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The map label for this gene is ruvC

Identifier: 119774976

GI number: 119774976

Start: 2241983

End: 2242504

Strand: Reverse

Name: ruvC

Synonym: Sama_1841

Alternate gene names: 119774976

Gene position: 2242504-2241983 (Counterclockwise)

Preceding gene: 119774977

Following gene: 119774975

Centisome position: 52.08

GC content: 57.09

Gene sequence:

>522_bases
ATGGCCATTATTTTAGGAGTCGACCCGGGCTCACGCATCACAGGTTATGGGGTTATCCAGTGTCAGGGCAGGCATCAGCT
CTATCTTGGCAGCGGTTGTATTCGTACTTCATCGGATGAACTGCCCGACAGGCTTAAGCAGATTTTTGATGGTCTGCAGG
AAATTATCCGTCAGTACCAGCCGAGCCAGTTTGCCATCGAGCGGGTCTTTATGGCCAAGAATGCCGACTCGGCATTGAAG
CTAGGCCAGGCGAGGGGCGCTGCCATAGTCGCCGCCACAGTGGCAGGTTTGCCGGTGGCGGAATACAGCGCCACCCAGAT
TAAAAATGCCGTGGTGGGCACAGGCCGGGCACAAAAGGCTCAGGTGCAGCACATGGTGCAGCAGATGCTGAAACTCCCCG
CAGCGCCCCAGGCCGACGCGGCAGATGCACTGGCGGTTGCCATGTGTCATTATCACACCCATCAAAGTCTGGTGGCCCTC
GGTGGGCGCGCCAGTGTCAGAACATACGGAAGATACAGATGA

Upstream 100 bases:

>100_bases
CCTGCGGCTTATCGATCAGCTTGAAGATCATGATGATGTGCAGGAGGTTTACCATAACGCCGACATCCCCGATGAGGTGA
TGGAGACGCTGGAATAATCC

Downstream 100 bases:

>100_bases
TAGGTCGTTTAAAGGGCATTTTGGTTGAGAAACACGCCCCAGAGGTATTGATAGATGTGGGCGGTGTTGGCTATGAGCTG
CAAATGCCGCTGACCTCCTT

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MAIILGVDPGSRITGYGVIQCQGRHQLYLGSGCIRTSSDELPDRLKQIFDGLQEIIRQYQPSQFAIERVFMAKNADSALK
LGQARGAAIVAATVAGLPVAEYSATQIKNAVVGTGRAQKAQVQHMVQQMLKLPAAPQADAADALAVAMCHYHTHQSLVAL
GGRASVRTYGRYR

Sequences:

>Translated_173_residues
MAIILGVDPGSRITGYGVIQCQGRHQLYLGSGCIRTSSDELPDRLKQIFDGLQEIIRQYQPSQFAIERVFMAKNADSALK
LGQARGAAIVAATVAGLPVAEYSATQIKNAVVGTGRAQKAQVQHMVQQMLKLPAAPQADAADALAVAMCHYHTHQSLVAL
GGRASVRTYGRYR
>Mature_172_residues
AIILGVDPGSRITGYGVIQCQGRHQLYLGSGCIRTSSDELPDRLKQIFDGLQEIIRQYQPSQFAIERVFMAKNADSALKL
GQARGAAIVAATVAGLPVAEYSATQIKNAVVGTGRAQKAQVQHMVQQMLKLPAAPQADAADALAVAMCHYHTHQSLVALG
GRASVRTYGRYR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=156, Percent_Identity=69.2307692307692, Blast_Score=198, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_SHEAM (A1S6P0)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927716.1
- ProteinModelPortal:   A1S6P0
- SMR:   A1S6P0
- STRING:   A1S6P0
- GeneID:   4604091
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1841
- eggNOG:   COG0817
- HOGENOM:   HBG437552
- OMA:   PMQIKLA
- PhylomeDB:   A1S6P0
- ProtClustDB:   PRK00039
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 18578; Mature: 18446

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIILGVDPGSRITGYGVIQCQGRHQLYLGSGCIRTSSDELPDRLKQIFDGLQEIIRQYQ
CEEEEECCCCCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
PSQFAIERVFMAKNADSALKLGQARGAAIVAATVAGLPVAEYSATQIKNAVVGTGRAQKA
CHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEHHHHCCCCCHHHHHHHHHHHHCCCCHHHH
QVQHMVQQMLKLPAAPQADAADALAVAMCHYHTHQSLVALGGRASVRTYGRYR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AIILGVDPGSRITGYGVIQCQGRHQLYLGSGCIRTSSDELPDRLKQIFDGLQEIIRQYQ
EEEEECCCCCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
PSQFAIERVFMAKNADSALKLGQARGAAIVAATVAGLPVAEYSATQIKNAVVGTGRAQKA
CHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEHHHHCCCCCHHHHHHHHHHHHCCCCHHHH
QVQHMVQQMLKLPAAPQADAADALAVAMCHYHTHQSLVALGGRASVRTYGRYR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA