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The map label for this gene is rimK [H]

Identifier: 119775134

GI number: 119775134

Start: 2428478

End: 2429407

Strand: Direct

Name: rimK [H]

Synonym: Sama_1999

Alternate gene names: 119775134

Gene position: 2428478-2429407 (Clockwise)

Preceding gene: 119775133

Following gene: 119775135

Centisome position: 56.4

GC content: 50.22

Gene sequence:

>930_bases
ATGCGCGGCTGGATTTTATATAAAGAAACCGCGACTCAGCTCAAACCCGAACTGTACGAAATTCAACGTCTGTTGGACGC
CGCCAAGGCGGACAACATAGATCTGCAGGTCTATGCCCCGGACGAGTTTGATTTGACCGTTACCCGGGAAGACAACAAGA
GTATTTTGCTTAATGGGCAGCCGGTTGAGCTGCCCGATTTTATTATTCCCCGCATGGGTTCAGGCACGACCTATTTTGCG
CTGGCGATTATTCGTCACCTTGAGCGCTTGGGCGTTTACAGCCTCAACTCATCACGGGCTATCGAGACCGTAAAAGACAA
ACTCTTCTCACAGCAGCTATTGGCCGAAAAAAATCTGCCAACGCCCAAAACCATGCTGGTGAAGTTCCCGGTGGATATAG
AACTGGTGCAAAGCCATTTGGGCTTTCCTGTGGTGATAAAAACCTTGTCCGGCTCCCAGGGCAGTGGTGTGTTTTTGTCA
CATAAACCACGGGAGTTTGACGATCTGATGCAGTTGATTGAGGCCACCAATAAAAACGCCAACATCATATTGCAGGAGTT
TATTGCCAACAGTCATGGACGGGATCTTCGGGTCTTTACCATTGGCGGGCGAGTCGTGGGCTGTTTTGAGCGGCGTGCGG
CGGAAGACAGCTTCAAGGCCAATGTCAGTGCCGGTGGAGCCGCGCTTCCCTTTGAGGTCACCCCCGAGATTGAATGGCTC
GCGACCCAAACAGCCAATATCCTCGACCTGGATGTGGCTGGTATCGACTTACTGTTCGATAACGGTCACTACAAAATATG
TGAAGCCAACTCCTCACCGGGATTCGAAGGTCTCGAATCTTGCCTTAATGTGGATATCGCATCACAAATCCTCCACTTTA
TTCGCATCCGGCTTGGGATGTTCAATAAAGAAGACCAACACTCAATATGA

Upstream 100 bases:

>100_bases
CACCTGAGGCTGAAATTGAACTCGATGATATCGACGATGACGAGGTTTCTGATGACGAGGAACCCGAGGACACACCATGA
CGCTTAAGGCGAATATCTGA

Downstream 100 bases:

>100_bases
GAACAAAAGCACCCTAATGGGTGCTTTTTTGTTCAGGGTCAAAGTTTTTCACAATTTTGCAAACAAATGTTTCACAATCT
TTTGCCTTTGTGGTTAAACT

Product: ribosomal protein S6 modification protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MRGWILYKETATQLKPELYEIQRLLDAAKADNIDLQVYAPDEFDLTVTREDNKSILLNGQPVELPDFIIPRMGSGTTYFA
LAIIRHLERLGVYSLNSSRAIETVKDKLFSQQLLAEKNLPTPKTMLVKFPVDIELVQSHLGFPVVIKTLSGSQGSGVFLS
HKPREFDDLMQLIEATNKNANIILQEFIANSHGRDLRVFTIGGRVVGCFERRAAEDSFKANVSAGGAALPFEVTPEIEWL
ATQTANILDLDVAGIDLLFDNGHYKICEANSSPGFEGLESCLNVDIASQILHFIRIRLGMFNKEDQHSI

Sequences:

>Translated_309_residues
MRGWILYKETATQLKPELYEIQRLLDAAKADNIDLQVYAPDEFDLTVTREDNKSILLNGQPVELPDFIIPRMGSGTTYFA
LAIIRHLERLGVYSLNSSRAIETVKDKLFSQQLLAEKNLPTPKTMLVKFPVDIELVQSHLGFPVVIKTLSGSQGSGVFLS
HKPREFDDLMQLIEATNKNANIILQEFIANSHGRDLRVFTIGGRVVGCFERRAAEDSFKANVSAGGAALPFEVTPEIEWL
ATQTANILDLDVAGIDLLFDNGHYKICEANSSPGFEGLESCLNVDIASQILHFIRIRLGMFNKEDQHSI
>Mature_309_residues
MRGWILYKETATQLKPELYEIQRLLDAAKADNIDLQVYAPDEFDLTVTREDNKSILLNGQPVELPDFIIPRMGSGTTYFA
LAIIRHLERLGVYSLNSSRAIETVKDKLFSQQLLAEKNLPTPKTMLVKFPVDIELVQSHLGFPVVIKTLSGSQGSGVFLS
HKPREFDDLMQLIEATNKNANIILQEFIANSHGRDLRVFTIGGRVVGCFERRAAEDSFKANVSAGGAALPFEVTPEIEWL
ATQTANILDLDVAGIDLLFDNGHYKICEANSSPGFEGLESCLNVDIASQILHFIRIRLGMFNKEDQHSI

Specific function: Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 [H]

COG id: COG0189

COG function: function code HJ; Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI134254462, Length=302, Percent_Identity=30.794701986755, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI164663810, Length=297, Percent_Identity=27.2727272727273, Blast_Score=115, Evalue=4e-26,
Organism=Escherichia coli, GI1787076, Length=278, Percent_Identity=34.8920863309352, Blast_Score=167, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013651
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR004666 [H]

Pfam domain/function: PF08443 RimK [H]

EC number: NA

Molecular weight: Translated: 34477; Mature: 34477

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGWILYKETATQLKPELYEIQRLLDAAKADNIDLQVYAPDEFDLTVTREDNKSILLNGQ
CCCEEEECCHHHHHCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCEEEECCC
PVELPDFIIPRMGSGTTYFALAIIRHLERLGVYSLNSSRAIETVKDKLFSQQLLAEKNLP
CCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHCCCC
TPKTMLVKFPVDIELVQSHLGFPVVIKTLSGSQGSGVFLSHKPREFDDLMQLIEATNKNA
CCCEEEEECCCCHHHHHHHCCCEEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCCC
NIILQEFIANSHGRDLRVFTIGGRVVGCFERRAAEDSFKANVSAGGAALPFEVTPEIEWL
CEEHHHHHCCCCCCEEEEEEECCEEEEHHHHHCCCCCCEEECCCCCEECCEEECCCEEEE
ATQTANILDLDVAGIDLLFDNGHYKICEANSSPGFEGLESCLNVDIASQILHFIRIRLGM
EECCCCEEEEEECCEEEEEECCCEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCC
FNKEDQHSI
CCCCCCCCC
>Mature Secondary Structure
MRGWILYKETATQLKPELYEIQRLLDAAKADNIDLQVYAPDEFDLTVTREDNKSILLNGQ
CCCEEEECCHHHHHCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCEEEECCC
PVELPDFIIPRMGSGTTYFALAIIRHLERLGVYSLNSSRAIETVKDKLFSQQLLAEKNLP
CCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHCCCC
TPKTMLVKFPVDIELVQSHLGFPVVIKTLSGSQGSGVFLSHKPREFDDLMQLIEATNKNA
CCCEEEEECCCCHHHHHHHCCCEEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCCC
NIILQEFIANSHGRDLRVFTIGGRVVGCFERRAAEDSFKANVSAGGAALPFEVTPEIEWL
CEEHHHHHCCCCCCEEEEEEECCEEEEHHHHHCCCCCCEEECCCCCEECCEEECCCEEEE
ATQTANILDLDVAGIDLLFDNGHYKICEANSSPGFEGLESCLNVDIASQILHFIRIRLGM
EECCCCEEEEEECCEEEEEECCCEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCC
FNKEDQHSI
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Glu; Ribosomal protein S6 [C]

Specific reaction: Catalyzes the addition of glutamic acids to the carboxyl end of ribosomal protein S6 [C]

General reaction: Ligases; Forming Carbon-Nitrogen Bonds; Acid-D-Amino-Acid Ligases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA