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The map label for this gene is adrA [H]

Identifier: 119775084

GI number: 119775084

Start: 2376276

End: 2377259

Strand: Reverse

Name: adrA [H]

Synonym: Sama_1949

Alternate gene names: 119775084

Gene position: 2377259-2376276 (Counterclockwise)

Preceding gene: 119775085

Following gene: 119775075

Centisome position: 55.21

GC content: 51.32

Gene sequence:

>984_bases
ATGTTGCCCGCACCCATTCCCTTCGATGAGGCCGAAAGGCTTGAGGCGCTTCGTAGCCTGAATGTACTGGACACAGAGGC
TGAAGAGCGTTTCGATCGCCTCACCCGCTTGGCGCGCAGGCTGTTTGATGTCCCAATCTGCCTGATAAGCCTGGTCGATT
CTGACAGGCAATGGTTTAAATCCTGTATCGGTTTGTCCCAGTCTGAAACCCGCCGTGACATCTCCTTTTGCGGCCATGCC
ATTATGCAAGCCGATATCTTTGTAATTGAAGATGCGCTCGAAGACTTAAGATTTGCCGATAATCCTCTGGTGACTGGGGA
GCCCCATATTCGTTTTTATGCAGGCTATCCGCTGACCTTGAGTAACGGTCACAGAGTTGGCACTCTGTGCATTATTGACC
GGAAAGCTCGTCGTTTTGAGCCTGAGGATTATTGCGATCTGGAAGATCTCGGTAAGTTGGTGGTATCGGAGCTCGAAGCG
GTACAAACCGCGACCCTGGATCCCTTAACGGGCCTGTCAAATCTGCGCGGGTTCGATCTTCTCGCCAAACAGTGCCTTGC
CAAGTGTCAGCGGCAACAGCAGGATGCGACCCTGTTTTTTCTGGACCTTGATTATTTCAAGGAAATCAATGACCGATTTG
GGCATCAGGAAGGCAACAGTGCCCTCGTGGCATTCGCCAGCCTGCTTAAAGAAGCATTTCGTGAGTACGATGTGATTGCC
CGTATAGGCGGTGATGAGTTTGTTGCGCTGGTTAGCCATGAACGGTCAATGTCGCCAGCGGCGGGGATCTTAAGCCGCTT
GCGTCATAACCTGGCCAGGCACAATATTGATACTCCCATTGGTTATCAGCTGGAATTCAGCTGCGGTACTGCCCGTTTTG
ATGCGCTGTTACCAAGCTCTCTTGAGCGGTTACTTGAAGATGCGGACATCCATATGTACCGCGAAAAGCAAATTCATCAC
CAAAAGCATGACGAGCAGAACTGA

Upstream 100 bases:

>100_bases
TGCTTAAAACCCGGCCAGAGGGCCAGGCGTCTATTTACGATTGACGCTAAATTCCTTGCGGGCAACTATACTTACCCGAA
GTTAGCCTTTCGGAGTCTTC

Downstream 100 bases:

>100_bases
ATCAGGGCCAGACACCTTAGCGGTCACCGTCGGTGTCGGACGAAAGAAATACCATTTGAAAAGACAAACAAAAAACGCTG
CCATGGCAGCGTTTTTACGT

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MLPAPIPFDEAERLEALRSLNVLDTEAEERFDRLTRLARRLFDVPICLISLVDSDRQWFKSCIGLSQSETRRDISFCGHA
IMQADIFVIEDALEDLRFADNPLVTGEPHIRFYAGYPLTLSNGHRVGTLCIIDRKARRFEPEDYCDLEDLGKLVVSELEA
VQTATLDPLTGLSNLRGFDLLAKQCLAKCQRQQQDATLFFLDLDYFKEINDRFGHQEGNSALVAFASLLKEAFREYDVIA
RIGGDEFVALVSHERSMSPAAGILSRLRHNLARHNIDTPIGYQLEFSCGTARFDALLPSSLERLLEDADIHMYREKQIHH
QKHDEQN

Sequences:

>Translated_327_residues
MLPAPIPFDEAERLEALRSLNVLDTEAEERFDRLTRLARRLFDVPICLISLVDSDRQWFKSCIGLSQSETRRDISFCGHA
IMQADIFVIEDALEDLRFADNPLVTGEPHIRFYAGYPLTLSNGHRVGTLCIIDRKARRFEPEDYCDLEDLGKLVVSELEA
VQTATLDPLTGLSNLRGFDLLAKQCLAKCQRQQQDATLFFLDLDYFKEINDRFGHQEGNSALVAFASLLKEAFREYDVIA
RIGGDEFVALVSHERSMSPAAGILSRLRHNLARHNIDTPIGYQLEFSCGTARFDALLPSSLERLLEDADIHMYREKQIHH
QKHDEQN
>Mature_327_residues
MLPAPIPFDEAERLEALRSLNVLDTEAEERFDRLTRLARRLFDVPICLISLVDSDRQWFKSCIGLSQSETRRDISFCGHA
IMQADIFVIEDALEDLRFADNPLVTGEPHIRFYAGYPLTLSNGHRVGTLCIIDRKARRFEPEDYCDLEDLGKLVVSELEA
VQTATLDPLTGLSNLRGFDLLAKQCLAKCQRQQQDATLFFLDLDYFKEINDRFGHQEGNSALVAFASLLKEAFREYDVIA
RIGGDEFVALVSHERSMSPAAGILSRLRHNLARHNIDTPIGYQLEFSCGTARFDALLPSSLERLLEDADIHMYREKQIHH
QKHDEQN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=154, Percent_Identity=33.1168831168831, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082007, Length=172, Percent_Identity=33.7209302325581, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081977, Length=265, Percent_Identity=27.5471698113208, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787802, Length=137, Percent_Identity=30.6569343065693, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788381, Length=135, Percent_Identity=31.8518518518519, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693134, Length=154, Percent_Identity=29.8701298701299, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788956, Length=183, Percent_Identity=30.6010928961749, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87081881, Length=173, Percent_Identity=28.9017341040462, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787262, Length=161, Percent_Identity=27.3291925465839, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 37283; Mature: 37283

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPAPIPFDEAERLEALRSLNVLDTEAEERFDRLTRLARRLFDVPICLISLVDSDRQWFK
CCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
SCIGLSQSETRRDISFCGHAIMQADIFVIEDALEDLRFADNPLVTGEPHIRFYAGYPLTL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEE
SNGHRVGTLCIIDRKARRFEPEDYCDLEDLGKLVVSELEAVQTATLDPLTGLSNLRGFDL
CCCCEEEEEEEEECHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCHHHCCHHHH
LAKQCLAKCQRQQQDATLFFLDLDYFKEINDRFGHQEGNSALVAFASLLKEAFREYDVIA
HHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RIGGDEFVALVSHERSMSPAAGILSRLRHNLARHNIDTPIGYQLEFSCGTARFDALLPSS
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHH
LERLLEDADIHMYREKQIHHQKHDEQN
HHHHHHHCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLPAPIPFDEAERLEALRSLNVLDTEAEERFDRLTRLARRLFDVPICLISLVDSDRQWFK
CCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
SCIGLSQSETRRDISFCGHAIMQADIFVIEDALEDLRFADNPLVTGEPHIRFYAGYPLTL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEE
SNGHRVGTLCIIDRKARRFEPEDYCDLEDLGKLVVSELEAVQTATLDPLTGLSNLRGFDL
CCCCEEEEEEEEECHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCHHHCCHHHH
LAKQCLAKCQRQQQDATLFFLDLDYFKEINDRFGHQEGNSALVAFASLLKEAFREYDVIA
HHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RIGGDEFVALVSHERSMSPAAGILSRLRHNLARHNIDTPIGYQLEFSCGTARFDALLPSS
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHH
LERLLEDADIHMYREKQIHHQKHDEQN
HHHHHHHCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]