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The map label for this gene is msbB [H]

Identifier: 119775085

GI number: 119775085

Start: 2377316

End: 2378242

Strand: Reverse

Name: msbB [H]

Synonym: Sama_1950

Alternate gene names: 119775085

Gene position: 2378242-2377316 (Counterclockwise)

Preceding gene: 119775086

Following gene: 119775084

Centisome position: 55.23

GC content: 53.51

Gene sequence:

>927_bases
ATGCGTTATTTTGACAGACGATTTTACTGGGGACTCCTGCATCCAAGACTGTGGGGAACCTGGGTTGCCATCGGCGTCTT
GCTCTTTTTTGGCGCCTTGCCTGCCGCTATTCGCGATCCCATCGCGCGTGGTCTGTCCGGGCTGGTACTGGGTATCGCTA
AAAAGCCAATCCGGGTAGCAAGGGCCAATATTAAGGCTTGTTTCCCTGACAAATCAGATAGGGAAGTGGAGGCGCTAATT
CGTGAGAATGTAGCGCAGTTCGTGATGATCCTGATTGGGCAGGCCGAGCTCCTGTTCGGCAGTGACGCTCATTTACGCCG
CCGCGTTTCGCTGCACGGCTTTGAGCACGTGAAAGCTGCCCGCGACGCTGGGCAGCCAATTATTTTCATTATGCCCCATG
TATGGGGTATAGATTACGCCGGGCTTAGGTTAAACCTTGAGGTACCGATGGCGACCATGGCCAAGGCGCATCGTAATGAA
CTCTTTAATTGGTTTTCCAACCGTATCCGCAGTCGCCTTGGCGGCCATGTCTACATGCGTGAGGCGGGTCTTAGAGTGCT
AATCAGCGAGATGCGCCAGGGGAACAGCTTCTTTTACTTACCTGACGAAGATTTAGGGCCAGATCAAAGCGTATTTGCAC
CGCTTTTCGCTACCACTAAGGCCACATTACCAGTGGTAGGGAGGCTGGCTGCAGCCGGTAAAGCCCAGGTGATGCCGGTG
ACCATTGGTTACGATGATAAGGCTCACCGGTTTTCACTCACCGTGCTGCCCGCTATCGACGAAGCGACCATGGCAGGCAA
AGAAAATGAAGCACTGGCGCTCAACCGCGCTGTTGAGCAGGTTATTTCGGCCTACCCTGAGCAGTATATGTGGTTTTTAA
AGCTGCTTAAAACCCGGCCAGAGGGCCAGGCGTCTATTTACGATTGA

Upstream 100 bases:

>100_bases
ATCCAACTCCGAAAAGTAACATCGGAATACACTGAGGGAAGGCCACTCATCTGAGTGGCTTTCCTGTTTGTGTGCTCTAA
AGAGATTCTAAGTTAAGACA

Downstream 100 bases:

>100_bases
CGCTAAATTCCTTGCGGGCAACTATACTTACCCGAAGTTAGCCTTTCGGAGTCTTCATGTTGCCCGCACCCATTCCCTTC
GATGAGGCCGAAAGGCTTGA

Product: lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MRYFDRRFYWGLLHPRLWGTWVAIGVLLFFGALPAAIRDPIARGLSGLVLGIAKKPIRVARANIKACFPDKSDREVEALI
RENVAQFVMILIGQAELLFGSDAHLRRRVSLHGFEHVKAARDAGQPIIFIMPHVWGIDYAGLRLNLEVPMATMAKAHRNE
LFNWFSNRIRSRLGGHVYMREAGLRVLISEMRQGNSFFYLPDEDLGPDQSVFAPLFATTKATLPVVGRLAAAGKAQVMPV
TIGYDDKAHRFSLTVLPAIDEATMAGKENEALALNRAVEQVISAYPEQYMWFLKLLKTRPEGQASIYD

Sequences:

>Translated_308_residues
MRYFDRRFYWGLLHPRLWGTWVAIGVLLFFGALPAAIRDPIARGLSGLVLGIAKKPIRVARANIKACFPDKSDREVEALI
RENVAQFVMILIGQAELLFGSDAHLRRRVSLHGFEHVKAARDAGQPIIFIMPHVWGIDYAGLRLNLEVPMATMAKAHRNE
LFNWFSNRIRSRLGGHVYMREAGLRVLISEMRQGNSFFYLPDEDLGPDQSVFAPLFATTKATLPVVGRLAAAGKAQVMPV
TIGYDDKAHRFSLTVLPAIDEATMAGKENEALALNRAVEQVISAYPEQYMWFLKLLKTRPEGQASIYD
>Mature_308_residues
MRYFDRRFYWGLLHPRLWGTWVAIGVLLFFGALPAAIRDPIARGLSGLVLGIAKKPIRVARANIKACFPDKSDREVEALI
RENVAQFVMILIGQAELLFGSDAHLRRRVSLHGFEHVKAARDAGQPIIFIMPHVWGIDYAGLRLNLEVPMATMAKAHRNE
LFNWFSNRIRSRLGGHVYMREAGLRVLISEMRQGNSFFYLPDEDLGPDQSVFAPLFATTKATLPVVGRLAAAGKAQVMPV
TIGYDDKAHRFSLTVLPAIDEATMAGKENEALALNRAVEQVISAYPEQYMWFLKLLKTRPEGQASIYD

Specific function: Transfers myristate or laurate, activated on ACP, to (KDO)2-(lauroyl)-lipid IVA [H]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI1788161, Length=305, Percent_Identity=35.4098360655738, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1787292, Length=302, Percent_Identity=29.4701986754967, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI87082094, Length=310, Percent_Identity=29.6774193548387, Blast_Score=143, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011921 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 34605; Mature: 34605

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYFDRRFYWGLLHPRLWGTWVAIGVLLFFGALPAAIRDPIARGLSGLVLGIAKKPIRVA
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
RANIKACFPDKSDREVEALIRENVAQFVMILIGQAELLFGSDAHLRRRVSLHGFEHVKAA
HCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHCCHHHHHHH
RDAGQPIIFIMPHVWGIDYAGLRLNLEVPMATMAKAHRNELFNWFSNRIRSRLGGHVYMR
HHCCCCEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEH
EAGLRVLISEMRQGNSFFYLPDEDLGPDQSVFAPLFATTKATLPVVGRLAAAGKAQVMPV
HHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
TIGYDDKAHRFSLTVLPAIDEATMAGKENEALALNRAVEQVISAYPEQYMWFLKLLKTRP
EECCCCCCCEEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
EGQASIYD
CCCCCCCC
>Mature Secondary Structure
MRYFDRRFYWGLLHPRLWGTWVAIGVLLFFGALPAAIRDPIARGLSGLVLGIAKKPIRVA
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
RANIKACFPDKSDREVEALIRENVAQFVMILIGQAELLFGSDAHLRRRVSLHGFEHVKAA
HCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHCCHHHHHHH
RDAGQPIIFIMPHVWGIDYAGLRLNLEVPMATMAKAHRNELFNWFSNRIRSRLGGHVYMR
HHCCCCEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEH
EAGLRVLISEMRQGNSFFYLPDEDLGPDQSVFAPLFATTKATLPVVGRLAAAGKAQVMPV
HHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
TIGYDDKAHRFSLTVLPAIDEATMAGKENEALALNRAVEQVISAYPEQYMWFLKLLKTRP
EECCCCCCCEEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
EGQASIYD
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]