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The map label for this gene is ruvA

Identifier: 119774975

GI number: 119774975

Start: 2241369

End: 2241986

Strand: Reverse

Name: ruvA

Synonym: Sama_1840

Alternate gene names: 119774975

Gene position: 2241986-2241369 (Counterclockwise)

Preceding gene: 119774976

Following gene: 119774974

Centisome position: 52.06

GC content: 52.75

Gene sequence:

>618_bases
ATGATAGGTCGTTTAAAGGGCATTTTGGTTGAGAAACACGCCCCAGAGGTATTGATAGATGTGGGCGGTGTTGGCTATGA
GCTGCAAATGCCGCTGACCTCCTTTTACGAGCTGCCACTGCCTGGCGCCGAGGTCATTGTTTATACCCATTTTGTGGTCC
GTGAAGATGCTCAGCTTTTGTATGGATTTATCCATAAAGAAGAGCGCTCACTGTTTCGTTTGCTGATCAAGGCCAATGGT
GTTGGCCCCAAGCTCGCGCTCACTATTCTGTCGGGCATGACCGCCAAAGAGTTTATTGGTTGCCTGGAACGTGACGATAT
CGCGACCCTGATTAAGCTGCCCGGTGTGGGTAAAAAGACTGCCGAACGTCTGCTGGTTGAGATGCGCGACAAACTCAAGA
GCCTGATGGAAGCCTCCATGGGCGCTGAGCGAGAGTTTGTGCTTAAGAGCAACTTCACACCGGCGCCGGTGGCTGCCACT
GTGGAAGAAGATGCCATAGCCGCGCTCTTGTCATTGGGCTACAAACCGCAGCAGGCAAGCAAAGCCGTATCCAGTGCCTT
CCAGGAGGGCATGGATCCCGAGCAGCTTATCAAGGCTGCACTTAAGTCCATGCTCTAA

Upstream 100 bases:

>100_bases
CGGCAGATGCACTGGCGGTTGCCATGTGTCATTATCACACCCATCAAAGTCTGGTGGCCCTCGGTGGGCGCGCCAGTGTC
AGAACATACGGAAGATACAG

Downstream 100 bases:

>100_bases
GGTGAAAGGGGAATACCATGATTGAAGCCGACCGGCTTATTCAGCCCCAGGATCTGGGTCAGGAAGATGTGATTGACCGC
GCCATGCGGCCAAAATTACT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MIGRLKGILVEKHAPEVLIDVGGVGYELQMPLTSFYELPLPGAEVIVYTHFVVREDAQLLYGFIHKEERSLFRLLIKANG
VGPKLALTILSGMTAKEFIGCLERDDIATLIKLPGVGKKTAERLLVEMRDKLKSLMEASMGAEREFVLKSNFTPAPVAAT
VEEDAIAALLSLGYKPQQASKAVSSAFQEGMDPEQLIKAALKSML

Sequences:

>Translated_205_residues
MIGRLKGILVEKHAPEVLIDVGGVGYELQMPLTSFYELPLPGAEVIVYTHFVVREDAQLLYGFIHKEERSLFRLLIKANG
VGPKLALTILSGMTAKEFIGCLERDDIATLIKLPGVGKKTAERLLVEMRDKLKSLMEASMGAEREFVLKSNFTPAPVAAT
VEEDAIAALLSLGYKPQQASKAVSSAFQEGMDPEQLIKAALKSML
>Mature_205_residues
MIGRLKGILVEKHAPEVLIDVGGVGYELQMPLTSFYELPLPGAEVIVYTHFVVREDAQLLYGFIHKEERSLFRLLIKANG
VGPKLALTILSGMTAKEFIGCLERDDIATLIKLPGVGKKTAERLLVEMRDKLKSLMEASMGAEREFVLKSNFTPAPVAAT
VEEDAIAALLSLGYKPQQASKAVSSAFQEGMDPEQLIKAALKSML

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=205, Percent_Identity=58.0487804878049, Blast_Score=239, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_SHEAM (A1S6N9)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927715.1
- ProteinModelPortal:   A1S6N9
- SMR:   A1S6N9
- STRING:   A1S6N9
- GeneID:   4604090
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1840
- NMPDR:   fig|326297.7.peg.1732
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- PhylomeDB:   A1S6N9
- ProtClustDB:   PRK00116
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 22402; Mature: 22402

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRLKGILVEKHAPEVLIDVGGVGYELQMPLTSFYELPLPGAEVIVYTHFVVREDAQLL
CCCCHHHHEEECCCCEEEEEECCCCEEEECCHHHHHCCCCCCCCEEEEEHHHHHHHHHHH
YGFIHKEERSLFRLLIKANGVGPKLALTILSGMTAKEFIGCLERDDIATLIKLPGVGKKT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHCCCCCHHH
AERLLVEMRDKLKSLMEASMGAEREFVLKSNFTPAPVAATVEEDAIAALLSLGYKPQQAS
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHH
KAVSSAFQEGMDPEQLIKAALKSML
HHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIGRLKGILVEKHAPEVLIDVGGVGYELQMPLTSFYELPLPGAEVIVYTHFVVREDAQLL
CCCCHHHHEEECCCCEEEEEECCCCEEEECCHHHHHCCCCCCCCEEEEEHHHHHHHHHHH
YGFIHKEERSLFRLLIKANGVGPKLALTILSGMTAKEFIGCLERDDIATLIKLPGVGKKT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHCCCCCHHH
AERLLVEMRDKLKSLMEASMGAEREFVLKSNFTPAPVAATVEEDAIAALLSLGYKPQQAS
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHH
KAVSSAFQEGMDPEQLIKAALKSML
HHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA