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The map label for this gene is dctB [H]

Identifier: 119775347

GI number: 119775347

Start: 2673300

End: 2675102

Strand: Direct

Name: dctB [H]

Synonym: Sama_2212

Alternate gene names: 119775347

Gene position: 2673300-2675102 (Clockwise)

Preceding gene: 119775346

Following gene: 119775348

Centisome position: 62.08

GC content: 56.07

Gene sequence:

>1803_bases
ATGCAGATGACAGCGCAAATTCATCGACGCCTTCGTTACACCCTGCTCGCCCTCGTAGGCCTGGTGGGCGTGTTATATCT
GACCTGGAGCTGGCATGTACGAAGTGGCGTGTCAGATCTGGCCGACACCTCCCGCGCTCAGCTGGGTGAGCTGGTCAGCC
TGCTCGATGGCATGCTGTCGCGCTTTGAAACCATTCCCCACGTGTTGTCGACCAACCCCATGCTGGCCGATACCCTGCTC
AACCAACGCGACATGGACAAGGTCCACAGACTCAATAAATACCTCGAGGAGCTAAGGCATATTACCGAGGCCTCCGACAT
TTACCTTATCGATGCCCTTGGGGTTGCCGTTGCCGCCAGCAACTGGCAGCAATCCTATTCATTTGTTGGTCAGGATTATT
CGTTCAGGCCTTACTTCACCGAGGCCATCGCCGGGCGTCAGGGCAATTACTATGCGGTGGGAACCGCTTCTGATAAGCGG
GGCTATTACTTTTCTTTTCCGGTGGAAGACAGCGGCACAGTACTTGGCGCCATCGTGGTGAAACTGGACGTGCTGGACAT
TGAAACCCAGGCCTCAGGGGTCGCACAGGCGGGTCAGTATGACTTTATTATCACGGATCCCGATAACATAGTCTTTGCCT
CCAACAGGGCCGAATGGCGACTTACGTCACTGGGCCCCTTCACCGACAGCAAACGCTACGCCCTCAATGCCAGTAAAAGG
TACGCAAAGCGACAAATCACAGAGCTGGATATTCATCCGGCTTACAAGGGGGTCACCGAAGGCGTCAATGCCTATCGGAT
TGGCAGCGGGCTCAAAGCAGCAGACTATCTCGACACCTCAACTGCCATGATCAAGGCAGGTTGGCGTGTGCACGTATTGA
CGCCACTGGCACCCGTGTATAGCTCCTTGTCGCAGGTGCTGCTGCTGTCTGCCACCTGCTATGGTCTGCTGCTGCTTTTT
ACCCTGCTGCAGCGGGAGCGTCGCCACAGCCTGGCCAGAATGCAGCAATCCCGCGATGAGCTGGAACAACGGGTGAAAGA
GCGCACCGCCGAGCTTGAAGCGGCAAACACCCAGCTCAAAGATACCCAGGATGAGCTTATTCAGGCCGCCAAGCTAACGG
TAGTCGGCACCATGTCGGCCAGTATCAACCATGAGCTCAATCAGCCGCTGGCGGCCATTCGAAGCTATACCCAAAACACC
CAAACCTTTTTGGAACGGGATATGCCCGGCCGTGCCCGAGAAAATCTGGCGATTATTCTTGAGCTTACCGACCGACTCGC
CGACATTGTCGGCCAATTTAAAAGCTTTACCCGCAAAAGCCAGGGCAAAGACGGCGTGGTTATGCTCGCCAACTGCTTAC
AGCAGGCCCTGACCATAGTGCAGCCCGAACTGGACAAACAAAAAGCCCAACTGACGATCCACTGTGAGGATGAATCCCTC
AAAGTCTGGTGCGACGGCACCCGCCTGCAGCAGGTGCTGGTTAACCTCATCACCAACGCCCTGAATGCCATGTCGCAAAG
CCCGGTGAAGCGTCTGTCCATCAGTTTACTCGGGGGCGATCCCGTCACCATACGCATCCAGGACTCAGGCCCCGGGGTGC
GTGACAGCCTGATGGAAAAAATCTTTGAGCCCTATTACACCACCAGCGAGCGGCAGGGGCTGGGGCTCGGGCTGTCTATT
TCGCGCCGTATTATCGAATCCATGCAAGGGGATATCCGGGTCGCCAACGCGCCTGAGGGCGGTGCCATCTTCGATATCAC
TCTGCCCGCTTATTTAGCCGACAAGGGACAATATGAGTCTTGA

Upstream 100 bases:

>100_bases
TTTAAATAATCCCTGGCTGCACTGTTGATCCAAAGTGTATTTTAAGCGAGCCTAAGCCATAGATTTACTATGGCTTTTGC
CTTTTTGAGAACCGCCGTAC

Downstream 100 bases:

>100_bases
AACCCTGACAAACATCCAGGTGCTTATCGTGGATGATGAGCCCCATATCGGCACTGTGCTGATGCAACTTTTTGAGCTGA
ATGGCTTGAATGCCGAGGCC

Product: putative two-component sensor histidine kinase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 600; Mature: 600

Protein sequence:

>600_residues
MQMTAQIHRRLRYTLLALVGLVGVLYLTWSWHVRSGVSDLADTSRAQLGELVSLLDGMLSRFETIPHVLSTNPMLADTLL
NQRDMDKVHRLNKYLEELRHITEASDIYLIDALGVAVAASNWQQSYSFVGQDYSFRPYFTEAIAGRQGNYYAVGTASDKR
GYYFSFPVEDSGTVLGAIVVKLDVLDIETQASGVAQAGQYDFIITDPDNIVFASNRAEWRLTSLGPFTDSKRYALNASKR
YAKRQITELDIHPAYKGVTEGVNAYRIGSGLKAADYLDTSTAMIKAGWRVHVLTPLAPVYSSLSQVLLLSATCYGLLLLF
TLLQRERRHSLARMQQSRDELEQRVKERTAELEAANTQLKDTQDELIQAAKLTVVGTMSASINHELNQPLAAIRSYTQNT
QTFLERDMPGRARENLAIILELTDRLADIVGQFKSFTRKSQGKDGVVMLANCLQQALTIVQPELDKQKAQLTIHCEDESL
KVWCDGTRLQQVLVNLITNALNAMSQSPVKRLSISLLGGDPVTIRIQDSGPGVRDSLMEKIFEPYYTTSERQGLGLGLSI
SRRIIESMQGDIRVANAPEGGAIFDITLPAYLADKGQYES

Sequences:

>Translated_600_residues
MQMTAQIHRRLRYTLLALVGLVGVLYLTWSWHVRSGVSDLADTSRAQLGELVSLLDGMLSRFETIPHVLSTNPMLADTLL
NQRDMDKVHRLNKYLEELRHITEASDIYLIDALGVAVAASNWQQSYSFVGQDYSFRPYFTEAIAGRQGNYYAVGTASDKR
GYYFSFPVEDSGTVLGAIVVKLDVLDIETQASGVAQAGQYDFIITDPDNIVFASNRAEWRLTSLGPFTDSKRYALNASKR
YAKRQITELDIHPAYKGVTEGVNAYRIGSGLKAADYLDTSTAMIKAGWRVHVLTPLAPVYSSLSQVLLLSATCYGLLLLF
TLLQRERRHSLARMQQSRDELEQRVKERTAELEAANTQLKDTQDELIQAAKLTVVGTMSASINHELNQPLAAIRSYTQNT
QTFLERDMPGRARENLAIILELTDRLADIVGQFKSFTRKSQGKDGVVMLANCLQQALTIVQPELDKQKAQLTIHCEDESL
KVWCDGTRLQQVLVNLITNALNAMSQSPVKRLSISLLGGDPVTIRIQDSGPGVRDSLMEKIFEPYYTTSERQGLGLGLSI
SRRIIESMQGDIRVANAPEGGAIFDITLPAYLADKGQYES
>Mature_600_residues
MQMTAQIHRRLRYTLLALVGLVGVLYLTWSWHVRSGVSDLADTSRAQLGELVSLLDGMLSRFETIPHVLSTNPMLADTLL
NQRDMDKVHRLNKYLEELRHITEASDIYLIDALGVAVAASNWQQSYSFVGQDYSFRPYFTEAIAGRQGNYYAVGTASDKR
GYYFSFPVEDSGTVLGAIVVKLDVLDIETQASGVAQAGQYDFIITDPDNIVFASNRAEWRLTSLGPFTDSKRYALNASKR
YAKRQITELDIHPAYKGVTEGVNAYRIGSGLKAADYLDTSTAMIKAGWRVHVLTPLAPVYSSLSQVLLLSATCYGLLLLF
TLLQRERRHSLARMQQSRDELEQRVKERTAELEAANTQLKDTQDELIQAAKLTVVGTMSASINHELNQPLAAIRSYTQNT
QTFLERDMPGRARENLAIILELTDRLADIVGQFKSFTRKSQGKDGVVMLANCLQQALTIVQPELDKQKAQLTIHCEDESL
KVWCDGTRLQQVLVNLITNALNAMSQSPVKRLSISLLGGDPVTIRIQDSGPGVRDSLMEKIFEPYYTTSERQGLGLGLSI
SRRIIESMQGDIRVANAPEGGAIFDITLPAYLADKGQYES

