Click here to switch to the map view.

The map label for this gene is sstT

Identifier: 119775335

GI number: 119775335

Start: 2657360

End: 2658577

Strand: Reverse

Name: sstT

Synonym: Sama_2200

Alternate gene names: 119775335

Gene position: 2658577-2657360 (Counterclockwise)

Preceding gene: 119775336

Following gene: 119775334

Centisome position: 61.74

GC content: 56.81

Gene sequence:

>1218_bases
ATGAGTACTGAAAAATCATTGCTGGCAAATGCTGCCGGTGGCAGCCTGGTGCTGCAAATTTTTGTGGGGATCATCGCCGG
TGTGGCCCTGGCCGGATTCAGCCCTGAGGCTGCCAATCAGGTCGCTTTCCTGGGTGACCTCTTTGTGGGAGCGCTCAAGG
CCATCGCGCCCGTACTGGTGTTTGTGCTGGTTGCATCGTCAATCGCCAATCAGGTGTCAGGTGCGCAGACCAATATGCGT
CCCATCATCCTGTTATATCTGGTGGGTACCTTTGCTGCGGCGCTGACGGCGGTACTGATGAGTTTTGCCTTCCCGACCAG
CCTTGTTCTGATTGATGCGGCCGCAGGCGCCAATCCGCCAGAGGGGATAGGTCAGGTGCTCAACACCTTGCTGTTCAAAC
TGGTGGATAACCCGGTTAATGCCCTGATTAACGCCAACTATATTGGTCTGCTCGCATGGGGTGTGGGGCTGGGCATCGCG
CTGCGTCACGCAAGCACCAGCACCAAAAACATGCTGCATGATGTCAGCCACGGCGTGTCTCAGCTGGTGCGTTTCGTTAT
CTGTCTCGCACCGATAGGGATTTTTGGCCTGGTGGCTGCCACTATCGCTCAAACCGGCTTTGAGGCCCTGGCGGCCTATG
CCCAACTGCTTGGCGTATTGCTTGGGGCCATGGCAGTGATAGCCTTTGTGGTTAACCCGCTGATTGTATTTTTGAAAATT
CGTCGCAACCCTTATCCGTTGGTGTTCAAGTGCCTGCGCGAAAGTGGTGTTACTGCGTTCTTTACCCGCTCCAGCGCAGC
CAATATTCCGGTGAACATGGCGCTCTGCGAGCGTCTAAAGCTGCATGAGGATACTTACTCAGTCTCTATCCCCCTGGGGG
CGACCATCAATATGGCCGGTGCCGCCATCACCATCACCGTGCTCACGCTGGCGGCTGTGCATACCCTGGGTATTGAAGTC
GACCTGGCCACAGCGCTGTTGCTCAGTGTTATTGCGGCTGTTTCGGCCTGCGGCGCTTCAGGCGTGGCCGGTGGCTCTTT
GCTGCTTATCCCGCTTGCGTGCTCCTTGTTTGGCATTTCCAACGATATCGCGATGCAGGTAGTGGCCGTAGGCTTCACCA
TAGGCGTCATCCAGGACAGCGCTGAGACCGCACTGAACAGTTCCACCGACGTGCTCTTTACCGCAGCGGCCTGTGAAGCG
GCAGAGCGCAAAGCCTAA

Upstream 100 bases:

>100_bases
TTGCTGGACAAAGCCTCTGCTTTTCGATACAACCCAAAGCCGGGATGCAAAGTCCTTAAGGCCCCAGTGGCCCATAACGA
TAACAACGACAGGTCAAGTC

Downstream 100 bases:

>100_bases
GTTGCTAACAATGACAAATGGCTGAAAAAGCGGCAGTATTAAGTTACTGCCGCTTTTTTATTGTCAGCGAAAAAGATCCC
GGGAGGTCACAGATGCGACT

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSTEKSLLANAAGGSLVLQIFVGIIAGVALAGFSPEAANQVAFLGDLFVGALKAIAPVLVFVLVASSIANQVSGAQTNMR
PIILLYLVGTFAAALTAVLMSFAFPTSLVLIDAAAGANPPEGIGQVLNTLLFKLVDNPVNALINANYIGLLAWGVGLGIA
LRHASTSTKNMLHDVSHGVSQLVRFVICLAPIGIFGLVAATIAQTGFEALAAYAQLLGVLLGAMAVIAFVVNPLIVFLKI
RRNPYPLVFKCLRESGVTAFFTRSSAANIPVNMALCERLKLHEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIEV
DLATALLLSVIAAVSACGASGVAGGSLLLIPLACSLFGISNDIAMQVVAVGFTIGVIQDSAETALNSSTDVLFTAAACEA
AERKA

Sequences:

