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The map label for this gene is dctD [H]

Identifier: 119775348

GI number: 119775348

Start: 2675092

End: 2676477

Strand: Direct

Name: dctD [H]

Synonym: Sama_2213

Alternate gene names: 119775348

Gene position: 2675092-2676477 (Clockwise)

Preceding gene: 119775347

Following gene: 119775350

Centisome position: 62.12

GC content: 56.13

Gene sequence:

>1386_bases
ATGAGTCTTGAAACCCTGACAAACATCCAGGTGCTTATCGTGGATGATGAGCCCCATATCGGCACTGTGCTGATGCAACT
TTTTGAGCTGAATGGCTTGAATGCCGAGGCCACCACAGATCCTCACCTGGCGATTAGCCTGATTGACCGCGATTGGCCGG
GTGTAGTGATTACCGACGTCAACATGCCTGGCATGGATGGCATTTCGCTGCTGGCGCAATGCATCCGGATAGATGCCGAC
CTGCCTGTGGTGCTGCTGACCGGTTTCGGCGACATCGCCATGGCCGTTAGCGCGCTCAAGCAAGGTGCCTACGACTTTCT
CGAAAAGCCATTCAATAACGAGCATATGCTGGATGTGGTCAAACGGGCGCTGGAAAAACGCAGCCTGACGCTGGAAAACC
GCAAGCTGAAAAAGCAGCTCGAGTCACACGCCATCCCCGGCCCAAGGATTTTGGGCAACAGCCCGGGCATAGTTCGGCTG
AGAAACCTCATTGATATGGTCGTCAATACCCCGGCCGATGTGCTGATTGAAGGGGAAACAGGCACAGGTAAAGAGTTGGT
CGCCCGCTGCCTGCACGACCACAGCCCGAGGCACCAGGCCAATTTTGTGGCAATCAATTGCGGCGCCATCCCCGAAAACC
TGATTGAAAGCGAGCTCTTCGGTGCCGAAGCCGGCGCCTTCACCGGCATCGACAAGGCCCGGGTCGGCAAGTTCGAATTT
GCCAATGGCGGCACCCTGTTTTTGGATGAAATCGAGTCCACGCCCCTGTCGCTGCAGGTAAAACTGCTCAGGGTACTGGA
AGACAGGAAGGTTGAGCGACTGGGCTCCAACAAGAGTATTCCACTGGATATCCGGGTGGTGGCCGCCACCAAGGTGGACC
TGAAACAGCTGTGCGATAAAGGGGAATTCCGCCAGGACTTACTCTATCGACTGAATCTGGTCACCATCCCTATTCCTCCA
CTAAAAGAGAGACGGGAAGATATTCCCCTGCTGTTTCTGCACTTTGCCCGCATTGCCTCGGCCCGTTATCACAAGGAACT
TATCTTCCCCAGTGCCGAGCATCATGCCCGCATGACGGCCCACGACTGGCCGGGGAATGTGCGGGAGCTGAGAAACCTTG
CCGAGCGCTATGTGCTCCTTGGCGCCGAGTCGGCATTTGCCGCCAGCCTCGGCGGCCATGCCCAGCTGCAATCCGGCATG
TCCTTGAGTCAGCGGGTAGAGTTTTTCGAGCGCATGTTGATTGAAGAAGCCCTGAGTCACAATCGCGGCTCTATCAAGCA
AACCATGGAGCAGTTGGAGCTGCCCCGCAAAACCCTGTACGACAAGATGCGCAAGTACGATCTGGACCGCAAGCACTACC
TTAACGATACGCAGGAAGAGGCATAG

Upstream 100 bases:

>100_bases
ATCGAATCCATGCAAGGGGATATCCGGGTCGCCAACGCGCCTGAGGGCGGTGCCATCTTCGATATCACTCTGCCCGCTTA
TTTAGCCGACAAGGGACAAT

Downstream 100 bases:

>100_bases
CACCCTTGCCGCGACGCAGGGCAAACCAAGCAAAAACCGCAGTAACGCCAAGCACTATCAAAGAGCCATAAACAACGCCG
GCCCAGCCAGCCTGATGCCA

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MSLETLTNIQVLIVDDEPHIGTVLMQLFELNGLNAEATTDPHLAISLIDRDWPGVVITDVNMPGMDGISLLAQCIRIDAD
LPVVLLTGFGDIAMAVSALKQGAYDFLEKPFNNEHMLDVVKRALEKRSLTLENRKLKKQLESHAIPGPRILGNSPGIVRL
RNLIDMVVNTPADVLIEGETGTGKELVARCLHDHSPRHQANFVAINCGAIPENLIESELFGAEAGAFTGIDKARVGKFEF
ANGGTLFLDEIESTPLSLQVKLLRVLEDRKVERLGSNKSIPLDIRVVAATKVDLKQLCDKGEFRQDLLYRLNLVTIPIPP
LKERREDIPLLFLHFARIASARYHKELIFPSAEHHARMTAHDWPGNVRELRNLAERYVLLGAESAFAASLGGHAQLQSGM
SLSQRVEFFERMLIEEALSHNRGSIKQTMEQLELPRKTLYDKMRKYDLDRKHYLNDTQEEA

Sequences:

>Translated_461_residues
MSLETLTNIQVLIVDDEPHIGTVLMQLFELNGLNAEATTDPHLAISLIDRDWPGVVITDVNMPGMDGISLLAQCIRIDAD
LPVVLLTGFGDIAMAVSALKQGAYDFLEKPFNNEHMLDVVKRALEKRSLTLENRKLKKQLESHAIPGPRILGNSPGIVRL
RNLIDMVVNTPADVLIEGETGTGKELVARCLHDHSPRHQANFVAINCGAIPENLIESELFGAEAGAFTGIDKARVGKFEF
ANGGTLFLDEIESTPLSLQVKLLRVLEDRKVERLGSNKSIPLDIRVVAATKVDLKQLCDKGEFRQDLLYRLNLVTIPIPP
LKERREDIPLLFLHFARIASARYHKELIFPSAEHHARMTAHDWPGNVRELRNLAERYVLLGAESAFAASLGGHAQLQSGM
SLSQRVEFFERMLIEEALSHNRGSIKQTMEQLELPRKTLYDKMRKYDLDRKHYLNDTQEEA
>Mature_460_residues
SLETLTNIQVLIVDDEPHIGTVLMQLFELNGLNAEATTDPHLAISLIDRDWPGVVITDVNMPGMDGISLLAQCIRIDADL
PVVLLTGFGDIAMAVSALKQGAYDFLEKPFNNEHMLDVVKRALEKRSLTLENRKLKKQLESHAIPGPRILGNSPGIVRLR
NLIDMVVNTPADVLIEGETGTGKELVARCLHDHSPRHQANFVAINCGAIPENLIESELFGAEAGAFTGIDKARVGKFEFA
NGGTLFLDEIESTPLSLQVKLLRVLEDRKVERLGSNKSIPLDIRVVAATKVDLKQLCDKGEFRQDLLYRLNLVTIPIPPL
KERREDIPLLFLHFARIASARYHKELIFPSAEHHARMTAHDWPGNVRELRNLAERYVLLGAESAFAASLGGHAQLQSGMS
LSQRVEFFERMLIEEALSHNRGSIKQTMEQLELPRKTLYDKMRKYDLDRKHYLNDTQEEA

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=453, Percent_Identity=37.9690949227373, Blast_Score=312, Evalue=2e-86,
Organism=Escherichia coli, GI1790299, Length=469, Percent_Identity=37.7398720682303, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI1788905, Length=446, Percent_Identity=36.9955156950673, Blast_Score=287, Evalue=1e-78,
Organism=Escherichia coli, GI1790437, Length=448, Percent_Identity=37.7232142857143, Blast_Score=281, Evalue=6e-77,
Organism=Escherichia coli, GI87082117, Length=255, Percent_Identity=48.6274509803922, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1789087, Length=332, Percent_Identity=41.2650602409639, Blast_Score=228, Evalue=6e-61,
Organism=Escherichia coli, GI1789233, Length=323, Percent_Identity=39.938080495356, Blast_Score=214, Evalue=8e-57,
Organism=Escherichia coli, GI1786524, Length=244, Percent_Identity=46.3114754098361, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI87082152, Length=238, Percent_Identity=44.1176470588235, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=45.4545454545455, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1787583, Length=358, Percent_Identity=33.2402234636872, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI87081858, Length=310, Percent_Identity=30.3225806451613, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1789828, Length=236, Percent_Identity=36.4406779661017, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786599, Length=121, Percent_Identity=28.9256198347107, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51634; Mature: 51503

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLETLTNIQVLIVDDEPHIGTVLMQLFELNGLNAEATTDPHLAISLIDRDWPGVVITDV
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEEEEC
NMPGMDGISLLAQCIRIDADLPVVLLTGFGDIAMAVSALKQGAYDFLEKPFNNEHMLDVV
CCCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
KRALEKRSLTLENRKLKKQLESHAIPGPRILGNSPGIVRLRNLIDMVVNTPADVLIEGET
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHCCCCCEEEECCC
GTGKELVARCLHDHSPRHQANFVAINCGAIPENLIESELFGAEAGAFTGIDKARVGKFEF
CCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHCCCEEE
ANGGTLFLDEIESTPLSLQVKLLRVLEDRKVERLGSNKSIPLDIRVVAATKVDLKQLCDK
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHCC
GEFRQDLLYRLNLVTIPIPPLKERREDIPLLFLHFARIASARYHKELIFPSAEHHARMTA
CCHHHHHHHHHEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCC
HDWPGNVRELRNLAERYVLLGAESAFAASLGGHAQLQSGMSLSQRVEFFERMLIEEALSH
CCCCCCHHHHHHHHHHHEEECCCHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHC
NRGSIKQTMEQLELPRKTLYDKMRKYDLDRKHYLNDTQEEA
CCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHCCCCCCCC
>Mature Secondary Structure 
SLETLTNIQVLIVDDEPHIGTVLMQLFELNGLNAEATTDPHLAISLIDRDWPGVVITDV
CCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEEEEC
NMPGMDGISLLAQCIRIDADLPVVLLTGFGDIAMAVSALKQGAYDFLEKPFNNEHMLDVV
CCCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
KRALEKRSLTLENRKLKKQLESHAIPGPRILGNSPGIVRLRNLIDMVVNTPADVLIEGET
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHCCCCCEEEECCC
GTGKELVARCLHDHSPRHQANFVAINCGAIPENLIESELFGAEAGAFTGIDKARVGKFEF
CCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHCCCEEE
ANGGTLFLDEIESTPLSLQVKLLRVLEDRKVERLGSNKSIPLDIRVVAATKVDLKQLCDK
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHCC
GEFRQDLLYRLNLVTIPIPPLKERREDIPLLFLHFARIASARYHKELIFPSAEHHARMTA
CCHHHHHHHHHEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCC
HDWPGNVRELRNLAERYVLLGAESAFAASLGGHAQLQSGMSLSQRVEFFERMLIEEALSH
CCCCCCHHHHHHHHHHHEEECCCHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHC
NRGSIKQTMEQLELPRKTLYDKMRKYDLDRKHYLNDTQEEA
CCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]