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=233, Percent_Identity=33.0472103004292, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=30.7692307692308, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87081816, Length=279, Percent_Identity=26.5232974910394, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI48994928, Length=247, Percent_Identity=29.1497975708502, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI145693157, Length=138, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788393, Length=221, Percent_Identity=28.5067873303167, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1789149, Length=264, Percent_Identity=25, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1790346, Length=274, Percent_Identity=25.9124087591241, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788713, Length=125, Percent_Identity=33.6, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790300, Length=251, Percent_Identity=27.0916334661355, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786912, Length=217, Percent_Identity=24.8847926267281, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1790861, Length=215, Percent_Identity=26.046511627907, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66775; Mature: 66775

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMTAQIHRRLRYTLLALVGLVGVLYLTWSWHVRSGVSDLADTSRAQLGELVSLLDGMLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RFETIPHVLSTNPMLADTLLNQRDMDKVHRLNKYLEELRHITEASDIYLIDALGVAVAAS
HHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHH
NWQQSYSFVGQDYSFRPYFTEAIAGRQGNYYAVGTASDKRGYYFSFPVEDSGTVLGAIVV
HHHHHHHHHCCCCCCCCHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCEEEEE
KLDVLDIETQASGVAQAGQYDFIITDPDNIVFASNRAEWRLTSLGPFTDSKRYALNASKR
EEEEEEECHHHCCHHCCCCEEEEEECCCCEEEECCCCCEEEEECCCCCCCCCEEECHHHH
YAKRQITELDIHPAYKGVTEGVNAYRIGSGLKAADYLDTSTAMIKAGWRVHVLTPLAPVY
HHHHHHHHEECCCHHHHHHCCCCEEEECCCCCHHHHCCCCHHHHCCCCEEEEECCHHHHH
SSLSQVLLLSATCYGLLLLFTLLQRERRHSLARMQQSRDELEQRVKERTAELEAANTQLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DTQDELIQAAKLTVVGTMSASINHELNQPLAAIRSYTQNTQTFLERDMPGRARENLAIIL
CCHHHHHHHHHHEEEEECCHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
ELTDRLADIVGQFKSFTRKSQGKDGVVMLANCLQQALTIVQPELDKQKAQLTIHCEDESL
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCE
KVWCDGTRLQQVLVNLITNALNAMSQSPVKRLSISLLGGDPVTIRIQDSGPGVRDSLMEK
EEEECCHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCEEEEEEECCCCCHHHHHHHH
IFEPYYTTSERQGLGLGLSISRRIIESMQGDIRVANAPEGGAIFDITLPAYLADKGQYES
HHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCEEEEEECHHHHCCCCCCCC
>Mature Secondary Structure
MQMTAQIHRRLRYTLLALVGLVGVLYLTWSWHVRSGVSDLADTSRAQLGELVSLLDGMLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RFETIPHVLSTNPMLADTLLNQRDMDKVHRLNKYLEELRHITEASDIYLIDALGVAVAAS
HHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHH
NWQQSYSFVGQDYSFRPYFTEAIAGRQGNYYAVGTASDKRGYYFSFPVEDSGTVLGAIVV
HHHHHHHHHCCCCCCCCHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCEEEEE
KLDVLDIETQASGVAQAGQYDFIITDPDNIVFASNRAEWRLTSLGPFTDSKRYALNASKR
EEEEEEECHHHCCHHCCCCEEEEEECCCCEEEECCCCCEEEEECCCCCCCCCEEECHHHH
YAKRQITELDIHPAYKGVTEGVNAYRIGSGLKAADYLDTSTAMIKAGWRVHVLTPLAPVY
HHHHHHHHEECCCHHHHHHCCCCEEEECCCCCHHHHCCCCHHHHCCCCEEEEECCHHHHH
SSLSQVLLLSATCYGLLLLFTLLQRERRHSLARMQQSRDELEQRVKERTAELEAANTQLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DTQDELIQAAKLTVVGTMSASINHELNQPLAAIRSYTQNTQTFLERDMPGRARENLAIIL
CCHHHHHHHHHHEEEEECCHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
ELTDRLADIVGQFKSFTRKSQGKDGVVMLANCLQQALTIVQPELDKQKAQLTIHCEDESL
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCE
KVWCDGTRLQQVLVNLITNALNAMSQSPVKRLSISLLGGDPVTIRIQDSGPGVRDSLMEK
EEEECCHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCEEEEEEECCCCCHHHHHHHH
IFEPYYTTSERQGLGLGLSISRRIIESMQGDIRVANAPEGGAIFDITLPAYLADKGQYES
HHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCEEEEEECHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3671068 [H]