>Translated_405_residues
MSTEKSLLANAAGGSLVLQIFVGIIAGVALAGFSPEAANQVAFLGDLFVGALKAIAPVLVFVLVASSIANQVSGAQTNMR
PIILLYLVGTFAAALTAVLMSFAFPTSLVLIDAAAGANPPEGIGQVLNTLLFKLVDNPVNALINANYIGLLAWGVGLGIA
LRHASTSTKNMLHDVSHGVSQLVRFVICLAPIGIFGLVAATIAQTGFEALAAYAQLLGVLLGAMAVIAFVVNPLIVFLKI
RRNPYPLVFKCLRESGVTAFFTRSSAANIPVNMALCERLKLHEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIEV
DLATALLLSVIAAVSACGASGVAGGSLLLIPLACSLFGISNDIAMQVVAVGFTIGVIQDSAETALNSSTDVLFTAAACEA
AERKA
>Mature_404_residues
STEKSLLANAAGGSLVLQIFVGIIAGVALAGFSPEAANQVAFLGDLFVGALKAIAPVLVFVLVASSIANQVSGAQTNMRP
IILLYLVGTFAAALTAVLMSFAFPTSLVLIDAAAGANPPEGIGQVLNTLLFKLVDNPVNALINANYIGLLAWGVGLGIAL
RHASTSTKNMLHDVSHGVSQLVRFVICLAPIGIFGLVAATIAQTGFEALAAYAQLLGVLLGAMAVIAFVVNPLIVFLKIR
RNPYPLVFKCLRESGVTAFFTRSSAANIPVNMALCERLKLHEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIEVD
LATALLLSVIAAVSACGASGVAGGSLLLIPLACSLFGISNDIAMQVVAVGFTIGVIQDSAETALNSSTDVLFTAAACEAA
ERKA

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family

Homologues:

Organism=Homo sapiens, GI4827012, Length=267, Percent_Identity=25.4681647940075, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI223468564, Length=256, Percent_Identity=28.515625, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI223468566, Length=256, Percent_Identity=28.515625, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI5032093, Length=256, Percent_Identity=28.515625, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI66773030, Length=232, Percent_Identity=22.8448275862069, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI21314632, Length=259, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI169790839, Length=267, Percent_Identity=23.9700374531835, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789473, Length=406, Percent_Identity=66.5024630541872, Blast_Score=516, Evalue=1e-148,
Organism=Escherichia coli, GI1789947, Length=361, Percent_Identity=25.7617728531856, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790514, Length=423, Percent_Identity=21.7494089834515, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17537407, Length=430, Percent_Identity=24.6511627906977, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71996953, Length=269, Percent_Identity=28.2527881040892, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71983099, Length=276, Percent_Identity=25.3623188405797, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71983106, Length=276, Percent_Identity=25.3623188405797, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193206505, Length=424, Percent_Identity=23.1132075471698, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583025, Length=433, Percent_Identity=24.7113163972286, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17137668, Length=433, Percent_Identity=24.7113163972286, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583023, Length=433, Percent_Identity=24.7113163972286, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SSTT_SHEAM (A1S7P9)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_928075.1
- ProteinModelPortal:   A1S7P9
- SMR:   A1S7P9
- STRING:   A1S7P9
- GeneID:   4604450
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_2200
- NMPDR:   fig|326297.7.peg.2067
- eggNOG:   COG3633
- HOGENOM:   HBG289387
- OMA:   THIRPIL
- PhylomeDB:   A1S7P9
- ProtClustDB:   PRK13628
- HAMAP:   MF_01582
- InterPro:   IPR001991
- InterPro:   IPR023025
- PANTHER:   PTHR11958
- PRINTS:   PR00173

Pfam domain/function: PF00375 SDF

EC number: NA

Molecular weight: Translated: 41414; Mature: 41283

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1; PS00714 NA_DICARBOXYL_SYMP_2; PS00435 PEROXIDASE_1 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13db0e34)-; HASH(0x14b6996c)-; HASH(0x148546f0)-; HASH(0x14b2c8dc)-; HASH(0x14c75a20)-; HASH(0x14d17bc8)-; HASH(0x13f16d30)-; HASH(0x14c0bda4)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEHHHHHHHHCCH
>Mature Secondary Structure 
STEKSLLANAAGGSLVLQIFVGIIAGVALAGFSPEAANQVAFLGDLFVGALKAIAPVLV
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FVLVASSIANQVSGAQTNMRPIILLYLVGTFAAALTAVLMSFAFPTSLVLIDAAAGANPP
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCH
EGIGQVLNTLLFKLVDNPVNALINANYIGLLAWGVGLGIALRHASTSTKNMLHDVSHGVS
HHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QLVRFVICLAPIGIFGLVAATIAQTGFEALAAYAQLLGVLLGAMAVIAFVVNPLIVFLKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRNPYPLVFKCLRESGVTAFFTRSSAANIPVNMALCERLKLHEDTYSVSIPLGATINMAG
CCCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEECCC
AAITITVLTLAAVHTLGIEVDLATALLLSVIAAVSACGASGVAGGSLLLIPLACSLFGIS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
NDIAMQVVAVGFTIGVIQDSAETALNSSTDVLFTAAACEAAERKA
CHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA