTGCGTGAAGCACTGCTCAATGCGGCGGGTGAATCTTTGCCACTGCTCGATTGGCCAATT
CAGGTGTCCTGCCATTGCCG

Downstream 100 bases:

>100_bases
CTGATATAAAAAAGACAGGGTTCCCTGTCTTTTTTTAAACCAACCTTTGTCCGGAATACCGGGCAGTTTGGCCGTTACTT
ATAGAAAGCTTCCACTTCGC

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MAHLNSASMAAPVFTARLTCPLKWRVSTKMNNLSSEMMRDHYIKSDTIMFSVLVMMFLYALGLAGVFGNWTVAIIVGLLT
TIAAGAIRALSPGERITRVTMGLAFMVMVTLHVHLSRGMIEMHFGYFACLAMLLYCRDWLPILASALLAAVLHVGLFWWQ
TTGGSVFMLDSAERSWGIIFIHAGYVVVETLVLVVMAKNLHRQAEVSFDIQAVAHHLTGEQIDLTHRTNASNNPQSLAFN
GFLDHLQGMVGRMASTGDKLTQLSNRLHDSMSGVNNRMKLQHNQIDVIAHAVGNVSDAVRLISDNANDASAAVSDADAKS
RDGSALSRKTLDEVLTLANAIERAADASGRLAEDSKSIGKVLDVIKSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEV
RSLASKTQQSTEEIHNMIQRLQARSDDAVNAMSTSQTSVTQCVAFTQQTDERLGQVRQSLQQIVEISSQIASSTTEQMQA
IGEISQNALSIRQLSDDNNHELDRVVDEVAEATGLAGLIHSDMKRFHTGL

Sequences:

>Translated_530_residues
MAHLNSASMAAPVFTARLTCPLKWRVSTKMNNLSSEMMRDHYIKSDTIMFSVLVMMFLYALGLAGVFGNWTVAIIVGLLT
TIAAGAIRALSPGERITRVTMGLAFMVMVTLHVHLSRGMIEMHFGYFACLAMLLYCRDWLPILASALLAAVLHVGLFWWQ
TTGGSVFMLDSAERSWGIIFIHAGYVVVETLVLVVMAKNLHRQAEVSFDIQAVAHHLTGEQIDLTHRTNASNNPQSLAFN
GFLDHLQGMVGRMASTGDKLTQLSNRLHDSMSGVNNRMKLQHNQIDVIAHAVGNVSDAVRLISDNANDASAAVSDADAKS
RDGSALSRKTLDEVLTLANAIERAADASGRLAEDSKSIGKVLDVIKSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEV
RSLASKTQQSTEEIHNMIQRLQARSDDAVNAMSTSQTSVTQCVAFTQQTDERLGQVRQSLQQIVEISSQIASSTTEQMQA
IGEISQNALSIRQLSDDNNHELDRVVDEVAEATGLAGLIHSDMKRFHTGL
>Mature_529_residues
AHLNSASMAAPVFTARLTCPLKWRVSTKMNNLSSEMMRDHYIKSDTIMFSVLVMMFLYALGLAGVFGNWTVAIIVGLLTT
IAAGAIRALSPGERITRVTMGLAFMVMVTLHVHLSRGMIEMHFGYFACLAMLLYCRDWLPILASALLAAVLHVGLFWWQT
TGGSVFMLDSAERSWGIIFIHAGYVVVETLVLVVMAKNLHRQAEVSFDIQAVAHHLTGEQIDLTHRTNASNNPQSLAFNG
FLDHLQGMVGRMASTGDKLTQLSNRLHDSMSGVNNRMKLQHNQIDVIAHAVGNVSDAVRLISDNANDASAAVSDADAKSR
DGSALSRKTLDEVLTLANAIERAADASGRLAEDSKSIGKVLDVIKSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVR
SLASKTQQSTEEIHNMIQRLQARSDDAVNAMSTSQTSVTQCVAFTQQTDERLGQVRQSLQQIVEISSQIASSTTEQMQAI
GEISQNALSIRQLSDDNNHELDRVVDEVAEATGLAGLIHSDMKRFHTGL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=260, Percent_Identity=31.1538461538462, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1788195, Length=237, Percent_Identity=32.4894514767932, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788194, Length=163, Percent_Identity=38.6503067484663, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI2367378, Length=275, Percent_Identity=29.0909090909091, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789453, Length=243, Percent_Identity=31.6872427983539, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 57599; Mature: 57467

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHLNSASMAAPVFTARLTCPLKWRVSTKMNNLSSEMMRDHYIKSDTIMFSVLVMMFLYA
CCCCCCCHHHHHHHHHHEECCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LGLAGVFGNWTVAIIVGLLTTIAAGAIRALSPGERITRVTMGLAFMVMVTLHVHLSRGMI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
EMHFGYFACLAMLLYCRDWLPILASALLAAVLHVGLFWWQTTGGSVFMLDSAERSWGIIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCCCEEE
IHAGYVVVETLVLVVMAKNLHRQAEVSFDIQAVAHHLTGEQIDLTHRTNASNNPQSLAFN
EECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHH
GFLDHLQGMVGRMASTGDKLTQLSNRLHDSMSGVNNRMKLQHNQIDVIAHAVGNVSDAVR
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHCCHHHHHH
LISDNANDASAAVSDADAKSRDGSALSRKTLDEVLTLANAIERAADASGRLAEDSKSIGK
HHHCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VLDVIKSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASKTQQSTEEIHNMIQR
HHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
LQARSDDAVNAMSTSQTSVTQCVAFTQQTDERLGQVRQSLQQIVEISSQIASSTTEQMQA
HHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGEISQNALSIRQLSDDNNHELDRVVDEVAEATGLAGLIHSDMKRFHTGL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AHLNSASMAAPVFTARLTCPLKWRVSTKMNNLSSEMMRDHYIKSDTIMFSVLVMMFLYA
CCCCCCHHHHHHHHHHEECCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LGLAGVFGNWTVAIIVGLLTTIAAGAIRALSPGERITRVTMGLAFMVMVTLHVHLSRGMI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
EMHFGYFACLAMLLYCRDWLPILASALLAAVLHVGLFWWQTTGGSVFMLDSAERSWGIIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCCCEEE
IHAGYVVVETLVLVVMAKNLHRQAEVSFDIQAVAHHLTGEQIDLTHRTNASNNPQSLAFN
EECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHH
GFLDHLQGMVGRMASTGDKLTQLSNRLHDSMSGVNNRMKLQHNQIDVIAHAVGNVSDAVR
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHCCHHHHHH
LISDNANDASAAVSDADAKSRDGSALSRKTLDEVLTLANAIERAADASGRLAEDSKSIGK
HHHCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VLDVIKSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASKTQQSTEEIHNMIQR
HHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
LQARSDDAVNAMSTSQTSVTQCVAFTQQTDERLGQVRQSLQQIVEISSQIASSTTEQMQA
HHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGEISQNALSIRQLSDDNNHELDRVVDEVAEATGLAGLIHSDMKRFHTGL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]